Clinical Trials on Germline Mutation Carrier
Total 3003 results
-
University of California, Los AngelesBoston Children's Hospital; Duke University; Children's Hospital Medical Center...RecruitingBohring-Opitz Syndrome | ASXL1 Gene Mutation | Shashi-Pena Syndrome | ASXL2 Gene Mutation | Bainbridge-Ropers Syndrome | ASXL3 Gene MutationUnited States
-
Sidney Kimmel Comprehensive Cancer Center at Johns...Merck Sharp & Dohme LLCActive, not recruitingHigh Tumor Mutation Burden | High TMB (Tumor Mutation Burden) | MSS (Microsatellite Stable)United States
-
xCuresCancer CommonsAvailableExpanded Access to Ulixertinib (BVD-523) in Patients With Advanced MAPK Pathway-Altered MalignanciesMelanoma | Head and Neck Cancer | Glioblastoma | Hepatocellular Carcinoma | Gastric Cancer | Colorectal Cancer | Pancreatic Cancer | Esophageal Cancer | Small Bowel Cancer | Ovarian Cancer | Non Small Cell Lung Cancer | Cholangiocarcinoma | Bladder Cancer | Thyroid Cancer | ERK Mutation | MAPK Gene Mutation | KRAS Activating... and other conditionsUnited States
-
Iambic Therapeutics, IncRecruiting
-
Affiliated Hospital to Academy of Military Medical...RecruitingEndoscopy | Mitochondrial DNA MutationChina
-
The University of Hong KongUnknownAML | FLT3-ITD MutationHong Kong
-
Boehringer IngelheimActive, not recruitingSolid Tumors, KRAS MutationSpain, United Kingdom, United States, Belgium
-
iOMEDICO AGRoche Pharma AGActive, not recruitingNTRK Family Gene MutationSwitzerland, Germany
-
Shanghai Jiatan Pharmatech Co., LtdCompletedPIK3CA Mutation-Related TumorsChina
-
AZ-VUBUnknownCancers Harbouring an EGFR Mutation, (Excluding Non-squamous Non- Small Cell Lung Cancer, a Registered Indication), a HER2 Mutation or a HER3 MutationBelgium
-
Okayama UniversityMerck Sharp & Dohme LLCRecruitingBreast Cancer | Breast Neoplasms | Triple Negative Breast Cancer | Triple Negative Breast Neoplasms | BRCA1 Mutation | BRCA2 Mutation | BRCA Mutation | BRCA-Associated Breast CarcinomaJapan
-
Korean Cancer Study GroupUnknownMetastatic Solid Tumor | DDR Gene MutationKorea, Republic of
-
Irina A AnselmNo longer availableCitrate Transporter Deficiency | SLC13A5 Gene MutationUnited States
-
ABM Therapeutics CorporationRecruitingAdvanced Solid Tumor | RAS Mutation | NF1 Mutation | RAF MutationUnited States
-
University of ChicagoRecruitingMyeloproliferative Neoplasm | Blood Cancer | IDH2 Gene Mutation | IDH1 Mutation | IDH MutationUnited States
-
Massachusetts General HospitalAgios Pharmaceuticals, Inc.CompletedIDH1 Mutation Myeloid NeoplasmsUnited States
-
NYU Langone HealthWithdrawnBreast Cancer | BRCA1 Mutation | BRCA2 MutationUnited States
-
Guangdong Provincial People's HospitalShanghai Junshi Bioscience Co., Ltd.RecruitingNon-Small Cell Lung Cancer | BRAF V600 Mutation | MET Amplification | MET Exon 14 Skipping Mutation | RET Driver Mutation | Erb-B2 Receptor Tyrosine Kinase Exon 20 MutationChina
-
M.D. Anderson Cancer CenterNational Cancer Institute (NCI)Active, not recruitingBRCA1 Gene Mutation | BRCA2 Gene Mutation | Metastatic Malignant Neoplasm | Advanced Malignant Neoplasm | Recurrent Malignant Neoplasm | Refractory Malignant Neoplasm | PALB2 Gene Mutation | ATM Gene MutationUnited States
-
Boehringer IngelheimRecruitingSolid Tumor, KRAS MutationUnited States, Taiwan, Japan
-
Massachusetts General HospitalCompletedBreast Cancer | BRCA1 Mutation | BRCA2 MutationUnited States
-
Vanderbilt University Medical CenterRecruitingIdiopathic Pulmonary Arterial Hypertension | Heritable Pulmonary Arterial Hypertension | Unaffected Mutation Carriers: Healthy Participants With a Known BMPR2 Gene Mutation and Normal Pulmonary Pressure and RV Function on Echo | Healthy Individuals With no Cardiopulmonary DiseaseUnited States
-
University Health Network, TorontoBayer; AstraZeneca; Amgen; AnHeart Therapeutics Inc.; Applied Health Research Centre and other collaboratorsRecruitingCancer | Malignancies Multiple | Malignant Solid Tumor | Cancer, Therapy-Related | Molecular Sequence Variation | Genetic Alteration | Gene Fusion | Receptor Tyrosine Kinase Gene Mutation | RTK Family Gene Mutation | Ras (Kras or Nras) Gene MutationCanada
-
Prisma Health-UpstateIpsenRecruitingSolid Tumor | ARID1A Gene MutationUnited States
-
Shandong UniversityFudan University; Chinese Nutrition SocietySuspended
-
Boehringer IngelheimActive, not recruitingSolid Tumors, KRAS Mutation; SOS1United States, Netherlands, Germany
-
Royal Marsden NHS Foundation TrustCompletedMRI | BRCA1 Mutation | BRCA2 Mutation | MammographyUnited Kingdom
-
Shirley Ryan AbilityLabUniversity of AlbertaRecruitingAmputation | Amputation; Traumatic, Hand | Amputation, Traumatic | Amputation; Traumatic, LimbUnited States
-
National Heart, Lung, and Blood Institute (NHLBI)CompletedMitochondrial Disorders | Li-Fraumeni Syndrome | Carriers of p53 MutationUnited States
-
Liberating Technologies, Inc.Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaboratorsCompletedAmputation | Prosthesis User | Amputation; Traumatic, Hand | Amputation, CongenitalUnited States
-
Istituto Clinico HumanitasCelgeneUnknownAcute Myeloid Leukemia | IDH2 Gene Mutation | IDH1 Gene MutationItaly
-
Centre Hospitalier Universitaire de BesanconCompletedBreast Cancer | BRCA1 Mutation | BRCA2 MutationFrance
-
Georgetown UniversityImmune System Key LtdRecruitingSolid Tumor | KRAS Mutation-Related TumorsUnited States
-
Suzhou Zelgen Biopharmaceuticals Co.,LtdRecruitingSolid Tumor | KRAS Mutation-Related TumorsChina
-
Ruijin HospitalRecruitingP53 Mutation | Myeloid Malignancy | MDS | AmlChina
-
Blueprint Medicines CorporationCompletedSystemic Mast Cell Activation | KIT D816V MutationUnited States, France, United Kingdom, Italy, Germany, Belgium, Spain, Switzerland
-
Hubei Biological Medicine Industrial Technology...UnknownAdvanced Solid Tumors | HRD | BRCA MutationChina
-
Shirley Ryan AbilityLabEunice Kennedy Shriver National Institute of Child Health and Human Development...Active, not recruitingAmputation | Amputation; Traumatic, Limb | Upper Limb Amputation at the Hand | Upper Limb Amputation at the WristUnited States
-
Medipol UniversityRecruitingEvaluation of Functionality of Amputees According to the Medicare Functional K Classification SystemAmputation | Amputation; Traumatic, Leg, LowerTurkey
-
AstraZenecaCompletedEGFR Mutation Status in aNSCLC PatientsKorea, Republic of, Russian Federation, Malaysia, China, Australia, Taiwan, Thailand, Indonesia, Singapore
-
German Breast GroupGlaxoSmithKline; Stemline Therapeutics, Inc.Not yet recruitingBRCA1 Mutation | BRCA2 Mutation | PALB2 Gene Mutation | Hormone Receptor Positive HER-2 Negative Breast Cancer | Advanced or Metastatic Breast CancerGermany
-
Intergroupe Francophone de Cancerologie ThoraciqueCompletedCarcinoma, Non-Small-Cell Lung | KRAS Gene Mutation | ALK Gene Mutation | BRAF Gene MutationFrance
-
Hacettepe UniversityCompleted
-
University of British ColumbiaDublin City UniversityActive, not recruitingGroup B Streptococcus Carrier in ChildbirthCanada
-
Liberating Technologies, Inc.Vivonics, Inc.CompletedLower Limb Amputation Below Knee (Injury) | Amputation | Prosthesis User | Amputation; Traumatic, Leg, Lower | Limb; Absence, Congenital, Lower | Amputation StumpUnited States
-
AnHeart Therapeutics Inc.RecruitingIDH1 Inhibitor AB-218 in Patients With Advanced IDH1 Mutant Cholangiocarcinoma and Other Solid TumorCholangiocarcinoma With IDH1 Mutation | Solid Tumors With IDH1 MutationChina
-
PfizerMedivation, Inc.; Myriad Genetic Laboratories, Inc.TerminatedBreast Neoplasms | BRCA 1 Gene Mutation | BRCA 2 Gene MutationUnited States, Spain, United Kingdom, Germany, France
-
Hadassah Medical OrganizationUnknownBRCA1 Gene Mutation | BRCA2 Gene MutationIsrael
-
Blueprint Medicines CorporationActive, not recruitingNeoplasms | Neoplasms by Histologic Type | Lung Diseases | Neoplasms by Site | Adenocarcinoma | Carcinoma | Carcinoma, Non-Small-Cell Lung | Respiratory Tract Neoplasms | Carcinoma, Bronchogenic | Bronchial Neoplasms | Metastatic Lung Cancer | Antineoplastic Agents | Brain Metastases | Lung Neoplasm Malignant | EGFR... and other conditionsUnited States, Canada, Korea, Republic of, Japan, Taiwan
-
Calithera Biosciences, IncCompletedNSCLC | Solid Tumors | KRAS Gene Mutation | CRCUnited States