Clinical Trials on Health Promotion and Obesity Prevention in South Africa

Total 3125 results

Amsterdam UMC, location VUmc
Syddansk Universitet, Denmark; Stichting Alexander (the Netherlands); Aalborg... and other collaborators

Recruiting

YoPA - A Youth-centred Participatory Action (YoPA)

Physical Activity | Sleep | Health Promotion

Denmark, South Africa, Netherlands, Nigeria
University of KwaZulu
University of California, San Francisco; Centers for Disease Control and Prevention and other collaborators

Completed

Effectiveness of an HIV-adapted IMCI Training and Supervision Programme for Community Health Workers

Infant Feeding Practices | Prevention of Mother-to-child Transmission of HIV | Antenatal Health Care Utilization | Postnatal Health Care Utilization

South Africa
Brown University

Completed

Schools Championing Safe South Africa

Prevention or Reduction of HIV Risk Behavior | Prevention or Reduction of Intimate Partner Violence

South Africa
Medical College of Wisconsin
National Institute of Mental Health (NIMH)

Completed

Experimental Analysis of HIV Risk Assessment Reactivity in South African Clinics

HIV Prevention and Assessment Reactivity

South Africa
Wits RHI Research Centre Clinical Research Site
University of Alabama at Birmingham; University of California, San Francisco

Recruiting

PrEP Restart for Adolescent Girls and Young Women Using STI Self Testing and Assessment of Risk (PALESA)

HIV Prevention

South Africa
Harokopio University

Completed

Multi-component, Kindergarten-based, Family-involved Intervention for the Prevention of Childhood Obesity:The ToyBox-study

Prevention of Childhood Obesity

Greece
Massachusetts General Hospital
National Institute of Mental Health (NIMH); National Institutes of Health (NIH) and other collaborators

Completed

Safer Conception for Women - Understanding Use of Periconception PrEP

HIV Prevention | Conception

South Africa
North-West University, South Africa
Medical Research Council, South Africa; National Research Foundation of South...

Active, not recruiting

Exercise, Arterial Modulation and Nutrition in Youth South Africa Study (ExAMIN-Youth)

Hypertension | Childhood Obesity | Retinal Artery Stenosis

South Africa
Columbia University
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

Obesogenic Origins of Maternal and Child Metabolic Health Involving Dolutegravir (ORCHID)

Obesity | HIV | Maternal Obesity During Childbirth | Maternal Obesity Complicating Pregnancy | Obesity, Infant

South Africa
Prof Mags Beksinska

Completed

Comparative Study of the Contraceptive Efficacy of the Cupid, Cupid 2 and FC2 Female Condom

Pregnancy Prevention

South Africa
University of Pretoria

Not yet recruiting

Kefazolin Versus Kefazolin Plus Metronidazole to Reduce Postpartum Infection

Prevention of Postpartum Sepsis

South Africa
University of South Carolina
National Institute of Nursing Research (NINR)

Recruiting

Connect Through PLAY: A Staff-based Physical Activity Intervention for Middle School Youth (Connect)

Physical Activity | Obesity Prevention

United States
Centre for the AIDS Programme of Research in South...
Johns Hopkins University; National Institute of Allergy and Infectious Diseases...

Completed

STI Care Model to Reduce Genital Inflammation and HIV Risk in South African Women

Sexually Transmitted Diseases | HIV Prevention

South Africa
University of Pretoria

Completed

A Randomized Trial Comparing Oxytocin and Oxytocin + Ergometrine for Prevention of Postpartum Haemorrhage at Caesarean Section

Prevention of Post Partum Haemorrhage

South Africa
Swiss Federal Institute of Technology
North-West University, South Africa

Completed

Omega-3 Fatty Acid Supplementation and Fractional Iron Absorption in Obese South African Women

Obesity

South Africa
University of Pretoria

Completed

Efficacy of Using a Closing Pack to Reduce Postpartum Sepsis

Prevention of Postpartum Sepsis

South Africa
University of Cape Town

Completed

Impact of Employee Wellness Programme

Obesity

South Africa
University of Cape Town

Unknown

Pregnancy-Related Obesity Prevention Through Education & Communication Technology in AFRICA:The PROTECT-AFRICA STUDY (PROTECT-AFRI)

Obesity

South Africa
University of Witwatersrand, South Africa
UNITAID

Completed

CHARACTERISE - A Cross-sectional, Observational Study to Characterise the Transition to Dolutegravir-based Regimens in South Africa in Terms of the Emergence of Obesity, Viral Re-suppression and Integration Into Routine Programme Care (CHARACTERISE)

Dolutegravir

South Africa
Johns Hopkins University
Aurum Institute; UNITAID; KNCV Tuberculosis Foundation

Completed

Qualitative Understanding of Community TB Services Pre and Post the CHIP-TB Trial

Tuberculosis Infection | Tuberculosis Prevention

Ethiopia, South Africa
University of Witwatersrand, South Africa
National Institute of Allergy and Infectious Diseases (NIAID); University of... and other collaborators

Completed

Effectiveness of a Pre-adolescent Inter-generational Intervention to Address HIV and Obesity

Obesity | Hiv

South Africa
Africa Health Research Institute

Completed

Isisekelo Sempilo Trial to Optimize Peer (Thetha Nami) Delivery of HIV Prevention to Young People in Rural KwaZulu-Natal

HIV Prevention

South Africa
University of Cape Town

Completed

The Impact of Obesity on Cardiac Function in Pregnancy (CFOP)

Obesity | Pregnancy

South Africa
Immtech Pharmaceuticals, Inc

Terminated

Randomized, Double-Blind Phase 1 Safety and Tolerability Study of Pafuramidine Maleate (DB289) in Healthy Subjects

Healthy

South Africa
Lyndra Inc.

Completed

Study to Evaluate Safety/Duration in Stomach of Extended Release Capsules in Healthy Adults

Healthy | Gastric Retention

Australia
North-West University, South Africa
GlaxoSmithKline; Novartis; Pfizer; Boehringer Ingelheim; Medical Research Council; Medical... and other collaborators

Active, not recruiting

The African-PREDICT Study (PREDICT)

Cardiovascular Diseases | Hypertension | Health Risk Behaviors | Arterial Stiffness | Young | Renin Hypertension

South Africa
Boehringer Ingelheim

Completed

To Determine Blood Concentrations of Ibuprofen and Caffeine in a Tablet Against Ibuprofen Alone From Another Tablet

Healthy

South Africa
Medical University of South Carolina
National Institute on Drug Abuse (NIDA); National Institutes of Health (NIH); University of Minnesota

Recruiting

Impact of Cigarette and E-cigarette Menthol Regulation on Current Smokers of Menthol Cigarettes

Smoking Prevention and Control

United States
North-West University, South Africa
University of Zurich; University of Cape Town; Medical Research Council, South... and other collaborators

Recruiting

National Blood Pressure Screening in Children to Improve Paediatric Healthcare in South Africa

Hypertension | Obesity, Childhood | Obesity, Adolescent

South Africa, Switzerland
Novo Nordisk A/S

Completed

Bioequivalence of Two Formulations of Biphasic Insulin Aspart 70 in Healthy Male Subjects

Healthy | Diabetes

South Africa
Novo Nordisk A/S

Completed

Comparison of Two Insulin Aspart Formulations in Healthy Volunteers

Healthy | Diabetes

South Africa
Novo Nordisk A/S

Completed

Bioequivalence of Two Formulations of Biphasic Insulin Aspart 50 in Healthy Male Subjects

Healthy | Diabetes

South Africa
University of Maryland, College Park
National Institute on Drug Abuse (NIDA); Medical Research Council, South Africa

Active, not recruiting

Siyakhana Peer: Evaluating a Peer Recovery Coach Model to Reduce Substance Use Stigma in South African HIV Care

Substance-Related Disorders | HIV | Substance Use | Substance Use Disorders | Treatment Adherence | Treatment Adherence and Compliance | Stigmatization | Delivery of Health Care | Stigma, Social | Attitude of Health Personnel | Community Health Workers | Health Personnel | Health Personnel Attitude | Health Care Seeking... and other conditions

South Africa
University of Pennsylvania

Withdrawn

Vitality Health Incentives for Physical Activity

Obesity

United States, South Africa
FHI 360
United States Agency for International Development (USAID); Jhpiego; Wits Reproductive... and other collaborators

Recruiting

The CATALYST Study

HIV Prevention

Kenya, Lesotho, South Africa, Uganda, Zimbabwe
University of Witwatersrand, South Africa

Completed

Epidemiology of Congenital Cytomegalovirus in a High HIV Prevalence Setting, South Africa

Neurodevelopmental Disorders | Hearing Loss | Immunogenicity | Stillbirth | Neonatal Death | Cytomegalovirus Congenital

South Africa
HIV Vaccine Trials Network
South Africa AIDS Vaccine Initiative

Completed

Safety of and Immune Response to a DNA HIV Vaccine Boosted With a Modified Vaccinia HIV Vaccine and Protein HIV Vaccine in Healthy Adults

HIV Seronegativity | HIV Preventive Vaccine

South Africa
Alvotech Swiss AG

Active, not recruiting

AVT03 With Xgeva in Healthy Male Subjects

This is a Phase Study Conducted in Healthy Volunteers

South Africa
GlaxoSmithKline

Completed

Study to Determine the Bioequivalence of Two Fixed Dose Combination (FDC) Tablet Formulations of Amlodipine and Losartan FDC5/50 and FDC5/100 Under Fasting Conditions

Hypertension

South Africa
University of Witwatersrand, South Africa

Completed

Comparison Of Trabeculectomy Versus The Ex-PRESS Miniature Glaucoma Device In The Same Patient: A Prospective Randomized Study (XVT-USF)

Glaucoma

South Africa
University of Maryland, College Park
National Institute of Mental Health (NIMH); Medical Research Council, South...

Completed

Community Health Worker Training to Reduce Depression and Substance Use Stigma in TB/HIV Care in South Africa (Siyakhana)

Substance-Related Disorders | Depression | Tuberculosis | Hiv | Mental Health Disorder | Mental Disorder | Health Care Utilization | Treatment Adherence and Compliance | Social Stigma | Attitude of Health Personnel | Community Health Workers | Health Care Delivery

South Africa
GlaxoSmithKline

Completed

Bioequivalence Study Between GSK3542503 Hydrochlorothiazide + Amiloride Hydrochloride 50 mg: 5 mg Tablets and Reference Product in Healthy Adult Participants Under Fasting Conditions

Hypertension

South Africa
United States Department of Defense

Terminated

Preventing Health Damaging Behaviors in Male and Female Army Recruits

Sexually Transmitted Infection (STI) Prevention | Unintended Pregnancy Prevention | Sexual Risk Reduction | Alcohol and Other Substance Use Prevention | Intimate Partner Violence Prevention

United States
Statens Serum Institut
Bill and Melinda Gates Foundation; Aurum Institute; Leiden University Medical... and other collaborators

Recruiting

First-in-Human Trial of the Novel Tuberculosis Vaccine Candidate, H107e/CAF®10b (nTB-01)

Healthy

South Africa
Ocular Therapeutix, Inc.

Completed

Multi-Arm Feasibility Study Evaluating OTX-TP Compared to Timolol in Treatment of Subjects With Open Angle Glaucoma

Glaucoma

South Africa
University of Cape Town

Completed

Health System Dynamic & Resource Requirement in a South African COVID-19 Field Hospital

COVID-19 Pandemic | Low-Income Population | Global Health | Health Resources | Field Hospitals | Health Systems

South Africa
University of South Carolina

Completed

Sistas Inspiring Sistas Through Activity and Support (SISTAS)

Prevention Harmful Effects

United States
Loyola University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); University... and other collaborators

Withdrawn

Vitamin D Ancillary Study in 5 Populations of African Origin (VIDA)

Obesity | Cardiovascular Disease

South Africa, Jamaica, Ghana, United States, Seychelles
University of Cape Town
Bill and Melinda Gates Foundation

Unknown

The ASOS-2 Trial Maternal Mortality Sub-study

Cesarean Section | Maternal Mortality | Africa

South Africa
Catalyst Biosciences

Completed

Study of Next-Generation Recombinant Factor IX Variant in Adult Subjects With Hemophilia B

Hemophilia B

South Africa

Clinical Trials on Health Promotion and Obesity Prevention in South Africa

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Saint Lucia

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

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Locations