Clinical Trials on Hematologic Neoplasm With Germline GATA2 Mutation
Total 480 results
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NYU Langone HealthRecruitingNon-small Cell Lung Cancer With STK11/LKB1 MutationUnited States
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Li JunminWithdrawnMyelodysplastic Syndromes | P53 MutationChina
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI); CelgeneRecruitingAcute Myeloid Leukemia | Chronic Myelomonocytic Leukemia | Myelodysplastic Syndrome With Excess Blasts | IDH2 Gene Mutation | Recurrent High Risk Myelodysplastic Syndrome | Refractory High Risk Myelodysplastic Syndrome | Blasts 20-30 Percent of Bone Marrow Nucleated CellsUnited States
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI); Genentech, Inc.RecruitingAcute Myeloid Leukemia | Therapy-Related Acute Myeloid Leukemia | Hematologic and Lymphocytic Disorder | Acute Myeloid Leukemia in Remission | FLT3 Gene Mutation | Minimal Residual Disease PersistenceUnited States
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NYU Langone HealthWithdrawnAdvanced Non-small Cell Lung Cancer With KRAS G12C MutationUnited States
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Samsung Medical CenterActive, not recruitingNon-Small Cell Lung Cancer With EGFR T790M Mutation | With Brain and/or Leptomeningeal Metastasis | Failed Tyrosine Kinase InhibitorsKorea, Republic of
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NYU Langone HealthRecruitingAdvanced Non-small Cell Lung Cancer With KRAS G12C MutationUnited States
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Shanghai Chest HospitalRecruitingMetastatic Cancer | Adenocarcinoma of Lung | Non-Small Cell Lung Cancer With EGFR Mutation | Locally Advanced Solid TumorChina
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Novartis PharmaceuticalsActive, not recruitingLocally Advanced or Metastatic KRAS G12C-mutated NSCLC With a PD-L1 Expression <1% or a PD-L1 Expression ≥ 1% and an STK11 Co-mutationSpain, Italy, Austria, Netherlands, United Kingdom, Germany, Thailand, France, Belgium, China, Argentina, Greece, Turkey, Malaysia, Portugal, Hungary, Brazil, United States, India
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Kunming Medical UniversityRecruitingNon-Small Cell Lung Cancer With Mutation in Epidermal Growth Factor ReceptorChina
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Universitaire Ziekenhuizen KU LeuvenRecruitingNon-Small Cell Lung Cancer With Mutation in Epidermal Growth Factor ReceptorBelgium
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University of UtahActive, not recruitingNon-Small Cell Lung Cancer With Mutation in Epidermal Growth Factor Receptor (Disorder)United States
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Universität Duisburg-EssenTerminatedNon-small-cell Lung Cancer With Somatic EGFR Mutations
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Arog Pharmaceuticals, Inc.CompletedAcute Myeloid Leukemia With FLT3 Activating Mutations That Has Relapsed or Been Refractory After One or More Prior TherapiesUnited States
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Suzhou Suncadia Biopharmaceuticals Co., Ltd.Not yet recruitingPatients With Bone MetastasesChina
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Criterium, Inc.EMD Serono Research & Development Institute, Inc.TerminatedAdvanced Non-Small Cell Lung Cancer With MET MutationsUnited States
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Mayo ClinicNational Cancer Institute (NCI)TerminatedMyelodysplastic/Myeloproliferative Neoplasm With Ring Sideroblasts and Thrombocytosis, Not Otherwise Specified | Myelodysplastic/Myeloproliferative Neoplasm, Not Otherwise SpecifiedUnited States
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Ottawa Hospital Research InstituteCanadian Venous Thromboembolism Clinical Trials and Outcomes Research (CanVECTOR)... and other collaboratorsActive, not recruitingPrimary Myelofibrosis | Venous Thromboembolism (VTE) | Polycythemia Vera (PV) | Essential Thrombocythemia (ET) | JAK2 Mutation | Myeloproliferative Neoplasm (MPN)Canada
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Jiangsu HengRui Medicine Co., Ltd.Not yet recruitingNon-Small Cell Lung Cancer With HER2- MutationsChina
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SCRI Development Innovations, LLCBristol-Myers SquibbWithdrawnMyelodysplastic Syndromes | Leukemia, Myeloid, Acute | Myelodysplastic Syndrome Acute Myeloid LeukemiaUnited States
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Sidney Kimmel Cancer Center at Thomas Jefferson...Active, not recruitingAcute Myeloid Leukemia | Hodgkin Lymphoma | Chronic Myelomonocytic Leukemia | Myelodysplastic Syndrome | Plasma Cell Myeloma | Aplastic Anemia | Malignant Neoplasm | Myeloproliferative Neoplasm | Indolent Non-Hodgkin Lymphoma | Acute Myeloid Leukemia in Remission | Refractory Anemia | Refractory Anemia With... and other conditionsUnited States
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Guangzhou Institute of Respiratory DiseaseShanghai Junshi Bioscience Co., Ltd.UnknownIIIb/IV NSCLC With T790M Positive Mutations Failed to Osimertinib TherapyChina
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AIO-Studien-gGmbHBoehringer IngelheimTerminatedNon-small-cell Lung Cancer With Somatic EGFR MutationsGermany
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Instituto Nacional de Cancerologia de MexicoRecruitingNon-Small Cell Lung Cancer With EGFR MutationMexico
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Alexandru EniuIuliu Hatieganu University of Medicine and PharmacyCompletedTo Determine the Prevalence, Penetrance of BRCA1 and BRCA2 Mutations in Romanian Womens With Breast or Ovarian CancerRomania
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PfizerCompletedNon-small Cell Lung Cancer With EGFR-Activating MutationsItaly, Poland, China, Hong Kong, Spain, Korea, Republic of, Japan
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Central Hospital, Nancy, FranceInserm U954 - N-GERE (Nutrition, Genetics and Exposition to Environmental...UnknownHigh-risk Myelodysplastic Syndromes With Excess BlastsFrance
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zr Pharma & GmbHFoundation MedicineCompletedOvarian Cancer | Fallopian Tube Cancer | Peritoneal Cancer | Advanced Solid Tumor With Evidence of Germline or Somatic BRCAUnited States, Israel, Spain, Canada, United Kingdom
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Shanghai Zhongshan HospitalUnknownMyeloproliferative Neoplasm | Gastroesophageal Varices | JAK2 Mutation
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Wake Forest University Health SciencesNational Cancer Institute (NCI)TerminatedLymphoma | Multiple Myeloma | Solid Tumor | Malignant Neoplasm | Mutation AbnormalityUnited States
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Daiichi SankyoDaiichi Sankyo Co., Ltd.Active, not recruitingNon-Small Cell Lung Cancer Metastatic | Non-Small Cell Lung Cancer With Mutation in Epidermal Growth Factor ReceptorUnited States, Spain, Korea, Republic of, France, United Kingdom, Taiwan, Australia, Japan, China, Netherlands, Italy, Germany, Austria, Belgium, Bulgaria, Singapore
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AstraZenecaNo longer availablePSR Ovarian Cancer With a BRCA MutationJapan
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Astellas Pharma IncTerminatedEGFR-TKI-naïve Patients With NSCLC Harboring EGFR Activating MutationsJapan
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Radiotherapy Oncology Centre "Santa Maria" HospitalPaola Anselmo,MD; Michelina Casale,PhD; Fabio Trippa,MDRecruitingNSCLC | Non Small Cell Lung Cancer | EGF-R Positive Non-Small Cell Lung Cancer | Non Small Cell Lung Cancer Metastatic | NSCLC Stage IV | Oligometastatic Disease | Non-Small Cell Squamous Lung Cancer | Non-Small Cell Lung Cancer With Mutation in Epidermal Growth Factor Receptor | Non-Small Cell Adenocarcinoma and other conditionsItaly
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RenJi HospitalPeking University First Hospital; Shanghai Zhongshan Hospital; First Affiliated... and other collaboratorsRecruitingKidney Cancer | Renal Cell Carcinoma | ALK Gene Mutation | MET Gene Mutation | HLRCC | Renal Tumor Histology | Cutaneous Leiomyoma | BAP1 Tumor Predisposition Syndrome | VHL Syndrome | Birt-Hogg-Dube Syndrome | Familial Renal Cancer | FLCN Gene Mutation | FH Gene Mutation | Cutaneous Leiomyomata With Uterine LeiomyomataChina
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Medolution Ltd.RecruitingBrain Metastases | Non-Small Cell Lung Cancer With EGFR MutationChina
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Blueprint Medicines CorporationActive, not recruitingMast Cell Leukemia | Aggressive Systemic Mastocytosis | Advanced Systemic Mastocytosis | Systemic Mastocytosis With an Associated Hematologic NeoplasmUnited States, Canada, United Kingdom, France, Netherlands, Italy, Spain, Austria, Denmark, Germany, Norway, Poland
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Centre Hospitalier Universitaire de BesanconRecruiting
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University Hospital, BrestRecruitingMyelodysplastic Syndromes | Myelodysplastic Syndrome With Isolated Del(5Q) | Myelodysplastic Syndrome With Del(5Q)France
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Dana-Farber Cancer InstituteAbbVie; Pharmacyclics LLC.Active, not recruitingWaldenstrom Macroglobulinemia | MYD88 Gene MutationUnited States
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Ruijin HospitalRecruitingMyelodysplastic Syndromes | Myelodysplastic Syndrome With Excess Blasts-2 | Myelodysplastic Syndrome With Excess Blasts-1China
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Children's Hospital Medical Center, CincinnatiRecruitingNeurofibromatosis 1 | Noonan Syndrome | Legius Syndrome | Cardiofaciocutaneous Syndrome | Costello Syndrome | SYNGAP1-Related Intellectual Disability | DLG4 | RAS Mutation | Noonan Syndrome With Multiple Lentigines | Noonan Neurofibromatosis Syndrome | Smith-Kingsmore Syndrome | MTOR Gene Mutation | GATOR-1 Gene... and other conditionsUnited States
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Onconova Therapeutics, Inc.TerminatedMyelodysplastic Syndrome | MDS | Refractory Anemia With Excess Blasts | RAEBUnited States, Spain, Canada, France, Australia, Switzerland, Israel, Japan, Belgium, India, Ireland, United Kingdom, Croatia, Czechia, Poland, Estonia, Germany, Italy, Austria, Hungary, Russian Federation, Sweden
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David IberriTerminatedAcute Myeloid Leukemia (AML) With Multilineage Dysplasia Following Myelodysplastic Syndrome, in Adults | AML (Adult) With 11q23 (MLL) Abnormalities | AML (Adult) With Del (5q) | AML (Adult) With Inv (16) (p13; q22) | AML (Adult) With t (16;16) (p13; q22) | AML (Adult) With t (8; 21) (q22; q22) and other conditionsUnited States
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Case Comprehensive Cancer CenterCompletedMyelodysplastic Syndromes | Thrombocytopenia | Chronic Myelomonocytic Leukemia | de Novo Myelodysplastic Syndromes | Refractory Anemia | Refractory Anemia With Excess Blasts | Refractory Cytopenia With Multilineage Dysplasia | Refractory Anemia With Ringed SideroblastsUnited States
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National Cancer Institute (NCI)CompletedChronic Myelomonocytic Leukemia | Previously Treated Myelodysplastic Syndromes | de Novo Myelodysplastic Syndromes | Refractory Anemia | Refractory Anemia With Excess Blasts | Refractory Cytopenia With Multilineage Dysplasia | Refractory Anemia With Excess Blasts in Transformation | Refractory Anemia...United States
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Boston Children's HospitalCompletedAML | ALL | Biphenotypic Leukemia | Refractory Anemia | Refractory Cytopenia With Multilineage Dysplasia | Refractory Anemia With Ringed Sideroblasts | Undifferentiated Leukemia | Ref. Cytopenia w Multilineage Dysplasia & Ringed Sideroblasts | Refractory Anemia With Excess Blasts-1 (5-10% Blasts) | Refractory... and other conditionsUnited States
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National Cancer Institute (NCI)RecruitingChronic Myelomonocytic Leukemia | Myelodysplastic Syndrome | Myelodysplastic Syndrome With Excess Blasts | Myeloproliferative NeoplasmUnited States, Canada
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Shanghai JMT-Bio Inc.Not yet recruitingImaging Examination Shows at Least One Site With Bone Metastases From Soild Tumors
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Queen Mary University of LondonAstraZeneca; Cancer Research UKUnknownSquamous Cell Lung Cancer | Triple-Negative Breast Cancer | Non-squamous Cell Lung Cancer With KRAS Mutations | Non-squamous Cell Lung Cancer With Wild-type KRASUnited Kingdom