Clinical Trials on Hemostatic Disorders in United Kingdom

Total 60342 results

Novo Nordisk A/S

Completed

Activated Recombinant Human Factor VII in Pelvic-acetabular Fracture Reconstruction

Trauma | Acquired Bleeding Disorder

United Kingdom
Novo Nordisk A/S

Completed

Safety and Pharmacokinetics of Recombinant Factor XIII in Healthy Volunteers

Healthy | Congenital Bleeding Disorder | Congenital FXIII Deficiency

United Kingdom
Novo Nordisk A/S

Completed

Safety and Pharmacokinetics of Recombinant Factor XIII Administration in Healthy Volunteers

Healthy | Congenital Bleeding Disorder | Congenital FXIII Deficiency

United Kingdom
Novo Nordisk A/S

Completed

Comparison of a Blood Clotting Drug (Recombinant Factor XIII) Produced by Two Different Manufacturers in Healthy Male Subjects

Healthy | Congenital Bleeding Disorder | Congenital FXIII Deficiency

United Kingdom
Imperial College London

Completed

RAS and Coagulopathy in COVID19

COVID

United Kingdom
Novo Nordisk A/S

Completed

Safety and Efficacy of Monthly Replacement Therapy With Recombinant Factor XIII (rFXIII) in Paediatric Subjects With Congenital Factor XIII A-subunit Deficiency (mentor™5)

Congenital Bleeding Disorder | Congenital FXIII Deficiency

United Kingdom, Israel, United States
Royal Brompton & Harefield NHS Foundation Trust

Terminated

Sequestration of Platelets Prior to Bypass Reduces Bleeding After Cardiac Surgery

Blood Coagulation Disorders | Blood Platelet Disorders | Cardiopulmonary Bypass | Cardiac Surgical Procedures

United Kingdom
Novo Nordisk A/S

Completed

Post-marketing Safety Surveillance of NovoSeven® in Patients With Haemophilia and Inhibitors by Means of the UK Haemophilia Database

Congenital Bleeding Disorder | Haemophilia A | Haemophilia B

United Kingdom
University of Leeds
Merck Sharp & Dohme LLC; Celgene; Amgen

Unknown

Use of Thalidomide, Lenalidomide, Carfilzomib, Bortezomib and Vorinostat in the Initial Treatment of Newly Diagnosed Multiple Myeloma Patients (Myeloma XI)

Multiple Myeloma

United Kingdom
Novo Nordisk A/S

Completed

Investigation of the Pharmacokinetics of NNC172-2021, at Two Different Dose Levels, in Healthy Japanese Subjects

Healthy | Congenital Bleeding Disorder | Haemophilia A | Haemophilia B

United Kingdom
Novo Nordisk A/S

Completed

A Single Dose Trial Investigating Safety and Local Tolerability of Ascending Doses of Long Acting Activated Recombinant Human Factor VII in Healthy Male Volunteers

Healthy | Congenital Bleeding Disorder | Haemophilia A | Haemophilia B

United Kingdom
Novo Nordisk A/S

Completed

Investigating Safety and Pharmacokinetics of NNC 0128-0000-2011 Compared to NNC 0128-0000-2021 in Healthy Male Subjects

Congenital Bleeding Disorder | Haemophilia A | Haemophilia B

United Kingdom
King's College Hospital NHS Trust

Completed

A Dose Escalation Study of the Combination of Lenalidomide (Revlimid®), Dexamethasone and Cyclophosphamide in Patients Refractory or Relapsing From Stable Disease With Multiple Myeloma (CRD)

Multiple Myeloma

United Kingdom
NHS Lothian
University of Edinburgh

Completed

Clotting Parameters After Medical Abortion (C-PLAN)

Venous Thromboembolism | Abortion, Second Trimester | Venous Thromboses | Abortion Early | Venous Thromboembolic Disease | Clotting Disorder | Abortion, Complete | Termination of Pregnancy Complicated by Embolism

United Kingdom
University College, London

Completed

Bortezomib Consolidation Trial (BCT)

Multiple Myeloma

United Kingdom
Cwm Taf University Health Board (NHS)
Cardiff Metropolitan University

Recruiting

Extracellular Vesicles and Dysregulated Coagulation in the Prediction of Stroke (PREDICT-EV)

Transient Ischemic Attack | Coagulation Disorder | Stroke, Ischemic

United Kingdom
Royal Marsden NHS Foundation Trust

Completed

Assessing Free Immunoglobulin Light Chains in Patients With Myeloma

Multiple Myeloma

United Kingdom
Novo Nordisk A/S

Completed

A Single Dose Trial of NNC 0155-0000-0004 in Patients With Haemophilia A

Congenital Bleeding Disorder | Haemophilia A

United Kingdom, Malaysia
University of Leeds
Celgene Corporation; Oncolytics Biotech; Myeloma UK

Unknown

Viral Immunotherapy in Relapsed/Refractory Multiple Myeloma (MUKeleven)

Multiple Myeloma

United Kingdom
Imperial College London
British Heart Foundation

Active, not recruiting

Studies of White Blood Cells Derived From HHT Patients

Telangiectasia, Hereditary Hemorrhagic

United Kingdom
Institute of Cancer Research, United Kingdom
Royal Marsden NHS Foundation Trust; Cancer Research UK; National Institute for...

Completed

Imageguided Theranostics in Multiple Myeloma (iTIMM)

Cancer | Myeloma

United Kingdom
University of Leeds
Merck Sharp & Dohme LLC; Myeloma UK

Completed

Vorinostat, Bortezomib and Dexamethasone in Multiple Myeloma (MUKFour) (MUKfour)

Multiple Myeloma

United Kingdom
Institute of Cancer Research, United Kingdom
Royal Marsden NHS Foundation Trust

Recruiting

CORONADO (Circulating tumOur pROtein quaNtification cApillary blooD cOvid-19)

Multiple Myeloma

United Kingdom
Imperial College London
British Heart Foundation

Recruiting

Molecular Studies on Hereditary Haemorrhagic Telangiectasia Families

Telangiectasia, Hereditary Hemorrhagic

United Kingdom
Imperial College London

Completed

Study of Histological Samples From Patients With Hereditary Haemorrhagic Telangiectasia

Telangiectasia, Hereditary Hemorrhagic

United Kingdom
Imperial College London
Hammersmith Hospitals NHS Trust

Completed

Investigation of Coagulation Parameters in Hereditary Haemorrhagic Telangiectasia

Telangiectasia, Hereditary Hemorrhagic

United Kingdom
Royal Marsden NHS Foundation Trust

Completed

A Phase II Trial Comparing the Quality of Life, Tolerability and Toxicity of PEG Intron With INTRON® A in Patients With Multiple Myeloma

Multiple Myeloma

United Kingdom
University of Edinburgh
CSL Behring; NHS Lothian

Completed

Fibrinogen as an Alternative to FFP in Aortic Surgery.

Coagulopathy in Patients Having Thoraco-Abdominal Aneurysm Repair

United Kingdom
Novo Nordisk A/S

Completed

Safety of a Single Intravenous Dose of Recombinant Factor XIII in Children With Congenital FXIII A-subunit Deficiency (mentor™4)

Congenital Bleeding Disorder | Congenital FXIII Deficiency

United States, Israel, United Kingdom
The Christie NHS Foundation Trust
CellCentric Ltd.

Not yet recruiting

PatIent exPeRiences and prEFerence of trEatment foR Multiple Myeloma (iPREFER)

Multiple Myeloma

United Kingdom
Imperial College London

Completed

Investigation of Plasma Proteins in Patients With Hereditary Haemorrhagic Telangiectasia and PAVMs

Telangiectasia, Hereditary Hemorrhagic

United Kingdom
Imperial College London

Withdrawn

Study of Endothelial Cells in Patients With Hereditary Haemorrhagic Telangiectasia

Telangiectasia, Hereditary Hemorrhagic

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust
National Institute for Health Research, United Kingdom

Completed

Feasibility of Pre Transplant Exercise (Pre-habilitation) for Multiple Myeloma Patients Awaiting Autologous Stem Cell Transplantation (PREeMPT)

Myeloma

United Kingdom
Royal National Orthopaedic Hospital NHS Trust

Terminated

To Compare Conservative Management Vs. Balloon Kyphoplasty in the Treatment of VCFs in Patients With Multiple Myeloma (MELODY)

Multiple Myeloma

United Kingdom
The Royal Wolverhampton Hospitals NHS Trust
University of Wolverhampton

Recruiting

Zn-DDC to Target Hypoxia-NFkappaB-CSCs Pathway in Multiple Myeloma

Multiple Myeloma

United Kingdom
Prof Jamie Cavenagh
Novartis; Myeloma UK

Unknown

Velcade, Thalidomide, Dexamethasone and Panobinostat Treatment and Panobinostat Maintenance in Multiple Myeloma (MUKsix)

Multiple Myeloma

United Kingdom
University of Liverpool
Genzyme, a Sanofi Company

Unknown

Plerixafor Harvesting And No Chemotherapy for Transplantation of Autologous STem Cells In Cancer (PHANTASTIC) (PHANTASTIC)

Lymphoma | Lymphoproliferative Disorders | Multiple Myeloma | Plasma Cell Dyscrasia

United Kingdom
University College, London

Enrolling by invitation

A New Study Evaluating the Activity of Modular CAR T for mYeloma (MCARTY)

Multiple Myeloma

United Kingdom
Imperial College London

Completed

Hereditary Haemorrhagic Telangiectasia Flight Safety Study (Flying and HHT)

Hereditary Haemorrhagic Telangiectasia

United Kingdom
Imperial College London
The Margaret Hayton HHT Fund

Recruiting

Case Notes Review on Patients With Hereditary Haemorrhagic Telangiectasia

Telangiectasia, Hereditary Hemorrhagic

United Kingdom
University College, London
Cancer Research UK

Recruiting

Biology and Genetics of Smouldering Myeloma (COSMOS)

Multiple Myeloma | MGUS | Smouldering Myeloma

United Kingdom
Institute of Cancer Research, United Kingdom
Royal Marsden NHS Foundation Trust

Recruiting

Myeloma Novel Drug Discovery Ver 1.2 (DISCO)

Multiple Myeloma

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust
University of Copenhagen

Active, not recruiting

Bone Pain in Multiple Myeloma- a Translational Study (BPMM)

Multiple Myeloma

United Kingdom
University of Leeds
Karyopharm Therapeutics Inc; Myeloma UK

Withdrawn

Pembrolizumab Cyclophosphamide and Lenalidomide for Patients With Relapsed Multiple Myeloma (MUKfourteen)

Myeloma Multiple

United Kingdom
University of Liverpool

Not yet recruiting

PuraBond® and Pain Following Resection of Oral or Oropharyngeal Mucosal Lesions (PuraBond PROOF)

Pain | Hemorrhage | Oral Cavity | Hemostatics | Oropharynx

United Kingdom
Riverside Haematology Group

Unknown

Chemotherapy Plus Steroid Therapy in Treating Patients With Multiple Myeloma

Multiple Myeloma and Plasma Cell Neoplasm

United Kingdom
Royal Marsden NHS Foundation Trust
Imperial College London; Institute of Cancer Research, United Kingdom

Active, not recruiting

Machine Learning in Myeloma Response (MALIMAR)

Myeloma

United Kingdom
Medical Research Council

Unknown

Combination Chemotherapy With or Without Cyclophosphamide and Prednisone in Treating Older Patients With Multiple Myeloma

Multiple Myeloma and Plasma Cell Neoplasm

United Kingdom
Acerta Pharma BV
Acerta Pharma, LLC

Completed

An Open-Label, Phase 1b Study of Acalabrutinib With and Without Dexamethasone in Subjects With Multiple Myeloma

Multiple Myeloma (MM)

United States, United Kingdom
Imperial College London

Completed

Frequency of Common Medical Conditions in People With and Without HHT

Hereditary Hemorrhagic Telangiectasia (HHT)

United Kingdom

Clinical Trials on Hemostatic Disorders in United Kingdom

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