Clinical Trials on Germ Cell Neoplasms

Total 109711 results

Centre Hospitalier Universitaire de Nīmes

Completed

Circulating Tumor Cells and Melanoma: Comparing the EPISPOT and CellSearch Techniques

Metastatic Melanoma

France
Queen Mary University of London

Completed

Bleomycin, Etoposide, and Cisplatin in Treating Patients With Metastatic Germ Cell Cancer of the Testicles

Testicular Germ Cell Tumor | Drug/Agent Toxicity by Tissue/Organ

United Kingdom
National Cancer Institute (NCI)

Completed

A Case-Control Study of Testicular Germ Cell Tumors Among U.S. Military Servicemen

Testicular Cancer

United States
Nasser Hanna

Completed

Study of the Hypomethylating Drug Guadecitabine (SGI-110) Plus Cisplatin in Relapsed Refractory Germ Cell Tumors

Testis Cancer | Testicular Cancer | Germ Cell Tumor

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Neoadjuvant Chemotherapy With or Without Second-Look Surgery Followed by Radiation Therapy With or Without Peripheral Stem Cell Transplantation in Treating Patients With Intracranial Germ Cell Tumors

Brain Tumor | Central Nervous System Tumors | Childhood Germ Cell Tumor

United States, Canada, Australia, Switzerland, New Zealand
European Institute of Oncology

Recruiting

Definition of a Multiparametric Prognostic and Predictive System of Classification of NET G3 Patients (TAPIOCA)

Neuroendocrine Neoplasm

Italy
Biotheus Inc.

Recruiting

A Study of PM8002 Injection in Combination With Chemotherapy in Patients With NEN

Neuroendocrine Neoplasm

China
National Cancer Institute (NCI)

Active, not recruiting

Testing the Addition of An Anti-cancer Drug, M3814 (Peposertib), to the Usual Radiation-Based Treatment (Lutetium Lu 177 Dotatate) for Pancreatic Neuroendocrine Tumors

Neuroendocrine Neoplasm

United States
Jagiellonian University
Medical University Innsbruck; University Medical Centre Ljubljana; University... and other collaborators

Completed

Novel 99mTc-labeled Somatostatin Antaginosts in the Diagnostic Algotithm of Neuroendocrine Neoplasms (TECANT)

Neuroendocrine Tumors

Austria, Poland, Slovenia
Xiangya Hospital of Central South University

Unknown

A Study of 18F-AlF-NOTA-octreotide PET/CT for Imaging Neuroendocrine Neoplasms

Neuroendocrine Neoplasm

China
National Cancer Center, China

Recruiting

Lateral Pelvic Lymph Node Dissection for Rectal Neuroendocrine Neoplasms Undergoing Laparoscopic Total Mesenteric Excision

Rectal Neuroendocrine Neoplasm

China
Peking University

Recruiting

Sintilimab Combined With IBI310 and Surufatinib for the Treatment of G3-NET and NEC

Neuroendocrine Neoplasm

China
Fudan University
D1 Medical Technology (Shanghai) Co., Ltd, China

Recruiting

Single-cell Sequencing and Establishment of Models in Neuroendocrine Neoplasm

Neuroendocrine Neoplasm

China
Tine Gregersen, MD

Recruiting

Dosimetry Based PRRT Versus Standard Dose PRRT With Lu-177-DOTATOC in NEN Patients (DOBATOC)

Neuroendocrine Neoplasm

Denmark
Memorial Sloan Kettering Cancer Center

Completed

Combination Chemotherapy Followed by Bone Marrow Transplantation in Treating Patients With Rare Cancer

Sarcoma | Lymphoma | Kidney Cancer | Testicular Germ Cell Tumor | Head and Neck Cancer | Ovarian Cancer | Neuroblastoma | Retinoblastoma | Liver Cancer | Extragonadal Germ Cell Tumor | Childhood Germ Cell Tumor

United States
West Virginia University
West Virginia Clinical and Translational Science Institute

Terminated

Carvedilol With Chemotherapy in Second Line Glioblastoma and Response of Circulating Tumor Cells

Glioblastoma | Glioblastoma Multiforme

United States
West Virginia University
NovoCure Ltd.; West Virginia Clinical and Translational Science Institute

Withdrawn

Anti-Cancer Effects of Carvedilol With Standard Treatment in Glioblastoma and Response of Peripheral Glioma Circulating Tumor Cells

Glioblastoma | Glioblastoma Multiforme

United States
Faculdade de Medicina de Catanduva

Completed

Anterior Mediastinum Teratoma: A Case Report

Teratoma

Brazil
Xian-Jun Yu

Not yet recruiting

Neuroendocrine Neoplasm Based on Multi-omics Integrated Analysis

Neuroendocrine Neoplasm

China
City of Hope Medical Center
National Cancer Institute (NCI)

Withdrawn

Palliative Care in Improving Quality of Life and Symptoms in Patients With Stage III-IV Pancreatic or Ovarian Cancer

Recurrent Pancreatic Cancer | Stage III Pancreatic Cancer | Stage IV Pancreatic Cancer | Stage IV Ovarian Epithelial Cancer | Stage IV Ovarian Germ Cell Tumor | Recurrent Ovarian Epithelial Cancer | Recurrent Ovarian Germ Cell Tumor | Stage IIIA Ovarian Germ Cell Tumor | Stage IIIB Ovarian Germ Cell... and other conditions

United States
National University of Singapore

Recruiting

Adolescent and Young Adult Cancer Patients: Cognitive Toxicity on Survivorship (ACTS)

Lymphoma | Breast Cancer | Cognitive Impairment | Germ Cell Tumor

Singapore
University of Southern California
Sanofi

Completed

Study of Gemcitabine, Oxaliplatin, and Paclitaxel in Patients With Refractory Germ Cell Carcinoma

Testicular Cancer | Germ Cell Neoplasm

United States
National Cancer Institute (NCI)

Withdrawn

Aerosolized Azacytidine as Epigenetic Priming for Bintrafusp Alfa-Mediated Immune Checkpoint Blockade in Patients With Unresectable Pulmonary Metastases From Sarcomas, Germ Cell Tumors, or Epithelial Malignancies

Pulmonary Metastases | Germ Cell Tumors | Sarcomas | Melanomas | Epithelial Malignancies (Excluding Lung and Renal Cell Carcinomas)

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Withdrawn

StrataXRT in Preventing Radiation Dermatitis in Pediatric Patients Undergoing Radiation Therapy to the Brain or Spinal Cord

Glioma | Ependymoma | Medulloblastoma | Pineoblastoma | Central Nervous System Sarcoma | Primary Central Nervous System Neoplasm | Malignant Intracranial Germ Cell Tumor

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Studying Genes in Samples From Younger Patients With Ovarian or Testicular Sex Cord Stromal Tumors

Ovarian Cancer | Leydig Cell Tumor | Childhood Germ Cell Tumor
Novartis Pharmaceuticals

Completed

Safety and Efficacy of RAD001 in Chinese Patients With Advanced Pulmonary Neuroendocrine Tumor (\MACS1304)

Lung Neuroendocrine Neoplasm

China
HiFiBiO Therapeutics

Recruiting

A Study of HFB200301 as a Single Agent and in Combination With Tislelizumab in Adult Patients With Advanced Solid Tumors

Melanoma | Sarcoma | Renal Cell Carcinoma | Cervical Cancer | Testicular Germ Cell Tumor | Gastric Cancer | Non Small Cell Lung Cancer | Mesothelioma | Head and Neck Squamous Cell Carcinoma

United States, Spain
Boehringer Ingelheim

Recruiting

DAREON™-7: A Study to Test How Well Different Doses of BI 764532 in Addition to Chemotherapy Are Tolerated by People With Advanced Neuroendocrine Cancers

Neuroendocrine Neoplasms

United States, Spain, Germany, Japan
City of Hope Medical Center
National Cancer Institute (NCI)

Terminated

Dasatinib, Ifosfamide, Carboplatin, and Etoposide in Treating Young Patients With Metastatic or Recurrent Malignant Solid Tumors

Sarcoma | Lymphoma | Kidney Cancer | Unspecified Childhood Solid Tumor, Protocol Specific | Testicular Germ Cell Tumor | Ovarian Cancer | Brain and Central Nervous System Tumors | Neuroblastoma | Liver Cancer | Extragonadal Germ Cell Tumor | Childhood Germ Cell Tumor

United States
Johannes Gutenberg University Mainz
Ipsen; Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA...

Active, not recruiting

Cabozantinib in Combination With Avelumab in Patients Refractory to Standard Chemotherapy With Advanced Neuroendocrine Neoplasias G3 (NEN G3)

Cancer

Germany
King's College Hospital NHS Trust
Ampersand Health Ltd; Neuroendocrine Cancer UK

Recruiting

Mobile Application to Collect PRO Data in NET Patients

Neuroendocrine Neoplasms (Tumours)

United Kingdom
St. Jude Children's Research Hospital
National Cancer Institute (NCI)

Completed

Memantine for Prevention of Cognitive Late Effects in Pediatric Patients Receiving Cranial Radiation Therapy for Localized Brain Tumors

Ependymoma | Craniopharyngioma | Germ Cell Tumor | Glioma of Brain

United States
The First People's Hospital of Changzhou

Not yet recruiting

Effect of Cytokine-induced Killer Cells for Stage I-II Malignant Gliomas

Cytokine-Induced Killer Cells | Milignant Gliomas
M.D. Anderson Cancer Center

Active, not recruiting

Proton Beam Therapy for Chordoma Patients

Chordoma

United States
University Hospital Heidelberg

Completed

CDK4/6 Inhibition in Locally Advanced/Metastatic Chordoma (NCT-PMO-1601)

Chordoma

Germany
Dana-Farber Cancer Institute
National Cancer Institute (NCI)

Completed

High-dose ICE With Amifostine

Sarcoma | Kidney Cancer | Testicular Germ Cell Tumor | Head and Neck Cancer | Ovarian Cancer | Lung Cancer | Brain and Central Nervous System Tumors | Unspecified Adult Solid Tumor, Protocol Specific | Bladder Cancer | Extragonadal Germ Cell Tumor | Carcinoma of Unknown Primary

United States
Bavarian Nordic

Completed

BN Brachyury and Radiation in Chordoma

Chordoma

United States
Centre Hospitalier Universitaire de Saint Etienne

Completed

Immunohistochemical Study of Chordomas to Improve Their Diagnosis and Prognosis Care (CHORDOMES)

Chordoma

France
NantCell, Inc.
National Cancer Institute (NCI)

Unknown

QUILT-3.011 Phase 2 Yeast-Brachyury Vaccine Chordoma

Chordoma

United States
Centre Oscar Lambret
Canceropôle Nord Ouest; Groupement Interrégional de Recherche Clinique et d...

Recruiting

Assessment of Compliance With Monitoring Conducted by a Physician in Person or by a Nurse in Remote Monitoring (SUR-CAN)

Glioma | Gastrointestinal Stromal Tumors | Neuroendocrine Tumors | Adenocarcinoma, Clear Cell | Carcinoma, Small Cell | Ovarian Germ Cell Tumor | Stage I Testicular Seminoma | Stage I Testicular Nonseminomatous Germ Cell Tumor | Borderline Ovarian Tumor | Sex Cord-Stromal Tumor | Mucinous Adenocarcinoma of... and other conditions

France
Beijing Tiantan Hospital

Recruiting

The Efficacy of WVI in Patients With Localized Basal Ganglia Intracranial Germ Cell Tumors

Intracranial Germ Cell CNS Tumor, Childhood

China
National Cancer Institute (NCI)

Recruiting

Children and Adults With Chordoma

Chordoma

United States
Italian Sarcoma Group

Recruiting

Sacral Chordoma: Surgery Versus Definitive Radiation Therapy in Primary Localized Disease (SACRO)

Chordoma

Italy, Spain, Netherlands, Austria, Germany, Hungary, Japan, Norway, Poland, United Kingdom
Massachusetts General Hospital

Active, not recruiting

Nilotinib With Radiation for High Risk Chordoma

Chordoma

United States
Saint John's Cancer Institute
Eli Lilly and Company; Chordoma Foundation

Completed

Pemetrexed for the Treatment of Chordoma

Chordoma

United States
Leiden University Medical Center
Boehringer Ingelheim; Chordoma Foundation

Active, not recruiting

Afatinib in Locally Advanced and Metastatic Chordoma

Chordoma

United Kingdom, Netherlands, Italy
Shanghai 10th People's Hospital

Completed

The Differences Between Gonadal and Extra-gonadal Malignant Teratomas

SEER Database
National Cancer Institute (NCI)

Completed

Chordoma Family Study

Chordoma

United States
Novartis Pharmaceuticals

Completed

Efficacy and Safety of Imatinib in Chordoma

Chordoma

Switzerland, Italy
University of Malaga

Suspended

Effectiveness of an Individualized Program of Muscular Strength and Endurance Program for Improving Germ Cell Cancer (EFICATEST)

Testicular Germ Cell Cancer

Spain

Clinical Trials on Germ Cell Neoplasms

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Medical Conditions

Drug Interventions

CROs by country

CROs in Mauritius

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Rare Diseases

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