Clinical Trials on Heart Valve Diseases

Total 378888 results

The Cleveland Clinic

Recruiting

Comparative Imaging Assessment of Valvular Heart Disease

Aortic Stenosis | Aortic Regurgitation | Valve Heart Disease

United States
The Cleveland Clinic

Terminated

Frequency of Reduced Leaflet Motion After Surgical Aortic Valve Replacement and Transcatheter Aortic Valve Replacement.

Aortic Valve Disorder

United States
Medstar Health Research Institute
Food and Drug Administration (FDA)

Completed

Transcatheter Aortic Valve Intervention-Live Transmission (VERITAS)

Aortic Valve Disorder

Italy, Switzerland, United States, Germany, Canada, United Kingdom
Foldax, Inc

Active, not recruiting

Early Feasibility Study for the Foldax TRIA Mitral Heart Valve Replacement (FOLDAX)

Mitral Valve Stenosis | Mitral Valve Disease | Mitral Valve Failure

United States
Edwards Lifesciences

Withdrawn

Early Feasibility Study of the CardiAQ™ TMVI System (Transfemoral and Transapical DS)

Cardiovascular Disease | Heart Disease | Heart Valve Disease | Mitral Insufficiency
Abbott Medical Devices

Recruiting

Clinical Trial to Evaluate the Safety and Effectiveness of Using the Tendyne Transcatheter Mitral Valve System for the Treatment of Symptomatic Mitral Regurgitation (SUMMIT)

Cardiovascular Diseases | Heart Valve Diseases | Mitral Regurgitation | Mitral Valve Insufficiency | Valve Disease, Heart | Mitral Insufficiency | Functional Mitral Regurgitation | Degenerative Mitral Valve Disease

United States, Canada
Assistance Publique Hopitaux De Marseille

Unknown

Impact of Diffuse Myocardial Fibrosis on the Ventricular Function in Regurgitant Left-Sided Valve Heart Diseases ( The DIFFUsE Study) (DIFFUsE)

Valve Heart Diseases

France
Johns Hopkins University
Catalyst Foundation

Recruiting

Optimization Post-TAVR to IMprove Activity Levels (OPTIMAL Study) (OPTIMAL)

Aortic Valve Disease | Aortic Valve Replacement

United States
Duk-Woo Park, MD
CardioVascular Research Foundation, Korea

Recruiting

Transpacific TAVR Registry (TP-TAVR)

Heart Valve Diseases | Aortic Valve Insufficiency

Korea, Republic of, United States, China
Abbott Medical Devices

Completed

Trifecta™ GT Post Market Clinical Follow-up

Aortic Valve Disease | Aortic Valve Disorder

United States, Canada, Portugal, United Kingdom, Estonia, Germany, Netherlands, Belgium, France, Italy, Poland, Spain
NeoChord

Recruiting

Multicenter Post-Market Observational Registry of the NeoChord Artificial Chordae Delivery System (AcChord)

Heart Valve Diseases | Mitral Regurgitation | Mitral Valve Insufficiency | Mitral Valve Prolapse | Mitral Valve Disease

Germany, Greece, Switzerland
Lawson Health Research Institute

Unknown

Patient Specific Mitral Valve Modeling for Surgical Planning and Training

Mitral Regurgitation | Mitral Valve Prolapse | Mitral Valve Disease
Xijing Hospital

Recruiting

Safety and Efficacy of Post-marketing Transcatheter Aortic Valves in "Real World" Chinese Patients

Aortic Valve Disease Mixed

China
Sheng Liu

Recruiting

Effect of RT3D-TEE-guided Mitral Valve Repair on Outcomes in Patients With Degenerative Mitral Valve Disease (TEEMR)

Degenerative Mitral Valve Disease

China
Tomsk National Research Medical Center of the Russian...

Active, not recruiting

Clinical and Fundamental Aspects of Prosthetics and Translocation of Mitral Valve Chordae

Degenerative Mitral Valve Disease

Russian Federation
Abbott Medical Devices

Completed

Trifecta™ Long Term Follow-Up (LTFU) Study

Aortic Valve Stenosis | Aortic Valve Insufficiency | Aortic Valve Incompetence | Aortic Valve Regurgitation

United States, Canada
Abbott Medical Devices

Completed

Aortic Valve Replacement With Trifecta(TM)

Aortic Valve Stenosis | Aortic Valve Insufficiency | Regurgitation, Aortic Valve | Aortic Valve Incompetence

United States
Abbott Medical Devices

Completed

An Observational, Prospective Evaluation of the Trifecta™ Valve

Aortic Valve Stenosis | Aortic Valve Insufficiency | Regurgitation, Aortic Valve | Aortic Valve Incompetence

Germany, Netherlands, France
Deutsches Herzzentrum Muenchen

Recruiting

The Prospecive OBSERVational Munich Interventional MITRAl-Valve Registry (OBSERV-MITRA)

Mitral Valve Stenosis | Mitral Valve Regurgitation | Tricuspid Valve Regurgitation

Germany
Karolinska University Hospital
Karolinska Institutet

Completed

Valve Leaflet Motion in Sutureless Bioprosthetic Aortic Valves

Aortic Valve Stenosis | Heart Valve Disease

Sweden
Institute for Clinical and Experimental Medicine
Faculty Hospital Kralovske Vinohrady; General University Hospital, Prague; VZW... and other collaborators

Completed

Novel Cardiac Imaging Prognostic Markers of Clinical Outcome in Patients With Chronic Aortic Regurgitation (MOLLI-GLS-Hx)

Aortic Valve Disorder

Czechia, Belgium
Ziekenhuis Oost-Limburg
Universitaire Ziekenhuizen KU Leuven

Recruiting

Freestyle-Perimount Calcification Comparison

Aortic Valve Disease | Valve Heart Disease

Belgium
LMU Klinikum
University Hospital, Essen; Heart Center Leipzig - University Hospital; Universitätsklinikum... and other collaborators

Recruiting

German Registry for Transcatheter Tricuspid Valve Interventions

Tricuspid Valve Insufficiency | Tricuspid Regurgitation | Heart Valve

Germany
Braile Biomedica Ind. Com. e Repr. Ltda.

Recruiting

Aortic or Mitral Valve Replacement With the Braile Biomédica® Bovine Pericardium Valvular Bioprosthesis

Aortic Valve Stenosis | Mitral Valve Insufficiency | Aortic Valve Insufficiency | Mitral Valve Stenosis | Mitral Valve Regurgitation | Aortic Valve Incompetence | Mitral Valve Incompetence | Aortic Valve Regurgitation

Brazil
Azienda Ospedaliero, Universitaria Pisana

Not yet recruiting

Patients With Severe TrIcuspid Regurgitation After triCvALve System Implantation (CRITICAL)

Severe Tricuspid Valve Regurgitation
Eric Y. Yang, MD PhD

Unknown

Primary Mitral Regurgitation Repair

Mitral Regurgitation | Mitral Valve Insufficiency | Mitral Valve Prolapse | Ventricular Remodeling | Mitral Valve Disease | Degenerative Mitral Valve Disease | Chronic Mitral Disease | Myxomatous Mitral Valve Degeneration

United States
Michele De Bonis

Completed

LOng-Term Fate of Moderate Aortic Regurgitation Left Untreated at the Time of Mitral Valve Surgery

Mitral Regurgitation | Aortic Regurgitation

Italy
Edwards Lifesciences

Completed

Safety and Early Feasibility Study of the Harpoon Medical Device (EFS) (EFS)

Mitral Valve Insufficiency | Mitral Valve Prolapse | Mitral Valve Regurgitation

Poland
Edwards Lifesciences

Completed

CE Mark Study for the Harpoon Medical Device in Poland

Mitral Valve Insufficiency | Mitral Valve Prolapse | Mitral Valve Regurgitation

Poland
Edwards Lifesciences

Terminated

A Clinical Study of the CardiAQ™ TMVI System (Transapical DS)

Cardiovascular Disease | Heart Disease | Heart Valve Disease | Mitral Insufficiency

Netherlands, United Kingdom, Denmark, France
Atlantic Health System

Recruiting

Comparison Study of Echocardiography and Cardiovascular Magnetic Resonance Imaging in the Assessment of Mitral and Aortic Regurgitation

Mitral Regurgitation | Aortic Regurgitation

United States
Ospedale San Raffaele

Unknown

Expiratory Flow Limitation and Mechanical Ventilation During Cardiopulmonary Bypass in Cardiac Surgery

Mitral Regurgitation | Aortic Regurgitation

Italy
Wake Forest University Health Sciences

Terminated

Using Beta Blockers to Treat Mitral Regurgitation (REGURG)

Mitral Regurgitation | Mitral Valve Insufficiency | Heart Disease | Heart Valve Disease

United States
P+F Products + Features USA Inc.
P+F Products + Features GmbH; Meditrial USA Inc.

Not yet recruiting

TRIcvalve biCAVal Valve System for Severe Tricuspid Regurgitation (TRICAV) (TRICAV)

Tricuspid Regurgitation | Tricuspid Valve Disease

United States
JC Medical, Inc.

Recruiting

J-Valve TF Early Feasibility Study (JVTF EFS)

Aortic Valve Disease | Aortic Regurgitation | Aortic Valve Insufficiency

United States
Academisch Medisch Centrum - Universiteit van Amsterdam...

Recruiting

Evaluation of Mitral Valve Insufficiency Under General Anesthesia (MITIGATE)

Mitral Regurgitation | Mitral Valve Insufficiency | Mitral Valve Disease

Netherlands
Michele De Bonis

Completed

Durability at 20 Years of Quadrangular Resection With Annular Plication for Mitral Regurgitation

Mitral Valve Disease

Italy
Biostable Science & Engineering

Completed

HAART Model 300 Annuloplasty Ring

Aortic Regurgitation

Belgium, Czech Republic, Germany
Abbott Medical Devices

Completed

Aortic Valve Replacement With Trifecta(TM)

Aortic Valve Stenosis | Aortic Valve Insufficiency | Regurgitation, Aortic Valve | Aortic Valve Incompetence

Canada
Genesis Medtech Corporation

Recruiting

Clinical Trial in China

Diseases of Aortic Valve | Aortic Regurgitation Disease

China
Innovative Cardiovascular Solutions
Yale Cardiovascular Research Group

Recruiting

Evaluation of Safety and Effectiveness of the EMBLOK EPS During TAVR

Aortic Valve Stenosis | Aortic Valve Disease | Aortic Valve Insufficiency | Aortic Valve Replacement

United States
Boston Scientific Corporation
Quintiles, Inc.

Withdrawn

REPRISE China - Clinical Evaluation in China

Stenoses, Aortic Valve

China
Abbott Medical Devices

Completed

Aortic or Mitral Valve Replacement With the Biocor and Biocor Supra

Aortic Valve Stenosis | Mitral Valve Insufficiency | Aortic Valve Insufficiency | Mitral Valve Stenosis | Mitral Valve Regurgitation | Aortic Valve Incompetence | Mitral Valve Incompetence | Aortic Valve Regurgitation

United States
Edwards Lifesciences

Completed

CE Mark Study for the Harpoon Medical Device (TRACER)

Mitral Valve Insufficiency | Mitral Valve Prolapse | Mitral Valve Regurgitation

Italy, United Kingdom
Edwards Lifesciences

Terminated

Safety and Performance Study of the Harpoon Mitral Valve Repair System

Mitral Valve Insufficiency | Mitral Valve Prolapse | Mitral Valve Regurgitation

Poland
Assistance Publique - Hôpitaux de Paris
European Association of Cardiovascular Imaging

Not yet recruiting

European Association of Cardiovascular Imaging Multiple and Mixed Valvular Disease Study (EACVI-MMVD)

Aortic Valve Stenosis | Aortic Valve Disease | Heart Valve Diseases | Mitral Valve Insufficiency | Aortic Valve Insufficiency | Mitral Valve Stenosis | Aortic Valve Stenosis With Insufficiency | Tricuspid Valve Insufficiency | Mitral Valve Disease | Tricuspid Valve Disease | Mitral Valve Insufficiency and... and other conditions

France
Edwards Lifesciences

Recruiting

TRISCEND JAPAN Study (TRISCEND JAPAN)

Cardiovascular Diseases | Heart Valve Diseases | Tricuspid Valve Regurgitation

Japan
Abbott Medical Devices

Recruiting

Real World Study of the Tendyne™ Mitral Valve System to Treat Mitral Regurgitation (RESOLVE-MR)

Mitral Valve Regurgitation

Norway, United Kingdom, Saudi Arabia, France, Germany, Italy, Austria, Belgium, Czechia, Israel, Netherlands, Spain, Switzerland
University of Alabama at Birmingham

Not yet recruiting

Understanding the Metabolic and Functional Derangement of Primary Mitral Regurgitation: a Feasibility Study Using Carbon 11(C-11) Acetate Cardiac Positron Emission Tomography Magnetic Resonance Imaging (PET-MRI)

Mitral Valve Regurgitation

United States
Epygon

Recruiting

First-In-Human Clinical Study for Treatment of Severe Mitral Valve INsufficiency With Epygon™ TRanscatheter Mitral VAlve System

Mitral Valve Regurgitation

Spain, Austria, Italy, Serbia

Clinical Trials on Heart Valve Diseases

Sponsors and Collaborators

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Drug Interventions

CROs by country

CROs in Rwanda

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Rare Diseases

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