Clinical Trials on Gestational Trophoblastic Tumours

Total 18089 results

GOG Foundation
National Cancer Institute (NCI)

Completed

Dactinomycin or Methotrexate in Treating Patients With Low-Risk Gestational Trophoblastic Neoplasia

Hydatidiform Mole | Choriocarcinoma | FIGO Stage I Gestational Trophoblastic Tumor | FIGO Stage II Gestational Trophoblastic Tumor | FIGO Stage III Gestational Trophoblastic Tumor

United States, Korea, Republic of, Canada, Japan, United Kingdom
xiang yang

Recruiting

Biweekly Actinomycin-D Treatment or Multi-day Methotrexate Protocol in Low-risk Gestational Trophoblastic Neoplasia

Gestational Trophoblastic Tumor | Gestational Trophoblastic Neoplasia | Choriocarcinoma | Stage I Gestational Trophoblastic Tumor | Stage II Gestational Trophoblastic Tumor | Stage III Gestational Trophoblastic Tumor | Invasive Mole

China
Hospices Civils de Lyon

Not yet recruiting

Fertility and Pregnancy After Avelumab Treatment (FERTILAVE)

Immune Checkpoint Inhibitors | Gestational Trophoblastic Tumours

France
Gynecologic Oncology Group
National Cancer Institute (NCI); Eastern Cooperative Oncology Group

Completed

Methotrexate Compared With Dactinomycin in Treating Patients With Gestational Trophoblastic Neoplasia

Hydatidiform Mole | Good Prognosis Metastatic Gestational Trophoblastic Tumor | Non-Metastatic Gestational Trophoblastic Tumor | Uterine Corpus Choriocarcinoma

United States
Ding Ma
Shandong University; Huazhong University of Science and Technology; Zhejiang...

Unknown

Methotrexate Single-dose Treatment and Methotrexate/Actinomycin-D Single-dose Treatment in Low-Risk Gestational Trophoblastic Neoplasia (GTN-01)

Gestational Trophoblastic Tumor | Gestational Trophoblastic Neoplasia | Gestational Trophoblastic Disease | Gestational Trophoblastic Neoplasms

China
Gynecologic Oncology Group
National Cancer Institute (NCI)

Completed

Dactinomycin in Treating Patients With Persistent or Recurrent Gestational Trophoblastic Neoplasia

Gestational Trophoblastic Tumor

United States, Norway
Brigham and Women's Hospital
Universidade Federal do Rio de Janeiro; Maternidade Escola da Universidade... and other collaborators

Recruiting

Second Uterine Evacuation for Low-risk Gestational Trophoblastic Neoplasia (ReCure)

Gestational Trophoblastic Neoplasia | Molar Pregnancy | Gestational Trophoblastic Tumor, Non-Metastatic

Brazil
Gynecologic Oncology Group
National Cancer Institute (NCI)

Completed

Second Curettage in Treating Patients With Persistent Non-metastatic Gestational Trophoblastic Tumors

Non-Metastatic Gestational Trophoblastic Tumor | Complete Hydatidiform Mole | Partial Hydatidiform Mole

United States, Canada
Weiguo Lv
Shandong University; Huazhong University of Science and Technology; First Affiliated...

Recruiting

Study of Paclitaxel Plus Cisplatin as the First-line Chemotherapy in High Risk Gestational Trophoblastic Tumor

Gestational Trophoblastic Neoplasms

China
Tracon Pharmaceuticals Inc.

Terminated

Study of TRC105 and Bevacizumab in Patients With Refractory Gestational Trophoblastic Neoplasia (GTN)

Gestational Trophoblastic Neoplasia | Choriocarcinoma | Placental Site Trophoblastic Tumor | Epithelioid Trophoblastic Tumor

United States
Imperial College London
Cancer Research UK

Recruiting

A Feasibility Window Study of Pembrolizumab Prior to Second Evacuation for Post-molar Gestational Trophoblastic Neoplasia

Gestational Trophoblastic Neoplasia | Gestational Trophoblastic Disease | Gestational Trophoblastic Tumor, Recurrent

United Kingdom
Gynecologic Oncology Group
National Cancer Institute (NCI)

Terminated

Pemetrexed Disodium in Treating Patients With Recurrent or Persistent Low-Risk Gestational Trophoblastic Tumor After a Molar Pregnancy

Gestational Trophoblastic Tumor

United States
Hospices Civils de Lyon

Completed

Avelumab in Chemo-resistant Gestational Trophoblastic Neoplasias (TROPHIMMUN)

Gestational Trophoblastic Neoplasias (GTN)

France
Hospices Civils de Lyon
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt...

Recruiting

Avelumab and Methotrexate in in Low-risk Gestational Trophoblastic Neoplasias as First Line Treatment (TROPHAMET)

Gestational Trophoblastic Neoplasias (GTN)

France
Peking Union Medical College Hospital
Jiangsu HengRui Medicine Co., Ltd.

Recruiting

Camrelizumab Plus Apatinib in Patients With High-risk Gestational Trophoblastic Neoplasia

Gestational Trophoblastic Neoplasia

China
Women's Hospital School Of Medicine Zhejiang University
Sun Yat-sen University; Qilu Hospital of Shandong University; Huazhong University...

Recruiting

Study of Hysteroscopic Repeat Curettage as the First-line Treatment in Low-risk Postmolar Gestational Trophoblastic Neoplasia

Gestational Trophoblastic Neoplasia

China
Maher elesawi kamel elesawi

Unknown

Surgery Plus Single Agent Chemotherapy Versus Primary Chemotherapy for Gestational Trophoblastic Neoplasms (SVCGTN)

Gestational Trophoblastic Neoplasms

Egypt
Women's Hospital School Of Medicine Zhejiang University

Recruiting

Study of PD-1 Antibody and Bevacizumab in the Treatment of High-risk GTN After Combined Chemotherapy

Gestational Trophoblastic Neoplasia

China
CHA University
Merck Sharp & Dohme LLC

Not yet recruiting

Phase 2 Trial for Chemo-Resistant Gestational Trophoblastic Neoplasias With Pembrolizumab (CR-GTP) (CR-GTP)

Gestational Trophoblastic Neoplasia

Korea, Republic of
University of Miami
GlaxoSmithKline

Withdrawn

Dostarlimab in Chemoresistant Gestational Trophoblastic Neoplasia

Gestational Trophoblastic Neoplasia

United States
Peking Union Medical College Hospital
Henan Cancer Hospital; Shengjing Hospital; Sun Yat-Sen Memorial Hospital of Sun... and other collaborators

Recruiting

Toripalimab Plus Actinomycin-D as Fist-Line Treatment for GTN With FIGO Score 5-6 (TA56)

Gestational Trophoblastic Neoplasia

China
Sheffield Teaching Hospitals NHS Foundation Trust

Not yet recruiting

The Psychological Impact of GTN on Women Who Have Completed Chemotherapy Treatment (PI-GTN)

Gestational Trophoblastic Neoplasia

United Kingdom
Peking Union Medical College Hospital
Henan Cancer Hospital; Shengjing Hospital; Sun Yat-Sen Memorial Hospital of Sun... and other collaborators

Not yet recruiting

Toripalimab Plus Actinomycin-D as Fist-Line Treatment for GTN With FIGO Score 7 (TA7)

Gestational Trophoblastic Neoplasia

China
Women's Hospital School Of Medicine Zhejiang University

Recruiting

Study of Different Therapeutic Strategies in Hydatidiform Mole With Lung Nodule

Hydatidiform Mole | Gestational Trophoblastic Neoplasia

China
Women's Hospital School Of Medicine Zhejiang University
Qilu Hospital of Shandong University; Huazhong University of Science and Technology and other collaborators

Recruiting

Combination of Methotrexate(MTX) and Actinomycin(ACTD) in the Low Risk Gestational Trophoblastic Neoplasma （GTN） Patients With Score of 5-6

Gestational Trophoblastic Tumor | Effects of Chemotherapy | Drug Toxicity

China
Hospices Civils de Lyon

Recruiting

The French National Reference Centre of GTD (French GTDC)

Hydatidiform Mole | Gestational Trophoblastic Disease | Neoplasm, Trophoblastic | Hydatidiform Mole, Invasive

France
Assiut University

Unknown

Rescue Regimen and High Dose Methotrexate in Management of Presistent Gestational Trophoplastic Neoplasia

Gestational Trophoblastic Disease
Gynecologic Oncology Group
National Cancer Institute (NCI)

Completed

Amifostine in Treating Peripheral Neuropathy in Patients Who Have Received Chemotherapy for Cancer

Unspecified Adult Solid Tumor, Protocol Specific | Gestational Trophoblastic Tumor | Neurotoxicity | Peripheral Neuropathy

United States
Zagazig University

Active, not recruiting

Letrozole as a Prophylaxis From GTN for Complete Mole Patients

Gestational Trophoblastic Disease

Egypt
National Taiwan University Hospital
National Science Council, Taiwan

Unknown

Detection of Human Chorionic Gonadotropin by Interferometry in Gestational Trophoblastic Disease

Trophoblastic Neoplasms

Taiwan
Nilratan Sircar Medical College

Unknown

A Comparison of Single Versus Double Evacuation for Treatment of Hydatidiform Mole

Hydatidiform Mole

India
Women's Hospital School Of Medicine Zhejiang University

Not yet recruiting

A Cohort Study of Hydatidiform Mole

Hydatidiform Mole
University of the Philippines

Completed

RCT on the Efficacy of Methotrexate for the Prevention of GTD

Hydatidiform Mole

Philippines
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Interleukin-11 Plus Filgrastim Prior to Peripheral Stem Cell Transplantation in Patients With Non-Hodgkin's Lymphoma, Hodgkin's Disease, Breast Cancer, or Other Solid Tumors

Sarcoma | Lymphoma | Kidney Cancer | Testicular Germ Cell Tumor | Breast Cancer | Ovarian Cancer | Gestational Trophoblastic Tumor | Neuroblastoma

United States
Peking Union Medical College Hospital

Completed

Camrelizumab Combined With Apatinib for Recurrent Resistant GTN (GTN)

Gestational Trophoblastic Disease

China
Fondazione Policlinico Universitario Agostino Gemelli...

Recruiting

Gestional Trophoblastic Neoplasia Ultrasound Assessment: Titanium Study (TITANIUM)

Describe Typical Gray Scale/Color Doppler Ultrasound Features of Gestational Trophoblastic Neoplasia at the US Examination | To Assess if There Are Differences at the Baseline US Scan Between Low-risk and High-risk Patients | To Identify Ultrasound Predictors of Resistance to First-line... and other conditions

Italy
Memorial Sloan Kettering Cancer Center

Completed

A Global Assessment of Medical, Emotional and Reproductive Concerns in Gestational Trophoblastic Disease Survivors

Gestational Trophoblastic Disease | Uterine Cancer | Cervix Uteri Nos

United States
Peking Union Medical College Hospital
Chineo Medicine (Beijing) Co., Ltd.

Not yet recruiting

Clinical Study on the Safety, Pharmacokinetics, and Efficacy of ScTIL (Genetically Modified Tumor Infiltrating Lymphocytes) in the Treatment of Gynecological Malignancies

Cervical Cancer | Ovarian Cancer | Malignant Trophoblastic Tumor
Baylor College of Medicine

Active, not recruiting

Study of the Genetic and Epigenetic Causes of Recurrent Hydatidiform Moles

Hydatidiform Moles

United States
Vanderbilt-Ingram Cancer Center
National Cancer Institute (NCI)

Completed

Collecting and Storing Tissue and DNA Samples From Patients Undergoing a Donor Stem Cell Transplant

Lymphoma | Myelodysplastic Syndromes | Leukemia | Testicular Germ Cell Tumor | Breast Cancer | Chronic Myeloproliferative Disorders | Ovarian Cancer | Gestational Trophoblastic Tumor | Neuroblastoma | Multiple Myeloma and Plasma Cell Neoplasm | Graft Versus Host Disease | Myelodysplastic/Myeloproliferative Neoplasms

United States
Indiana University School of Medicine
National Cancer Institute (NCI)

Completed

Interleukin-12 in Treating Patients With Hematologic Cancers or Solid Tumors

Lymphoma | Kidney Cancer | Myelodysplastic Syndromes | Leukemia | Testicular Germ Cell Tumor | Breast Cancer | Chronic Myeloproliferative Disorders | Ovarian Cancer | Gestational Trophoblastic Tumor | Neuroblastoma | Multiple Myeloma and Plasma Cell Neoplasm

United States
Cancer Treatment Centers of America

Completed

Biological Therapy Following Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Cancer

Sarcoma | Lymphoma | Kidney Cancer | Myelodysplastic Syndromes | Leukemia | Testicular Germ Cell Tumor | Breast Cancer | Chronic Myeloproliferative Disorders | Ovarian Cancer | Gestational Trophoblastic Tumor | Neuroblastoma | Multiple Myeloma and Plasma Cell Neoplasm

United States
King's College Hospital NHS Trust
University College, London

Recruiting

The Accuracy of Ultrasound Diagnosis of Hydatidiform Moles

Abortion, Spontaneous | Missed Abortion | Miscarriage in First Trimester | Incomplete Miscarriage | Hydatidiform Mole (Diagnosis)

United Kingdom
Hospices Civils de Lyon

Unknown

Chemoresistance of Trophoblastic Tumors (PrediCTTro)

Trophoblastic Tumor

France
Eli Lilly and Company
Gynecologic Oncology Group

Completed

A Trial for Patients With Gestational Trophoblastic Disease

Uterine Neoplasms | Trophoblastic Neoplasms | Hydatidiform Mole | Choriocarcinoma

United States
University of Wisconsin, Madison
National Cancer Institute (NCI)

Completed

Scripted Sexual Health Informational Intervention in Improving Sexual Function in Patients With Gynecologic Cancer

Cervical Cancer | Ovarian Epithelial Cancer | Sexual Dysfunction | Uterine Sarcoma | Vulvar Cancer | Endometrial Cancer | Gestational Trophoblastic Tumor | Vaginal Cancer | Ovarian Germ Cell Tumor | Anxiety Disorder | Female Reproductive Cancer

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Beclomethasone in Treating Patients With Graft-Versus-Host Disease of the Esophagus, Stomach, Small Intestine, or Colon

Lymphoma | Kidney Cancer | Myelodysplastic Syndromes | Leukemia | Testicular Germ Cell Tumor | Breast Cancer | Chronic Myeloproliferative Disorders | Ovarian Cancer | Gestational Trophoblastic Tumor | Neuroblastoma | Multiple Myeloma and Plasma Cell Neoplasm | Graft Versus Host Disease

United States
Barbara Ann Karmanos Cancer Institute
National Cancer Institute (NCI)

Completed

Aprepitant, Granisetron, & Dexamethasone in Preventing Nausea & Vomiting in Pts. Receiving Cyclophosphamide Before a Stem Cell Transplant

Lymphoma | Myelodysplastic Syndromes | Leukemia | Testicular Germ Cell Tumor | Breast Cancer | Chronic Myeloproliferative Disorders | Ovarian Cancer | Gestational Trophoblastic Tumor | Neuroblastoma | Multiple Myeloma and Plasma Cell Neoplasm | Myelodysplastic/Myeloproliferative Neoplasms | Nausea and Vomiting

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Lymphocyte Infusion in Treating Patients With Relapsed Cancer After Bone Marrow or Peripheral Stem Cell Transplantation

Sarcoma | Lymphoma | Kidney Cancer | Myelodysplastic Syndromes | Leukemia | Testicular Germ Cell Tumor | Breast Cancer | Chronic Myeloproliferative Disorders | Ovarian Cancer | Gestational Trophoblastic Tumor | Neuroblastoma | Multiple Myeloma and Plasma Cell Neoplasm

United States
OHSU Knight Cancer Institute
National Cancer Institute (NCI)

Terminated

Blood Samples From Patients on a Clinical Trial to CINV During HSCT

Lymphoma | Myelodysplastic Syndromes | Leukemia | Testicular Germ Cell Tumor | Breast Cancer | Chronic Myeloproliferative Disorders | Ovarian Cancer | Gestational Trophoblastic Tumor | Neuroblastoma | Multiple Myeloma and Plasma Cell Neoplasm | Myelodysplastic/Myeloproliferative Neoplasms | Nausea and Vomiting

United States

Clinical Trials on Gestational Trophoblastic Tumours

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