Clinical Trials on Heart Valve Prolapse

Total 67246 results

Edwards Lifesciences

Terminated

V-Chordal Adjustable System for Chordal Replacement in Mitral Valve Insufficiency Due to Leaflet Prolapse

Mitral Leaflet Prolapse

Italy
Edwards Lifesciences

Completed

Safety and Early Feasibility Study of the Harpoon Medical Device (EFS) (EFS)

Mitral Valve Insufficiency | Mitral Valve Prolapse | Mitral Valve Regurgitation

Poland
Edwards Lifesciences

Completed

CE Mark Study for the Harpoon Medical Device in Poland

Mitral Valve Insufficiency | Mitral Valve Prolapse | Mitral Valve Regurgitation

Poland
Edwards Lifesciences

Completed

CE Mark Study for the Harpoon Medical Device (TRACER)

Mitral Valve Insufficiency | Mitral Valve Prolapse | Mitral Valve Regurgitation

Italy, United Kingdom
Edwards Lifesciences

Terminated

Safety and Performance Study of the Harpoon Mitral Valve Repair System

Mitral Valve Insufficiency | Mitral Valve Prolapse | Mitral Valve Regurgitation

Poland
Central Hospital, Nancy, France

Recruiting

STretch and Myocardial Characterization in Arrythmogenic Mitral Valve Prolapse-2 (STAMP-2)

Mitral Valve Prolapse

France
Massachusetts General Hospital
Leducq Foundation

Recruiting

Genetic Basis of Mitral Valve Prolapse (MVP)

Mitral Valve Prolapse

United States
Rambam Health Care Campus

Unknown

Exercise Capacity Evaluation in Patients With Non-rheumatic Mitral Valve Prolapse (MVP)

Mitral Valve Prolapse

Israel
NeoChord

Recruiting

Multicenter Post-Market Observational Registry of the NeoChord Artificial Chordae Delivery System (AcChord)

Heart Valve Diseases | Mitral Regurgitation | Mitral Valve Insufficiency | Mitral Valve Prolapse | Mitral Valve Disease

Germany, Greece, Switzerland
Lawson Health Research Institute

Unknown

Patient Specific Mitral Valve Modeling for Surgical Planning and Training

Mitral Regurgitation | Mitral Valve Prolapse | Mitral Valve Disease
Centro Cardiologico Monzino
Humanitas Hospital, Italy; Treviso Regional Hospital; IRCCS Ospedale San Raffaele

Recruiting

Multiparametric SCores for Prediction of Myocardial fIbrosis in Patients With MITral vAlve pRolapse (SCIMITAR)

Mitral Valve Prolapse

Italy
Unity Health Toronto
London Health Sciences Centre; Ottawa Heart Institute Research Corporation

Unknown

The Canadian Mitral Research Alliance (CAMRA) Trial CardioLink-2 (CAMRA)

Mitral Valve Prolapse

Canada
Sakarya University

Unknown

Using Pulse Counter Vigileo-Flotrac System in Transapical Off-pump Minimally Invasive Mitral Valve Repair

Mitral Valve Prolapse

Turkey
Abbott Medical Devices

Completed

St. Jude Medical Percutaneous Mitral Valve Repair Study (SJM PMVr)

Mitral Valve Prolapse

United Kingdom
French Cardiology Society
Institut National de la Santé Et de la Recherche Médicale, France; Centre National... and other collaborators

Completed

Mitral Valve Prolapse (MVP) - France Study (MVP-France)

Mitral Valve Prolapse

France
University of California, San Francisco

Not yet recruiting

Erector Spinae Plane Block for Minimally Invasive Mitral Valve Surgery

Mitral Regurgitation | Mitral Valve Insufficiency | Mitral Valve Prolapse

United States
National Heart Institute, Egypt

Unknown

Neochordae Technique in Mitral Valve Repair

Mitral Regurgitation | Mitral Valve Prolapse

Egypt
Universitaire Ziekenhuizen KU Leuven

Recruiting

Arrhythmic Mitral Valve Prolapse Detection Using Long-term Ambulatory Rhythm Monitoring (ALARM-PILOT)

Mitral Valve Prolapse | Ventricular Arrythmia

Belgium
NeoChord

Not yet recruiting

European FIH Study - NeoChord Transcatheter Mitral Repair System for Symptomatic Mitral Regurgitation

Heart Diseases | Cardiovascular Diseases | Heart Valve Diseases | Mitral Regurgitation | Mitral Valve Insufficiency | Mitral Valve Prolapse | Degenerative
Centre Hospitalier Universitaire, Amiens

Recruiting

Prognostic Impact of the Location of Mitral Valve Prolapse on the Long-term Results of Mitral Plasty (IPPVM)

Mitral Valve Prolapse | Mitral Plasty

France
CSD Labs GmbH

Completed

Automated Algorithm Based Analysis of Phonocardiograms of Newborns

Systolic Murmurs | Heart Murmurs | Mitral Valve Prolapse

Austria
CSD Labs GmbH

Completed

Automatic Differentiation of Innocent and Pathologic Murmurs in Pediatrics

Systolic Murmurs | Heart Murmurs | Mitral Valve Prolapse

Canada
University of Turin, Italy

Completed

Myocardial Protection in Minimally Invasive Mitral Valve Surgery

Mitral Valve Prolapse | Minimally Invasive Surgery | Myocardial Protection
Hospices Civils de Lyon

Recruiting

Impact of Preoperative Myocardial Fibrosis Related to Mitral Valve Prolapse on Postoperative Left Ventricular Remodeling (IMPARED)

Regurgitation, Mitral

France
Karolinska Institutet
Karolinska University Hospital

Recruiting

Arrhythmogenic Mitral Valve Disease in Patients Undergoing Mitral Valve Surgery (STELLA)

Mitral Regurgitation | Surgery | Mitral Valve Prolapse | Ventricular Arrythmia | Mitral Annular Disjunction

Sweden
Woolsthorpe Technologies, LLC

Completed

Cardiac Output Pulmonary Arterial Catheter Compared to FloWave™ 1000

Aortic Valve Disease | Mitral Regurgitation | Mitral Valve Prolapse | Congestive Heart Failure | Ischemic Cardiomyopathy | Tricuspid Regurgitation

United States
Central Hospital, Nancy, France

Completed

Myocardial Characterization of Arrhythmogenic Mitral Valve Prolapse (STAMP: STretch and Myocardial Characterization in Arrhythmogenic Mitral Valve Prolapse) (STAMP)

Mitral Valve Prolapse

France
Eric Y. Yang, MD PhD

Unknown

Primary Mitral Regurgitation Repair

Mitral Regurgitation | Mitral Valve Insufficiency | Mitral Valve Prolapse | Ventricular Remodeling | Mitral Valve Disease | Degenerative Mitral Valve Disease | Chronic Mitral Disease | Myxomatous Mitral Valve Degeneration

United States
Oslo University Hospital
University of Oslo; The Research Council of Norway

Recruiting

Effect and Safety of Flecainide and Metoprolol Versus Metoprolol Alone to Suppress Ventricular Arrhythmias in Arrhythmic Mitral Valve Prolapse (FLECAPRO)

Mitral Valve Prolapse | Ventricular Arrhythmias and Cardiac Arrest

Norway
Institut für Pharmakologie und Präventive Medizin

Completed

Operative Mitral Valve Reconstruction in Functional mv Insufficiency With Reduced Systolic Ventricle Function (REFORM-MR)

Mitral Valve Insufficiency | Mitral Valve Prolapse | Left Ventricular Systolic Dysfunction

Germany
Ospedale San Raffaele

Recruiting

Mitral Valve Prolapse, Arrhythmias and Mitral Valve Surgery (MVP-A&S)

Mitral Valve Prolapse | Cardiac Arrhythmia

Italy
Nantes University Hospital
University Hospital, Brest; Rennes University Hospital

Recruiting

Genetic and Phenotypic Characteristics of Mitral Valve Prolapse (MVP)

Mitral Valve Prolapse | Genetic Disease

France
Ospedale San Raffaele

Completed

Minimally Invasive or Conventional Edge-To-Edge Repair for Severe Mitral Regurgitation Due to Bileaflet Prolapse in Barlow's Disease: Does the Surgical Approach Have an Impact on the Long-term Results?

Barlow's Disease | Prolapse; Mitral
Centre Hospitalier Universitaire, Amiens

Recruiting

Early Mitral ValvE Repair Versus Watchful Waiting for Asymptomatic SEvere Degenerative Mitral Regurgitation (REVERSE-MR)

Degenerative Mitral Regurgitation (MR) Due to Leaflet Prolapse

France
Annetine Gelijns
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Percutaneous or Surgical Repair In Mitral Prolapse And Regurgitation for ≥60 Year-olds (PRIMARY) (PRIMARY)

Mitral Valve Regurgitation

United States, Germany, United Kingdom, Canada
Edwards Lifesciences
ICON plc

Terminated

Observational Registry on the HARPOON Device (REPLICATE)

Severe Degenerative Mitral Regurgitation Due to Mid-segment Posterior Leaflet Prolapse

Germany, Spain, Switzerland
Michele De Bonis

Completed

Long Term Results of Surgical and Percutaneous Double Orefices Mitral Repair in Patient With p2 Prolapse Causing Degenerative Mitral Regurgitation

Mitral Regurgitation | Degenerative Mitral Valve Disease

Italy
Lille Catholic University
University Hospital, Lille

Recruiting

Prognostic Impact of Imaging Parameters in Patients With Primary Mitral Insufficiency by Prolapse (COHORTE-IM) (COHORTE-IM)

Mitral Valve Insufficiency

France
Hospices Civils de Lyon

Withdrawn

Effectiveness and Safety of Mitral Valve Repair With the NeoChord DS1000 Artificial Chordae Delivery System Versus Conventional Surgery in Patients With Severe Primary Mitral Regurgitation Due to Isolated Leaflet Prolapse (MITRACHORD)

Cardiovascular Diseases

France
Closed Joint-Stock Company NeoCor
Research Institute for Complex Problems of Cardiovascular Diseases, Russia; CT Medical Limited Liability Company

Recruiting

Study on Efficacy, Safety and Durability of the UniLine Prosthesis in the Treatment of Aortic and Mitral Valve Disease

Diseases of Mitral and Aortic Valves | Valvular Heart Disease (Aortic and Mitral Valves) | Rheumatic Disorders of Mitral and Aortic Valves | Other Congenital Malformations of Aortic and Mitral Valves | Mitral Valve Insufficiency and Aortic Valve Insufficiency

Russian Federation
The Cleveland Clinic

Withdrawn

Does Dexamethasone Administration Improve Recovery In Patients Undergoing Minimally Invasive Sacrocolpopexy?

Quality of Life | Pelvic Organ Prolapse | Prolapses, Vaginal Vault

United States
Medical University of Vienna

Recruiting

Continuous Stitches Versus Simple Interrupted Stitches for Anterior Colporrhaphy

Pelvic Organ Prolapse | Cystocele | Vaginal Prolapse | Cystocele, Midline | Prolaps Bladder

Austria
Edwards Lifesciences

Completed

EDWARDS INTUITY Valve System FOUNDATION Study (FOUNDATION)

Aortic Stenosis | Aortic Valve Disease | Rapid Deployment Valves

Spain, United Kingdom, Austria, Netherlands, Italy, France, Germany, Denmark, Switzerland
Seung-Jung Park
CardioVascular Research Foundation, Korea

Withdrawn

Percutaneous Device Closure for Significant Paravalvular Leakage After Transcatheter or Surgical Valve Replacement (PVL closure)

Heart Valve Diseases | Valvular Insufficiency | Cardiac Valves

Korea, Republic of
Torben Pottgiesser

Recruiting

Risk Stratification Post TAVI Using TEG (RISTRATAVI)

Cardiovascular Diseases | Thrombosis | Aortic Valve Stenosis | Transcatheter Aortic Valve Replacement | Predictive Value of Tests | Thrombelastography | Platelet Function Tests

Germany
Clinical Hospital Centre Zagreb

Recruiting

Apixaban for the Prevention of Latent Biological Valve Thrombosis

Aortic Valve Replacement | Antithrombotic Therapy | Rapid Deployment Valves | Bioprosthetic Valve Thrombosis

Croatia
University of Alabama at Birmingham

Completed

Patient Experience and Bowel Preparation for Transvaginal Surgical Management of Vaginal Prolapse

Value of the Bowel Preparation and Diet Change Versus no Intervention | Preoperative Bowel Regimen

United States
Closed Joint-Stock Company NeoCor
Research Institute for Complex Problems of Cardiovascular Diseases, Russia; CT Medical Limited Liability Company

Recruiting

Post-market Clinical Monitoring of the Safety and Efficacy of the Aortic Valve Bioprothesis (TiAra)

Aortic Valve Disease | Artificial Heart Valves

Russian Federation
Assiut University

Completed

Phase Contrast in Valvular Heart Disease

Valvular Heart Disease (Aortic and Mitral Valves)

Egypt
Mansoura University

Recruiting

Overnight Bladder Drainage and Posterior Urethral Valve Sequelae

Posterior Urethral Valve

Egypt

Clinical Trials on Heart Valve Prolapse

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Kenya

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations