Clinical Trials on Healthy Participants With Moderate and High Cardiovascular Risk in United States
Total 104 results
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Edwards LifesciencesTerminatedModerate to High-risk Noncardiac SurgeryUnited States
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VA Office of Research and DevelopmentRecruitingOlder Men and Women With High Fall RiskUnited States
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University of ArizonaCompletedHigh Risk Pregnancy | Cesarean Wound Disruption With Postnatal ComplicationUnited States
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Fundación para la Investigación del Hospital Clínico...Hospital General Universitario Gregorio Marañon; Germans Trias i Pujol Hospital and other collaboratorsCompletedModerated-high Risk of Postoperative Pulmonary Complication | Abdominal Surgery Expected More Than Two HoursSpain, United States, Argentina, Sweden
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University of North Carolina, Chapel HillNational Heart, Lung, and Blood Institute (NHLBI)CompletedHypertension | Cardiovascular Disease RiskUnited States
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Rutgers, The State University of New JerseyMonell Chemical Senses CenterCompletedTreatment of Sweet Taste Receptors Without or With an Oral Rinse of Ibuprofen Solution in Healthy Participants | Treatment of Sweet Taste Receptors Without or With an Oral Rinse of Naproxen Solution in Healthy ParticipantsUnited States
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University of Colorado, DenverChildren's Hospital Colorado; Mead Johnson NutritionRecruitingHealthy Toddlers 12-36 Months of Age With Mild or Moderate MalnutritionUnited States
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UCB Biopharma SRLCompletedHealthy Study Participants | Participants With Mild AsthmaUnited States
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BayerCompletedModerate Risk of CVDPoland, United States, Italy, United Kingdom, Germany, Spain, Puerto Rico, Ireland
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Novartis PharmaceuticalsTerminatedMyelofibrosis With High Molecular Risk MutationsBelgium, Spain, United Kingdom, Hungary, Italy, Japan, Taiwan, Germany, Canada, Singapore, Austria, Australia, France, Israel, Sweden, Switzerland, Hong Kong, Greece, Turkey, Brazil, Russian Federation, Denmark, Portugal, Norway, Poland
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Massachusetts General HospitalRoche DiagnosticsRecruitingCardiovascular Risk Factor | Heart Failure With Reduced Ejection Fraction | Heart Failure With Normal Ejection Fraction | Heart Failure, Right Sided | Heart Failure With Mid Range Ejection FractionUnited States
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University of WashingtonGeneral ElectricCompletedArterial Occlusive Diseases | Hypertension | Pregnancy | Pregnancy, High Risk | Evidence of Liver TransplantationUnited States
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Duke UniversityBaxter Healthcare CorporationTerminatedHigh-risk, Non-cardiovascular SurgeriesUnited States
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iSpecimen IncRecruitingAutoimmune Diseases | Healthy | Cancer | Infectious Disease | Blood Disease | Gastrointestinal Complication | Dermatologic Disease | Women's Health: High-Risk PregnancyUnited States
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University of Massachusetts, WorcesterNot yet recruitingPregnancy, High Risk | Type 2 Diabetes Treated With InsulinUnited States
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Alnylam PharmaceuticalsRecruitingHypertension | High Cardiovascular RiskUnited States, Canada
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iSpecimen IncEnrolling by invitationAutoimmune Diseases | Healthy | Cancer | Infectious Disease | Blood Disease | Gastrointestinal Complication | Dermatologic Disease | Women's Health: High-Risk PregnancyUnited States
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Vanderbilt University Medical CenterRecruitingIdiopathic Pulmonary Arterial Hypertension | Heritable Pulmonary Arterial Hypertension | Unaffected Mutation Carriers: Healthy Participants With a Known BMPR2 Gene Mutation and Normal Pulmonary Pressure and RV Function on Echo | Healthy Individuals With no Cardiopulmonary DiseaseUnited States
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI); CelgeneRecruitingAcute Myeloid Leukemia | Chronic Myelomonocytic Leukemia | Myelodysplastic Syndrome With Excess Blasts | IDH2 Gene Mutation | Recurrent High Risk Myelodysplastic Syndrome | Refractory High Risk Myelodysplastic Syndrome | Blasts 20-30 Percent of Bone Marrow Nucleated CellsUnited States
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Yale UniversityCompletedHigh Risk Atherosclerotic Cardiovascular DiseaseUnited States
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University of North Carolina, Chapel HillNational Heart, Lung, and Blood Institute (NHLBI)Active, not recruitingWeight Loss | Cardiovascular Risk Factor | Diet, HealthyUnited States
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The Cleveland ClinicNational Heart, Lung, and Blood Institute (NHLBI)Active, not recruitingHeart Failure Risk Factors in Healthy IndividualsUnited States
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University of South WalesPublic Health Wales; Cwm Taf University Health BoardSuspendedCardiovascular Diseases | Health Behavior | Cardiovascular Risk FactorUnited Kingdom
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Boston Scientific CorporationRecruitingHeart Disease, Coronary | High-risk Percutaneous Coronary InterventionUnited States, Sweden
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Boston Children's HospitalCompletedCoronary Artery Disease Risk HighUnited States
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Stephan Grupp MD PhDUniversity of PennsylvaniaRecruitingPediatric and Young Adult Patientswith Hypodiploid or t(17;19) B-ALL | Infants With Very High Risk KMT2A B-ALL | Patients With Central Nervous System Relapse Who Did Not Receive Cranial Radiation or Bone Marrow TransplantationUnited States
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VA Office of Research and DevelopmentCompletedHeart Disease | Prevention | Health Risk AppraisalUnited States
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Memorial Sloan Kettering Cancer CenterWashington University School of Medicine; The Cleveland Clinic; Vanderbilt University...Active, not recruitingThoracic Surgery | Atrial Fibrillation in High Risk PatientsUnited States
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Tufts UniversityNational Institute on Minority Health and Health Disparities (NIMHD); Tougaloo... and other collaboratorsNot yet recruitingObesity | Diabetes | High Blood Pressure | Cardiometabolic Risk Factors | Nutrition SecurityUnited States
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University of CincinnatiCompletedStress | Depressive Symptoms | Health Behavior | Cardiovascular Risk Factor | Self EfficacyUnited States
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Wills EyeMid Atlantic RetinaCompletedProliferative Diabetic Retinopathy - High RiskUnited States
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University of California, Los AngelesNational Heart, Lung, and Blood Institute (NHLBI)WithdrawnHealthy | Heart Failure With Preserved Ejection FractionUnited States
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AstraZenecaCompletedHigh Risk Coronary Artery DiseaseUnited Kingdom
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Novartis PharmaceuticalsTerminatedPart 1 - Healthy Volunteers | Part 2 - Patients With HypertensionUnited States
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Scripps Translational Science InstituteQuest Diagnostics-Nichols InsituteCompletedPatients With Symptoms of Cardiac Arrhythmia at Risk for Atrial FibrillationUnited States
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University of OxfordKing's College London; University of Southampton; Barts & The London NHS Trust; University of Birmingham and other collaboratorsCompletedHypertension | Pregnancy, High Risk | Pre-Eclampsia | Hypertension, Pregnancy-InducedUnited Kingdom
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University of PennsylvaniaWithdrawnTypical Atrial Flutter | Risk Factors With Future Development of Atrial FlutterUnited States
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Biosensors Europe SARecruiting
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Abiomed Inc.RecruitingCardiogenic Shock | High Risk PCIUnited States
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Biosensors Europe SAActive, not recruitingAcute Coronary Syndrome | High Bleeding RiskUnited States, Canada, France, Italy, United Kingdom, Germany, Denmark
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Wake Forest University Health SciencesCompletedCardiovascular Diseases | Diabetes | Metabolic Syndrome | Liver Fat | Cardiovascular Risk Factor | Diet Habit | Dietary Modification | High Cholesterol | Triglycerides High | Low-density-lipoprotein-type | HDL Cholesterol, Low Serum | High Blood Sugar | Intra-abdominal Fat | High Density Lipoprotein DeficiencyUnited States
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University Hospital Plymouth NHS TrustCompleted
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Gustave Roussy, Cancer Campus, Grand ParisRecruitingHigh-Risk Neuroblastoma | Patient With Insufficient Response ChemoimmunotherapyFrance, Germany, Israel, Spain, United Kingdom, Belgium, Norway, Sweden, Finland, Australia, Czechia, Italy, Netherlands, Slovenia, Switzerland, Denmark, Greece, Lithuania, Slovakia
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)RecruitingUntreated Adult Acute Myeloid Leukemia | Myelodysplastic Syndrome With Excess Blasts | High Risk Myelodysplastic Syndrome | de Novo Myelodysplastic Syndrome | Acute Myeloid Leukemia With t(8;21); (q22; q22.1); RUNX1-RUNX1T1 | Acute Myeloid Leukemia With Inv(16)(p13.1q22); CBFB-MYH11 | Acute Myeloid... and other conditionsUnited States
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University of Maryland, BaltimoreAmerican Heart Association; University of Maryland, School of NursingActive, not recruitingCardiovascular Diseases | Healthcare Workers | Occupational Stress | Lifestyle Risk Reduction | Worksite Health PromotionUnited States
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University of UlsterDSM Nutritional Products, Inc.UnknownParticipants With the MTHFR 677TT GenotypeUnited Kingdom
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Atara BiotherapeuticsNational Cancer Institute (NCI); Memorial Sloan Kettering Cancer CenterCompletedEBV-induced Lymphomas | EBV-associated Malignancies | Transplant Patients With EBV Viremia at High Risk of Developing a Recurrent EBV LymphomaUnited States
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Bristol-Myers SquibbCompletedCoronary Artery Disease | Healthy ParticipantsUnited Kingdom
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University of RochesterActive, not recruitingObesity | Overweight | Healthy Lifestyle | Cardiovascular Risks | Implementation ResearchUnited States
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AstraZenecaCompletedPeripheral Arterial Disease (PAD) | Moderate Risk for Cardiovascular Disease (CVD)France, Netherlands, Switzerland, Greece, Belgium, Italy