Clinical Trials on Genomic Instability in Japan

Total 470 results

Novartis Pharmaceuticals

Recruiting

Study of HRO761 Alone or in Combination in Cancer Patients With Specific DNA Alterations Called Microsatellite Instability or Mismatch Repair Deficiency.

MSIhi or dMMR Advanced Unresectable or Metastatic Solid Tumors, Including Colorectal Cancers

Japan, Italy, Spain, Singapore, Belgium, Germany, Korea, Republic of, Sweden, Taiwan, France, Israel, Norway, United States
Bristol-Myers Squibb
Ono Pharmaceutical Co. Ltd

Recruiting

A Study of Nivolumab, Nivolumab Plus Ipilimumab, or Investigator's Choice Chemotherapy for the Treatment of Participants With Deficient Mismatch Repair (dMMR)/Microsatellite Instability High (MSI-H) Metastatic Colorectal Cancer (mCRC) (CheckMate 8HW)

Metastatic Colorectal Cancer

United States, Belgium, China, Canada, Denmark, France, Norway, Romania, Spain, United Kingdom, Austria, Brazil, Germany, Netherlands, Argentina, Czechia, Ireland, Italy, Turkey, Chile, Greece, Puerto Rico, Australia, Japan
Bayer

Completed

A Study to Learn More About What Japanese Patients With Solid Tumors Think About Taking Medicine That is Based on Their Genetic Information

Cancer Genomic Profiling

Japan
University of Jazan

Completed

Effects of Pilates Exercises on Core Stability After Recovery From COVID -19

Covid19 | Pilates, Core Stability

Saudi Arabia
Novo Nordisk A/S

Completed

A Survey Collecting Data on Adult Height in Patients With Achondroplasia Treated With Somatropin

Achondroplasia | Genetic Disorder

Japan
Novo Nordisk A/S

Completed

Special Survey for Long Term Application

Achondroplasia | Genetic Disorder

Japan
Daiichi Sankyo Co., Ltd.

Terminated

Phase I Study of DS-2741a in Healthy Volunteers and Participants With Atopic Dermatitis

Atopic Dermatitis

Japan
Kyowa Kirin Co., Ltd.

Terminated

Study of KHK 4323 in Healthy Volunteers and Subjects With Atopic Dermatitis

Atopic Dermatitis

Japan
Kyowa Kirin Co., Ltd.

Completed

A Phase 1 Study of KHK4083 in Subjects With Atopic Dermatitis

Dermatitis, Atopic

Japan
GlaxoSmithKline

Completed

Skin Irritation Study of GSK2894512 Cream

Dermatitis, Atopic

Japan
Pfizer

Recruiting

A Study to Learn About the Study Medicine (CIBINQO) in People With Atopic Dermatitis.

Atopic Dermatitis

Japan
Otsuka Pharmaceutical Co., Ltd.

Completed

Long-term Trial of OPA-15406 Ointment in Adult and Pediatric Patients With Atopic Dermatitis

Atopic Dermatitis

Japan
Otsuka Pharmaceutical Co., Ltd.

Completed

Comparison Trial of OPA-15406 Ointment in Pediatric Patients With Atopic Dermatitis

Atopic Dermatitis

Japan
Mitsubishi Tanabe Pharma Corporation

Completed

A Confirmatory Study of TAU-284 in Pediatric Patients With Atopic Dermatitis

Dermatitis | Atopic

Japan
Dermavant Sciences GmbH

Completed

A Study of E6005 in Japanese Patients With Atopic Dermatitis

Atopic Dermatitis

Japan
Otsuka Pharmaceutical Co., Ltd.

Completed

Comparison Trial of OPA-15406 Ointment in Adult Patients With Atopic DermatitisSyndrome

Atopic Dermatitis

Japan
Taiho Pharmaceutical Co., Ltd.

Completed

A Study of TAS-205 for Duchenne Muscular Dystrophy

Duchenne Muscular Dystrophy

Japan
Otsuka Pharmaceutical Co., Ltd.

Completed

A Long-term Trial of OPA-15406 in Infants With Atopic Dermatitis

Atopic Dermatitis (AD)

Japan
Novartis

Completed

Extension Study of Pimecrolimus Cream in Pediatric Patients With Atopic Dermatitis

Atopic Dermatitis

Japan
LEO Pharma
Bayer

Completed

An Observational Study Investigating the Treatment Satisfaction of Atopic Dermatitis Patients Who Have Switched to Ointment (W/O Emulsion) Formulation of Very Strong Class Topical Corticosteroids (Ointment TS-AD)

Dermatitis, Atopic

Japan
Kyowa Kirin Co., Ltd.

Completed

Phase 2 Study of KHK4577

Atopic Dermatitis

Japan
Novartis

Completed

Extension Study to Assess Safety and Efficacy of Pimecrolimus in Adult Patients With Atopic Dermatitis

Atopic Dermatitis

Japan
Bayer

Completed

HPA Axis Study in Japanese Adults

Eczema | Atopic Dermatitis

Japan
National Center of Neurology and Psychiatry, Japan
Nippon Shinyaku Co., Ltd.

Completed

Exploratory Study of NS-065/NCNP-01 in DMD

Duchenne Muscular Dystrophy

Japan
National Center of Neurology and Psychiatry, Japan
Nippon Shinyaku Co., Ltd.

Completed

Exploratory Study of NS-089/NCNP-02 in DMD

Duchenne Muscular Dystrophy

Japan
Pfizer

Completed

A Study of Crisaborole Ointment 2% in Adult Japanese Healthy Subjects and Adult Japanese Subjects With Mild To Moderate Atopic Dermatitis

Healthy | Atopic Dermatitis

Japan
Novo Nordisk A/S

Enrolling by invitation

Post-Marketing Surveillance (All Case Surveillance) on Treatment With Alhemo® in Patients With Haemophilia A or Haemophilia B With Inhibitors

Haemophilia A | Haemophilia B

Japan
Nippon Shinyaku Co., Ltd.

Active, not recruiting

Extension Study of NS-089/NCNP-02 in DMD

Duchenne Muscular Dystrophy (DMD)

Japan
Suzuka Hospital
Nagoya University

Unknown

The Preventive Efficacy of Carvedilol on Cardiac Dysfunction in Duchenne Muscular Dystrophy

Cardiomyopathies | Duchenne Muscular Dystrophy

Japan
Takeda

Recruiting

Specified Drug-Use Survey of Leuprorelin Acetate Injection Kit 11.25 mg "All-Case Investigation: Spinal and Bulbar Muscular Atrophy (SBMA)"

Spinal and Bulbar Muscular Atrophy

Japan
Novo Nordisk A/S

Completed

Non-Interventional Study of NovoSeven® Used in Patients With Haemophilia A and B With Inhibitors When Undergoing Surgery

Congenital Bleeding Disorder | Haemophilia A With Inhibitors | Haemophilia B With Inhibitors

Japan
AbbVie

Recruiting

A Study to Assess Change in Disease Activity in Adolescents and Adults With Moderate to Severe Prurigo-type Atopic Dermatitis in Japan Who Are Treated With Oral Upadacitinib (ADMIRE)

Atopic Dermatitis

Japan
Pfizer

Completed

BeneFIX Drug Use Results Survey [All-Case Surveillance]

Hemophilia B

Japan
Janssen Pharmaceutical K.K.

Completed

An Observational Study of Japanese Participants With X-linked Retinitis Pigmentosa

X-Linked Retinitis Pigmentosa

Japan
Novo Nordisk A/S

Completed

Non-Interventional Study of NovoSeven® Used in Patients With Haemophilia A and B With Inhibitors Under Normal Clinical Practice

Congenital Bleeding Disorder | Haemophilia A With Inhibitors | Haemophilia B With Inhibitors

Japan
Novo Nordisk A/S

Completed

Non-Interventional Study of NovoSeven® Used as On-demand Treatment of Bleeds in Patients With Haemophilia A and B With Inhibitors

Congenital Bleeding Disorder | Haemophilia A With Inhibitors | Haemophilia B With Inhibitors

Japan
Novo Nordisk A/S

Completed

Non-interventional Study of Patients Using Norditropin® for Growth Hormone Deficiency or Turner Syndrome (NordiPAD)

Turner Syndrome | Growth Hormone Disorder | Growth Hormone Deficiency in Children | Genetic Disorder

Japan
GlaxoSmithKline

Completed

A Study to Test the Possibility of Cross Reaction Induced by the Idursulfase Drug to GSK2788723

Mucopolysaccharidosis II

Japan
Genzyme, a Sanofi Company

Completed

A Long Term Safety and Efficacy Study of Fabrazyme Replacement Therapy in Japanese Patients With Fabry Disease.

Fabry Disease

Japan
Astellas Pharma Inc

Completed

Development of Visual Function Evaluation Method (2)

Retinitis Pigmentosa

Japan
Okayama University
Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan

Completed

Transcoronary Infusion of Cardiac Progenitor Cells in Pediatric Dilated Cardiomyopathy (TICAP-DCM)

Dilated Cardiomyopathy

Japan
Takeda

Completed

A Study of TAK-660 in Surgical Procedures for People With Hemophilia A.

Hemophilia A

Japan
Novo Nordisk A/S

Completed

Observational Study of the Safety and Efficacy of Norditropin® in Patients With SGA (Small for Gestational Age) Short Stature That Are Still Growing

Foetal Growth Problem | Small for Gestational Age

Japan
Janssen Pharmaceutical K.K.

Recruiting

A Study of AAV5-hRKp.RPGR for the Treatment of Japanese Participants With X-linked Retinitis Pigmentosa

X-Linked Retinitis Pigmentosa

Japan
Kissei Pharmaceutical Co., Ltd.

Completed

A Study of KPS-0373 in Patients With Spinocerebellar Degeneration (SCD)

Spinocerebellar Degeneration

Japan
Nagoya University

Completed

BiPAP for Cardiomyopathy With Central Sleep Apnea

Dilated Cardiomyopathy

Japan
Otsuka Pharmaceutical Co., Ltd.

Completed

Study of OPA-15406 Ointment in Patients With Atopic Dermatitis

Atopic Dermatitis

Japan
Taiho Pharmaceutical Co., Ltd.

Recruiting

A Phase 3 Study of TAS-205 in Patients With Duchenne Muscular Dystrophy（REACH-DMD）

Duchenne Muscular Dystrophy

Japan
Takeda

Recruiting

A Survey of Susoctocog Alfa (Genetical Recombination) in Participants With Acquired Haemophilia A

Acquired Hemophilia A

Japan
Astellas Pharma Inc

Completed

Development of Visual Function Evaluation Method

Retinitis Pigmentosa

Japan

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