Clinical Trials on Hereditary Non-polyposis Colon Cancer in United Kingdom

Total 3809 results

St George's, University of London

Terminated

Intrauterine Levonorgestrel and Observation or Observation Alone in Preventing Atypical Endometrial Hyperplasia and Endometrial Cancer in Women With Hereditary Non-Polyposis Colorectal Cancer or Lynch Syndrome

Endometrial Cancer | Hereditary Non-polyposis Colon Cancer (hmsh2, hmlh1, hpms1, hpms2)

United Kingdom
Ohio State University Comprehensive Cancer Center

Completed

Single Incision Laparoscopic Surgery in Treating Patients With Colorectal Disease

Crohn Disease | Familial Adenomatous Polyposis | Stage IIIA Colon Cancer | Stage IIIB Colon Cancer | Stage IIIC Colon Cancer | Recurrent Colon Cancer | Stage I Colon Cancer | Stage IIA Colon Cancer | Stage IIB Colon Cancer | Stage IIC Colon Cancer | Adenomatous Polyp | Hereditary Intestinal Polyposis Syndrome

United States
Fox Chase Cancer Center
National Cancer Institute (NCI)

Completed

Educational CD-ROM Compared With Standard Informed Consent for Patients With Colorectal Cancer or a Family History of Colorectal Cancer

Colorectal Cancer | Hereditary Non-polyposis Colon Cancer

United States
Vanderbilt University Medical Center
National Cancer Institute (NCI)

Completed

Collecting Information From Patients and Family Members With Hereditary Colorectal Cancer Syndromes or Who Are at High Risk of Developing Colorectal Cancer

Colorectal Cancer | Precancerous Condition | Hereditary Non-polyposis Colon Cancer

United States
Johns Hopkins University
National Human Genome Research Institute (NHGRI)

Completed

Genetic Risk: Whether, When, and How to Tell Adolescents

Huntington Disease | Hereditary Cancer | Hereditary Breast and Ovarian Cancer | Hereditary Non-polyposis Colon Cancer | Hereditary Non-Polyposis Colorectal Cancer Syndrome

United States
London North West Healthcare NHS Trust

Completed

Magnification Narrow Band Imaging Colonoscopy for Hereditary Non-Polyposis Colorectal Cancer Surveillance

Colorectal Neoplasms, Hereditary Nonpolyposis

United Kingdom
Royal Marsden NHS Foundation Trust

Recruiting

Inherited Cancer Early Diagnosis (ICED) Study (ICED)

Lynch Syndrome | Familial Adenomatous Polyposis | Hereditary Diffuse Gastric Cancer | Peutz-Jeghers Syndrome | Cowden Syndrome | Li Fraumeni Syndrome | MutYH-associated Polyposis | SMAD4 Gene Mutation

United Kingdom
London North West Healthcare NHS Trust

Unknown

Adenoma Detection Rate:NBI, AFI, Chromoscopic or Standard Endoscopy

Familial Adenomatous Polyposis

United Kingdom
S.L.A. Pharma AG

Completed

Chemoprevention Trial in Familial Adenomatous Polyposis (FAP) Coli Using EPA

FAP | Familial Adenomatous Polyposis Coli

United Kingdom
National Cancer Institute (NCI)

Completed

Phase I-II Multiple-Dose Safety and Efficacy Study of a Selective Inhibitor of Cyclooxygenase - 2 (SC-58635) in Hereditary Non-Polyposis Colorectal Cancer (HNPCC) Patients and Carriers

Colorectal Neoplasm | Hereditary Nonpolyposis

United States
University of North Carolina, Chapel Hill
North Carolina Translational and Clinical Sciences Institute

Not yet recruiting

PeLear CCC: Proyecto Latino Contra Cancer Colorectal (PeLear CCC)

Colorectal Cancer | Rectal Cancer | Rectal Neoplasms | Colon Cancer | Colon Adenocarcinoma | Colon Rectal Cancer | Hereditary Nonpolyposis Colon Cancer

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Survivorship Care Planning in Patients With Colorectal or Non-Small Cell Lung Cancer

Stage IIA Rectal Cancer | Stage IIB Rectal Cancer | Stage IIC Rectal Cancer | Stage IIIA Rectal Cancer | Stage IIIB Rectal Cancer | Stage IIIC Rectal Cancer | Stage IIIA Non-small Cell Lung Cancer | Stage IIIB Non-small Cell Lung Cancer | Stage IIIA Colon Cancer | Stage IIIB Colon Cancer | Stage IIIC Colon... and other conditions

United States
Royal Marsden NHS Foundation Trust
Pelican Cancer Foundation

Completed

Surgical Anatomy and 'Waisting' of the sIgmoid SpEcimen (WISE)

Sigmoid, Sigmoid Colon, Neoplasm, Cancer

United Kingdom
Stanford University

Terminated

Clinical and Pathologic Studies of Patients Undergoing Treatment With EGFR Inhibitors

Head and Neck Cancer | Colorectal Neoplasms | Lung Cancer | Colon Cancer | Colonic Neoplasms | Head and Neck Cancers | Anal, Colon, and Rectal Cancers | Colon/Rectal Cancer | Colon/Rectal Cancer Colon Cancer | Colon/Rectal Cancer Rectal Cancer | Colon/Rectal Cancer Anal Cancer | Head and Neck Cancers Lip | Head... and other conditions

United States
Fox Chase Cancer Center

Completed

Adherence to Survivorship Care Guidelines in Health Care Providers for Non-Small Cell Lung Cancer and Colorectal Cancer Survivor Care

Mucinous Adenocarcinoma of the Rectum | Signet Ring Adenocarcinoma of the Rectum | Stage IIA Rectal Cancer | Stage IIB Rectal Cancer | Stage IIC Rectal Cancer | Stage IIIA Rectal Cancer | Stage IIIB Rectal Cancer | Stage IIIC Rectal Cancer | Stage IIIA Non-small Cell Lung Cancer | Stage IIIB Non-small... and other conditions

United States
Royal Marsden NHS Foundation Trust
Merck KGaA, Darmstadt, Germany; University of Oxford; University of Surrey

Terminated

Avelumab Plus 5-FU Based Chemotherapy as Adjuvant Treatment for Stage 3 MSI-High or POLE Mutant Colon Cancer (POLEM)

Microsatellite Instability | Stage III Colon Cancer | POLE Exonuclease Mutant Colon Cancer

United Kingdom
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Celecoxib in Preventing Colorectal Cancer in Young Patients With a Genetic Predisposition for Familial Adenomatous Polyposis

Colorectal Cancer | Precancerous Condition

United States
University of Pittsburgh

Completed

Hereditary Colorectal and Associated Tumor Registry Study

Lynch Syndrome | Hereditary Diffuse Gastric Cancer | FAP | Peutz-Jeghers Syndrome | Juvenile Polyposis Syndrome

United States
University of Pennsylvania
Epigenomics, Inc

Completed

Preliminary Evaluation of Septin9 in Patients With Hereditary Colon Cancer Syndromes (Septin9)

Colorectal Cancer | Lynch Syndrome | Familial Adenomatous Polyposis | Map Syndrome | Hnpcc

United States
Corporal Michael J. Crescenz VA Medical Center

Terminated

Non-Invasive Prediction of Colorectal Neoplasia (NIPCON)

Colorectal Cancer | Colonic Polyps | Polyposis Coli

United States
National Cancer Institute (NCI)

Completed

Celecoxib With or Without Eflornithine in Preventing Colorectal Cancer in Patients With Familial Adenomatous Polyposis

Colorectal Cancer | Familial Adenomatous Polyposis

United States
National Human Genome Research Institute (NHGRI)

Completed

Psychosocial Aspects of Genetic Testing for Hereditary Nonpolyposis Colon Cancer

HNPCC | Hereditary Nonpolyposis Colon Cancer

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Multimedia Intervention in Patients With Familial Adenomatous Polyposis (FAP)

Colorectal Cancer | Familial Adenomatous Polyposis

United States
Fog Pharmaceuticals, Inc.

Recruiting

FOG-001 in Locally Advanced or Metastatic Solid Tumors

Cancer | Gastric Cancer | Colorectal Cancer | Solid Tumor | Metastatic Cancer | Adenomatous Polyposis Coli | Non-small Cell Lung Cancer | Non-small Cell Lung Cancer Metastatic | Non-small Cell Carcinoma | Locally Advanced Solid Tumor | Non-small Cell Lung Cancer Stage IIIB | Gastroesophageal-junction Cancer | Non-Small... and other conditions

United States
M.D. Anderson Cancer Center

Completed

Non-Surgical Management of Attenuated and Deleterious (Classical) Familial Adenomatous Polyposis: A Long-term Surveillance Program

Attenuated Familial Adenomatous Polyposis | Deleterious Familial Adenomatous Polyposis

United States
Cancer Prevention Pharmaceuticals, Inc.

Completed

Trial of Eflornithine Plus Sulindac in Patients With Familial Adenomatous Polyposis (FAP)

Familial Adenomatous Polyposis

United States, Belgium, Germany, Canada, Netherlands, Spain, United Kingdom
London North West Healthcare NHS Trust

Active, not recruiting

Body Composition Manipulation in CoLorectal cancEr (BiCyCLE): Neuromuscular Electrical Stimulation (NMES) (BiCyCLE-NMES)

Colorectal Cancer | Rectal Cancer | Sarcopenia | Advanced Cancer | Colon Cancer | Colo-rectal Cancer | Sarcopenic Obesity | Recurrent Rectal Cancer

United Kingdom
Vanderbilt University Medical Center

Enrolling by invitation

Visualization of the Papilla Through Use of the NuView Device in Patients With FAP (NuView)

Familial Adenomatous Polyposis

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Molecular Targeting of 15-Lipoxygenase-1 (15-LOX-1) for Apoptosis Induction in Human Colorectal Cancers

Familial Adenomatous Polyposis

United States
National Cancer Institute (NCI)

Completed

Review of Post-Study Clinical Endoscopy Reports in Follow Up to MAY2016-07-01

Familial Adenomatous Polyposis

United States
Stanford University
Caring for Carcinoid Foundation; GI Cancer Research Gift Fund

Withdrawn

Collection of Biospecimen & Clinical Information in Patients w/ Gastrointestinal Cancers

Gastrointestinal Neoplasms | Pancreatic Cancer | Anal Cancer | Colon/Rectal Cancer | Hepatobiliary Cancers | Gastric (Stomach) Cancer | Gynecologic Cancers | Gastro-Esophageal(GE) Junction Cancer | Gynecologic Cancers Cervical Cancer | Gastrointenstinal Stromal Tumor (GIST) | Colon/Rectal Cancer Colon Cancer and other conditions

United States
W.L.Gore & Associates

Terminated

Bioabsorbable Staple Line Reinforcement in Colorectal,Coloanal and Ileoanal Anastomoses

Rectal Cancer | Ulcerative Colitis | Familial Adenomatous Polyposis | Diverticulitis

United States
London North West Healthcare NHS Trust

Completed

Detection in Tandem Endocuff Cap Trial (DETECT)

Colonic Neoplasms | Colo-rectal Cancer | Colon Adenoma | Adenomas Serrated

United Kingdom
National Cancer Institute (NCI)

Recruiting

Hereditary Gastric Cancer Syndromes: An Integrated Genomic and Clinicopathologic Study of the Predisposition to Gastric Cancer

Stomach Neoplasms | Stomach Cancer | Gastric Adenocarcinoma and Proximal Polyposis of the Stomach (GAPPS) | Hereditary Diffuse Gastric Cancer (HDGC) | Familial Diffuse Gastric Cancer

United States
Recursion Pharmaceuticals Inc.

Recruiting

Evaluate REC-4881 in Patients With FAP (TUPELO)

Familial Adenomatous Polyposis

United States
Integra LifeSciences Corporation

Terminated

An Evaluation of SprayShield in Reducing Post-Operative Adhesion Formation Following Major Open Abdominal Surgery

Ulcerative Colitis | Familial Polyposis

United States
Stanford University

Completed

Evaluation of EverLift in the Performance of Polypectomy for Polyps 4-9mm

Polyp of Colon | Colo-rectal Cancer | Adenomatous Polyp of Colon

United States
National Cancer Institute (NCI)
NSABP Foundation Inc

Completed

Fluorouracil, Leucovorin, and Oxaliplatin With or Without Bevacizumab in Treating Patients Who Have Undergone Surgery for Stage II or Stage III Colon Cancer

Colon Adenocarcinoma | Stage IIIA Colon Cancer AJCC v7 | Stage IIIB Colon Cancer AJCC v7 | Stage IIIC Colon Cancer AJCC v7 | Stage IIA Colon Cancer AJCC v7 | Stage IIB Colon Cancer AJCC v7 | Stage IIC Colon Cancer AJCC v7

United States
Pfizer

Terminated

Observational Familial Adenomatous Polyposis Registry Study In Patients Receiving Celecoxib Compared to Control Patients

Familial Adenomatous Polyposis (FAP)

United States, Spain, Canada, Denmark
Case Comprehensive Cancer Center

Completed

PET-MRI in Diagnosing Patients With Colon or Rectal Cancer

Stage IIA Rectal Cancer | Stage IIB Rectal Cancer | Stage IIC Rectal Cancer | Stage IIIA Rectal Cancer | Stage IIIB Rectal Cancer | Stage IIIC Rectal Cancer | Stage IIIA Colon Cancer | Stage IIIB Colon Cancer | Stage IIIC Colon Cancer | Recurrent Colon Cancer | Recurrent Rectal Cancer | Stage IVA Colon Cancer | Stage IVA Rectal Cancer and other conditions

United States
University of Leeds
National Cancer Institute (NCI); Massachusetts General Hospital; Massachusetts... and other collaborators

Recruiting

Prebiotic Effect of Eicosapentaenoic Acid Treatment for Colorectal Cancer Liver Metastases

Colon Cancer Liver Metastasis

United Kingdom
Johns Hopkins University
Pentax Medical

Active, not recruiting

CryoBalloon Ablation for Treatment of Duodenal Adenomas (C2D2)

Familial Adenomatous Polyposis | Duodenal Adenomas

United States
National Cancer Institute (NCI)

Active, not recruiting

Oxaliplatin, Leucovorin Calcium, and Fluorouracil With or Without Bevacizumab in Treating Patients Who Have Undergone Surgery for Stage II Colon Cancer

Lynch Syndrome | Colon Mucinous Adenocarcinoma | Colon Signet Ring Cell Adenocarcinoma | Stage IIA Colon Cancer AJCC v7 | Stage IIB Colon Cancer AJCC v7 | Stage IIC Colon Cancer AJCC v7

United States, Canada, Puerto Rico, Peru, South Africa
University Hospital Southampton NHS Foundation...
Royal Bournemouth and Christchurch Hospitals NHS Foundation Trust

Unknown

Exercise Intervention During Chemotherapy in Advanced Lung Cancer Patients (EMBRACE)

Non Small Cell Lung Cancer | Non Small Cell Lung Cancer Stage IIIB | Non Small Cell Lung Cancer Metastatic

United Kingdom
MeiraGTx UK II Ltd

Completed

Natural History Study for Achromatopsia

Achromatopsia

United Kingdom
Vanderbilt-Ingram Cancer Center
National Cancer Institute (NCI)

Completed

Programs to Support You During Chemotherapy (Pro-You) (Pro-You)

Fatigue | Depressive Symptoms | Stage IIA Rectal Cancer | Stage IIB Rectal Cancer | Stage IIC Rectal Cancer | Stage IIIA Rectal Cancer | Stage IIIB Rectal Cancer | Stage IIIC Rectal Cancer | Psychosocial Effects of Cancer and Its Treatment | Stage IIIA Colon Cancer | Stage IIIB Colon Cancer | Stage IIIC Colon... and other conditions

United States
Glasgow Royal Infirmary

Recruiting

Advanced Pelvic Surgical Oncology Database - Prospective Observational Study

Gynecologic Cancer | Rectal Cancer | Pelvic Cancer | Colon Cancer

United Kingdom
Pfizer's Upjohn has merged with Mylan to form Viatris...

Terminated

Trial In Pediatric Patients With Familial Adenomatous Polyposis (FAP) (CHIP)

Adenomatous Polyposis Coli

Italy, United States, Belgium, Spain, Puerto Rico, Sweden, Israel, Czechia, Hong Kong, Hungary, Slovakia, South Africa, Ukraine, United Kingdom
University of Utah
National Cancer Institute (NCI)

Completed

A Clinical Trial of COX and EGFR Inhibition in Familial Polyposis Patients (FAPEST)

Adenomatous Polyposis Coli

United States
National Cancer Institute (NCI)

Recruiting

Testing Obeticholic Acid for Familial Adenomatous Polyposis

Familial Adenomatous Polyposis | Colorectal Carcinoma | Attenuated Familial Adenomatous Polyposis | Duodenal Carcinoma

United States, Puerto Rico

Clinical Trials on Hereditary Non-polyposis Colon Cancer in United Kingdom

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