Clinical Trials on Hepatocellular Carcinoma (HCC) in United States

Total 10970 results

Medical College of Wisconsin
Northwestern University; Guerbet

Completed

Can Quantitative MRI After cTACE Help Predict Survival ?

Hepatocellular Carcinoma (HCC)

United States
Indiana University

Terminated

Y90 Radiation Segmentectomy vs SBRT for HCC (SBRT vs Y90)

Hepatocellular Carcinoma (HCC)

United States
Bayer

Not yet recruiting

A First-in-Human Study to Learn About How BAY3630942 is Distributed and Processed Inside the Body When Given After BAY3547922 and How Safe it is in People With Liver Cancer

Hepatocellular Carcinoma (HCC)

United States
University of Alabama at Birmingham

Completed

A Pilot Study of Trans Arterial Chemoembolization (TACE), Followed by Stereotactic Radiation Therapy (SBRT) for Patients With Hepatocellular Carcinoma (RAD 0902)

Hepatocellular Carcinoma (HCC)

United States
Sidney Kimmel Cancer Center at Thomas Jefferson...
Pfizer

Active, not recruiting

A Clinical Research Study to Determine Whether PD 0332991 May Be Effective in Treating Patients With Liver Cancer

HCC | Advanced Hepatocellular Carcinoma | Liver Cancer

United States
Abramson Cancer Center of the University of Pennsylvania

Completed

Galunisertib (LY2157299) Plus Stereotactic Body Radiotherapy (SBRT) in Advanced Hepatocellular Carcinoma (HCC)

ADVANCED HEPATOCELLULAR CARCINOMA (HCC)

United States
Delcath Systems Inc.

Withdrawn

Sequential Melphalan for Use With Hepatic Delivery System Treatment Followed by Sorafenib in Patients With Unresectable HCC

Hepatocellular Carcinoma (HCC)

United States
Icahn School of Medicine at Mount Sinai

Completed

Post Sustained Virological Response (SVR) Hepatocellular Carcinoma (HCC) Screening

HCC | Hepatocellular Carcinoma | Hepatitis C | HCV

United States
MedImmune LLC

Completed

MEDI-573 in Combination With SOC in Unresectable or Metastatic HCC. (MEDI-573-1028)

Unresectable or Metastatic Hepatocellular Carcinoma (HCC)

United States
University of California, Irvine
Exelixis

Recruiting

Cabozantinib Combined With Ipilimumab/Nivolumab and TACE in Patients With Hepatocellular Carcinoma

HCC | Hepatocellular Carcinoma

United States
Lahey Clinic
Varian Medical Systems

Completed

Stereotactic Body Radiation Therapy (SBRT) Versus Trans-Arterial Chemoembolization (TACE) as Bridge to Liver Transplant (SBRTvsTACE)

HCC | Hepatocellular Carcinoma

United States
University of Texas Southwestern Medical Center
University of Michigan

Recruiting

CEUS vs. AMRI for HCC Detection in Patients With Indeterminate Liver Nodules

HCC | Hepatocellular Carcinoma

United States
Icahn School of Medicine at Mount Sinai

Completed

Evaluation of Liver Cancer With Magnetic Resonance Imaging (MRI)

HCC | Hepatocellular Carcinoma

United States
AstraZeneca

Recruiting

A US Study to Evaluate Transarterial Radioembolization (TARE) in Combination With Durvalumab and Bevacizumab Therapy in People With Unresectable Hepatocellular Carcinoma Amenable to TARE (EMERALD-Y90)

Hepatocellular Carcinoma (HCC)

United States
Shanghai Junshi Bioscience Co., Ltd.

Active, not recruiting

Phase III Study of Toripalimab（JS001） Combined With Lenvatinib for Advanced HCC

Advanced Hepatocellular Carcinoma (HCC)

Italy, Poland, Singapore, United States, China, Ukraine
Bristol-Myers Squibb

Completed

A Phase II Open Label Study of BMS-582664 in Locally Advanced or Metastatic Hepatocellular Cancer

Hepatocellular Carcinoma (HCC)

France, Korea, Republic of, Taiwan, United States, Singapore, Philippines, Malaysia, Hong Kong
Suzhou Kintor Pharmaceutical Inc,

Active, not recruiting

GT90001 Plus Nivolumab in Patients With Advanced Hepatocellular Carcinoma

HCC | Hepatocellular Carcinoma

United States
Astellas Pharma Inc

Terminated

A Randomized, Placebo-controlled, Double-blind Phase 2 Study With OSI-906 in Patients With Advanced HCC

Advanced Hepatocellular Carcinoma (HCC)

Korea, Republic of, Belgium, United States, Hong Kong, Singapore, Taiwan, Germany, Spain, France, Italy
Novartis Pharmaceuticals

Completed

FGF401 in HCC and Solid Tumors Characterized by Positive FGFR4 and KLB Expression

Hepatocellular Carcinoma (HCC) | Solid Malignancies

United States, Germany, Taiwan, Spain, Singapore, France, Japan, Korea, Republic of, Hong Kong, China, Italy
Blueprint Medicines Corporation

Completed

A Phase 1 Study of Fisogatinib (BLU-554) in Patients With Hepatocellular Carcinoma

Hepatocellular Carcinoma (HCC)

China, Korea, Republic of, Taiwan, Hong Kong, United Kingdom, United States, France, Spain, Switzerland, Singapore, Germany, Italy
Icahn School of Medicine at Mount Sinai
National Cancer Institute (NCI); University of California, San Diego; University... and other collaborators

Enrolling by invitation

FAST (Focused Abbreviated Screening Technique)-MRI Study

Liver Cirrhosis | Hepatocellular Carcinoma (HCC)

United States
Lahey Clinic
Varian Medical Systems; Merit Medical Systems, Inc.

Active, not recruiting

Stereotactic Body Radiation Therapy (SBRT) vs Trans-Arterial Chemoembolization (TACE) as Bridge to Transplant (SBRTvsTACE)

HCC | Hepatocellular Carcinoma

United States, Canada
BeiGene

Completed

Phase 3 Study of Tislelizumab Versus Sorafenib in Participants With Unresectable HCC

Hepatocellular Carcinoma (HCC)

China, Italy, United States, Germany, Japan, Taiwan, Czechia, Spain, United Kingdom, France, Poland
Eisai Limited
Merck Sharp & Dohme LLC

Completed

A Multicenter, Open-Label, Phase 3 Trial to Compare the Efficacy and Safety of Lenvatinib (E7080) Versus Sorafenib in First-line Treatment of Participants With Unresectable Hepatocellular Carcinoma

Hepatocellular Carcinoma (HCC)

Italy, Korea, Republic of, Poland, United States, Australia, Belgium, Canada, China, France, Germany, Hong Kong, Israel, Japan, Malaysia, Philippines, Russian Federation, Singapore, Spain, Taiwan, Thailand, United Kingdom
Nerviano Medical Sciences

Active, not recruiting

Study on Safety and Efficacy of NMS-01940153E in Adult Patients With Unresectable Hepatocellular Carcinoma (HCC) Previously Treated With Systemic Therapy

Unresectable Hepatocellular Carcinoma (HCC)

Italy, Spain, United States
Kathy Miller
Millennium Pharmaceuticals, Inc.; Big Ten Cancer Research Consortium

Terminated

MLN0128 Compared to Sorafenib in Advanced or Metastatic Hepatocellular Carcinoma

HCC | Hepatocellular Carcinoma | Liver Cancer

United States
BeiGene

Completed

Study of BGB-A317 in Participants With Previously Treated Unresectable HCC

Hepatocellular Carcinoma (HCC)

Spain, China, Taiwan, Germany, Italy, United Kingdom, France, Poland
Eureka Therapeutics Inc.

Recruiting

ET140203 T Cells in Pediatric Subjects With Hepatoblastoma, HCN-NOS, or Hepatocellular Carcinoma (ARYA-2)

Liver Neoplasms | Hepatocellular Carcinoma (HCC) | Liver Cancer | Hepatoblastoma | Metastatic Liver Cancer | HEMNOS

United States
Chugai Pharmaceutical

Completed

A Phase I Study of GC33 in Advanced or Metastatic Liver Cancer (Hepatocellular Carcinoma)

Advanced or Metastatic HCC

United States
Kyowa Kirin, Inc.
Bristol-Myers Squibb

Completed

Study of Mogamulizumab + Nivolumab in Subjects w/Locally Advanced or Metastatic Solid Tumors

Carcinoma | HCC | Cancer | Hepatocellular Carcinoma | Solid Tumor

United States
Daiichi Sankyo, Inc.

Terminated

An Open Study Assessing the Safety and Tolerability of U3-1784

Advanced Solid Tumors | Hepatocellular Cancer (HCC)

United Kingdom
Helio Genomics

Recruiting

Multi-analyte Blood Test Clinical Trial (LIVER-1)

Liver Cirrhosis | HCC | Hepatocellular Carcinoma | Liver Cancer

United States
Ciprian Catana, MD, PhD
National Cancer Institute (NCI)

Recruiting

Multimodal Machine Learning Characterization of Solid Tumors

Glioma | Hepatocellular Carcinoma (HCC) | Prostate Cancer | Adenocarcinoma of Prostate | Renal Cell Carcinoma (RCC) | Radical Prostatectomy

United States
Vicus Therapeutics

Unknown

Study of Sorafenib With or Without VT-122 in Patients With Hepatocellular Carcinoma (HCC)

HCC

United States
SillaJen, Inc.

Completed

Hepatocellular Carcinoma Study Comparing Vaccinia Virus Based Immunotherapy Plus Sorafenib vs Sorafenib Alone (PHOCUS)

Hepatocellular Carcinoma (HCC)

United States, Canada, New Zealand, Australia, China, France, Germany, Hong Kong, Israel, Italy, Korea, Republic of, Portugal, Singapore, Taiwan, Thailand, United Kingdom
National Institutes of Health Clinical Center (CC)

Completed

Integrated Imaging Strategy to Phenotype Progression of Liver Tumors During and After Chemoembolization

HCC | Hepatocellular Carcinoma | Liver Neoplasm | Liver Cancer

United States
Bristol-Myers Squibb

Completed

First Line Hepato Cellular Carcinoma (HCC) (BRISK FL)

Hepato Cellular Carcinoma (HCC)

United States, Argentina, Australia, Belgium, Brazil, Canada, China, Czech Republic, France, Germany, Hong Kong, India, Italy, Japan, Korea, Republic of, Mexico, Poland, Puerto Rico, Russian Federation, South Africa, Spain, Sweden, ... and more
Roswell Park Cancer Institute
National Comprehensive Cancer Network

Completed

Sorafenib Tosylate in Treating Patients With Liver Cancer That Cannot Be Removed by Surgery

Advanced Adult Hepatocellular Carcinoma | Localized Non-Resectable Adult Hepatocellular Carcinoma | Stage IIIA Hepatocellular Carcinoma | Stage IIIB Hepatocellular Carcinoma | Stage IIIC Hepatocellular Carcinoma | Stage IVA Hepatocellular Carcinoma | Stage IVB Hepatocellular Carcinoma | Stage III... and other conditions

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Sorafenib Tosylate and Yttrium Y 90 Glass Microspheres in Treating Patients With Liver Cancer That Cannot Be Removed by Surgery

Unresectable Hepatocellular Carcinoma | Advanced Adult Hepatocellular Carcinoma | Stage IIIB Hepatocellular Carcinoma AJCC v7 | Stage IIIC Hepatocellular Carcinoma AJCC v7 | BCLC Stage C Hepatocellular Carcinoma | Stage IV Hepatocellular Carcinoma AJCC v7 | Stage III Hepatocellular Carcinoma AJCC... and other conditions

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Durvalumab and Tremelimumab After Radioembolization for the Treatment of Unresectable, Locally Advanced Liver Cancer

Unresectable Hepatocellular Carcinoma | Stage III Hepatocellular Carcinoma AJCC v8 | Stage IIIA Hepatocellular Carcinoma AJCC v8 | Stage IV Hepatocellular Carcinoma AJCC v8 | Stage IVA Hepatocellular Carcinoma AJCC v8 | Stage IVB Hepatocellular Carcinoma AJCC v8 | BCLC Stage B Hepatocellular Carcinoma and other conditions

United States
Roswell Park Cancer Institute
Merck Sharp & Dohme LLC

Active, not recruiting

Sorafenib Tosylate and Pembrolizumab in Treating Patients With Advanced or Metastatic Liver Cancer

Advanced Adult Hepatocellular Carcinoma | Child-Pugh Class A | Stage III Hepatocellular Carcinoma | Stage IIIA Hepatocellular Carcinoma | Stage IIIB Hepatocellular Carcinoma | Stage IIIC Hepatocellular Carcinoma | Stage IV Hepatocellular Carcinoma | Stage IVA Hepatocellular Carcinoma | Stage IVB Hepatocellular...

United States
National Cancer Institute (NCI)

Completed

Tremelimumab With Chemoembolization or Ablation for Liver Cancer

Hepatocellular Carcinoma | Biliary Tract Neoplasms | Liver Cancer | Biliary Cancer | Heptocellular Cancer

United States
Edward Kim
Bristol-Myers Squibb; National Cancer Institute (NCI)

Terminated

BMS-986205 and Nivolumab as First or Second Line Therapy in Treating Patients With Liver Cancer

Unresectable Hepatocellular Carcinoma | Stage III Hepatocellular Carcinoma AJCC v8 | Stage IIIA Hepatocellular Carcinoma AJCC v8 | Stage IV Hepatocellular Carcinoma AJCC v8 | Stage IVA Hepatocellular Carcinoma AJCC v8 | Stage IVB Hepatocellular Carcinoma AJCC v8 | Stage IIIB Hepatocellular Carcinoma... and other conditions

United States
Mayo Clinic
National Cancer Institute (NCI)

Recruiting

Futibatinib and Pembrolizumab for Treatment of Advanced or Metastatic FGF19 Positive BCLC Stage A, B, or C Liver Cancer

Advanced Hepatocellular Carcinoma | BCLC Stage B Hepatocellular Carcinoma | BCLC Stage C Hepatocellular Carcinoma | Metastatic Hepatocellular Carcinoma | BCLC Stage A Hepatocellular Carcinoma

United States
Northwestern University
Bristol-Myers Squibb; National Cancer Institute (NCI)

Completed

Nivolumab and Yttrium Y 90 Glass Microspheres in Treating Patients With Advanced Liver Cancer

Stage IIIA Hepatocellular Carcinoma | Stage IIIB Hepatocellular Carcinoma | Stage IIIC Hepatocellular Carcinoma | Stage IVA Hepatocellular Carcinoma | Stage IVB Hepatocellular Carcinoma

United States
OHSU Knight Cancer Institute
Oregon Health and Science University; American Society of Clinical Oncology; Radiological... and other collaborators

Withdrawn

Y-90 Versus SBRT for Inoperable HCC

Hepatocellular Carcinoma | Stage III Hepatocellular Carcinoma AJCC v8 | Stage IIIA Hepatocellular Carcinoma AJCC v8 | Stage IVA Hepatocellular Carcinoma AJCC v8 | Stage IIIB Hepatocellular Carcinoma AJCC v8 | Stage IB Hepatocellular Carcinoma AJCC v8 | Stage II Hepatocellular Carcinoma AJCC v8 | Stage... and other conditions

United States
Jennerex Biotherapeutics

Completed

A Phase 2b Study of Modified Vaccinia Virus to Treat Patients Advanced Liver Cancer Who Failed Sorafenib (TRAVERSE)

HCC | Hepatocellular Carcinoma | Liver Cancer

Korea, Republic of, United States, Hong Kong, Canada, Germany, France, Taiwan
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Radioembolization for HCC Patients With Personalized Yttrium-90 Dosimetry for Curative Intent (RAPY90D)

Unresectable Hepatocellular Carcinoma | Stage III Hepatocellular Carcinoma AJCC v8 | Stage IIIA Hepatocellular Carcinoma AJCC v8 | Stage IV Hepatocellular Carcinoma AJCC v8 | Stage IVA Hepatocellular Carcinoma AJCC v8 | Stage IVB Hepatocellular Carcinoma AJCC v8 | Stage IIIB Hepatocellular Carcinoma...

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Yttrium Y 90 Glass Microspheres in Treating Patients With Unresectable Hepatocellular Carcinoma

Unresectable Hepatocellular Carcinoma | Stage III Hepatocellular Carcinoma AJCC v8 | Stage IIIA Hepatocellular Carcinoma AJCC v8 | Stage IV Hepatocellular Carcinoma AJCC v8 | Stage IVA Hepatocellular Carcinoma AJCC v8 | Stage IVB Hepatocellular Carcinoma AJCC v8 | Stage IIIB Hepatocellular Carcinoma...

United States
Codiak BioSciences

Terminated

A Study of exoASO-STAT6 (CDK-004) in Patients With Advanced Hepatocellular Carcinoma (HCC) and Patients With Liver Metastases From EIther Primary Gastric Cancer or Colorectal Cancer (CRC)

Advanced Hepatocellular Carcinoma (HCC) | Gastric Cancer Metastatic to Liver | Colorectal Cancer Metastatic to Liver

United States

Clinical Trials on Hepatocellular Carcinoma (HCC) in United States

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