Clinical Trials on Hepatic Transplantation

Total 5320 results

Hospices Civils de Lyon

Completed

Bile Acids and Incretins in Pancreas Kidney Transplant Patients (ITABI)

Kidney Transplantation | Pancreas-kidney Transplantation

France
Novartis

Completed

Everolimus in a Cyclosporine Microemulsion-free Regimen Compared to a Low-dose Cyclosporine Microemulsion Regimen, in de Novo Kidney Transplant Patients (CERTES02)

Organ Transplantation, Renal Transplantation
National Institute of Allergy and Infectious Diseases...
Clinical Trials in Organ Transplantation

Terminated

Optimization of NULOJIX® Usage As A Means of Avoiding CNI and Steroids in Renal Transplantation

Kidney Transplantation | Renal Transplantation

United States
National Taiwan University Hospital

Unknown

The Pharmacokinetics of Sirolimus When Combined With Cyclosporine or Tacrolimus in Renal Transplant Patients

Kidney Transplantation | Immunosuppression | Transplantation

Taiwan
Assistance Publique - Hôpitaux de Paris

Unknown

Patients' Outcome With Severe or Fulminant Hepatic Insufficiency, Hospitalized in the Public Hospitals of Paris (DEVINHEF)

Fulminating Hepatic Failure

France
Bristol-Myers Squibb

Completed

Study Comparing the Safety and Efficacy of Belatacept With That of Cyclosporine in Patients With a Transplanted Kidney

Kidney Transplantation | Graft Rejection | Renal Transplantation

United States
National Center for Complementary and Integrative...
National Cancer Institute (NCI)

Completed

The Effects of Music Therapy-Based Stress Reduction on Bone Marrow Transplant Recipients

Stem Cell Transplantation | Bone Marrow Transplantation

United States
Vital Therapies, Inc.

Completed

Phase 2 Evaluation of the ELAD System in the Management of Acute Liver Failure

Fulminant Hepatic Failure

United States
Vital Therapies, Inc.

Withdrawn

Safety and Efficacy of the Extracorporeal Liver Assist Device (ELAD®) In Patients With Fulminant Hepatic Failure (FHF) (ELAD)

Fulminant Hepatic Failure

United States
University of North Carolina, Chapel Hill
Mallinckrodt

Withdrawn

Acthar for Treatment of Post-transplant FSGS

Kidney Transplantation | Renal Transplantation | FSGS

United States
Eisai Inc.

Completed

A Pharmacokinetic and Safety Study of E7080 in Subjects With Mild (10 mg), Moderate (10 mg), and Severe Hepatic Impairment (5 mg) and Normal Hepatic Function (10 mg)

Hepatic Impairment | Hepatic Function

United States
Agios Pharmaceuticals, Inc.

Completed

A Pharmacokinetic Study of Mitapivat in Participants With Moderate Hepatic Impairment Compared to Matched Healthy Control Participants With Normal Hepatic Function

Moderate Hepatic Impairment

United States
Medical College of Wisconsin

Terminated

Quality of Life in Pediatric Transplant Patients

Liver Transplantation | Kidney Transplantation | Heart Transplantation

United States
Genentech, Inc.
Pfizer; Novartis Pharmaceuticals; Mylan Pharmaceuticals Inc; Sandoz; Roxane Laboratories and other collaborators

Recruiting

The Mycophenolate Pregnancy Registry

Heart Transplantation, Kidney Transplantation, Liver Transplantation, Autoimmune Diseases

United States
Hospital Israelita Albert Einstein

Recruiting

Impact of Yoga and Gentle Massage Practices on Symptom Management in Patients Undergoing HSCT (Yoga)

Bone Marrow Transplantation | Hematopoietic Stem Cell Transplantation

Brazil
National Institute of Allergy and Infectious Diseases...
PPD; Rho Federal Systems Division, Inc.; Immune Tolerance Network (ITN)

Active, not recruiting

Tolerance by Engaging Antigen During Cellular Homeostasis (TEACH)

Kidney Transplantation | Renal Transplantation | Renal Transplant Recipient

United States
Merck Sharp & Dohme LLC

Completed

Belzutifan (MK-6482) Hepatic Impairment Study (MK-6482-020)

Moderate Hepatic Impairment

United States
EQRx International, Inc.

Completed

An Open-Label, Single-Dose, Parallel-Group Study of the Pharmacokinetics and Safety of EQ143

Severe Hepatic Impairment

United States
Pfizer

Completed

Evaluate Severe Hepatic Impairment on Dacomitinib PK

Severe Hepatic Impairment

United States
Takeda

Completed

Pharmacokinetics, Safety and Tolerability of Vortioxetine in Normal Hepatic Function or Severe Hepatic Impairment

Severe Hepatic Impairment

United States
Merck Sharp & Dohme LLC

Not yet recruiting

A Study of Nemtabrutinib in Participants With Moderate Hepatic Impairment (MK-1026-015)

Hepatic Impairment (HI)
Bausch Health Americas, Inc.

Terminated

Steady-State Pharmacokinetics of Rifaximin 550 mg Tablets in Healthy and Hepatically Impaired Subjects

Severe Hepatic Impairment

United States
Janssen Research & Development, LLC

Completed

A Study to Assess the Effects of Hepatic Impairment on the Pharmacokinetics, Safety, and Tolerability of Intranasally Administered Esketamine

Hepatic Impairment | Normal Hepatic Function

United States
University of Pittsburgh

Recruiting

Biomarkers in Transplant Recipients to Improve Outcomes

Bone Marrow Transplantation | Solid Organ Transplantation

United States
Johns Hopkins University

Completed

A Study of mDOT for Immunosuppressant Adherence in Solid Organ Transplant Recipients

Liver Transplantation | Medication Adherence | Kidney Transplantation

United States
Cardiox Corporation

Terminated

Liver Function Assessment - Feasibility and Dosing Study

Hepatic Failure
University Hospital, Geneva

Recruiting

Precision Dosing of Busulfan in Children Undergoing HSCT (BuGenes01)

Allogeneic Hematopoietic Stem Cell Transplantation | Hematopoietic Stem Cell Transplantation | Autologous Hematopoietic Stem Cell Transplantation

Switzerland
Astellas Pharma Inc
Astellas Pharma Taiwan, Inc.

Completed

A Randomized Study to Assess the Safety and Efficacy of Prograf vs Prograf-XL in de Novo Liver Transplant Recipients.

Liver Transplantation | Transplantation Immunology | Host vs Graft Reaction

Taiwan
Astellas Pharma Europe Ltd.

Completed

A Study to Compare the Finger Prick Whole Blood MITRA Assay Method With the Established Venepuncture Whole Blood Method for Quantitative Determination of Tacrolimus Blood Concentrations in Transplant Patients (MITRA)

Liver Transplantation | Kidney Transplantation

France, United Kingdom
Astellas Pharma Inc
Astellas Pharma Taiwan, Inc.

Completed

A Randomized Study to Assess the Safety and Efficacy of Prograf vs Prograf-XL in de Novo Kidney Transplant Recipients

Kidney Transplantation | Transplantation Immunology | Host vs Graft Reaction

Taiwan
Medical University of Vienna

Unknown

Sirolimus Based Immunosuppression for Patients Undergoing Kidney Transplantation in the Eurotransplant Senior Program (ESP)

Kidney Function After Transplantation | Outcome After Kidney Transplantation
University Hospital, Strasbourg, France

Recruiting

Hydrodissection of the Hepatoduodenal Ligament (Duodenal)

Hepatic Lesions

France
Maastricht University

Completed

Liver Glycogen Dynamics (LGD)

Hepatic Glycogen

Netherlands
Shire

Completed

Pharmacokinetics (PK) of 20 mg Teduglutide in Participants With Moderately Impaired Hepatic Function Compared to Healthy Participants

Hepatic Impairment

United States
University of Michigan Rogel Cancer Center

Completed

Assessment Of Liver Function in Patients Undergoing Hepatic Irradiation (IC-Green)

Hepatic Irradiation

United States
Assiut University

Unknown

Implication of Fluid Strategies Upon Hepatic Outcome in Hepatobiliary Surgery

Hepatic Complication
KBP Biosciences
Covance

Completed

Pharmacokinetics of KBP-5074 in Patients With Moderate Hepatic Impairment

Healthy | Moderate Hepatic Impairment

United States
Centre Hospitalier Universitaire de Nice

Completed

Pyrophosphate Homeostasis and Hepatic Expression of ABCC6.Pyro-TH (Pyro-TH)

Hepatic Failure

France
Rennes University Hospital

Completed

Comparison of the Variability of Hepatic Load Quantification in Iron and Fat Estimated by MRI at 1.5 and 3 Tesla (HEMOCOMPARE)

Iron Hepatic Overload | Fat Hepatic Overload

France
Biotie Therapies Inc.
Acorda Therapeutics

Terminated

Study to Investigate the Influence of Hepatic Insufficiency on the Pharmacokinetics of Tozadenant

Hepatic Impairment

United States
Tibotec BVBA

Completed

A Study of TMC207 in Patients With Moderately Impaired Hepatic Function

Moderate Hepatic Impairment
Pfizer
Medivation, Inc.

Completed

Study To Evaluate The Pharmacokinetics, Safety, And Tolerability Of Dimebon [Pf-01913539] In Subjects With Hepatic Impairment And Normal Hepatic Function

Hepatic Failure

United States
Novartis Pharmaceuticals

Completed

Pharmacokinetic Study of Icenticaftor in Participants With Hepatic Impairment

Hepatic Failure

United States
Daiichi Sankyo, Inc.

Completed

A Study of Quizartinib Pharmacokinetics in Participants With Moderate Hepatic Impairment

Hepatic Impairment | Moderate Impaired Hepatic Function

United States
Mitsubishi Tanabe Pharma Corporation

Completed

PK Study in Subjects With Severe Hepatic Impairment (MCI-186-E05 HP)

Healthy | Severe Hepatic Impairment

Czechia, Hungary, Slovakia
Astellas Pharma Korea, Inc.

Completed

A Single Center, Open-label, Randomized, Pilot Study to Evaluate the Safety and Efficacy of a Tacrolimus Modified Release, ADVAGRAF®, Versus Tacrolimus Twice Daily, PROGRAF® in Stable Renal Recipients (SINGLE)

Kidney Transplantation | Renal Transplantation | Stable Renal Recipients

Korea, Republic of
AdventHealth

Completed

Endoscopic Ultrasound Guided Liver Biopsy

Hepatic Cancer | Hepatic Carcinoma | Hepatic Neoplasm

United States
Jazz Pharmaceuticals

Completed

Assessment of the Single Dose Pharmacokinetics and Tolerability of Sativex in Patients With Impaired Hepatic Function and Healthy Patients

Hepatic Impairment

United States
Seagen Inc.

Completed

A Safety Study of Tucatinib in Healthy and Hepatically-Impaired Subjects

Hepatic Impairment

United States
Nuh Rahbari

Completed

Stapler Hepatectomy for Elective Liver Resection (CRUNSH)

Hepatic Resection

Germany

Clinical Trials on Hepatic Transplantation

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