Clinical Trials on Hepatic Failure in India

Total 230 results

All India Institute of Medical Sciences, New Delhi

Unknown

Therapeutic Efficacy of L-Ornithine L-Aspartate Infusion in Patients With Acute Liver Failure

Acute Liver Failure

India
Institute of Liver and Biliary Sciences, India

Completed

Efficacy of Granulocyte Colony-stimulating Factor and Erythropoetin for Patients With Acute-on-chronic Liver Failure

Acute on Chronic Hepatic Failure

India
Institute of Liver and Biliary Sciences, India

Not yet recruiting

Efficacy of L-ornithine L-aspartate and Therapeutic Plasma Exchange Versus Plasma Exchange Alone in Lowering Ammonia and Improving Outcomes in Pediatric Acute Liver Failure.

Liver Failure, Acute

India
Institute of Liver and Biliary Sciences, India

Completed

High-Volume Plasma Exchange Versus Standard Medical Treatment in Patients With Acute Liver Failure

Acute Liver Failure

India
Institute of Liver and Biliary Sciences, India

Withdrawn

To Assess the Role of Fecal Microbiota Transplant in Acute Liver Failure

Acute Liver Failure

India
Postgraduate Institute of Medical Education and...

Completed

Intravenous Branched Chain Amino Acids for Hepatic Encephalopathy in ACLF (BCAA-ACLF)

Acute-On-Chronic Liver Failure | Hepatic Encephalopathy

India
Postgraduate Institute of Medical Education and...

Unknown

PEG3350 in ACLF With Hepatic Encephalopathy

Acute-On-Chronic Liver Failure | Hepatic Encephalopathy

India
Post Graduate Institute of Medical Education and...
All India Institute of Medical Sciences, Bhubaneswar; Asian Institute of Gastroenterology... and other collaborators

Recruiting

Intravenous BCAA for HE in ACLF (BCAA-HE-ACLF)

Acute-On-Chronic Liver Failure | Hepatic Encephalopathy

India
Postgraduate Institute of Medical Education and...

Recruiting

Immune Profile, Neuronal Dysfunction, Metabolomics and Ammonia in Therapeutic Response of HE in ACLF

Decompensated Cirrhosis | Acute-On-Chronic Liver Failure | Hepatic Encephalopathy

India
Postgraduate Institute of Medical Education and...

Recruiting

20% Albumin vs. Balanced Salt Solution as Resuscitation Fluid in Cirrhosis With Sepsis Induced Hypotension

Acute-On-Chronic Liver Failure | Shock, Septic | Cirrhosis, Liver | Shock Hypovolemic

India
Asian Institute of Gastroenterology, India

Unknown

Use of HA 330-II for Hemofiltration in Patients With ALF as a Bridge to Liver Transplantation .

Acute-On-Chronic Liver Failure

India
Govind Ballabh Pant Hospital

Unknown

Granulocyte Colony Stimulating Factor(G-CSF) Therapy for Patients With ACLF

Acute on Chronic Liver Failure

India
Institute of Liver and Biliary Sciences, India

Not yet recruiting

Prognostic Significance of Acute Change in Liver and Splenic Stiffness in Patients of Acute on Chronic Liver Failure

Acute on Chronic Liver Failure

India
All India Institute of Medical Sciences, New Delhi

Unknown

A Trial of Ribavirin in Patients With ACLF Due to Hepatitis E Virus (HEVRibavirin)

Liver Failure | Acute on Chronic Hepatic Failure | Hepatitis E Infection

India
Institute of Liver and Biliary Sciences, India

Not yet recruiting

To Determine the Predictors of Reversibility for Acute-on-Chronic Liver Failure at 6-months.

Acute-On-Chronic Liver Failure

India
Institute of Liver and Biliary Sciences, India

Not yet recruiting

Acute hemodynamiC Response To Carvedilol Predicts Survival in ACLF Patients

Acute-On-Chronic Liver Failure

India
Institute of Liver and Biliary Sciences, India

Completed

To Study the Immunomodulating Effects and Safety Profile of ω3 and ω6 PUFA Containing Intravenous Lipid Emulsion in Patients With Acute on Chronic Liver Failure

Chronic Liver Failure

India
Institute of Liver and Biliary Sciences, India

Withdrawn

High Volume Plasmapheresis for Refractory Hepatic Encephalopathy in Liver Intensive Care Unit.

Refractory Hepatic Encephalopathy

India
Institute of Liver and Biliary Sciences, India

Recruiting

Acute Hemodynamic Response to Carvedilol in Predicting Survival in Acute on Chronic Liver Failure Patients - A Pilot Study.

Acute on Chronic Liver Failure

India
Institute of Liver and Biliary Sciences, India

Unknown

Efficacy of Albumin Plus Midodrine v/s Albumin Alone in Reducing Incidence of Paracentesis Induced Circulatory Dysfunctions in ACLF Patients.

Acute-On-Chronic Liver Failure

India
Institute of Liver and Biliary Sciences, India

Completed

Incidence And Outcome Of Paracentesis Induced Circulatory Dysfunction In Acute-On-Chronic Liver Failure.

Acute on Chronic Liver Failure

India
Institute of Liver and Biliary Sciences, India

Completed

Role of 13C Methacetin Breath Test in Predicting Prognosis Among Patients With Acute or Acute on Chronic Liver Failure (ACLF).

Acute Liver Failure | Acute on Chronic Liver Failure

India
Institute of Liver and Biliary Sciences, India

Not yet recruiting

To Study the Role of Plasma Von Willebrand Factor Antigen (vWF) to A Disintegrin-like and Metalloproteinase With Thrombospondin Type-1 Motifs 13 (ADAMTS-13) Activity Ratio as a Predictor of Development of Extrahepatic Organ Failure in Acute on Chronic Liver Failure (ACLF) Patients.

Acute on Chronic Liver Failure

India
Institute of Liver and Biliary Sciences, India

Unknown

Efficacy of Albumin Therapy With Standard Medical Treatment (SMT) as Compared to Standard Medical Treatment (SMT) in Improving Patient Survival and Immune Modulation in Patients With Acute on Chronic Liver Failure (ASIA Trial).

Acute on Chronic Liver Failure

India
Institute of Liver and Biliary Sciences, India

Unknown

Efficacy and Safety of Hemoperfusion or Plasma Exchange Compared to Standard Medical Therapy in Patients With Acute on Chronic Liver Failure

Acute-On-Chronic Liver Failure

India
Institute of Liver and Biliary Sciences, India

Withdrawn

To Assess the Efficacy of High-Volume Plasma Exchange and GCSF Versus GCSF Alone in Patients of Acute on Chronic Liver Failure (ACLF).

Acute-On-Chronic Liver Failure

India
Institute of Liver and Biliary Sciences, India

Terminated

To Study the Influence of GCSF on Natural History of Acute On Chronic Liver Failure After the Acute Phase

Acute on Chronic Liver Failure

India
Institute of Liver and Biliary Sciences, India

Completed

High Volume Plasma Exchange in Children With Acute Liver Failure and Acute on Chronic Liver Failure

Acute Liver Failure

India
Postgraduate Institute of Medical Education and...

Completed

Effect of Lactulose on Minimal Hepatic Encephalopathy and Health-Related Quality of Life

Hepatic Encephalopathy | Minimal Hepatic Encephalopathy

India
Postgraduate Institute of Medical Education and...

Unknown

Efficacy of Sildenafil in the Improvement of Cognition and Quality of Life in Patients With Cirrhosis of Liver. A Proof of Concept Study.

Hepatic Encephalopathy.

India
Institute of Liver and Biliary Sciences, India

Completed

Bowel Colonization With Multi-drug Resistant Bacterial Species in Hospitalized Patients With acute-on Chronic Liver Failure (ACLF), and Its Relationship With Extra-intestinal Infectious Events and Short-term Outcomes.

Acute-On-Chronic Liver Failure

India
Postgraduate Institute of Medical Education and...

Completed

Global Coagulation Assessment in Cirrhosis and ACLF

Acute-On-Chronic Liver Failure | Cirrhosis, Liver

India
Institute of Liver and Biliary Sciences, India

Not yet recruiting

Lactate Kinetics as a Predictor of Survival in ACLF With Septic Shock

Acute on Chronic Liver Failure

India
Institute of Liver and Biliary Sciences, India

Completed

Assessment of Coagulation Profile and Haematopoietic Responses in Patients With Acute-on-chronic Liver Failure During Systemic Inflammatory Response (SIRS) and Sepsis

Acute on Chronic Liver Failure

India
Institute of Liver and Biliary Sciences, India

Not yet recruiting

An Open-label Randomized Controlled Trial Comparing the Role of Therapeutic Plasma-exchange in Ameliorating Secondary Organ Dysfunctions in Patients With ACLF and Develop Biomarkers of Treatment Response

Acute on Chronic Liver Failure

India
Institute of Liver and Biliary Sciences, India

Completed

Effect of Goal Directed Ammonia Lowering Therapy in Acute on Chronic Liver Failure Patients With Hepatic Encephalopathy.

Acute-On-Chronic Liver Failure

India
All India Institute of Medical Sciences, New Delhi

Unknown

Assessment of Coagulation Abnormalities in Acute on Chronic Liver Failure Patients Using Thromboelastography

Cirrhosis | Acute on Chronic Liver Failure

India
Institute of Liver and Biliary Sciences, India

Recruiting

To Compare Relaxed Rotational Thromboelastometry Cut-offs With Standard Cut-offs for Guiding Blood Product Use Before Invasive Procedures in Cirrhosis and Acute on Chronic Liver Failure Patients

Liver Cirrhosis | Acute on Chronic Liver Failure

India
Abbott

Completed

A Retrospective, Open-label, Uncontrolled Cohort Study to Assess the Effectiveness and Safety of Lactulose Retention Enema in the Treatment of Cirrhotic Patients With Grade 3 or 4 (West Haven Criteria) Hepatic Encephalopathy (HE) [The RETRO Study]

Hepatic Encephalopathy

India
Govind Ballabh Pant Hospital

Unknown

Trial Comparing Sedation for Endoscopy With Propofol Versus Midazolam in Cirrhotics

Hepatic Encephalopathy

India
Institute of Liver and Biliary Sciences, India

Completed

Spectrum, Profile and Outcome of Infections in Patients With Cirrhosis and/ or Acute on Chronic Liver Failure

Cirrhosis | Chronic Liver Failure | Acute Liver Failure

India
Institute of Liver and Biliary Sciences, India

Completed

Rifaximin Plus Lactulose Versus Lactulose Alone for the Treatment of Hepatic Encephalopathy: a Double Blind Randomized Trial

Hepatic Encephalopathy

India
Institute of Liver and Biliary Sciences, India

Recruiting

Role of Fecal Microbiota in Predicting Graft Rejection and Sepsis Among Recipients of Living Donor Liver Transplant in First Year.

Liver Cirrhosis | Acute-On-Chronic Liver Failure | Acute Liver Failure

India
CD Pharma India Pvt. Ltd.
Postgraduate Institute of Medical Education and Research

Completed

Secondary Prophylaxis of Hepatic Encephalopathy With a Probiotic Preparation (VSL#3)

Hepatic Encephalopathy

India
Institute of Liver and Biliary Sciences, India

Withdrawn

To Study and Compare the Clinical Course and Development of Organ Failure in Severe Acute Hepatitis Without Ascites, Non-cirrhotic and Cirrhotic Patients With Ascites [Acute on Chronic Liver Failure] and Acute Deterioration of Previously Decompensated Cirrhosis.

Cirrhosis

India
Institute of Liver and Biliary Sciences, India

Not yet recruiting

To Evaluate the Safety and Efficacy of Preemptive Administration of Continuous Renal Replacement Therapy in Patients With Acute Liver Failure With Cerebral Edema

Acute Liver Failure

India
Postgraduate Institute of Medical Education and...

Recruiting

Anti-fungal Strategies in Acute-on-Chronic Liver Failure Patients

Acute-On-Chronic Liver Failure | Mycoses | Invasive Fungal Infections | Antifungal Agents

India
Institute of Liver and Biliary Sciences, India

Completed

Role of Hypertonic Saline Versus Mannitol in the Management of Raised Intracranial Pressure in Patients With ALF

Acute Liver Failure

India
Institute of Liver and Biliary Sciences, India

Completed

Utility of Liver and Splenic Stiffness in Predicting Esophageal Varices in Patients With Acute on Chronic Liver Failure

Acute-On-Chronic Liver Failure

India
Institute of Liver and Biliary Sciences, India

Completed

Efficacy of Nonselective Beta Blocker vs Placebo in Patients With Acute-on-chronic Liver Failure With Small/ no Esophageal Varices

Acute on Chronic Liver Failure

India

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