Clinical Trials on Grade 4 Perineal Tear

Total 147 results

London North West Healthcare NHS Trust

Recruiting

CArE for OAsI Study: Care Pathways and Anorectal Evaluation for OASI Associated Incontinence (CArE for OAsI)

Anal Incontinence | Faecal Incontinence | Follow-up | Biofeedback | Obstetric Anal Sphincter Injury | Urogynaecology | Urgency | Severe Perineal Trauma | Grade 3 Perineal Tear | Grade 4 Perineal Tear | Deferral Time | Pathways | Review | Endo-anal Ultrasound

United Kingdom
Centre Hospitalier Universitaire de Besancon

Not yet recruiting

In Vivo Evaluation of Perineal Mechanical Properties During Childbirth (MecaPer)

Perineal Tear | Perineum; Rupture | Perineum; Tear
Hadassah Medical Organization

Completed

Biologic Glue for First Degree Perineal Tears

Grade 1 Perineal Tears

Israel
Instituto Materno Infantil Prof. Fernando Figueira

Completed

Vocalization for the Second Stage of Labor (VOCAL) (VOCAL)

Perineal Tear | Perineum; Rupture

Brazil
Yooyoung Pharmaceutical Co., Ltd.

Completed

Clinical Trial of YYD701-2 for Treatment of Nasolabial Folds

Wrinkle Severity Rating Scale(WSRS) Grade 3 (Moderate) or 4 (Severe) of Nasolabial Folds

Korea, Republic of
University of Zurich

Completed

Application of a Perineal Protection Device in Vacuum-assisted Births

Perineal Tear | Vaginal Tear

Switzerland
Clinical Research Centre, Malaysia

Completed

Comparison Between Rectal Suppository Acetaminophen and Diclofenac Sodium as Analgesia for Postpartum Perineal Tear (SuPPerP)

Perineal Tear | Perineal Laceration (Obstetric)
Pharmanutra S.p.a.
NEA Clinical S.r.l.

Completed

LIKEST Study: Lipocet® in Adults With Primary Knee Osteoarthritis Grade 3-4

Primary Knee Osteoarthritis Grade 3 - 4

Georgia
Massachusetts General Hospital

Enrolling by invitation

The Patient Positioning for Perineal Protection Study (4P)

Perineal Tear | Delivery; Trauma | Perineal Laceration

United States
Mayo Clinic

Not yet recruiting

An Investigational Scan (Ga-68 PSMA-11 PET/CT) for Detection of Disease Recurrence or Progression in Patients With Glioma

WHO Grade 3 Glioma | WHO Grade 2 Glioma | WHO Grade 4 Glioma

United States
Poitiers University Hospital

Recruiting

Descriptive Evaluation of Expulsive Efforts During Pregnancy in Term Nulliparous Women by Measurement of Intra Bladder Pressure: Pilot Observational Study. (ACCOUPIV)

Perineal Tear

France
Helsingborgs Hospital
Skane University Hospital; Lund University Hospital

Completed

A Device Designed to Protect the Perineum During Labor

Perineal Tear

Sweden
Hasanuddin University

Completed

Lidocaine, Povidone Iodine, and Honey Application on Second-degree Perineal Tear Healing

Perineal Tear

Indonesia
Ethicon, Inc.

Completed

A Study Comparing Topical Skin Adhesive or Sutures for Closure Due to Episiotomy or Perineal Tears Following Childbirth

Episiotomy | Perineal Tear

United States
Biocodex

Recruiting

The Effect of Mucogyne® Gel on Wound Healing (ARTHEMIS)

Perineal Tear and Episiotomy

France
University of Jaén

Completed

Continuous Versus Discontinuous Suture in the Perineals Lesions

Perineal Tear | Episiotomy Wound
Federico II University

Completed

Hands on vs Hands Off for Perineal Laceration

Perineal Tear

Italy
Northwestern University
National Cancer Institute (NCI); BrainUp Inc

Not yet recruiting

Triapine in Combination With Temozolomide for the Treatment of Patients With Recurrent Glioblastoma

Recurrent WHO Grade 2 Glioma | Recurrent Glioblastoma, IDH-Wildtype | Recurrent WHO Grade 3 Glioma | Recurrent WHO Grade 4 Glioma

United States
Stockholm South General Hospital

Unknown

Perineorraphy Versus Pelvic Floor Exercise - a Randomized Trial

Perineal Tear Resulting From Childbirth

Sweden
Universidade do Porto

Completed

Perineal Massage and Warm Compresses - RCT for Reduce Perineal Trauma During Labor (PeMWaC)

Perineal Tear Resulting From Childbirth

Portugal
Ostergotland County Council, Sweden

Completed

Short Anovaginal Distance is Associated With Obstetric Anal Sphincter Rupture (AVD and OASR)

Perineal Tear | Obstetric Trauma
University Hospital Muenster
Isotope Technologies Munich (ITM) Oncologics; Helmholtz Zentrum München Deutsches...

Recruiting

Radioimmunotherapy With Lu-177 Labeled 6A10 Fab-fragments in Patients With Glioblastoma After Standard Treatment (RIT in GBM)

Glioblastom WHO Grade 4

Germany
Universidade Federal de Pernambuco

Unknown

Effectiveness of Warm Packs, Perineal Massage and Hands Off During Labour in the Perineal Outcomes.

Perineal Tear

Brazil
HaEmek Medical Center, Israel
Holy Family Hospital, Nazareth, Israel

Recruiting

Skin Glues Compared to Running Sutures for Perineal Skin Repair After Vaginal Delivery. A Randomized Controlled Trial

Perineal Tear

Israel
Augusta University

Unknown

The Effect of Neuraxial Morphine (Duramorph) on Pain Control

Perineal Tear

United States
K-Group, Beta, Inc., a wholly owned subsidiary...

Recruiting

A Study of ZN-c3 in Subjects With High-Grade Serous Ovarian, Fallopian Tube or Primary Peritoneal Cancer

High-Grade Serous Ovarian, Fallopian Tube or Primary Peritoneal Cancer

United States, Australia, France, Poland
Shanghai Jiao Tong University School of Medicine

Completed

Study of Danggui Buxue Decoction in Preventing Neutropenia (DIPE)

Febrile Neutropenia | Grade 3/4 Neutropenia

China
Instituto Materno Infantil Prof. Fernando Figueira

Suspended

Low Power Laser for Spontaneous Perineal Laceration (LASER)

Perineal Tear

Brazil
Universita di Verona

Completed

Selective Use of Episiotomy: the Impact on Perineal Trauma. (SEPT-1)

Perineal Tear | Delivery; Injury, Maternal | Episiotomy Wound

Italy
University Hospital, Geneva

Completed

The Application of Honey on Perineal Sutures

Pain | Burns | Perineal Tear

Switzerland
M.D. Anderson Cancer Center

Recruiting

Pembrolizumab and Lenvatinib for the Treatment of Serous Ovarian Cancer Patients

Recurrent Primary Peritoneal High Grade Serous Adenocarcinoma | High Grade Ovarian Serous Adenocarcinoma | Recurrent High Grade Fallopian Tube Serous Adenocarcinoma | Recurrent High Grade Ovarian Serous Adenocarcinoma | High Grade Fallopian Tube Serous Adenocarcinoma | Peritoneal High Grade...

United States
Northern Sydney and Central Coast Area Health Service
Merck KGaA, Darmstadt, Germany

Unknown

Temozolomide and Procarbazine With Cilengitide for Patients With Glioblastoma Multiforme Without Methylation of the MGMT Promoter Gene (ExCentric)

Newly Diagnosed Non Methylated Glioblastoma Multiforme Grade 4

Australia
Azienda Sanitaria-Universitaria Integrata di Udine

Recruiting

TRESPASS Clinical Study

Perineal Laceration, Tear, or Rupture During Delivery

Italy
Western Galilee Hospital-Nahariya

Recruiting

Use of Warm Compresses During the Second Stage and the Risk of Perineal Tears

Perineum; Tear

Israel
Tribhuvan University, Nepal

Completed

The Effect of Using Perineal Warm Compress Techniques During the Second Stage of Labor on Perineal Outcomes

Pain | Labor | Perineal Tear | Heat Therapy

Nepal
Samus Therapeutics, Inc.

Terminated

Study of Icapamespib (PU-AD) in Patients With Recurrent Malignant Glioma (Glio)

Recurrent Glioblastoma Multiforme (GBM) | Grade 3 Isocitrate Dehydrogenase (IDH) Wildtype Astrocytoma | Grade 3 or 4 Astrocytoma | Glioblastoma Surgery

United States
University of Calgary
Alberta Health services; Alberta Innovates Health Solutions

Recruiting

Optimizing Postpartum Pelvic Health Through Self-Scar Tissue Massage of Episiotomy and Perineal Scar Tissue A Pilot RCT (EPIS)

Scar Tissue | Perineal Tear | Episiotomy; Complications | Vaginal Tear Resulting From Childbirth

Canada
Hopital Foch

Completed

Post-partum Perineal Pain - Chirocaine® (EPISIO)

Episiotomy | Vaginal Tear | Post-partum Perineal Pain

France
Memorial Sloan Kettering Cancer Center
Bristol-Myers Squibb

Active, not recruiting

A Study of Carboplatin and Paclitaxel Chemotherapy With Nivolumab With or Without Ipilimumab in Patients With Ovarian Cancer

Primary Peritoneal Cancer | Fallopian Tube | High Grade Serous Ovarian

United States
National Cancer Institute (NCI)
NRG Oncology

Recruiting

Testing the Addition of Ipatasertib to the Usual Chemotherapy Treatment (Paclitaxel and Carboplatin) for Stage III or IV Epithelial Ovarian Cancer

Ovarian Endometrioid Adenocarcinoma | Primary Peritoneal High Grade Serous Adenocarcinoma | Fallopian Tube Endometrioid Adenocarcinoma | Ovarian High Grade Serous Adenocarcinoma | Fallopian Tube High Grade Serous Adenocarcinoma | Primary Peritoneal Endometrioid Adenocarcinoma | Stage III Fallopian... and other conditions

United States
Region Skane
Karolinska University Hospital

Completed

One Plus One Equals Two, Will That do? (Oneplus)

Pelvic Floor Disorders | Perineal Tear | Second Stage of Labor | Experience, Life | Sphincter (Anal); Perineal Rupture, Obstetric

Sweden
Duke University
Genentech, Inc.

Completed

Bevacizumab Beyond Progression (BBP) (BBP)

Glioblastoma | Malignant Glioma | Gliosarcoma | Grade 4 Malignant Glioma

United States
National Cancer Institute (NCI)
NRG Oncology

Active, not recruiting

Comparison of Standard of Care Treatment With a Triplet Combination of Targeted Immunotherapeutic Agents

Ovarian Seromucinous Carcinoma | Recurrent Ovarian High Grade Serous Adenocarcinoma | Recurrent Platinum-Resistant Ovarian Carcinoma | Fallopian Tube Mucinous Adenocarcinoma | Recurrent Fallopian Tube Clear Cell Adenocarcinoma | Recurrent Fallopian Tube Endometrioid Adenocarcinoma | Recurrent... and other conditions

United States, Puerto Rico
National Cancer Institute (NCI)

Suspended

A Study Testing the Effect of Immunotherapy (Ipilimumab and Nivolumab) in Patients With Recurrent Glioma With Elevated Mutational Burden

Diffuse Glioma | Secondary Glioblastoma | Glioblastoma, IDH-Wildtype | Astrocytoma, IDH-Mutant, Grade 4

United States, Puerto Rico
Linkoeping University
Ostergotland County Council, Sweden

Completed

Pre-surgery Physiotherapy for Patients With Specific Low Back Pain (PREPARE)

Spinal Stenosis | Lumbar Spine Disc Herniation | Spondylolisthesis, Grade 4

Sweden
Academic and Community Cancer Research United
National Cancer Institute (NCI)

Not yet recruiting

Retifanlimab With Bevacizumab and Hypofractionated Radiotherapy for the Treatment of Recurrent Glioblastoma

Recurrent Glioblastoma | Recurrent WHO Grade 4 Glioma

United States
Sunnybrook Health Sciences Centre

Terminated

Perineal Local Infiltration Study (PLIS)

Anesthesia, Local | Episiotomy; Complications | Second Degree Perineal Tear During Delivery - Delivered

Canada
Knut Haadem

Unknown

The Effect of the Modified Perineal Protection Device During Delivery

Perineal Tears.

Sweden
London North West Healthcare NHS Trust
Imperial College Healthcare NHS Trust

Not yet recruiting

Consequences of Obstetric Anal Sphincter Injuries on Maternal Psychology and Relationship Experience (COMPaRE)

Mental Health Impairment | Obstetric Complication | Incontinence | Perineal Tear | Obstetric Trauma | Relation, Mother-Child | Relation, Family

United Kingdom
Munzur University

Completed

Perineal Massage Performed During the Labour

Satisfaction, Patient | Delivery Problem | Perineal Tear | Pain, Labor | Perineum; Injury | Childrearing

Turkey

Clinical Trials on Grade 4 Perineal Tear

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