Clinical Trials on Hemoglobinopathies

Total 1326 results

Società Italiana Talassemie ed Emoglobinopatie

Recruiting

STUDY INCIDENCE AND CHARACTERISTICS OF MALIGNANT NEOPLASIES IN PATIENTS WITH HEMOGLOBINOPATHY FOLLOWED IN ITALY (Tum001)

Malignacy, Hemoglobinopathie

Italy
Società Italiana Talassemie ed Emoglobinopatie

Recruiting

Observational Study for Patients With Hemoglobinopathies and Rare Inherited Anemia and Covid 19

Haemoglobinopathies

Italy
medac GmbH
Syneos Health; Celerion; Venn Life Sciences

Completed

Treosulfan-based Versus Busulfan-based Conditioning in Paediatric Patients With Non-malignant Diseases

Bone Marrow Failure Syndromes | Inborn Errors of Metabolism | Primary Immunodeficiencies | Haemoglobinopathies

Poland, Czechia, Germany, Italy
Sohag University

Not yet recruiting

Transcranial Doppler in Children With Hemoglobinopathies

Hemoglobinopathies
St. Jude Children's Research Hospital

Recruiting

Discarded Bone Marrow for Hematology Research

Hemoglobinopathies

United States
University Hospital, Montpellier

Not yet recruiting

Total Splenectomy vs Partial Splenectomy in Non-malignant Hemoglobinopathies : Study Comparing the Effectiveness

Splenectomy; Status

France
University Hospital, Basel, Switzerland

Completed

Screening for Hemoglobinopathies in Pregnant Women

Hemoglobinopathies

Switzerland
HaEmek Medical Center, Israel

Completed

Characteristics of Hgb C Carriers in Northern Israel and Clinical Features Among Hgb Homozygous

Hgb C Hemoglobinopathy

Israel
Children's Hospital of Philadelphia

Active, not recruiting

Reduced Intensity Conditioning (RIC) Regimen for Patients With Non-malignant Disorders (RIC)

Hemoglobinopathies | Immunodeficiencies | Non Malignant Diseases

United States
Azienda Ospedaliera V. Cervello

Unknown

Interferon and Ribavirin Treatment in Patients With Hemoglobinopathies (IFNRIBAHE)

Hemoglobinopathies

Italy
Masonic Cancer Center, University of Minnesota

Recruiting

Second or Greater Allogeneic Hematopoietic Stem Cell Transplant Using Reduced Intensity Conditioning (RIC)

Hemoglobinopathies | Immunodeficiencies | Hematologic Disorders

United States
Bristol-Myers Squibb

Recruiting

A Study to Determine the Efficacy and Safety of Luspatercept in Adult and Adolescent Participants With Alpha (α)-Thalassemia

Anemia

Thailand, China, Canada, Turkey, Greece, Taiwan, Italy, Hong Kong
Emory University
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

STRIDE Biorepository

Anemia, Sickle Cell

United States
Celgene
Acceleron Pharma, Inc., a wholly-owned subsidiary of Merck & Co., Inc., Rahway...

Completed

A Study to Determine the Efficacy and Safety of Luspatercept in Adults With Non Transfusion Dependent Beta (β)-Thalassemia (BEYOND)

Thalassemia

United States, Greece, Italy, Lebanon, Thailand, United Kingdom
UCSF Benioff Children's Hospital Oakland
Children's Hospital of Philadelphia; National Heart, Lung, and Blood Institute... and other collaborators

Completed

Zinc & Bone Health in Thalassemia: The Think Zinc Study (ThinkZn)

Thalassemia

United States
Ionis Pharmaceuticals, Inc.

Completed

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ISIS 702843 Administered Subcutaneously to Healthy Volunteers

Thalassemia

Australia
HealthCore-NERI
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Assessment of Pain in People With Thalassemia Who Are Treated With Regular Blood Transfusions

Thalassemia

United States, Canada
Reem Ali Shaker

Recruiting

Pharmacotherapy Prescribing Pattern and the Adherence Level to Iron Chelation Therapy in Thalassemia

Thalassemia

Iraq
Menoufia University

Completed

Assessment of Nutritional Status and Role of Insulin-like Growth Factor-1 in Children

Thalassemia

Egypt
Baylor College of Medicine

Terminated

Allogeneic Stem Cell Transplantation, Severe Homzygous 0/+Thalassemia or Sever Variants of Beta 0/+ Thalassemia, THALLO (THALLO)

Thalassemia

United States
The First Affiliated Hospital, Guangzhou University...

Unknown

Colla Corii Asini Treating Anemia in Pregnant Women With Thalassemia(Presenting the Syndrome of Blood Deficiency)

Thalassemia

China
Xiao-Lin Yin

Unknown

The Effective and Safety of Thalidomide in TI

Thalassemia

China
Xiao-Lin Yin

Unknown

The Effective and Safety of Thalidomide in NTDT

Thalassemia

China
Yanfang Li

Unknown

Therapeutic Effect of Colla Corii Asini on Improving Anemia and Hemoglobin Composition in Pregnant Women With Thalassemia

Thalassemia

China
HealthCore-NERI
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Assessment of Pain in People With Thalassemia (Pain)

Thalassemia

United States, Canada
Children's Hospital Medical Center, Cincinnati

Withdrawn

Dipyridamole/Magnesium To Improve Sickle Cell Hydration

Anemia, Sickle Cell

United States
Washington University School of Medicine

Terminated

Skin and Blood Research Samples From Healthy Volunteers and Patients With Hematologic Diseases

Anemia, Sickle Cell

United States
Novartis Pharmaceuticals

Completed

Evaluation of Efficacy of Zoledronic Acid in Patients With Haemoglobin Syndromes (Thalassemia and Sicle Cell Anaemia) and Risk of Skeletal Events

Thalassemia

Greece
HealthCore-NERI
National Heart, Lung, and Blood Institute (NHLBI); Thalassemia Clinical Research...

Completed

Evaluating People With Thalassemia: The Thalassemia Longitudinal Cohort (TLC) Study

Thalassemia

United States, Canada, United Kingdom
Fakultas Kedokteran Universitas Indonesia

Not yet recruiting

Thalassemia Knowledge in Young People of Indonesia

Thalassemia

Indonesia
Agios Pharmaceuticals, Inc.

Active, not recruiting

A Study to Determine the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of AG-348 in Adult Participants With Non-transfusion-dependent Thalassemia

Thalassemia

United States, Canada, United Kingdom
Hillhurst Biopharmaceuticals, Inc.
National Heart, Lung, and Blood Institute (NHLBI)

Completed

A Study to Assess the Safety and Pharmacokinetics of HBI-002, an Oral Carbon Monoxide Therapeutic, in Healthy Volunteers

Anemia, Sickle Cell

United States
Hangzhou Zede Pharma-Tech Co., Ltd.

Completed

Short-term Clinical Study of CN128 in Thalassemia Patients

Thalassemia

China
Blood Diseases Clinic
University of Peshawar

Completed

Efficacy and Safety of Low Dose Thalidomide in Transfusion Dependent Thalassemia (Thal-Thalido)

Thalassemia

Pakistan
Hangzhou Zede Pharma-Tech Co., Ltd.

Completed

Clinical Study of CN128 in Thalassemia Patients

Thalassemia

China
Global Blood Therapeutics

Completed

A Study of the Absorption, Metabolism, and Excretion of GBT440 in Healthy Male Subjects

Anemia, Sickle Cell

United States
Guang'anmen Hospital of China Academy of Chinese...

Completed

Study of Effects of YisuiShengxueGranules on Thalassemia (thalessemia)

Thalassemia
Mersin University

Completed

The Effect of Acupressure on Pain in Children With Thalassemia (acupressure)

Pain

Turkey
The First Affiliated Hospital, Guangzhou University...
National Natural Science Foundation of China

Unknown

Study on the Mechanism of Colla Corri Asini in the Treatment of Thalassemia Patients With Pregnancy Anemia

Pregnancy | Thalassemia

China
Montefiore Medical Center

Completed

Intranasal Fentanyl for Initial Treatment of a Vaso-occlusive Crisis

Pain | Anemia, Sickle Cell

United States
Children's Hospital Medical Center, Cincinnati
Children's Hospital of Philadelphia; Emory University; Nemours Children's Health...

Not yet recruiting

A Socio-ecological Approach for Improving Self-management in Adolescents With SCD (SC-Thrive)

Anemia, Sickle Cell
Hillhurst Biopharmaceuticals, Inc.
National Heart, Lung, and Blood Institute (NHLBI)

Not yet recruiting

A Safety, Efficacy, and Pharmacokinetic (PK) Study of HBI-002, an Oral Carbon Monoxide (CO) Therapeutic, in Subjects With Sickle Cell Disease (SCD)

Anemia, Sickle Cell

United States
Indiana University
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Telemedicine for Children With Sickle Cell Disease

Anemia, Sickle Cell

United States
Washington University School of Medicine
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Specifying Interventions From the Sickle Cell Disease Implementation Consortium (SCDIC)

Anemia, Sickle Cell

United States
Children's Hospital Medical Center, Cincinnati

Recruiting

Therapeutic Response Evaluation and Adherence Trial (TREAT) (TREAT)

Anemia, Sickle Cell

United States
Società Italiana Talassemie ed Emoglobinopatie
Associazione Italiana de Ematologia e Oncologia Pediatrica; Società Italiana...

Completed

Transfusion Treatment in Patients With SCD

Anemia, Sickle Cell

Italy
Prolong Pharmaceuticals

Completed

Study of SANGUINATE™ In the Treatment of Sickle Cell Disease Patients With Vaso-Occlusive Crisis

Anemia, Sickle Cell

United States
St. Jude Children's Research Hospital

Completed

Use of Hydroxyurea and Magnesium Pidolate for Treatment of Sickle Cell Disease

Anemia, Sickle Cell

United States
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

Establishing a Database of People With Sickle Cell Disease (Comprehensive Sickle Cell Centers Collaborative Data Project [C-Data]) (C-Data)

Anemia, Sickle Cell

United States
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

Establishing a Repository of Blood and DNA Samples From People With Sickle Cell Disease (Comprehensive Sickle Cell Centers Collaborative Genotype-Phenotype Database and Sample Repository) (Gen/Phen)

Anemia, Sickle Cell

United States

Clinical Trials on Hemoglobinopathies

Sponsors and Collaborators

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Drug Interventions

CROs by country

CROs in Kenya

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Rare Diseases

Drug Interventions

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