Clinical Trials on Genetic Predisposition to Disease

Total 16819 results

Nuon Therapeutics, Inc.

Completed

Tranilast Plus Allopurinol in Patients With Moderate to Severe Gout (TAnGO)

Hyperuricemia | Moderate to Severe Gout

United States
Istituto Clinico Humanitas

Active, not recruiting

Study on SBRT for Inoperable Lung and Liver Oligometastases From Breast Cancer

Breast Cancer | Metastasis to Liver | Metastasis to Lung

Italy
Carnegie Mellon University

Not yet recruiting

Heads up Messages to Increase Call Pick-up Rates

Various: Health Insurance Members That Could Benefit From Being Connected to a Specialist, e.g., Orthopedic Doctor to Treat Back Pain
Cairo University
Ain Shams University hospitals

Unknown

Effectiveness of N-acetyl Cysteine, Acetyl L- Carnitine and Medicated Paraffin Oil in Aluminium Phosphide Poisoning

the Study Focus to Improve the Standard of Care Used for Aluminuim Phosphide Poisoning and to Save Patients With the Minimal Organ Damage

Egypt
ALK-Abelló A/S

Active, not recruiting

House Dust Mite Allergy Trial In Children (MATIC)

Allergic Rhinitis Due to Dermatophagoides Farinae | Allergic Rhinitis Due to Dermatophagoides Pteronyssinus | Allergic Rhinitis Due to House Dust Mite

Spain, Russian Federation, United States, Poland, Bulgaria, Canada, France, Germany, Lithuania, Slovakia, Ukraine
Tonix Pharmaceuticals, Inc.
Premier Research Group plc

Active, not recruiting

Assessment of Delayed-type Hypersensitivity Reactions to SARS-CoV-2 Peptide Antigens (COVID-19 DTH)

Detection of Delayed-type Hypersensitivity Reactions to SARS-CoV-2 in Individuals Exposed to SARS-CoV-2

United States
Servier Hellas Pharmaceuticals Ltd.

Completed

Study for the Recording of Adherence to Treatment With Perindopril/Indapamide/Amlodipine Fixed Dose Combination (CONTROL-3)

Hypertensive Disease | Adherence to Medication Regime

Greece
Xiaofan Zhu

Available

Use Massive Parallel Sequencing and Exome Capture Technology to Sequence the Exome of Fanconi Anemia Children and Their Patents

Fanconi Anemia | Autosomal or Sex Linked Recessive Genetic Disease | Bone Marrow Hematopoiesis Failure, Multiple Congenital Abnormalities, and Susceptibility to Neoplastic Diseases. | Hematopoiesis Maintainance.

China
University of Michigan
Genentech, Inc.

Terminated

Studying the Treatment Effect of Pirfenidone in Chronic Lung Allograft Dysfunction (STOP-CLAD)

Chronic Lung Allograft Dysfunction | Disorder Related to Lung Transplantation

United States
University of Washington
National Institute of Mental Health (NIMH); Kenyatta National Hospital

Active, not recruiting

Planning the mPACT Trial - mHealth Strategies for the Pediatric to Adult HIV Care Transition (mPACT)

Transition From Pediatric to Adult HIV Care

Kenya
Société des Produits Nestlé (SPN)

Completed

A Study to Investigate the Effect of Protein in Infant Formula on Insulin Response in Adults (IDEFIX)

To Compare the Metabolic Effects of Different Infant Milks
Harvard School of Public Health (HSPH)
Elton John AIDS Foundation; Management and Development for Health, Tanzania; Comic...

Completed

Trial to Improve Access to PMTCT Services and Reduce HIV Transmission From Mother to Child (FS)

Pregnancy | Mother-to-child Transmission of HIV

Tanzania
Hospices Civils de Lyon

Active, not recruiting

Neuropathy and Anti-GFAP Antibodies (Neuro-GFAP)

Neurological Diseases or Conditions | Neurological Diseases Associated to Anti GFAP Antibodies

France
DeviceFarm, Inc.
Symbio, LLC; Center for Dermatology Clinical Research, Inc.

Completed

Early Feasibility Study to Evaluate the Efficacy and Safety of the RenewalNail™ Plasma Treatment System in Patients With Mild to Moderate Onychomycosis (Fungal Nail)

Onychomycosis Due to Trichophyton Rubrum | Onychomycosis Due to Trichophyton Mentagrophytes

United States
Assistance Publique - Hôpitaux de Paris

Completed

Evaluation of the TRANSEND Program (EVATRANSEND)

Pediatric Patient Transfer to Adult Service:Transition Program

France
Odense University Hospital
Fredericia Hosptial

Completed

The Effects of Spironolactone on Calcineurin Inhibitor Induced Nephrotoxicity (SPIREN)

Disorder Related to Renal Transplantation

Denmark
QRxPharma Inc.

Completed

Extension Study to Evaluate the Safety of Q8003 in Patients With Acute Moderate to Severe Pain

Acute Moderate to Severe Pain

United States
Eloxx Pharmaceuticals, Inc.
SGS Life Sciences, a division of SGS Belgium NV

Completed

Phase 1 Study of ELX-02 in Healthy Adults

Genetic Disease | Nonsense Mutation

Belgium
Children's Mercy Hospital Kansas City

Completed

Genomic Sequencing in Acutely Ill Neonates (NSIGHT)

Genetic Disease | Diseases/Diagnoses

United States
Royal Medical Services, Jordanian Armed Forces

Completed

Surgical Management of Placenta Accreta

To Publish Our Experience in the Surgical Management to Placenta Accreta Cases and the Maternal Outcome
Eloxx Pharmaceuticals, Inc.
SGS Life Sciences, a division of SGS Belgium NV

Completed

Phase 1 Study of ELX-02 in Healthy Adult Subjects

Genetic Disease | Nonsense Mutation

Belgium
Assistance Publique Hopitaux De Marseille

Unknown

Predisposition to Infectious Endocarditis

Infective Endocarditis

France
University Hospital, Bordeaux

Not yet recruiting

Prospective Cohort Study of Neurogenetic Diseases (CNGD)

Nervous System Diseases | Genetic Disease
Liggins Institute

Recruiting

Newborn Genomics Programme

Genetic Disease | Newborn Morbidity

New Zealand
Nan Shen
Novartis

Not yet recruiting

Disease and Biomarker Profiling of Chinese Lupus Nephritis

Characterize the Molecular Profile of Lupus Nephritis(LN) Patients to Understand Themechanism(s)Contributing to Patient Responsiveness to Soc | Integrated Analysis of LN Patient Molecular Profiling and Clinical Annotations to Understand LNdisease Heterogeneity for Disease Endotype | Validate the Association of the Candidate Biomarker Panel Proposed in Table 3-1 With LN Diseasemonitoring
Abbott

Completed

A Double-blind, Randomized, Multicenter, Cross-over Study to Compare the Effect of Creon N and Creon® on Fat Digestion in Subjects ≥ 12 Years of Age With Pancreatic Exocrine Insufficiency Due to Cystic Fibrosis

Pancreatic Exocrine Insufficiency Due to Cystic Fibrosis

Hungary, Spain
Ekso Bionics

Completed

Exoskeleton Treatment of Deconditioning Due to Limited Ambulation Caused by Illness or Injury

Debility Due to Disease

United States
Rigshospitalet, Denmark
Copenhagen University Hospital, Denmark

Recruiting

Rehabilitation for Survivors of Out-of-hospital Cardiac Arrest

Heart Arrest | Rehabilitation | Cardiac Arrest | Cardiac Rehabilitation | Cardiopulmonary Resuscitation | Recovery of Function | Return to Work | Return-to-work

Denmark
Novo Nordisk A/S

Completed

To Quantify the Range of Main Psychosocial Factors Affecting Patients and Caregivers in Their Daily Lives (HERO)

Congenital Bleeding Disorder | Haemophilia A With Inhibitors | Haemophilia B With Inhibitors | Haemophilia A | Haemophilia B | Relatives to/Carers of Patients

Brazil
Massachusetts General Hospital
n-Lorem Foundation

Not yet recruiting

Single Participant Study of an Experimental ASO Treatment for TUBB4A-related Leukodystrophy

Genetic Disease
Neuromed IRCCS

Recruiting

Implementation of Molecular Diagnostic Pathways

Genetic Disease

Italy
University of Pennsylvania
Fox Chase Cancer Center; Columbia University; Thomas Jefferson University

Enrolling by invitation

Penn Medicine Biobank Return of Results Program (ROR)

Cardiovascular Diseases | Cancer | Genetic Disease

United States
Novo Nordisk A/S

Completed

Survey Evaluating the Psychosocial Effects of Living With Haemophilia (HERO)

Congenital Bleeding Disorder | Haemophilia A With Inhibitors | Haemophilia B With Inhibitors | Haemophilia A | Haemophilia B | Relatives to/Carers of Patients

Spain, Canada, United Kingdom
Charite University, Berlin, Germany

Unknown

Medication Adherence and "True" Resistance in Patients With Resistant Hypertension

Hypertensive Disease | Hypertension, Resistant to Conventional Therapy

Germany
Mayo Clinic

Terminated

Prophylactic Ethanol Lock Therapy (ELT) in Patients on Home Parenteral Nutrition (ELT)

Catheter-related Bloodstream Infection (CRBSI) Nos | Bloodstream Infection Due to Central Venous Catheter | Bloodstream Infection Due to Hickman Catheter

United States
University of California, Irvine

Recruiting

Acupuncture Therapy and Hypertension

Mild to Moderate Hypertension

United States
Organon and Co

Completed

MK0954A-264 Filter Study (0954A-264)(COMPLETED)

Mild to Severe Hypertension
Charles University, Czech Republic
University Hospital Olomouc; General University Hospital, Prague; Cardiocenter...

Terminated

Renal Denervation in Refractory Hypertension (PRAGUE-15)

Hypertension | Resistant to Conventional Therapy

Czechia
University of Washington
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Individualized Response to Vitamin D Treatment Study (INVITE)

Characteristics That Modify the Response to Cholecalciferol Treatment

United States
University of Washington
National Institute of Mental Health (NIMH)

Enrolling by invitation

Impact of Male Provider Phone Calls to Increase Men's Clinic Linkage After HIVST

PrEP | HIV | PMTCT | Linkage to Care | ART Adherence

Uganda
University of Washington
National Institute of Mental Health (NIMH); University of North Carolina, Chapel... and other collaborators

Completed

HIV Self Testing of Male Partners of Women in PMTCT

PrEP | HIV | PMTCT | Linkage to Care | ART Adherence

Uganda
AllerQuest LLC

Completed

Evaluation of Skin Testing Reagents for Penicillin Allergy

History of IgE Dependent Reaction to a Penicillin Product

United States
University of Oxford
University of Michigan; University of Southern California; Chelsea and Westminster... and other collaborators

Recruiting

Rescue for Emergency Surgery Patients Observed to uNdergo Acute Deterioration (RESPOND)

Emergencies | Failure to Rescue

United Kingdom
University Hospital, Ghent

Completed

Genetic Screening and Assisted Oocyte Activation in Couples With Diminished/Aberrant Embryonic Development. (AOA)

Genetic Disease | Embryo | Embryo Disorder

Belgium
ReCor Medical, Inc.

Active, not recruiting

RADIANCE Continued Access Protocol (RADIANCE CAP)

Cardiovascular Diseases | Vascular Diseases | Hypertension | Hypertension, Resistant to Conventional Therapy

United States
E-Star BioTech, LLC
Mayo Clinic; PPD

Not yet recruiting

To Evaluate the Safety and Efficacy of MANP in Subjects With Difficult to Control/ Resistant Hypertension

Difficult to Control Hypertension
Novartis Pharmaceuticals

Completed

Evaluation of Drug-drug Interaction Between LCZ696 and Sildenafil in Subjects With Mild to Moderate Hypertension

Mild to Moderate Hypertension

Germany
Associate Professor Helen Marshall
Merck Sharp & Dohme LLC

Unknown

Impact of Rotavirus Vaccine Introduction for South Australian Children

Gastroenteritis | Viral Gastroenteritis Due to Rotavirus

Australia
Mahidol University

Unknown

Cervical Ripening Before Endometrial Biopsy in Abnormal Uterine Bleeding Using Sublingual Misoprostol

Abnormal Uterine Bleeding Unrelated to Menstrual Cycle

Thailand
Columbia University

Recruiting

Targeted Fortification of Donor Breast Milk in Preterm Infants

Growth Failure | Growth Retardation | Prematurity; Extreme | Infant Nutrition Disorders | Failure to Thrive in Newborn

United States

Clinical Trials on Genetic Predisposition to Disease

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Netherlands

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations