Clinical Trials on Glaucoma and Ocular Hypertension

Total 13560 results

Alcon Research

Completed

Anecortave Acetate Safety in Patients With Open-Angle Glaucoma or Ocular Hypertension

Open-angle Glaucoma | Oular Hypertension

United States
CHA University
Hanlim Pharm. Co., Ltd.

Unknown

Comparison of Efficacy and Ocular Surface Disease Assessment Between BRIDIN-T Eye Drops 0.15% and ALPHAGAN-P Eye Drops 0.15% in Glaucoma or Ocular Hypertensive Patients : Phase 4, Parallel Group Design, Investigator-blind, Active-control, Randomized, Multi-center Trial

Glaucoma | Ocular Hypertensive

Korea, Republic of
CHA University
Hanlim Pharm. Co., Ltd.

Completed

Comparison of Efficacy and Ocular Surface Assessment Between BRIDIN-plus and Combigan in Glaucoma or Ocular Hypertensive (BCT)

Glaucoma | Ocular Hypertensive

Korea, Republic of
Cairo University

Unknown

Dexmedetomidine as an Additive to Local Anaesthesia to Decrease Intraocular Pressure in Glaucoma Surgery

Glaucoma

Egypt
Zhongshan Ophthalmic Center, Sun Yat-sen University

Recruiting

Macular Pigment Optical Density in Primary Angle-closure Disease

Glaucoma | Glaucoma, Angle-Closure | Macular Pigment Optical Density

China
West Virginia University
University of Pittsburgh

Recruiting

Clarifying the Optimal Application of SLT Therapy Trial (COAST)

Glaucoma and Ocular Hypertension

United States, United Kingdom, Canada
University Hospital, Geneva

Terminated

Prospective,Randomized,Controlled Study to Assess Efficacy,Safety, and Tolerability of SLT vs. PLT in Patients With POAG

Glaucoma and Ocular Hypertension

Switzerland
Zahra Rabbani Khah
Shahid Beheshti University of Medical Sciences

Unknown

Safety Study of Aqueous Suppression After Ahmed Glaucoma Valve (AGV) Implantation

Hypertensive Phase

Iran, Islamic Republic of
Santen SAS

Active, not recruiting

A Phase III Multinational Multicenter Investigator-Masked Randomised Active-Controlled Trial Comparing the Efficacy and Safety of DE-130A With Xalatan® in Patients With Open-Angle Glaucoma or Ocular Hypertension

Ocular Surface Disease | Open-Angle Glaucoma or Ocular Hypertension

France
Nanodropper, Inc.
Aravind Eye Care System

Completed

Evaluation of Nanodropper-mediated Microdrops vs. Standard Drops of 0.5% Timolol Maleate in Glaucoma Patients

Ocular Hypertension | Glaucoma | Glaucoma, Open-Angle | Glaucoma and Ocular Hypertension | Glaucoma, Primary Open Angle

India
Santen Pharmaceutical Co., Ltd.

Recruiting

A Long Term Study of STN1012600 in Subjects With Open Angle Glaucoma or Ocular Hypertension

Open Angle Glaucoma, Ocular Hypertension

Japan
Sanofi

Completed

28-Day Repeated Topical Study to Evaluate the Safety and Activity of 5 Escalating Dose Levels of SAR366234 and One Dose of Latanoprost in Patients With Open Angle Glaucoma or Ocular Hypertension

Open Angle Glaucoma -Ocular Hypertension

United States
Envisia Therapeutics

Completed

Safety and Efficacy of ENV515 Travoprost Extended Release (XR) in Patients With Bilateral Ocular Hypertension or Primary Open Angle Glaucoma

Glaucoma and Ocular Hypertension

United States
American Society Of Thermalism And Climatology Inc

Unknown

Effects of Magnetic Therapy and Seawater Combined in Decreasing Intraocular Presion. (GME)

Primary Open Angle Glaucoma | Hypertension Ocular

United States
Ocular Therapeutix, Inc.

Completed

A Study to Evaluate the Long Term Safety of OTX-TP (Sustained Release Travoprost) Intracanalicular Insert

Open Angle Glaucoma and Ocular Hypertension

United States
Santen Inc.

Completed

A Phase III Study Assessing the Efficacy and Safety of DE-117 Ophthalmic Solution Compared With Timolol Maleate Ophthalmic Solution 0.5% in Subjects With Glaucoma or Ocular Hypertension - Spectrum 3 Study

Glaucoma and Ocular Hypertension

United States
United States Air Force
Alcon Research

Completed

Dry Eye and Irritation Comparison of Latanoprost With the Preservative Versus Travoprost Without Preservative

Ocular Hypertension | Open-Angle Glaucoma | Ocular Dryness | Ocular Irritation

United States
Santen Pharmaceutical Co., Ltd.

Completed

A Study of DE-111A on the Treatment of Open Angle Glaucoma or Ocular Hypertension

Open-angle Glaucoma, Ocular Hypertension

China
Santen Inc.

Completed

A Phase IIb Safety and Efficacy Study of DE-126 Ophthalmic Solution in Primary Open-Angle Glaucoma or Ocular Hypertension- Angel Study

Open-angle Glaucoma, Ocular Hypertension

United States, Japan
Santen Inc.

Completed

A Phase III Study Assessing the Efficacy and Safety of DE-117 Ophthalmic Solution Compared With Timolol Maleate Ophthalmic Solution 0.5% in Subjects With Glaucoma or Ocular Hypertension - Spectrum 4 Study

Glaucoma and Ocular Hypertension

United States
Santen Inc.

Completed

A Study Assessing the Safety and Efficacy of DE-117 Ophthalmic Solution in Patients With POAG or OHT

Glaucoma and Ocular Hypertension

United States
Mati Therapeutics Inc.

Completed

A Dose Evaluation Study for the Latanoprost Punctal Plug Delivery System (L-PPDS) in Subjects With Ocular Hypertension or Open-Angle Glaucoma

Glaucoma | Ocular Hypertension (OH)

United States
Otsuka Beijing Research Institute

Recruiting

OPC-1085EL in the Treatment of Primary Open Angle Glaucoma or Ocular Hypertension in Chinese Subjects

Open Angle Glaucoma or Ocular Hypertension

China
Santen Inc.

Completed

Multi-center Study Assessing the Safety and Efficacy of DE-117 Ophthalmic Solution in Subjects With Primary Open-angle Glaucoma or Ocular Hypertension

Open-angle Glaucoma or Ocular Hypertension

United States
Pro Top & Mediking Company Limited

Completed

Ologen (OculusGen)-Glaucoma and Pterygium Historical Control Study in China Zhong-Shan Hospital

Pterygium | Glaucomas

China
University of Colorado, Denver

Completed

The Diurnal and Nocturnal Effect of Pilocarpine on Intraocular Pressure and Ocular Perfusion Pressure

Hypertension, Ocular | Glaucoma, Open-angle

United States
Qlaris Bio, Inc.

Recruiting

Qlaris Study of QLS-111 in Combination With a PGA for OAG and/or OHT Patients

Glaucoma | Open-angle Glaucoma (OAG) | Ocular Hypertension (OHT)

United States
University of California, San Diego
Bausch & Lomb Incorporated

Completed

Study Comparing the Effects of Latanoprostene Bunod and Timolol on Retinal Blood Vessel Density and Visual Acuity

OAG - Open-Angle Glaucoma | OHT - Ocular Hypertension

United States
University of California, San Diego
Aerie Pharmaceuticals

Withdrawn

Effects of Netarsudil and Timolol on Retinal Blood Vessel Density and Visual Acuity

OAG - Open-Angle Glaucoma | OHT - Ocular Hypertension
Eye Therapies, LLC

Completed

Study Evaluating the Safety and Intraocular Pressure (IOP) Lowering Response of Brimonidine Tartrate Ophthalmic Solution in Subjects With Open Angle Glaucoma or Ocular Hypertension

Glaucoma and Ocular Hypertension

United States
Hillel Yaffe Medical Center

Unknown

Combined Ex-PRESS Implantation Alone or With Phacoemulsification for Glaucoma Associated With Cataract

Glaucoma and Ocular Hypertension
Alcon Research

Completed

AL-54478 Proof of Concept Study

Open-angle Glaucoma (OAG) | Ocular Hypertension (OHT)
Santen Pharmaceutical Co., Ltd.

Completed

A Phase III Study Assessing the Safety and Efficacy of DE-117 Ophthalmic Solution Compared With Latanoprost Ophthalmic Solution in Subjects With OAG or OHT

Open Angle Glaucoma or Ocular Hypertension

Singapore
Santen Pharmaceutical Co., Ltd.

Completed

A Long-term Study of DE-117 Ophthalmic Solution Monotherapy and Concomitant Use of DE-117 Ophthalmic Solution With Timolol Ophthalmic Solution in Patients With OAG or OH: RENGE Study

Open Angle Glaucoma or Ocular Hypertension

Japan
Santen Pharmaceutical Co., Ltd.

Completed

DE-111 Ophthalmic Solution in Patients With Open Angle Glaucoma or Ocular Hypertension

Open Angle Glaucoma or Ocular Hypertension

Japan
Santen Pharmaceutical Co., Ltd.

Completed

A Comparative Confirmatory Study of STN1012600 in Subjects With Primary Open Angle Glaucoma or Ocular Hypertension

Primary Open Angle Glaucoma, Ocular Hypertension

Japan
Aerie Pharmaceuticals

Completed

Study of Netarsudil Ophthalmic Solution in Japanese/Japanese-American Subjects With Open-angle Glaucoma or Ocular Hypertension

Primary Open Angle Glaucoma or Ocular Hypertension

United States
Allergan

Completed

A Comparison of Bimatoprost SR to Selective Laser Trabeculoplasty in Patients With Open-Angle Glaucoma or Ocular Hypertension

Glaucoma | Open-Angle Ocular Hypertension

Spain, United States, Singapore, Australia, Denmark, France, Poland, Russian Federation, Thailand
Pro Top & Mediking Company Limited

Unknown

Ologen(Oculusgen)-Glaucoma and Pterygium Historical Control Study in China Shanghai Sixth People's Hospital

Pterygium | Glaucomas

China
Mati Therapeutics Inc.

Completed

A Dose Evaluation Study of the Effect of Plug Placement on the Efficacy and Safety of the Latanoprost Punctal Plug Delivery System (L-PPDS) in Subjects With Ocular Hypertension or Open-Angle Glaucoma

Glaucoma | Ocular Hypertension (OH)

United States
Santen Inc.

Completed

DE-117 Spectrum 5 Study

Primary Open-angle Glaucoma and Ocular Hypertension

United States
Sensimed AG

Terminated

TF (SENSIMED Triggerfish) in Intraocular Anti-VEGF (Vascular Endothelial Growth Factor) Injection

Open Angle Glaucoma | Neovascular Age Related Macular Degeneration (AMD)

Spain
Santen Pharmaceutical Co., Ltd.

Completed

A Study Assessing the Safety and Efficacy of DE-117 in Subjects With POAG or OH Who Are Non-/Low-responders to Latanoprost: FUJI Study

Primary Open Angle Glaucoma or Ocular Hypertension

Japan
Centre hospitalier de l'Université de Montréal...

Completed

Treatment Outcomes of MicroPulse Trans-scleral Cyclophotocoagulation in Uncontrolled Glaucoma

Glaucoma | Glaucoma, Open-Angle | Glaucoma, Neovascular | Glaucoma Eye | Glaucoma and Ocular Hypertension | Glaucoma, Uncompensated | Glaucoma Secondary

Canada
Nicox Ophthalmics, Inc.

Completed

Phase 2 Dose-Response Study Evaluating the Safety and Efficacy of NCX 470 vs Latanoprost in Subjects With Open-Angle Glaucoma or Ocular Hypertension

Glaucoma, Open-Angle | Hypertension, Ocular

United States
Santen Inc.

Completed

Study Assessing the Safety and Efficacy of DE-117 Ophthalmic Solution Once Daily and Twice Daily in Subjects With Primary Open-Angle Glaucoma SPECTRUM 6

Primary Open-angle Glaucoma and Ocular Hypertension

United States
Daniel Moore
Pfizer

Terminated

Safety Study of Latanoprost Slow Release Insert (Latanoprost SR)

Primary Open Angle Glaucoma (POAG) | Ocular Hypertension (OHT)

United States
Aerie Pharmaceuticals

Completed

Study of Netarsudil Ophthalmic Solution in Subjects With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT)

Primary Open Angle Glaucoma or Ocular Hypertension

United States
Ono Pharma USA Inc

Completed

Single and Multiple Dose Escalation and Two-sequence Crossover Study of ONO-9054 in Patients With Ocular Hypertension or Mild Open-angle Glaucoma

Ocular Hypertension (OHT) | Mild Open Angle-glaucoma (OAG)

United States
OcuTherix, Inc.

Terminated

Safety and Efficacy of Deep Wave Trabeculoplasty (DWT) in Primary Open Angle Glaucoma and Ocular Hypertension

Primary Open-angle Glaucoma (POAG) | Ocular Hypertension (OHT)

Philippines

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