Clinical Trials on Helicobacter Infections in South Africa

Total 3308 results

Bugworks Research Inc.
Avance Clinical Pty Ltd.

Completed

A First in Human Study of the Safety and Tolerability of Single and Multiple Doses of BWC0977 in Healthy Volunteers

Bacterial Infections | Infectious Diseases

Australia
Boston University Charles River Campus
Massachusetts General Hospital; University of Witwatersrand, South Africa

Not yet recruiting

Identifying and Addressing Barriers to Retention in the Cervical Cancer Treatment Cascade Among Women With HIV in South Africa: Part 2

Cervical Cancer | Hiv

United States, South Africa
Sanford Health

Completed

Prevalence of Human Papillomavirus in Men Living in the Northern Plains

Human Papillomavirus Infection

United States
Centers for Disease Control and Prevention
Tuberculosis Trials Consortium

Recruiting

Short-course Regimens for the Treatment of Pulmonary Tuberculosis (CRUSH-TB)

Tuberculosis, Pulmonary | Tuberculosis Infection

Canada, United States, Haiti, South Africa, Uganda, Vietnam
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

Study of a Single Dose of Pretomanid Added to an Optimized Background Regimen in Children With Rifampicin-Resistant Tuberculosis

Tuberculosis | Rifampicin Resistant Tuberculosis

Brazil, India, South Africa, Tanzania, Thailand
Boston University Charles River Campus
National Institute of Mental Health (NIMH); University of Cape Town

Recruiting

Reducing Psychological Barriers to PrEP Persistence Among Pregnant and Postpartum Women in Cape Town, South Africa

Depression | Pregnancy Related | Medication Adherence | Posttraumatic Stress Disorder

United States, South Africa
National Institute of Allergy and Infectious Diseases...

Completed

Evaluating the Pharmacokinetics, Safety, and Tolerability of Doravirine (MK-1439) and Doravirine/Lamivudine/Tenofovir Disoproxil Fumarate (MK-1439A) in HIV-1-Infected Children and Adolescents

HIV Infections

United States, South Africa, Thailand
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Active, not recruiting

Evaluating the Pharmacokinetics, Safety, and Tolerability of Bedaquiline in Infants, Children, and Adolescents With Multidrug-Resistant Tuberculosis, Living With or Without HIV

HIV | Tuberculosis

Haiti, India, South Africa
Prof Gerhard Walzl
London School of Hygiene and Tropical Medicine; Makerere University; Leiden University... and other collaborators

Completed

Evaluation of Host Biomarker-based Point-of-care Tests for Targeted Screening for Active TB (ScreenTB)

Pulmonary Tuberculosis

United Kingdom, Uganda, Ethiopia, Gambia, Germany, Namibia, Netherlands, South Africa
Henry M. Jackson Foundation for the Advancement...
RedHill Biopharma Limited; FHI Clinical, Inc.; Joint Program Executive Office...

Recruiting

PROTECT-APT 1: Early Treatment and Post-Exposure Prophylaxis of COVID-19 (PROTECT-APT 1)

SARS-CoV-2

United States, Côte D'Ivoire, South Africa, Thailand
Techfields Inc

Terminated

Evaluate the Efficacy and Safety of TF0023 in Treatments for COVID-19 in Hospitalized Adults

COVID-19 Pneumonia

United States, South Africa
Gilead Sciences

Active, not recruiting

Pre-Exposure Prophylaxis Study of Lenacapavir and Emtricitabine/Tenofovir Alafenamide in Adolescent Girls and Young Women at Risk of HIV Infection (PURPOSE 1)

Pre-Exposure Prophylaxis of HIV Infection

South Africa, Uganda
Gilead Sciences

Completed

Efficacy and Safety of Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide in HIV-1 Infected Adolescents

HIV

United States, South Africa
GlaxoSmithKline

Completed

A Randomized, Single Blind, Placebo Controlled Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Single Oral Doses and Repeat Escalating Oral Doses of GSK2251052 in Healthy Adult Subjects

Infections, Bacterial

Australia
RTI International
Kheth'Impilo

Completed

Implementation Research for Vulnerable Women in South Africa

HIV | Substance Abuse

United States, South Africa
GlaxoSmithKline

Terminated

A Study to Evaluate Safety, Tolerability and Pharmacokinetics of Ascending Intravenous Single Dose and Repeat Dose of GSK3342830

Infections, Bacterial

Australia
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Study of Options for Second-Line Effective Combination Therapy (SELECT) (SELECT)

HIV-1 Infection

Peru, Kenya, Malawi, Brazil, South Africa, Zimbabwe, India, Thailand, Tanzania
Karex Industries Sdn. Bhd.
University of Witwatersrand, South Africa; Essential Access Health; Sigma3 Services...

Completed

Evaluation of 2 Synthetic Nitrile Male Condoms Compared to a Standard Latex Male Condom

Sexually Transmitted Diseases

United States, South Africa
University of Cape Town
World Health Organization; Medical Research Council, South Africa; Global Fund

Completed

Combination Antimalarials in Uncomplicated Malaria

Malaria

Mozambique, South Africa, Swaziland
University of North Carolina, Chapel Hill
National Institute on Drug Abuse (NIDA); National Institute on Alcohol Abuse... and other collaborators

Completed

Comparison of Three Hepatitis B Vaccination Regimens in HIV-Positive Youth

HIV Infection | Hepatitis B

Brazil, United States, South Africa
International Partnership for Microbicides, Inc.

Completed

To Assess Continued Safety of and Adherence to the Dapivirine (25 mg) Vaginal Ring-004 in Healthy, HIV-negative Women

HIV Prevention

South Africa, Uganda
University of Sydney

Unknown

Partially HLA-matched Third Party Antigen Specific T-cells for Infection Post-stem Cell or Solid Organ Transplantation (R3ACT)

CMV Infection | EBV | Adenovirus

Australia
GlaxoSmithKline

Completed

A Three-Part Study Of GSK580416 In Healthy Subjects

Infections, Bacterial | Respiratory Tract Infection

Australia
Maastricht University Medical Center

Completed

Incubation Time and Test of Cure of Chlamydia Trachomatis (Incure)

Chlamydia Trachomatis Infection

Netherlands
GlaxoSmithKline

Completed

To Evaluate Safety, Tolerability, Pharmacokinetics, And Food Effect Of Single Doses Of GSK945237 In Healthy Subjects

Healthy Subjects | Infections, Bacterial

Australia
GlaxoSmithKline

Completed

Single Dose Escalation First Time in Human PK Study

Infections, Bacterial

Australia
GlaxoSmithKline

Completed

A Repeat Dose Escalation Study to Investigate the Safety, Tolerability and Pharmacokinetics of GSK1322322 in Healthy Subjects

Infections, Bacterial

Australia
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Study of Effects of Tenofovir on Bone Health and Kidneys During Pregnancy and Breastfeeding

HIV Infections

Malawi, South Africa, Zimbabwe, Uganda
University of Cape Town
University of Michigan; Brigham and Women's Hospital; Fogarty International Center... and other collaborators

Completed

An Observational Study of Distress, Immune Function, and Pain in HIV.

Chronic Pain | HIV | Distress, Emotional | Central Sensitisation | Immune System and Related Disorders

South Africa
RTI International
University of North Carolina, Chapel Hill

Completed

WHC+ (Women's Health CoOp PLUS)

Sexually Transmitted Diseases | HIV | Substance Abuse | Violence | Victimization | Sexual Risk

United States, South Africa
PENTA Foundation
Institut National de la Santé Et de la Recherche Médicale, France; Program... and other collaborators

Active, not recruiting

A Randomised Trial of Dolutegravir (DTG)-Based Antiretroviral Therapy vs. Standard of Care (SOC) in Children With HIV Infection Starting First-line or Switching to Second-line ART

HIV Infection

United Kingdom, Spain, Portugal, South Africa, Thailand, Uganda, Germany, Zimbabwe
Tibotec Pharmaceuticals, Ireland
Tibotec Pharmaceutical Limited

Completed

A Safety Study to Evaluate the Antiviral Activity of Darunavir in Combination With Ritonavir in HIV 1 Infected Children

Human Immunodeficiency Virus 1

South Africa, Argentina, Brazil, India, Kenya
Kirby Institute

Completed

Bone and Body Comp: A Sub Study of the SECOND-LINE Study

HIV

Malaysia, South Africa, Argentina, India, Thailand
Microbicide Trials Network
National Institute of Allergy and Infectious Diseases (NIAID); Eunice Kennedy... and other collaborators

Completed

Observational Study of HIV Infected Women Previously Enrolled in Other Microbicide Trials

HIV Infections

Malawi, Zimbabwe, Uganda, South Africa, Zambia
ViiV Healthcare
GlaxoSmithKline

Completed

Study Of An Investigational Regimen Including FDA Approved HIV Drugs In HIV-Infected Pediatric Subjects

HIV Infections | Infection, Human Immunodeficiency Virus

United States, Portugal, Russian Federation, Mexico, Argentina, South Africa, Puerto Rico
Medical University of South Carolina
Oregon Health and Science University; Cystic Fibrosis Foundation

Completed

A Proof of Concept Study of Inhaled Nitric Oxide for Adults With Pulmonary Non-Tuberculous Mycobacterial Infection

Nontuberculous Mycobacterium Infection

United States
GlaxoSmithKline

Terminated

A Four Part Study to Investigate Relative Bioavailability, Safety and Tolerability of up to 5 Oral Formulation of GSK2251052 in Order to Identify a Formulation for Further Evaluation in a Future Later Phase Study (Relative Bio)

Community-acquired Infection

Australia
University of Adelaide

Completed

The Long-term Impact of Invasive Meningococcal Disease in Australian Adolescents and Young Adults (AMEND)

Meningococcal Infections | Neisseria Infection | Neisseria Meningitis Sepsis

Australia
Bayside Health
Merck Sharp & Dohme LLC

Unknown

Universal Prophylaxis Versus Pre-emptive Therapy With Posaconazole Post-Lung Transplant (UPPRITE)

Fungal Infection

Australia
Brigham and Women's Hospital
Harvard Medical School (HMS and HSDM); Massachusetts General Hospital; Columbia... and other collaborators

Active, not recruiting

Standing Tall (Yima Nkqo)

HIV

United States, South Africa
National Institute of Allergy and Infectious Diseases...
ViiV Healthcare

Suspended

Drug-Drug Interactions Between Rifapentine and Dolutegravir in HIV/LTBI Co-Infected Individuals

HIV Infection | LTBI

United States, Haiti, Botswana, Brazil, Thailand, Zimbabwe, Malawi, Peru, South Africa
Boehringer Ingelheim

Completed

Ambroxol Spray Sore Throat Study

Pain | Pharyngitis

South Africa
Maastricht University Medical Center
National Institute for Public Health and the Environment (RIVM); ZonMw: The... and other collaborators

Completed

Transmission of Genital and Extra-genital Chlamydia Trachomatis Infections in Women (FemCure)

Chlamydia Trachomatis Infection

Netherlands
Medical University of South Carolina
Memorial Sloan Kettering Cancer Center; Ralph H. Johnson VA Medical Center

Completed

Efficacy Of Copper To Reduce Acquisition Of Microbes and Healthcare-acquired Infections

Healthcare-acquired Infection

United States
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID); National Institute...

Completed

A Study of Dementia and Neurological Problems in HIV Infected Patients Who Are Participating in ACTG A5175

HIV Infections

South Africa, Brazil, Zimbabwe, India, Malawi
International Partnership for Microbicides, Inc.

Completed

A Safety Study of Dapivirine Vaginal Ring in Africa

HIV Infections

South Africa, Tanzania, Malawi, Kenya
Janssen-Cilag International NV

Completed

A Clinical Trial Comparing the Efficacy of Tenofovir Disoproxil Fumarate/Emtricitabine/Rilpivirine (TDF/FTC/RPV) Versus TDF/FTC/Efavirenz (TDF/FTC/EFV) in Patients With Undetectable Plasma HIV-1 RNA on Current First-line Treatment (SALIF)

Human Immunodeficiency Virus-type 1 Infection

South Africa, Kenya, Thailand, Uganda, Cameroon, Senegal
Medical University of South Carolina
The Skin Center Dermatology Group

Completed

Cold Atmospheric Plasma Device for Pediatric Molluscum and Verruca

Verruca Vulgaris | Molluscum Contagiosum Skin Infection

United States
Pfizer
ViiV Healthcare

Terminated

A Long Term Safety Study Of Lersivirine For The Treatment Of HIV-1 Infection In Subjects Who Have Completed Treatment With Lersivirine In Studies A5271015 And A5271022

HIV-1

South Africa, Australia, United Kingdom, Canada, Italy, Poland, Switzerland, Mexico, Brazil
The University of Queensland
Griffith University; The Prince Charles Hospital; Princess Alexandra Hospital... and other collaborators

Completed

Reducing Acute Severe Respiratory Events in Health Care Workers During the Covid-19 Pandemic With OM85 (COVIDRASP)

Covid19 | Respiratory Viral Infection

Australia

Clinical Trials on Helicobacter Infections in South Africa

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Poland

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

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