Clinical Trials on Healthcare-associated Infection in Australia

Total 1927 results

Bayside Health
Deakin University

Completed

Time Interval for Changing Closed System Suction Catheters, Effect on Ventilator Associated Pneumonia

Pneumonia, Ventilator Associated | Closed System Suction Catheter

Australia
Bayside Health
National Health and Medical Research Council, Australia

Recruiting

Tranexamic Acid to Reduce Infection After Gastrointestinal Surgery (TRIGS)

Bleeding | Anesthesia | Gastrointestinal Complication | Healthcare Associated Infection | Infection Wound

Australia
Valneva Austria GmbH

Completed

Study Assessing Immunogenicity and Safety of IC43 In Intensive Care Patients

Pneumonia, Ventilator-Associated

Austria
The George Institute
Sunnybrook Health Sciences Centre; Imperial College London

Completed

Selective Decontamination of the Digestive Tract in Intensive Care Unit Patients (SuDDICU)

Sepsis | Critical Illness | Septic Shock | Ventilator Associated Pneumonia

Australia, Canada, United Kingdom
Medical University of Vienna

Completed

Prophylaxis of Ventilator Associated Pneumonia by Continuous Lateral Rotation Therapy

Pneumonia, Ventilator-Associated

Austria
Cubist Pharmaceuticals LLC

Terminated

Study of Intravenous Ceftolozane/Tazobactam Compared to Piperacillin/Tazobactam in Ventilator-Associated Pneumonia

Ventilator-Associated Pneumonia (VAP)

United States, Australia, New Zealand
Melbourne Health

Completed

The Effect of Prophylactic Probiotic Lactobacilli in Enteral Feeding on Nosocomial Pneumonia Rates in Critically Ill Patients

Critical Illness

Australia
The University of Queensland
European Society of Intensive Care Medicine

Completed

International Study on NoSocomial Pneumonia in Intensive CaRE (PneumoINSPIRE) (PneumoINSPIRE)

Nosocomial Pneumonia

Australia, Greece
Johnson & Johnson Pharmaceutical Research & Development...

Terminated

To Compare Safety and Efficacy of Doripenem Versus Imipenem-Cilastatin in Patients With Ventilator-Associated Pneumonia

Ventilator-Associated Pneumonia

United States, Australia, Germany, France, Spain, Argentina, Mexico, Portugal, India, Romania, Turkey, Ukraine, Canada, Belgium, Brazil, Philippines, Russian Federation, Hungary, Israel, Thailand, Guatemala
Arsanis, Inc.

Terminated

Prevention of S. Aureus Pneumonia Study in Mechanically Ventilated Subjects Who Are Heavily Colonized With S. Aureus.

Pneumonia, Ventilator-associated | Pneumonia, Staphylococcal

United States, Spain, France, Czechia, Portugal, Israel, Romania, Russian Federation, Hungary, Poland, Ukraine, India, Austria, Georgia, Serbia, South Africa
Pfizer

Terminated

Study Evaluating Safety and Efficacy of Tigecycline Versus Imipenem/Cilastatin Subjects With Hospital-Acquired Pneumonia

Pneumonia, Bacterial

Canada, United States, Argentina, Australia, Brazil, Chile, Colombia, Croatia, France, Hungary, Korea, Republic of, Latvia, Russian Federation, Taiwan
St. Jude Children's Research Hospital

Completed

Ethanol Lock Therapy for Treatment and Secondary Prophylaxis of Central Line-Associated Bloodstream Infection

Central Line-Associated Bloodstream Infection

United States, Australia
MedImmune LLC
National Institute of Allergy and Infectious Diseases (NIAID); Antibacterial... and other collaborators

Completed

Effort to Prevent Nosocomial Pneumonia Caused by Pseudomonas Aeruginosa in Mechanically Ventilated Subjects (EVADE)

Pseudomonas Aeruginosa

Spain, United States, Belgium, France, Hungary, United Kingdom, Israel, Austria, Portugal, Greece, Czechia, Turkey, Croatia, Ireland
Menzies School of Health Research
Charles Darwin University; Northern Territory of Australia as represented by... and other collaborators

Recruiting

The Communicate Study Partnership

Aboriginal Health | Cultural Safety | Access to Interpreters | Healthcare Provider Training

Australia
Kirby Institute
Bristol-Myers Squibb; GlaxoSmithKline; Merck Sharp & Dohme LLC; Gilead Sciences; Hoffmann-La... and other collaborators

Terminated

Facial Lipoatrophy Trial: Immediate Versus Deferred Injections of Poly-L-Lactic Acid for HIV Facial Lipoatrophy

HIV Infections | HIV-Associated Lipodystrophy

Australia
Medical University of Vienna

Completed

Erythema at Exit Site & Tablet Camera

Digital Technology | CLABSI - Central Line Associated Bloodstream Infection | CRBSI - Catheter Related Bloodstream Infection

Austria
St Vincent's Hospital, Sydney

Unknown

Identification and Quantification of HIV CNS Latency Biomarkers

HIV | HIV-associated Neurocognitive Disorder (HAND)

Australia
Zydus Lifesciences Limited

Completed

A Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ZYIL1 in Subjects With Cryopyrin Associated Periodic Syndromes (CAPS)

Cryopyrin Associated Periodic Syndrome

Australia
Kirby Institute
Bristol-Myers Squibb; GlaxoSmithKline; Merck Sharp & Dohme LLC; Roche Pharma AG; Boehringer... and other collaborators

Completed

Can Resistance Enhance Selection of Treatment? (CREST)

HIV Infection

Australia
Inflazome UK Ltd

Completed

Safety and Tolerability, Pharmacokinetic and Pharmacodynamic Study With IZD334

Healthy Volunteers | Cryopyrin Associated Periodic Syndrome

Australia
Ark Biosciences Inc.

Terminated

A Study of AK0529 in Infants Hospitalized With RSV

Respiratory Syncytial Virus Infections

Australia
GlaxoSmithKline

Terminated

Evaluation of the Safety, Tolerability and Pharmacokinetics of Repeat Oral Doses of GSK580416

Infections, Bacterial | Bacterial Infection

Australia
Bayside Health
National Institutes of Health (NIH); Monash Medical Centre

Unknown

Innate Immunity in HIV Positive Patients Co-infected With Hepatitis C Virus (HCV) or Hepatitis B Virus (HBV)

HIV Infections | HIV-hepatitis Co-infection

Australia
Bayside Health
Gilead Sciences; Centre for Clinical Research Excellence in Infectious Diseases...

Unknown

HIV-HBV Co-Infection and Liver Disease

HIV Infections | HIV-HBV Co-Infection

Australia
The University of Queensland

Recruiting

A Trial to Treat Polyomavirus Infections (BKPyV) in Kidney and Simultaneous Kidney Pancreas Transplant Recipients (BEAT-BK)

Kidney Transplant Infection | Kidney Transplant Failure and Rejection | BK Viremia

Australia
The University of Queensland
The HOME Network; Australia and New Zealand Dialysis and Transplant Registry; New Zealand Peritoneal Dialysis Registry

Active, not recruiting

Targeted Education ApproaCH to Improve Peritoneal Dialysis Outcomes Trial (TEACH-PD)

Kidney Disease, Chronic | Peritoneal Dialysis Catheter Exit Site Infection | Peritoneal Dialysis Catheter-Associated Peritonitis | Peritoneal Dialysis Catheter Tunnel Infection

Australia, New Zealand
GlaxoSmithKline

Completed

A Randomized, Single Blind, Placebo Controlled Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Single Oral Doses and Repeat Escalating Oral Doses of GSK2251052 in Healthy Adult Subjects

Infections, Bacterial

Australia
GlaxoSmithKline

Terminated

A Study to Evaluate Safety, Tolerability and Pharmacokinetics of Ascending Intravenous Single Dose and Repeat Dose of GSK3342830

Infections, Bacterial

Australia
Azora Therapeutics Australia Pty Ltd

Completed

Study of Efficacy and Safety of Investigational Treatment in Patients With Hidradenitis Suppurativa

Hidradenitis Suppurativa

Australia
Murdoch Childrens Research Institute

Recruiting

BonE and Joint Infections - Simplifying Treatment in Children Trial (BEST)

Osteomyelitis | Septic Arthritis | Bone Infection | Bone and Joint Infection

New Zealand, Australia
Technovalia, Pty Ltd
Chulalongkorn University; Southern Star Research Pty Ltd.; BioNet-Asia

Active, not recruiting

Immunogenicity and Safety of ChulaCov19 BNA159 and ChulaCov19 BNA159.2 Vaccines as a Booster Dose in Adults

COVID-19, SARS CoV 2 Infection

Australia
GlaxoSmithKline

Completed

To Evaluate Safety, Tolerability, Pharmacokinetics, And Food Effect Of Single Doses Of GSK945237 In Healthy Subjects

Healthy Subjects | Infections, Bacterial

Australia
The Alfred
Merck Sharp & Dohme LLC

Completed

Human Papillomavirus in Young People Epidemiological Research 2 (HYPER2) (HYPER2)

Human Papillomavirus Infection | Human Papillomavirus

Australia
Clover Biopharmaceuticals AUS Pty Ltd

Recruiting

First-in-human Safety and Immunogenicity Study of SCB-1019 in Healthy Adults

Respiratory Syncytial Virus Infection

Australia
Wuhan BravoVax Co., Ltd.
Novotech (Australia) Pty Limited; Shanghai BravoBio Co., Ltd.

Not yet recruiting

Phase I Clinical Trial of a Candidate HPV Vaccine

Human Papillomavirus Infection

Australia
Pfizer

Completed

Safety, Pharmacokinetics (PK) and Tolerability Study of a Novel Drug for Treatment of Bacterial Infections

Gram-negative Bacterial Infection

Australia
GlaxoSmithKline

Terminated

A Four Part Study to Investigate Relative Bioavailability, Safety and Tolerability of up to 5 Oral Formulation of GSK2251052 in Order to Identify a Formulation for Further Evaluation in a Future Later Phase Study (Relative Bio)

Community-acquired Infection

Australia
Kirby Institute
Gilead Sciences; The University of New South Wales

Completed

Tenofovir in HIV/HBV Coinfection (TICO)

HIV Infection | Hepatitis B Coinfection

Australia, Thailand
Pfizer

Completed

An Evaluation Of Three Dose Levels Of 3-Antigen Staphylococcus Aureus Vaccine (SA3Ag) In Healthy Adults

Bacterial Infections | Staphylococcal Skin Infections | Staphylococcal Infections | Staphylococcal Vaccines | Immunotherapy, Active

Australia
Vaxine Pty Ltd
Central Adelaide Local Health Network Incorporated

Completed

Monovalent Recombinant COVID19 Vaccine (COVAX19)

Coronavirus Infection | COVID

Australia
The Alfred
Cellestis

Completed

Evaluation of Interferon-gamma Responses to HCMV Infection in HIV Positive Individuals

HIV Infection | CMV Infection

Australia
Bugworks Research Inc.
Avance Clinical Pty Ltd.

Terminated

The Safety, Tolerability, and Pharmacokinetics of Single and Multiple Ascending Doses of BWC0977 in Healthy Adult Volunteers

Bacterial Infections | Infectious Diseases

Australia
Bugworks Research Inc.
Avance Clinical Pty Ltd.

Completed

A First in Human Study of the Safety and Tolerability of Single and Multiple Doses of BWC0977 in Healthy Volunteers

Bacterial Infections | Infectious Diseases

Australia
Murdoch Childrens Research Institute
Royal Children's Hospital

Recruiting

Single Dose Intravenous Antibiotics for Complicated Urinary Tract Infections in Children (CHOICE UTI)

Infection | Pediatric Infectious Disease | Complicated Urinary Tract Infection

Australia, New Zealand
Vaxine Pty Ltd
Australian Respiratory and Sleep Medicine Institute

Not yet recruiting

A Randomised Controlled Phase 1 Study of Vaccine Therapy for Control or Cure of Chronic Hepatitis B Virus Infection (HBV003)

Chronic Hepatitis b

Australia
University of Adelaide

Completed

The Long-term Impact of Invasive Meningococcal Disease in Australian Adolescents and Young Adults (AMEND)

Meningococcal Infections | Neisseria Infection | Neisseria Meningitis Sepsis

Australia
NGM Biopharmaceuticals, Inc

Terminated

A Phase 1/2 Study to Assess the Safety, Tolerability and Pharmacokinetics of NGM621 in Healthy Subjects, and to Assess the Safety, PK and Efficacy in Subjects With Moderate to Severe ARDS Caused by COVID-19

SARS-CoV-2 Infection

Australia
Entasis Therapeutics

Completed

Evaluation of the Safety, Tolerability and Pharmacokinetics of Intravenous ETX2514 Administered in Healthy Subjects

Acinetobacter Baumannii Infection

Australia
Memo Therapeutics AG

Completed

To Assess the Safety and Tolerability of MTx-COVAB36 as a Therapeutic and Prophylactic Treatment Against COVID-19.

SARS-CoV-2 Infection

Australia
Syneos Health
F-star Therapeutics, Inc.

Completed

A Multiple Ascending Dose Phase I Study of SB 9200 in Treatment Naïve Adults With Chronic Hepatitis C Infection

Hepatitis C Infection

Australia, New Zealand

Clinical Trials on Healthcare-associated Infection in Australia

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