Clinical Trials on Glioblastomas

Total 1672 results

Stemline Therapeutics, Inc.

Completed

Safety and Efficacy Study of SL-701, a Glioma-Associated Antigen Vaccine To Treat Recurrent Glioblastoma Multiforme

Glioblastoma Multiforme | Adult Brain Glioblastoma

United States
National Cancer Institute (NCI)

Completed

Vorinostat, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma

United States
National Cancer Institute (NCI)
NRG Oncology

Completed

Gefitinib and Radiation Therapy in Treating Patients With Glioblastoma Multiforme

Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma

United States
National Cancer Institute (NCI)
Radiation Therapy Oncology Group

Completed

Motexafin Gadolinium, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme or Gliosarcoma

Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma

United States
National Cancer Institute (NCI)

Completed

Carboxyamidotriazole + RT in Treating Patients Newly Diagnosed Supratentorial GBM

Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma

United States
National Cancer Institute (NCI)

Completed

Tipifarnib, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme or Gliosarcoma

Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma

United States
National Cancer Institute (NCI)

Completed

Radiation Therapy and Gadolinium Texaphyrin in Treating Patients With Supratentorial Glioblastoma Multiforme

Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma

United States
National Cancer Institute (NCI)

Suspended

Testing the Addition of an Anti-cancer Drug, Selinexor, to the Usual Chemotherapy Treatment (Temozolomide) for Brain Tumors That Have Returned After Previous Treatment

Recurrent Glioblastoma, IDH-Wildtype | MGMT-Methylated Glioblastoma | Recurrent MGMT-Methylated Glioblastoma

United States
NRG Oncology
National Cancer Institute (NCI); Radiation Therapy Oncology Group

Active, not recruiting

Dose-Escalated Photon IMRT or Proton Beam Radiation Therapy Versus Standard-Dose Radiation Therapy and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma

Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma

United States, Canada
Jazz Pharmaceuticals
Yale University

Completed

TAU-2014-1: Mibefradil and Hypofractionated Re-Irradiation Therapy in Recurrent GBM

Glioblastoma Multiforme (GBM)

United States
National Cancer Institute (NCI)

Completed

Cilengitide, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma

United States
National Cancer Institute (NCI)

Completed

Tipifarnib, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma

United States
National Cancer Institute (NCI)

Completed

Gefitinib in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma

United States
Medical University of Warsaw

Completed

Predictive Values of Preoperative [68Ga]Ga-PSMA-11 PET/CT in Patients With Suspected Brain Tumours of Glial Origin

Glioma, Malignant | Glioma Glioblastoma Multiforme

Poland
Jonsson Comprehensive Cancer Center
National Cancer Institute (NCI)

Recruiting

Magnetic Resonance Imaging for Improving Knowledge of Brain Tumor Biology in Patients With Resectable Glioblastoma

Glioblastoma | Recurrent Glioblastoma | Resectable Glioblastoma

United States
Virginia Commonwealth University
National Cancer Institute (NCI)

Completed

Dimethyl Fumarate, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Adult Giant Cell Glioblastoma | Adult Gliosarcoma | Adult Brain Glioblastoma

United States
Ajay Niranjan
Genentech, Inc.

Completed

Border Zone Stereotactic Radiosurgery With Bevacizumab in Patients With Glioblastoma Multiforme

Glioblastoma Multiforme | Glioblastoma - Category

United States
University of Alabama at Birmingham
National Cancer Institute (NCI)

Active, not recruiting

Genetically Engineered HSV-1 Phase 1 Study for the Treatment of Recurrent Malignant Glioma (M032-HSV-1)

Recurrent Glioblastoma Multiforme | Progressive Glioblastoma Multiforme | Anaplastic Astrocytoma or Gliosarcoma

United States
Hideho Okada, MD, PhD
National Cancer Institute (NCI); California Institute for Regenerative Medicine...

Recruiting

Anti-EGFRvIII synNotch Receptor Induced Anti-EphA2/IL-13Ralpha2 CAR (E-SYNC) T Cells

Glioblastoma | Recurrent Glioblastoma | EGFR Gene Mutation | MGMT-Unmethylated Glioblastoma

United States
ImmVira Pharma Co. Ltd

Not yet recruiting

A Clinical Study of Intratumoral MVR-C5252 (C5252) in Patients With Recurrent or Progressive Glioblastoma

Glioblastoma | Solid Tumor | Glioblastoma Multiforme | Glioblastoma Multiforme of Brain

United States
National Cancer Institute (NCI)

Recruiting

Testing the Ability of AMG 232 (KRT 232) to Get Into the Tumor in Patients With Brain Cancer

Glioblastoma | Gliosarcoma | Recurrent Glioblastoma | MGMT-Unmethylated Glioblastoma

United States
CNS Pharmaceuticals, Inc.
Worldwide Clinical Trials

Active, not recruiting

A Study of Berubicin in Adult Subjects With Recurrent Glioblastoma Multiforme

Glioblastoma Multiforme, Adult

United States, Spain, France, Switzerland, Italy
Mashhad University of Medical Sciences

Unknown

Efficacy of Two Temozolomide Regimens in Adjuvant Treatment of Patients With Brain High Grade Glioma

Glioblastoma Multiforme of Brain | Anaplastic Astrocytoma of Brain

Iran, Islamic Republic of
National Cancer Institute (NCI)

Completed

Erlotinib and Temozolomide With Radiation Therapy in Treating Patients With Glioblastoma Multiforme or Other Brain Tumors

Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma

United States
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

Safety and Efficacy Study to Treat Recurrent Grade 4 Malignant Brain Tumors

Recurrent Glioblastoma Multiforme
Huashan Hospital
Shandong Provincial Hospital

Unknown

Gut Microbiota and Glioblastoma Multiforme Prognosis

Gut Microbiota, Glioblastoma Multiforme, Microglia, Tumor Related Macrophagocyte, Prognosis
University of Alberta
Capital Health, Canada

Completed

The Safety and Efficacy of DCA for the Treatment of Brain Cancer

Malignant Gliomas, Glioblastoma Multiforme

Canada
National Cancer Institute (NCI)

Completed

Arsenic Trioxide Plus Radiation Therapy in Treating Patients With Newly Diagnosed Malignant Glioma

Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma

United States
Nader Sanai
GlaxoSmithKline; University of California, San Francisco; Barrow Neurological... and other collaborators

Recruiting

Trial of Niraparib in Participants With Newly-diagnosed Glioblastoma and Recurrent Glioma

Glioma | Glioblastoma | Glioblastoma Multiforme | GBM | Glioma, Malignant | Glioblastoma Multiforme of Brain

United States
National Cancer Institute (NCI)

Completed

Cediranib, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma

Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma

United States
Celularity Incorporated

Withdrawn

CYNK-001 IV and IC in Combination With IL2 in Surgical Eligible Recurrent GBM With IDH-1 Wild Type (CYNK001GBM02)

Glioblastoma | Glioblastoma Multiforme | Giant Cell Glioblastoma | Astrocytoma, Grade IV

United States
Boston Scientific Corporation

Recruiting

A Feasibility Study to Evaluate the Safety of the TheraSphere Glioblastoma (GBM) Device in Patients With Recurrent GBM (FRONTIER)

Glioblastoma Multiforme | Recurrent Glioblastoma

United States
Brighton and Sussex University Hospitals NHS Trust

Completed

Brain Imaging to Predict Toxicity in Elderly Patients After Radiotherapy (BRITER)

Quality of Life | Radiation Toxicity | Glioblastoma Multiforme, Adult

United Kingdom
Sun Yat-sen University

Unknown

A Prospective, Open-label, Single-arm Clinical Study

Recurrent Glioblastoma Multiforme

China
Novartis Pharmaceuticals

Completed

Phase Ib/II Study of Buparlisib Plus Carboplatin or Lomustine in Patients With Recurrent Glioblastoma Multiforme

Recurrent Glioblastoma Multiforme

United States, Belgium, Australia, Spain, France, Canada
Northwell Health

Completed

Super-Selective Intraarterial Cerebral Infusion of Cetuximab (Erbitux) for Treatment of Relapsed/Refractory GBM and AA

GBM | Anaplastic Astrocytoma | Glioblastoma Multiforme (GBM) | ANAPLASTIC ASTROCYTOMA (AOA)

United States
CASI Pharmaceuticals, Inc.

Completed

Phase 2 Study of Panzem Nanocrystal Colloidal Dispersion (NCD) in Combination With Fixed-Dose Temozolomide to Patients With Recurrent Glioblastoma Multiforme (GBM)

Recurrent Glioblastoma Multiforme

United States
National Cancer Institute (NCI)

Completed

Feasibility and Preliminary Efficacy of a Mindfulness-based Intervention for Children and Young Adults With High Grade or High-Risk Cancer and Their Caregivers

Sarcoma | Leukemia | Astrocytoma | Brain Cancer | Glioblastomas

United States
Royan Institute
Tehran University of Medical Sciences

Recruiting

Nk Cell Therapy for Recurrent Glioblastoma Multiform Patients

Recurrent Glioblastoma | Glioblastoma Multiform

Iran, Islamic Republic of
WPD Pharmaceuticals Sp. z o.o.
National Center for Research and Development, Poland; Worldwide Clinical Trials

Recruiting

Berubicin in Adult Patients With Recurrent Glioblastoma Multiforme (WHO Grade IV)

Recurrent Glioblastoma Multiforme

Poland
Second Affiliated Hospital, School of Medicine,...
BoYuan RunSheng Pharma (Hangzhou) Co., Ltd.

Unknown

Pilot Study of B7-H3 CAR-T in Treating Patients With Recurrent and Refractory Glioblastoma

Recurrent Glioblastoma | Refractory Glioblastoma

China
Northwell Health

Recruiting

Repeated Superselective Intraarterial Cerebral Infusion (SIACI) of Bevacizumab With Temozolomide and Radiation Compared to Temozolomide and Radiation Alone in Newly Diagnosed GBM

Glioblastoma | Brain Cancer | Glioblastoma Multiforme | GBM | Glioma, Malignant | Glioblastoma, IDH-wildtype | Glioblastoma Multiforme, Adult

United States
University of Alberta

Recruiting

Role of Repeat Resection in Recurrent Glioblastoma

Recurrent Glioblastoma | Glioblastoma - Category

Canada
Second Affiliated Hospital, School of Medicine,...
Huizhou Municipal Central Hospital; BoYuan RunSheng Pharma (Hangzhou) Co.,... and other collaborators

Recruiting

B7-H3 CAR-T for Recurrent or Refractory Glioblastoma

Recurrent Glioblastoma | Refractory Glioblastoma

China
Prof. Franciszek Lukaszczyk Memorial Oncology Center
NovoCure GmbH

Active, not recruiting

TTFields and Radiosurgery of Recurrent Glioblastoma +/- 18F-Fluoro-Ethyl-Thyrosine (TaRRGET)

Glioblastoma Multiforme | Recurrent Glioblastoma

Poland
Washington University School of Medicine

Completed

Evaluation of FDOPA-PET/MRI in Pediatric Patients With CNS Tumors

Glioma | Ganglioglioma | Ganglioneuroma | Astrocytoma, Oligoastrocytoma, Mixed | Glioblastoma Multiforme Glioma

United States
Children's Hospital Medical Center, Cincinnati

Terminated

Treatment of Newly Diagnosed Brain Tumors With Chemotherapy and Radiation Using Cells Modified for Chemoprotection and an Experimental Drug to Decrease the Tumor Cell Resistance to Chemotherapy

Glioblastoma Multiforme (WHO Grade IV) | Anaplastic Astrocytoma (WHO Grade III)

United States
Accendatech USA Inc.
Avance Clinical Pty Ltd.; C3 Research Associates

Recruiting

A Study to Evaluate Safety and Efficacy of ACT001 and Anti-PD-1 in Patients With Surgically Accessible Recurrent Glioblastoma Multiforme

Recurrent Glioblastoma Multiforme(GBM)

United States
National Cancer Institute (NCI)

Suspended

A Study Testing the Effect of Immunotherapy (Ipilimumab and Nivolumab) in Patients With Recurrent Glioma With Elevated Mutational Burden

Diffuse Glioma | Secondary Glioblastoma | Glioblastoma, IDH-Wildtype | Astrocytoma, IDH-Mutant, Grade 4

United States, Puerto Rico
National Cancer Institute (NCI)

Completed

Dose Escalation Trial of Re-irradiation in Good Prognosis Recurrent Glioblastoma

Glioblastoma Multiforme | Gliosarcoma | Giant Cell Glioblastoma | Astrocytoma, Grade IV

United States

Clinical Trials on Glioblastomas

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