Clinical Trials on Head and Neck Squamous Cell Carcinoma (HNSCC)

Total 17243 results

Oncoethix GmbH

Completed

A Dose-Finding Study of Birabresib (MK-8628), a Small Molecule Inhibitor of the Bromodomain and Extra-Terminal (BET) Proteins, in Adults With Selected Advanced Solid Tumors (MK-8628-003)

Triple Negative Breast Cancer | Pancreatic Ductal Adenocarcinoma | Castrate-resistant Prostate Cancer | CRPC | NUT Midline Carcinoma | Non-small Cell Lung Cancer With Rearranged ALK Gene/Fusion Protein or KRAS Mutation
National Cancer Institute (NCI)

Active, not recruiting

Olaparib in Treating Patients With Advanced Glioma, Cholangiocarcinoma, or Solid Tumors With IDH1 or IDH2 Mutations

Glioblastoma | WHO Grade 3 Glioma | Advanced Malignant Solid Neoplasm | Recurrent Malignant Solid Neoplasm | Recurrent Glioma | Recurrent Cholangiocarcinoma | WHO Grade 2 Glioma

United States
Mansoura University

Completed

Enteropathogenic Escherichia Coli (EPEC): Does it Have a Role in Colorectal Tumourigenesis? (EPEC)

Colorectal Carcinoma | Enteropathogenic Escherichia Coli .

Egypt
National Cancer Institute (NCI)
Gynecologic Oncology Group

Completed

Carboplatin and Paclitaxel With or Without Bevacizumab Compared to Docetaxel, Carboplatin, and Paclitaxel in Treating Patients With Stage II, Stage III, or Stage IV Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cavity Carcinoma (Cancer)

Fallopian Tube Cancer | Ovarian Clear Cell Cystadenocarcinoma | Ovarian Endometrioid Adenocarcinoma | Ovarian Serous Cystadenocarcinoma | Stage IV Ovarian Epithelial Cancer | Primary Peritoneal Cavity Cancer | Brenner Tumor | Stage II Ovarian Epithelial Cancer | Stage III Ovarian Epithelial Cancer | Ovarian... and other conditions

United States
University of Kansas Medical Center

Recruiting

Comparing Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy (CRS-HIPEC) Using Mitomycin-C Versus Melphalan for Colorectal Peritoneal Carcinomatosis

ColoRectal Cancer | Cancer, Appendiceal

United States
Seattle Children's Hospital

Recruiting

EGFR806 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults

Soft Tissue Sarcoma | Carcinoma | Osteosarcoma | Ewing Sarcoma | Rhabdoid Tumor | Neuroblastoma | Retinoblastoma | Rhabdomyosarcoma | Wilms Tumor | Hepatoblastoma | Synovial Sarcoma | Desmoplastic Small Round Cell Tumor | Germ Cell Tumor | Pediatric Solid Tumor | Clear Cell Sarcoma | Malignant Peripheral Nerve Sheath Tumors

United States
Syndax Pharmaceuticals
Merck Sharp & Dohme LLC

Completed

Continuation Study of Entinostat in Combination With Pembrolizumab in Patients With Advanced Solid Tumors

Neoplasms | Neoplasms by Histologic Type | Lung Diseases | Neoplasms, Glandular and Epithelial | Digestive System Neoplasms | Endocrine Gland Neoplasms | Breast Diseases | Carcinoma, Non-Small-Cell Lung | Lung Neoplasms | Respiratory Tract Neoplasms | Thoracic Neoplasms | Bronchial Neoplasms | Solid Tumors | Renal...

United States
National Cancer Institute (NCI)

Terminated

Akt Inhibitor MK2206, Lapatinib Ditosylate, and Trastuzumab in Treating Patients With Locally Advanced or Metastatic HER2-Positive Breast , Gastric, or Gastroesophageal Cancer That Cannot Be Removed By Surgery

HER2-positive Breast Cancer | Male Breast Cancer | Stage IV Breast Cancer | Stage IIIC Breast Cancer | Adenocarcinoma of the Gastroesophageal Junction | Recurrent Breast Cancer | Stage IV Gastric Cancer | Recurrent Gastric Cancer | Recurrent Esophageal Cancer | Stage IV Esophageal Cancer | Stage IIIC Gastric... and other conditions

United States
Eisai Inc.

Completed

A Study of ZYC300 Administered With Cyclophosphamide Pre-Dosing

Breast Cancer | Ovarian Cancer | Prostate Cancer | Colon Cancer | Renal Cancer

United States
Nagla Abdel Karim

Completed

Bosutinib in Combination With Pemetrexed in Patients With Selected Metastatic Solid Tumors

Carcinoma, Non-Small-Cell Lung | Ovarian Cancer | Thymoma | Mesothelioma | Bladder Cancer | Peritoneal Cancer | Thymus Cancer | Uterine Cervical Cancer

United States
Seattle Children's Hospital

Active, not recruiting

B7H3 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults

Melanoma | Soft Tissue Sarcoma | Carcinoma | Osteosarcoma | Ewing Sarcoma | Rhabdoid Tumor | Neuroblastoma | Retinoblastoma | Rhabdomyosarcoma | Wilms Tumor | Hepatoblastoma | Synovial Sarcoma | Desmoplastic Small Round Cell Tumor | Germ Cell Tumor | Pediatric Solid Tumor | Clear Cell Sarcoma | Malignant Peripheral Nerve Sheath...

United States
Genmab

Recruiting

GEN1047 for Solid Tumors - First in Human (FIH) Trial

Squamous Non Small Cell Lung Cancer (NSCLC-SCC) | Breast Cancer, Breast Neoplasms | Endometrial Cancer, Endometrial Neoplasm | Ovarian Cancer, Ovarian Neoplasms

United States, France, Spain, Netherlands, Belgium, United Kingdom, Denmark, Italy, Poland
GlaxoSmithKline

Completed

Cancer in Patients With Gabapentin (GPRD)

Epilepsy | Renal Cell Carcinoma | Diabetes | Stomach Cancer | Cancer | Breast Cancer | Pancreatic Cancer | Bladder Cancer | Chronic Pancreatitis | Renal Cancer | Anal Cancer | Renal Pelvis Cancer | Pain, Neuropathic | Nervous System Cancer | Penis Cancer | Bone and Joint Cancer
Syndax Pharmaceuticals

Completed

Cardiac Safety Study of Entinostat in Men and Women With Advanced Solid Tumors

Neoplasms | Neoplasms by Histologic Type | Lung Diseases | Neoplasms, Glandular and Epithelial | Digestive System Neoplasms | Endocrine Gland Neoplasms | Breast Neoplasms | Breast Diseases | Carcinoma, Non-Small-Cell Lung | Lung Neoplasms | Respiratory Tract Neoplasms | Thoracic Neoplasms | Bronchial Neoplasms | Solid... and other conditions

United States
AIDS Malignancy Consortium
National Cancer Institute (NCI)

Completed

Anal HPV Tests in Screening for Cell Changes in the Anus in Patients With HIV

HIV Infection | Anal Cancer | Human Papilloma Virus Infection

United States, Puerto Rico
National Cancer Institute (NCI)

Withdrawn

Selumetinib and Akt Inhibitor MK-2206 in Treating Patients With Refractory or Advanced Gallbladder or Bile Duct Cancer That Cannot Be Removed By Surgery

Advanced Adult Primary Liver Cancer | Localized Unresectable Adult Primary Liver Cancer | Recurrent Adult Primary Liver Cancer | Recurrent Extrahepatic Bile Duct Cancer | Unresectable Extrahepatic Bile Duct Cancer | Stage II Gallbladder Cancer | Stage IIIA Gallbladder Cancer | Stage IIIB Gallbladder... and other conditions
Fred Hutchinson Cancer Center
Amazon.com Services LLC

Recruiting

Personalized Neo-Antigen Peptide Vaccine for the Treatment of Stage IIIC-IV Melanoma or Hormone Receptor Positive Her2 Negative Metastatic Refractory Breast Cancer

Anatomic Stage IV Breast Cancer AJCC v8 | Prognostic Stage IV Breast Cancer AJCC v8 | Metastatic Cutaneous Melanoma | Unresectable Cutaneous Melanoma | Clinical Stage III Cutaneous Melanoma AJCC v8 | Pathologic Stage IIIC Cutaneous Melanoma AJCC v8 | Pathologic Stage IIID Cutaneous Melanoma AJCC... and other conditions

United States
Maastricht University Medical Center

Recruiting

Qualitative Study in Patients With Genodermatoses and Healthcare Professionals on Reproductive Counselling

Quality of Life | Tuberous Sclerosis | Basal Cell Nevus Syndrome | Cutis Laxa | Epidermolysis Bullosa | Ichthyosis | Ectodermal Dysplasia | Albinism | Birt-Hogg-Dube Syndrome | Palmoplantar Keratoses

Netherlands
ANRS, Emerging Infectious Diseases
University Hospital, Geneva; University of Bordeaux; International Agency for... and other collaborators

Recruiting

Evaluation of Triage Options After HPV Testing for Cervical Cancer Screening Among HIV-infected Women (AIMA-CC)

HIV Infections | HPV - Anogenital Human Papilloma Virus Infection

Burkina Faso, Cambodia, Côte D'Ivoire
Barts & The London NHS Trust
Royal Marsden NHS Foundation Trust; Guy's and St Thomas' NHS Foundation Trust; Case Western Reserve University and other collaborators

Completed

Diagnostic Accuracy of MRI, DWI MRI, FDG-PET/CT and FEC PET/CT in the Detection of Lymph Node Metastases in Surgically Staged Endometrial and Cervical Carcinoma (MAPPING)

Endometrial Cancer | Surgically Staged Endometrial and Cervical Carcinoma | Cervical Cancer: Invasive Disease, FIGO Stage 1B1 or Higher | Stage 1A With Myometrial Invasion or Any Higher Stage and Grade 3 | Stage 1A With Myometrial Invasion or Any Other Higher Stage and Serous Papillary or... and other conditions

United Kingdom
National Cancer Institute (NCI)

Completed

Erlotinib Plus Carboplatin and Paclitaxel in Ovarian Carcinoma

Fallopian Tube Cancer | Ovarian Clear Cell Cystadenocarcinoma | Ovarian Endometrioid Adenocarcinoma | Ovarian Serous Cystadenocarcinoma | Stage IV Ovarian Epithelial Cancer | Brenner Tumor | Stage III Ovarian Epithelial Cancer | Ovarian Mucinous Cystadenocarcinoma | Ovarian Undifferentiated Adenocarcinoma

United States
Universitaire Ziekenhuizen KU Leuven

Recruiting

Register With Patients in Which Hyperthermic Intra-Peritoneal Chemotherapy (HIPEC) Was Performed (HIPEC)

Pseudomyxoma Peritonei | Peritoneal Carcinomatosis | Peritoneal Mesothelioma

Belgium
GOG Foundation
National Cancer Institute (NCI)

Completed

Dactinomycin or Methotrexate in Treating Patients With Low-Risk Gestational Trophoblastic Neoplasia

Hydatidiform Mole | Choriocarcinoma | FIGO Stage I Gestational Trophoblastic Tumor | FIGO Stage II Gestational Trophoblastic Tumor | FIGO Stage III Gestational Trophoblastic Tumor

United States, Korea, Republic of, Canada, Japan, United Kingdom
Singapore General Hospital

Unknown

Evaluation of Safety and Feasibility of EUS-guided RFA for Solid Pancreatic Neoplasms

Pancreatic Neoplasms | Pancreatic Cancer | Pancreatic Adenocarcinoma | Pancreatic Ductal Adenocarcinoma | Pancreatic Neuroendocrine Tumor

Singapore
Novartis Pharmaceuticals

Recruiting

Study of [68Ga]-FF58 in Patients With Selected Solid Tumors Expected to Overexpress αvβ3 and αvβ5 Integrins.

Brain Neoplasms | Glioblastoma Multiforme | Gastroesophageal Adenocarcinoma | Pancreatic Ductal Adenocarcinoma

Germany, United States, France
Children's Oncology Group
National Cancer Institute (NCI)

Recruiting

Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors

Melanoma | Neuroblastoma | Pancreatic Ductal Adenocarcinoma | Refractory Malignant Solid Neoplasm | Endometrial Carcinoma | Recurrent Ewing Sarcoma | Recurrent Hepatoblastoma | Recurrent Malignant Solid Neoplasm | Recurrent Non-Hodgkin Lymphoma | Recurrent Osteosarcoma | Refractory Ewing Sarcoma | Refractory... and other conditions

United States
Maastricht University Medical Center

Enrolling by invitation

Reproductive Options in Inherited Skin Diseases (REPRO-ISD)

Tuberous Sclerosis | Basal Cell Nevus Syndrome | Cutis Laxa | Epidermolysis Bullosa | Ichthyosis | Ectodermal Dysplasia | Albinism | Xeroderma Pigmentosum | Birt-Hogg-Dube Syndrome | Palmoplantar Keratoses

Netherlands
University Health Network, Toronto
Princess Margaret Hospital, Canada; Ontario Institute for Cancer Research; Terry...

Recruiting

Marathon of Hope Cancer Centres Network Study for Ontario (MOHCCN-O)

Melanoma | Lymphoma | Kidney Cancer | Leukemia | Breast Cancer | Head and Neck Cancer | Colorectal Cancer | Lung Cancer | Solid Tumor | Prostate Cancer | Pancreas Cancer | Ovary Cancer

Canada
Inova Health Care Services
University of Houston; University of Louisville; Howard University; Tigerlily Foundation and other collaborators

Active, not recruiting

Mind Over Matter for Black and African American Women: A Single Arm Trial Examining Feasibility and Acceptability of a Supportive Intervention (MOM)

Melanoma | Cancer | Breast Cancer | Head and Neck Cancer | Gynecologic Cancer | Colorectal Cancer | Esophageal Cancer | Lung Cancer | Brain Cancer | Gastrointestinal Cancer | Central Nervous System Cancer | Acceptance and Commitment Therapy | Blood Cancer | Genitourinary Cancer | Psychosocial Intervention | Mind-Body Therapies

United States
Postgraduate Institute of Medical Education and...

Completed

Vitamin Supplementation in NSCLC Patients on Pemetrexed Based Chemotherapy (PEMVITASTART)

Anemia | Thrombocytopenia | Neutropenia | Lung Adenocarcinoma | Nonsquamous Nonsmall Cell Neoplasm of Lung

India
M.D. Anderson Cancer Center
AstraZeneca

Active, not recruiting

Selumetinib and Olaparib in Solid Tumors

Malignant Neoplasms of Female Genital Organs | Malignant Neoplasm of Breast | Malignant Neoplasms of Thyroid and Other Endocrine Glands | Malignant Neoplasms of Digestive Organs | Malignant Neoplasms of Male Genital Organs

United States
University of Utah
National Cancer Institute (NCI)

Completed

Exercise in Improving Mobility and Reducing Fatigue and/or Weakness in Older Cancer Survivors

Lymphoma | Breast Cancer | Fatigue | Colorectal Cancer | Esophageal Cancer | Ovarian Cancer | Lung Cancer | Prostate Cancer | Bladder Cancer

United States
University of Washington
National Cancer Institute (NCI)

Completed

Vaccine Therapy in Treating Patients With Stage IV HLA-A2 and HER2 Positive Breast or Ovarian Cancer Receiving Trastuzumab

Stage IV Breast Cancer | HER2/Neu Positive | HLA-A2 Positive Cells Present | Stage IV Ovarian Cancer

United States
University of Pisa

Unknown

Study on the Incidence of Febrile Episodes During Stem Cells Collection After Chemotherapy in Patients With Multiple Myeloma

G-CSF, Multiple Myeloma, Febrile Episode, Filgrastim, Leograstim
Giselle Sholler
Translational Genomics Research Institute; Dell, Inc.

Completed

Molecular-Guided Therapy for Childhood Cancer

Glioma | Renal Cell Carcinoma | Osteosarcoma | Ependymoma | Medulloblastoma | Neuroblastoma | Meningioma | Craniopharyngioma | Choroid Plexus Neoplasms | Rhabdomyosarcoma | Wilms Tumor | Ewings Sarcoma | Malignant Rhabdoid Tumor | Liver Tumors | Germ Cell Tumors | Dysembryoplastic Neuroepithelial Tumor | Clear Cell Sarcoma | ... and other conditions

United States, Lebanon
Tata Medical Center

Completed

Dose Escalation Versus Standard in Laryngopharyngeal Cancers (INTELHOPE)

Malignant Neoplasm of Oropharynx Stage III | Malignant Neoplasm of Larynx Stage III | Malignant Neoplasm of Hypopharynx Stage III | Malignant Neoplasm of Oropharynx Stage IVa | Malignant Neoplasm of Oropharynx Stage IVb | Malignant Neoplasm of Larynx Stage IV | Malignant Neoplasm of Hypopharynx... and other conditions

India
National Cancer Institute (NCI)

Terminated

Veliparib, Oxaliplatin, and Capecitabine in Treating Patients With Advanced Solid Tumors

Unspecified Adult Solid Tumor, Protocol Specific | Adenocarcinoma of the Pancreas | Recurrent Pancreatic Cancer | Stage IV Pancreatic Cancer | Stage IV Breast Cancer | Stage IV Ovarian Epithelial Cancer | Stage IV Ovarian Germ Cell Tumor | Stage II Breast Cancer | Stage IIIA Breast Cancer | Stage IIIB... and other conditions

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

IRX-2, Cyclophosphamide, and Pembrolizumab in Treating Participants With Recurrent or Metastatic Gastric or Gastroesophageal Junction Cancer

Clinical Stage IV Gastric Cancer AJCC v8 | Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8 | Metastatic Gastric Adenocarcinoma | Metastatic Gastroesophageal Junction Adenocarcinoma | Postneoadjuvant Therapy Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8 | Postneoadjuvant... and other conditions

United States
Laval University

Recruiting

Diagnostic Value of DWI-MRI for Detection of Peritoneal Metastases in High-risk Pancreatic Ductal Adenocarcinoma. (DWI-PDAC)

Pancreas Adenocarcinoma | Pancreas Cancer, Duct Cell Adenocarcinoma | Peritoneal Carcinomatosis | Peritoneal Metastases

Canada
NRG Oncology
National Cancer Institute (NCI)

Active, not recruiting

Ruxolitinib Phosphate, Paclitaxel, and Carboplatin in Treating Patients With Stage III-IV Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Ovarian Endometrioid Adenocarcinoma | Ovarian Clear Cell Adenocarcinoma | Primary Peritoneal High Grade Serous Adenocarcinoma | Fallopian Tube Clear Cell Adenocarcinoma | Fallopian Tube Endometrioid Adenocarcinoma | Stage III Fallopian Tube Cancer AJCC v7 | Stage III Primary Peritoneal Cancer... and other conditions

United States
National Cancer Institute (NCI)

Completed

Pazopanib Hydrochloride in Treating Young Patients With Solid Tumors That Have Relapsed or Not Responded to Treatment

Unspecified Childhood Solid Tumor, Protocol Specific | Recurrent Childhood Soft Tissue Sarcoma | Recurrent Childhood Brain Stem Glioma | Recurrent Childhood Visual Pathway Glioma | Childhood Central Nervous System Germ Cell Tumor | Childhood Central Nervous System Choriocarcinoma | Childhood Central... and other conditions

United States
xiang yang

Recruiting

Biweekly Actinomycin-D Treatment or Multi-day Methotrexate Protocol in Low-risk Gestational Trophoblastic Neoplasia

Gestational Trophoblastic Tumor | Gestational Trophoblastic Neoplasia | Choriocarcinoma | Stage I Gestational Trophoblastic Tumor | Stage II Gestational Trophoblastic Tumor | Stage III Gestational Trophoblastic Tumor | Invasive Mole

China
Cancer Research UK
Heptares Therapeutics Limited

Recruiting

HTL0039732 in Participants With Advanced Solid Tumours

Sarcoma | Neoplasms | Kidney Neoplasms | Uterine Cervical Neoplasms | Stomach Neoplasms | Head and Neck Neoplasms | Lung Neoplasms | Urinary Bladder Neoplasms | Colorectal Neoplasms | Pancreatic Neoplasms | Esophageal Neoplasms | Mesothelioma, Malignant | Prostatic Neoplasms, Castration-Resistant | Pheochromocytomas

United Kingdom
Dana-Farber Cancer Institute
Siemens Medical Solutions

Recruiting

A Novel Imaging Protocol in Use to Identify Lymph Nodes and Organs of Interest

Kidney Cancer | Urologic Neoplasms | Prostate Cancer | Bladder Cancer | Urethral Cancer | Penile Cancer | Urologic Cancer | Testicular Cancer

United States
Seagen Inc.

Active, not recruiting

Basket Study of Tucatinib and Trastuzumab in Solid Tumors With HER2 Alterations

Urologic Neoplasms | Uterine Cervical Neoplasms | Uterine Neoplasms | Carcinoma, Non-Small-Cell Lung | Biliary Tract Neoplasms | HER2 Mutations Breast Neoplasms

United States, United Kingdom, Spain, Korea, Republic of, Italy, Belgium, Germany, Japan, Netherlands, Poland
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Nivolumab, Ipilimumab and Chemoradiation in Treating Patients With Resectable Gastric Cancer

Gastric Adenocarcinoma | Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8 | Clinical Stage 0 Gastric Cancer AJCC v8 | Clinical Stage I Gastric Cancer AJCC v8 | Clinical Stage IIB Gastric Cancer AJCC v8 | Clinical Stage IVA Gastric Cancer AJCC v8 | Pathologic Stage 0 Gastric... and other conditions

United States
Kirby Institute
National Institute of Allergy and Infectious Diseases (NIAID); ViiV Healthcare and other collaborators

Withdrawn

Inflammation and Co-Infections in D²EFT (i2-D²EFT)

Cytomegalovirus Infections | Human Papilloma Virus | HIV-infection/Aids | Human Herpesvirus 4 Infections | Human Herpesvirus 8 Infection
Teal Health, Inc.

Active, not recruiting

Development of a Self-collection Device for Cervical Cancer Screening

Human Papilloma Virus | Human Papilloma Virus Infection Type 16 | Human Papilloma Virus Infection Type 18

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Paclitaxel for the Treatment of Gastric or Gastroesophageal Cancer

Peritoneal Carcinomatosis | Clinical Stage IV Gastric Cancer AJCC v8 | Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8 | Metastatic Gastric Adenocarcinoma | Metastatic Gastroesophageal Junction Adenocarcinoma | Postneoadjuvant Therapy Stage IV Gastroesophageal Junction Adenocarcinoma... and other conditions

United States
Roswell Park Cancer Institute
National Cancer Institute (NCI)

Active, not recruiting

Gene-Modified T Cells With or Without Decitabine in Treating Patients With Advanced Malignancies Expressing NY-ESO-1

Metastatic Melanoma | Advanced Malignant Solid Neoplasm | Unresectable Melanoma | Clinical Stage III Cutaneous Melanoma AJCC v8 | Pathologic Stage IIIB Cutaneous Melanoma AJCC v8 | Pathologic Stage IIIC Cutaneous Melanoma AJCC v8 | Pathologic Stage IIID Cutaneous Melanoma AJCC v8 | Pathologic Stage... and other conditions

United States

Clinical Trials on Head and Neck Squamous Cell Carcinoma (HNSCC)

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Malta

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations