Hereditary Haemorrhagic Telangiectasia Flight Safety Study

A Questionnaire Based Study to Evaluate the Safety of Flying in Hereditary Haemorrhagic Telangiectasia (HHT)

Sponsors

Lead Sponsor: Imperial College London

Source Imperial College London
Brief Summary

Hereditary Haemorrhagic Telangiectasia (HHT) is a condition in which sufferers have abnormal blood vessels which makes them more likely to bleed than other people, particularly in the lungs, which results in low blood oxygen levels. Flying may make this worse and cause problems. The investigators want to know if there are an increased number of problems on flights compared to on land.

The investigators currently do not have any evidence based guidelines on air travel to best advice people who suffer with HHT. The investigators would therefore like to ask individuals who have HHT about their experience on a flight, using a postal questionnaire.

Detailed Description

Individuals with Hereditary Haemorrhagic Telangiectasia (HHT) previously reviewed at HHTIC London will be sent an invitation to participate in a short questionnaire study.

Quantitative variables from the questionnaires for statistical analysis will be the number of individuals responding (and number of questionnaires sent out); number of flights taken and number of complications, subgrouped by type, and flight duration in hours. Complication rates will be expressed as proportion of person flight hours.

The quantitative data from the questionnaire will then be compared with quantitative data from patients' medical records using non parametric methods such as Mann Whitney for univariate analyses.

Overall Status Completed
Start Date January 2010
Completion Date October 2011
Primary Completion Date October 2011
Study Type Observational
Primary Outcome
Measure Time Frame
Self reported medical complication During or in 6 weeks post flight
Enrollment 145
Condition
Intervention

Intervention Type: Other

Intervention Name: Aeroplane flight in the past- no active intervention for study

Description: Aeroplane flight(s) previously taken by study participants

Arm Group Label: Pateints with hereditary haemorrhagic telangiectasia

Intervention Type: Other

Intervention Name: Questionnaire

Description: Flight by aeroplane (previous)

Arm Group Label: Pateints with hereditary haemorrhagic telangiectasia

Eligibility

Sampling Method: Non-Probability Sample

Criteria:

Inclusion Criteria:

HHT

Exclusion Criteria:

Unable to provide informed consent

Gender: All

Minimum Age: 16 Years

Maximum Age: N/A

Healthy Volunteers: No

Overall Official
Last Name Role Affiliation
Claire L Shovlin, PhD MA MB BChir FRCP Principal Investigator Imperial College London
Location
Facility: HammersmithHospital, Imperial College Healthcare NHS Trust
Location Countries

United Kingdom

Verification Date

April 2012

Responsible Party

Type: Sponsor

Keywords
Has Expanded Access No
Condition Browse
Arm Group

Label: Pateints with hereditary haemorrhagic telangiectasia

Acronym Flying and HHT
Study Design Info

Time Perspective: Retrospective

Source: ClinicalTrials.gov