Clinical Trials on Hepatic Transplantation

Total 5289 results

Rennes University Hospital

Completed

Pharmacogenetic Study of Tacrolimus in Hepatic Transplant (CYPTAC'H)

Hepatic Transplantation

France
Mansoura University

Completed

Clamp-crush Technique Versus Harmonic Scalpel in Living Donor Hepatectomy (KK_HS)

Hepatic Transplantation

Egypt
Ain Shams University

Active, not recruiting

Bacillus Clausii in Liver Transplantation

Transplantation Infection | Liver Grafting | Hepatic Transplantation

Egypt
University of Wisconsin, Madison

Completed

Glutamine Popsicles in Bone Marrow Transplant (BMT)/Hematopoietic Stem Cell Transplant (HSCT) Patients

Bone Marrow Transplantation | Hematopoietic Stem Cell Transplantion

United States
H. Lundbeck A/S

Completed

Pharmacokinetics Properties of Single Oral Dosing of Lu AE58054 in Subjects With Hepatic Impairment (Mild and Moderate) and in Healthy Subjects

Heptic Impairment

Germany
Johns Hopkins University

Completed

Autoregulation Assessment During Liver Transplantation

Liver Failure | Liver Transplantation | Encephalopathy

United States
Beijing Chao Yang Hospital

Unknown

Effect of Transfusion of Plasma on Endothelial During Liver Transplantation

Liver Transplantation | End Stage Liver DIsease

China
CHIR-Net
University Medicine Greifswald

Completed

Heparin-induced Thrombocytopenia (HIT II) in Liver Transplant Recipients (HITOLT)

Liver Transplantation | Heparin-induced Thrombocytopenia

Germany
Rennes University Hospital

Completed

Evaluation of Hepatic Rigidity by Ultrasonic Impulse Elastography in Liver Transplant Patients (SUPERSONIC)

Hepatic Transplantation

France
Azienda Ospedaliera di Padova

Recruiting

Selection Protocol for Liver Transplantation in Patients Aged Over 70 Years (Over70-LT)

Liver Transplantation | Old Age | End Stage Liver DIsease

Italy
Chang Gung Memorial Hospital

Completed

Supplements SMOF in TPN for Liver Transplantation Recipients

Liver Transplantation | End-stage Liver Disease | Total Parenteral Nutrition

Taiwan
Duke University

Recruiting

A Prospective Registry of Pediatric Cellular Therapy Patients at Risk for Endothelial Dysfunction, Sinusoidal Obstruction Syndrome and/or Multi-Organ Dysfunction Syndrome (MODS).

Hematopoietic Cell Transplantation

United States
Dongguan HEC TaiGen Biopharmaceuticals Co., Ltd.
Peking University People's Hospital

Completed

To Evaluate Efficacy and Safety in TG-2349 Combination With DAG181 (± Ribavirin) in HCV Genotype I Infected Patients

Cirrhosis | Chronic Hepatics C Virus (HCV) Genotype 1 | Non-Cirrhotic | Treatment naïve

China
Astellas Pharma Europe Ltd.

Active, not recruiting

Study to Compare the Pharmacokinetics of Tacrolimus in Stable Pediatric Allograft Recipients Converted From Prograf® to Advagraf®

Liver Transplantation | Kidney Transplantation | Heart Transplantation | Lung Transplantation | Intestine Transplantation

Belgium, Czechia, France, Germany, Italy, Poland, United Kingdom
Astellas Pharma Inc
Astellas Pharma Europe B.V.

Completed

A Study to Evaluate FK778 in Kidney Transplant Patients

Kidney Transplantation | Renal Transplantation | Transplantation, Kidney | Grafting, Kidney | Transplantation, Renal

Belgium, Germany, Spain, Sweden, Italy, Switzerland, United Kingdom, Austria, France, Poland, Czech Republic, Netherlands
Astellas Pharma Europe Ltd.

Completed

A Study to Compare How the Body Absorbs and Processes Two Different Formulations of the Anti-rejection Medication Tacrolimus (Advagraf® or Prograf®) in Children Receiving an Organ Transplant, and How Safe and Effective They Are Over a Longer Period of Time

Liver Transplantation | Kidney Transplantation | Heart Transplantation

Czechia, France, Italy, Poland, United Kingdom
The Hospital for Sick Children

Completed

Pharmacogenetic Trial of Tacrolimus After Pediatric Transplantation

Liver Transplantation | Kidney Transplantation | Heart Transplantation

Canada
Astellas Pharma Europe Ltd.

Terminated

A Paediatric, Open, Follow up Study With Modigraf Examining Safety and Efficacy in de Novo Allograft Recipients (PROGRESSION)

Liver Transplantation | Kidney Transplantation | Heart Transplantation

Belgium, France, Germany, Poland, Spain, United Kingdom
Astellas Pharma Europe Ltd.

Completed

Study to Ascertain if Prolonged Release Tacrolimus (FK506E - MR4) is Safe and Effective When Used in the Long Term and in Combination With Other Immunosuppressive Drugs in Patients Who Have Received a Transplant

Liver Transplantation | Kidney Transplantation | Heart Transplantation

Spain, Australia, France, Germany, Canada, Italy, United Kingdom, Belgium, South Africa, Switzerland, Sweden, United States, Austria, Brazil, Czechia, Denmark, Finland, Hungary, Ireland, Mexico, Netherlands, New Zealand, Poland
Astellas Pharma Europe Ltd.

Completed

A Study to Determine Pharmacokinetics of Children Receiving Modigraf (Tacrolimus Granules) Following Solid Organ Transplantation (OPTION)

Liver Transplantation | Kidney Transplantation | Heart Transplantation

Belgium, France, Germany, Poland, Spain, United Kingdom
Novartis Pharmaceuticals

Completed

Evaluation of Hepatic Function Impairment on the Pharmacokinetics of LEE011

Normal Hepatic Function | Impaired Hepatic Function

United States
Novartis Pharmaceuticals

Completed

Effect of Hepatic Impairment on LDE225..

Normal Hepatic Function | Impaired Hepatic Function

Belgium, Germany, Israel, Bulgaria, United States
Astellas Pharma Inc

Completed

Study to Compare the Pharmacokinetics of Tacrolimus in Adult Transplant Recipients Treated With Advagraf® or Prograf®

Heart Transplantation | Lung Transplantation | Pancreas (Including SPK) Transplantation

France, United Kingdom, Taiwan, Belgium, Italy, Austria
Emory University

Completed

Quality of Life in Pediatric Transplant Recipients

Liver Transplantation | Kidney Transplantation | Heart Transplantation | Lung Transplantation | Heart-Lung Transplantation

United States
Novartis Pharmaceuticals

Completed

Effect of Hepatic Impairment on LDK378 Pharmacokinetics

Normal Hepatic Function | Impaired Hepatic Function

United States
GlycoMimetics Incorporated

Completed

A Study to Evaluate the Effect of IV Doses of Rivipansel in Subjects With Moderate Hepatic Impairment and in Healthy Subjects With Normal Hepatic Function

Moderate Hepatic Impairment | Normal Hepatic Function

United States
Astellas Pharma Europe B.V.
Medivation, Inc.

Completed

A Study to Investigate the Effect of Severely Diminished Liver Function on the Metabolism, Safety, and Tolerability of a Single Oral Dose of Enzalutamide in Men

Severe Hepatic Impairment | Normal Hepatic Function

Bulgaria
Pfizer

Completed

Pharmacokinetics Of Orally Administered Fx-1006A In Subjects With Hepatic Dysfunction

Mild Hepatic Dysfunction | Moderate Hepatic Dysfunction

South Africa
Hong Kong Children's Hospital

Recruiting

Ultrasound Measurements of Hepatic Vasculatures and Hepatic Doppler Assessment of Healthy Children

Portal Vein | Hepatic Veins | Hepatic Artery | Liver Circulation

Hong Kong
Pfizer

Recruiting

A Study to Learn About the Study Medicine (Called Lorlatinib) in People With Liver Dysfunction

Healthy Volunteers | Moderate Hepatic Impairment | Severe Hepatic Impairment

United States
Novartis

Completed

Conversion Trial From Mycophenolate Mofetil (MMF) to Enteric-coated Mycophenolate Sodium (EC-MPS) in Stable Transplanted Patients Suffering From Gastrointestinal (GI) Adverse Events While on Mycophenolate Mofetil Therapy (MMF) Therapy

Liver Transplantation | Kidney Transplantation

Switzerland
University of Wisconsin, Madison

Terminated

Cytokine Kinetics Test to Assess the Presence or Absence of Tolerance in Organ Transplant

Liver Transplantation | Kidney Transplantation

United States
Nantes University Hospital

Unknown

A Study To Compare Sirolimus Versus Tacrolimus In De Novo Simultaneous Pancreas- Kidney Allograft Recipients Receiving An Induction Therapy With Antithymocyte Globulin Plus Mycophenolate Mofetil Plus Corticosteroids

Kidney Transplantation | Pancreas Transplantation

France
University Hospital, Gasthuisberg
Juvenile Diabetes Research Foundation; Fund for Scientific Research, Flanders...

Unknown

Insulin Secretory Capacity in Insulin-independent Pancreas-Kidney Recipients Compared to Controls

Kidney Transplantation | Pancreas Transplantation

Belgium
National Taiwan University Hospital

Unknown

Sirolimus Blood Concentrations on Conversion From Oral Solution to Tablets

Kidney Transplantation | Immunosuppression | Transplantation

Taiwan
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Treg Cell Therapy in Liver and Kidney Transplantation - Preclinical Validation of Batches of Treg Cells Amplified in Vitro (PRE-TREG)

Liver Transplantation | Kidney Transplantation

France
Emory University

Recruiting

Immune Monitoring and Assay Development in Organ Transplant Recipients (IMP)

Organ Transplantation | Transplantation Immunology

United States
Astellas Pharma China, Inc.

Completed

A Study to Evaluate the Safety and Efficacy of a Modigraf® Based Immunosuppression Regimen in De Novo Pediatric Allograft Liver and Kidney Transplantation Recipients

Liver Transplantation | Kidney Transplantation

China
Astellas Pharma China, Inc.

Completed

A Study of Modigraf® (Tacrolimus Granules) to Evaluate the Pharmacokinetics and Long-term Safety and Efficacy in De Novo Pediatric Allograft Liver and Kidney Transplantation Recipients

Liver Transplantation | Kidney Transplantation

China
University of Nebraska

Completed

Pre-operative Evaluation of Kidney & Pancreas Transplant Patients

Kidney Transplantation | Pancreas Transplantation

United States
Rennes University Hospital

Completed

Impact of P-gp, MRP2, ENT-1 and CNT3 on the Blood Concentration / Intra-PBMC Concentration of Tacrolimus (TRANS-TAC)

Liver Transplantation | Kidney Transplantation

France
Bristol-Myers Squibb

Completed

Pattern Of Use Of Belatacept In US Transplant Recipients

Kidney Transplantation: Transplantation, Kidney
Helsinki University Central Hospital
Tampere University Hospital

Completed

Immunogenicity of 13-valent Pneumococcal Conjugate Vaccine Compared to the Pneumococcal Polysaccharide Vaccine in Adult Kidney and Liver Transplant Patients (SOT13)

Liver Transplantation | Kidney Transplantation

Finland
National Taiwan University Hospital

Unknown

The Influence of ABCB1、CYP3A4、CYP3A5、POR Genetic Polymorphism and Other Factors on Tacrolimus Blood Concentration

Liver Transplantation | Kidney Transplantation

Taiwan
Astellas Pharma Inc

Completed

A Study to Demonstrate Safety and Efficacy of Advagraf in Patients Undergoing Kidney or Liver Transplantation in India

Liver Transplantation | Kidney Transplantation

India
University of Manchester
Manchester University NHS Foundation Trust

Unknown

CEUS in Kidney and Pancreas Transplantation

Kidney Transplantation | Pancreas Transplantation

United Kingdom
National Taiwan University Hospital
National Science Council, Taiwan

Unknown

Organ Transplantation Rehabilitation: Effect of Bedside Exercise Device and Activity Reinforcement

Liver Transplantation | Heart Transplantation

Taiwan
University of Oslo School of Pharmacy

Completed

Intracellular and Renal/Myocardial Tissue Concentrations of Cyclosporine A (CsA) and Rejection Frequency Following Transplantation

Heart Transplantation | Renal Transplantation

Norway
Nantes University Hospital

Terminated

Protocol DIVAT-Uro

Kidney Transplantation | Pancreas-kidney Transplantation

France
Hospices Civils de Lyon

Completed

Bile Acids and Incretins in Pancreas Kidney Transplant Patients (ITABI)

Kidney Transplantation | Pancreas-kidney Transplantation

France

Clinical Trials on Hepatic Transplantation

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