Clinical Trials on Gram Negative Meningitis

Total 6646 results

Women and Infants Hospital of Rhode Island

Not yet recruiting

Assessing Interventions to Increase Tdap Acceptance for Non-birthing Partners in Pregnancy (ITAPP)

Vaccine Exposure During Pregnancy | Tdap - Tetanus, Diphtheria and Acellular Pertussis Vaccination | Non-birthing Partner Vaccination in Pregnancy
Nanjing Medical University

Recruiting

Thymosin α1 Use in Rheumatic Heart Disease Patients Undergoing Cardiac Surgery on Cardiopulmonary Bypass

Rheumatic Heart Disease | Cardiopulmonary Bypass | Immunotherapy

China
David Binion, MD
Merck Sharp & Dohme LLC

Terminated

Prevention of Recurrent Clostridium Difficile Infection (CDI) in Patients With Inflammatory Bowel Disease (IBD).

Inflammatory Bowel Diseases | Crohn Disease | Ulcerative Colitis | C. Diff. Infections

United States
AN2 Therapeutics, Inc

Active, not recruiting

Study of Epetraborole in Patients With Treatment-refractory MAC Lung Disease

MAC Lung Disease | Treatment Refractory MAC Lung Disease

United States, Australia, Japan, Korea, Republic of
Global Alliance for TB Drug Development

Completed

Various Doses and Durations of Linezolid Plus Bedaquiline & Pretomanid in Participants With Drug Resistant Tuberculosis (ZeNix)

Tuberculosis | Tuberculosis, Pulmonary | Tuberculosis, Multidrug-Resistant | Extensively Drug-Resistant Tuberculosis | Tuberculosis, MDR | XDR-TB | Pre-XDR-TB

South Africa, Russian Federation, Georgia, Moldova, Republic of
Population Health Research Institute
Bayer; University of Cape Town

Completed

INVestIgation of rheumatiC AF Treatment Using Vitamin K Antagonists, Rivaroxaban or Aspirin Studies, Non-Inferiority (INVICTUS-VKA)

Rheumatic Heart Disease

Botswana, Philippines, Zimbabwe, India, China, Egypt, Ethiopia, Uganda, Brazil, South Africa, Cameroon, Tanzania, Kenya, Zambia, Kazakhstan, Kyrgyzstan, Malawi, Mexico, Mozambique, Nepal, Nigeria, Pakistan, Paraguay, Rwanda, Sudan
Population Health Research Institute
University of Cape Town

Withdrawn

INVestIgation of rheumatiC AF Treatment Using Vitamin K Antagonists, Rivaroxaban or Aspirin Studies, Superiority (INVICTUS-ASA)

Rheumatic Heart Disease
National Institute of Allergy and Infectious Diseases...

Completed

Rheumatic Heart Disease Prevalence in Leon, Nicaragua

Streptococcus Group A

Nicaragua
Yonsei University

Withdrawn

Safety and Immunogenicity Study of GX-70 in TB Patient

Pulmonary Tuberculoses | Treatment Failure | High Risk Factors for Relapse
Sanofi Pasteur, a Sanofi Company

Completed

Study of an Investigational Pneumococcal Vaccine at Three Dose Levels in Healthy Adults

Pneumococcal Infections | Streptococcus Pneumoniae Infections | Pneumococcal Pneumonia

Switzerland
Pfizer

Completed

An Evaluation Of Three Dose Levels Of 3-Antigen Staphylococcus Aureus Vaccine (SA3Ag) In Healthy Adults

Bacterial Infections | Staphylococcal Skin Infections | Staphylococcal Infections | Staphylococcal Vaccines | Immunotherapy, Active

Australia
Oxford University Clinical Research Unit, Vietnam
Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam

Completed

Pneumonia in Tetanus Study (BP)

Tetanus
Ruijin Hospital
Pfizer

Unknown

Linezolid Alone or Combined With Carbapenem Against Methicillin-resistant Staphylococcus Aureus (MRSA) in Ventilator-associated Pneumonia

Pneumonia, Ventilator-Associated | Methicillin-resistant Staphylococcus Aureus
Pharmacia

Completed

A Three-Arm Comparative Trial for the Treatment of MAC Bacteremia in AIDS: A Clarithromycin/Ethambutol Regimen Containing Rifabutin (450 Mg) or Rifabutin (300 Mg) or Placebo

HIV Infections | Mycobacterium Avium-Intracellulare Infection

United States
National Cancer Institute (NCI)

Active, not recruiting

Paclitaxel With or Without Carboplatin and/or Bevacizumab Followed by Doxorubicin and Cyclophosphamide in Treating Patients With Breast Cancer That Can Be Removed by Surgery

Triple-Negative Breast Carcinoma | Male Breast Carcinoma | Stage IIA Breast Cancer AJCC v6 and v7 | Stage IIB Breast Cancer AJCC v6 and v7 | Stage IIIA Breast Cancer AJCC v7

United States
National Cancer Institute (NCI)

Active, not recruiting

Azacitidine and Entinostat in Treating Patients With Advanced Breast Cancer

Recurrent Breast Carcinoma | Triple-Negative Breast Carcinoma | Male Breast Carcinoma | Stage IV Breast Cancer AJCC v6 and v7 | Stage IIIC Breast Cancer AJCC v7

United States
University of Washington
National Cancer Institute (NCI)

Completed

FLT PET in Measuring Treatment Response in Patients With Newly Diagnosed Estrogen Receptor-Positive, HER2-Negative Stage I-III Breast Cancer

Stage IIIA Breast Cancer | Stage IIIB Breast Cancer | Stage IA Breast Cancer | Stage IB Breast Cancer | Stage IIA Breast Cancer | Stage IIB Breast Cancer | Stage IIIC Breast Cancer | Estrogen Receptor Positive | HER2/Neu Negative | Male Breast Carcinoma

United States
Exelixis

Recruiting

Study of XB002 in Subjects With Solid Tumors (JEWEL-101)

Cervical Cancer | Pancreatic Cancer | Non Small Cell Lung Cancer | Triple Negative Breast Cancer | Endometrial Cancer | Epithelial Ovarian Cancer | Metastatic Castration-resistant Prostate Cancer | Hormone Receptor-positive Breast Cancer | SCCHN | Esophageal SCC | Tissue Factor-Expressing Solid Tumors

United States, Spain, Australia, Belgium, France, Italy, Netherlands, United Kingdom, Korea, Republic of
Cofactor Genomics, Inc.
Curebase Inc.

Recruiting

A Multicenter Cancer Biospecimen Collection Study

Renal Cell Carcinoma | Cervical Cancer | Hepatocellular Carcinoma | Colorectal Cancer | Triple Negative Breast Cancer | Small-cell Lung Cancer | Esophageal Squamous Cell Carcinoma | Urothelial Carcinoma | Cancer of Head and Neck | Lung Cancer, Nonsmall Cell | Gastroesophageal Junction Adenocarcinoma

United States
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Recruiting

Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery

Head and Neck Squamous Cell Carcinoma | Stage III Hypopharyngeal Carcinoma AJCC v8 | Stage III Laryngeal Cancer AJCC v8 | Stage III Lip and Oral Cavity Cancer AJCC v8 | Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8 | Hypopharyngeal Squamous Cell Carcinoma | Laryngeal Squamous Cell Carcinoma and other conditions

United States
Incyclix Bio

Recruiting

Open-Label Study to Evaluate the Safety, Tolerability, PK, and Efficacy of INX-315 in Patients With Advanced Cancer (INX-315-01)

Breast Cancer | Ovarian Cancer | Solid Tumor | Metastatic Cancer | Advanced Cancer | Breast Cancer Metastatic | Hormone Receptor Positive Tumor | Human Epidermal Growth Factor 2 Negative Carcinoma of Breast | CCNE1 Amplification

United States, Australia
Sohag University

Recruiting

Comparison Between Negative Pressure Wound Therapy and Conventional Wound Dressings Before and After Split-Thickness Skin Grafting in Diabetic Foot Wounds

Diabetic Foot | Negative-Pressure Wound Therapy

Egypt
Emory University
National Cancer Institute (NCI)

Recruiting

Letrozole With and Without Simvastatin for the Treatment of Stage I-III Hormone Receptor Positive, HER2 Negative Breast Cancer

Anatomic Stage I Breast Cancer AJCC v8 | Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage III Breast Cancer AJCC v8 | Invasive Breast Carcinoma | Hormone Receptor-Positive Breast Carcinoma | HER2-Negative Breast Carcinoma

United States
Ohio State University Comprehensive Cancer Center
National Cancer Institute (NCI)

Recruiting

Endocrine Therapy Fulvestrant & Palbociclib or Aromatase Inhibitor Therapy in Treating Older Patients With Hormone Responsive Breast Cancer That Cannot Be Removed by Surgery

Stage IIIA Breast Cancer | Stage IIIB Breast Cancer | Stage IA Breast Cancer | Stage IB Breast Cancer | Stage IIA Breast Cancer | Stage IIB Breast Cancer | Stage IIIC Breast Cancer | HER2/Neu Negative | Estrogen Receptor and/or Progesterone Receptor Positive

United States
National Cancer Institute (NCI)

Active, not recruiting

Exemestane With or Without Entinostat in Treating Patients With Recurrent Hormone Receptor-Positive Breast Cancer That is Locally Advanced or Metastatic

Anatomic Stage III Breast Cancer AJCC v8 | Anatomic Stage IV Breast Cancer AJCC v8 | Recurrent Breast Carcinoma | HER2/Neu Negative | Breast Adenocarcinoma | Metastatic Breast Carcinoma | Locally Advanced Breast Carcinoma

United States, South Africa
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Terminated

Low-Intensity Chemotherapy and Blinatumomab in Treating Patients With Philadelphia Chromosome Negative Relapsed or Refractory Acute Lymphoblastic Leukemia

Recurrent B Acute Lymphoblastic Leukemia | Refractory B Acute Lymphoblastic Leukemia | Philadelphia Chromosome Negative

United States
National Cancer Institute (NCI)

Withdrawn

Ixazomib and Dexamethasone With or Without Venetoclax in Treating Patients With Non-t(11;14) Relapsed or Refractory Multiple Myeloma

Refractory Plasma Cell Myeloma | Recurrent Plasma Cell Myeloma | t(11;14) Negative
Memorial Sloan Kettering Cancer Center
Jazz Pharmaceuticals

Withdrawn

Intravenous Erwinia Chrysanthemi Asparaginase in Patients With Newly Diagnosed Philadelphia Chromosome Negative Acute Lymphoblastic Leukemia Aged 60 Years or Older

Acute Lymphoblastic Leukemia (ALL) | Newly Diagnosed Philadelphia Chromosome Negative | Aged 60 Years or Older

United States
National Cancer Institute (NCI)

Terminated

RO4929097 And Exemestane in Treating Pre- and Postmenopausal Patients With Advanced or Metastatic Breast Cancer

Stage IV Breast Cancer | Recurrent Breast Carcinoma | Stage IIIB Breast Cancer | Stage IIIC Breast Cancer | Estrogen Receptor Positive | HER2/Neu Negative | Male Breast Carcinoma

United States
Novartis Pharmaceuticals

Completed

Effect of Zoledronic Acid as Anti-Cancer Treatment in Metastatic Breast Cancer Patients (MACS1295)

First or Second Line HER2-negative Breast Cancer | Metastatic Disease Without Bone Metastasis

United States
Juerg Hafner

Recruiting

Painless Sharp Wound Debridement With Lidocaine-23%-Tetra-caine-7% Gel Versus EMLA 5% Cream (LIDOTETRA)

Ulcer, Leg | Ulcus Cruris | Ulcer Venous | Ecthyma

Switzerland
University of Stellenbosch
New York University

Recruiting

Pre- and Post-treatment Lung Microbiota, Metabolome and Immune Signatures at the Site of Disease in Patients With Active Pulmonary Tuberculosis (TB-LUNG)

HIV/AIDS | TB - Tuberculosis

South Africa
Helse Nord-Trøndelag HF
Haukeland University Hospital; Addis Ababa University

Recruiting

The Clinical Influence of Developing a Sustainable Cardiac Surgery Service to Reduce the Burden of Rheumatic Heart Disease in Sub-Saharan Africa (RHD-CaSS)

Rheumatic Heart Disease | Anticoagulant Adverse Reaction

Norway, Ethiopia
University of Cape Town

Recruiting

High vs. Standard Dose Rifampicin for Effusive Tuberculous Pericarditis (IMPI-3)

HIV Status | Tuberculous Pericarditis

South Africa
Assiut University

Recruiting

Prevalence of Rheumatic Heart Disease According to Revised Jones Criteria (2015) in Assiut Governate

Rheumatic Fever

Egypt
University of Oxford

Enrolling by invitation

Immunogenicity of COVID-19 Vaccines in Tuberculosis Patients (CVTB)

Tuberculosis | Covid-19 Pandemics

Thailand
University of Washington
National Heart, Lung, and Blood Institute (NHLBI); Manmohan Cardiothoracic...

Active, not recruiting

Role of Statins In Slowing Rheumatic Heart Disease (RHD) Progression

Rheumatic Heart Disease | Valvular Disease

Nepal
Medecins Sans Frontieres, Netherlands
London School of Hygiene and Tropical Medicine; University College, London; University... and other collaborators

Active, not recruiting

PRACTECAL-PKPD Sub Study (PRACTECAL-PKPD)

Multi-drug Resistant Tuberculosis | Pulmonary Tuberculosis | Extensively Drug-Resistant Tuberculosis

Belarus, South Africa
University of Turin, Italy

Unknown

TLR Polymorphism, ASO and Beta-hemolytic Group A Streptococcus Infections in ADHD: an Observational Study (TLR;)

Attention Deficit-Hyperactivity Disorder

Italy
GlaxoSmithKline

Completed

Evaluate Safety and Immunogenicity of a Booster Dose of Pneumococcal Conjugate Vaccine in Preterm Born Infants.

Streptococcus Pneumoniae Vaccines | Infections, Streptococcal

Spain, Greece
National Institute of Allergy and Infectious Diseases...

Completed

Surveillance of Streptococcal Infections in Children in India

Group A Beta Hemolytic Streptococcal (GAS) Infection

India
GlaxoSmithKline

Completed

Immunogenicity and Safety Study of GlaxoSmithKline (GSK) Biologicals' Pneumococcal Vaccine (Synflorix™) When Administered to Children Who Are at an Increased Risk of Pneumococcal Infection

Streptococcus Pneumoniae Vaccines | Infections, Streptococcal

Russian Federation, Poland
Washington University School of Medicine

Completed

The Natural History of Community-Associated MRSA Infections and Decolonization Strategies (StLStaRS)

Furunculosis | Staphylococcus Aureus | Staphylococcal Skin Infections | Abscesses

United States
University of Tromso

Completed

Oral Health Literacy Tailored Communication

Periodontal Diseases | Streptococcal Infections | Dental Plaque | Sialorrhea | Dental Calculus | Lactobacillus Infection

Norway
University of Siena
Ministry of Education, Universities and Research, Italy

Completed

Serological Response to Antipneumococcal Vaccination and Impact on Streptococcus Pneumoniae Nasal Carriage in HIV Adults (PCV13HIV2011)

HIV Infection | Pneumococcal Infections

Italy
National Taiwan University Hospital

Completed

Surveillance and Follow-up for Latent Tuberculosis Infection and Risk of Developing Active Tuberculosis in Patients Receiving Long-term Dialysis

To Predict the Potential of Development of Active Tuberculosis in Those Receiving Long-term Dialysis by Using Interferon-gamma Release Assy

Taiwan
Brooke Army Medical Center
GlaxoSmithKline; Becton, Dickinson and Company

Completed

An Attempt to Reduce Community-Acquired Methicillin-Resistant Staphylococcus Aureus (MRSA) Infection in Soldiers

Cellulitis | Folliculitis | Abscesses | Community-Acquired MRSA Infections

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Evaluation of a Once Per Day Regimen of Accelerated Partial Breast Irradiation for Improved Breast Appearance in Patients With Low Risk, Hormone Responsive Breast Cancer

Anatomic Stage IA Breast Cancer AJCC v8 | Anatomic Stage 0 Breast Cancer AJCC v8 | HER2-Negative Breast Carcinoma | Estrogen Receptor-Positive Breast Carcinoma

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

ABL001 for the Treatment of Chronic Myeloid Leukemia in Patients Who Are on Therapy With Tyrosine Kinase Inhibitor

Philadelphia Chromosome Negative, BCR-ABL1 Positive Chronic Myelogenous Leukemia

United States
M.D. Anderson Cancer Center

Withdrawn

Immunotherapy (NHS-IL12 & Bintrafusp Alfa) and Radiation Therapy for the Treatment of Hormone Receptor Positive, HER2 Negative Metastatic Breast Cancer, the REINA Trial

Anatomic Stage IV Breast Cancer AJCC v8 | Prognostic Stage IV Breast Cancer AJCC v8 | Metastatic Breast Carcinoma | Hormone Receptor Positive Breast Adenocarcinoma | Metastatic HER2 Negative Breast Adenocarcinoma

United States

Clinical Trials on Gram Negative Meningitis

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in United States

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations