Clinical Trials on Hereditary Complement Deficiency Diseases

Total 11110 results

Erasmus Medical Center

Completed

Dutch Acute HCV in HIV Study (DAHHS-2): Grazoprevir/Elbasvir for Acute HCV (DAHHS-2)

Hepatitis C | Human Immunodeficiency Virus | Acute Hepatitis C

Netherlands, Belgium
Baylor College of Medicine
The Methodist Hospital Research Institute; Center for Cell and Gene Therapy...

Terminated

Antibody Conditioning Regimen For Allogeneic Donor Stem Cell Transplantation Of Patients With Fanconi Anemia (Mafia)

Fanconi Anemia | Severe Aplastic Anemia

United States
Valme University Hospital
Hospital Universitario de Canarias; Hospital Universitario Virgen Macarena; Hospital... and other collaborators

Unknown

Real-life Security and Efficacy of DAA-based Therapy in HCV/HIV-Coinfected Patients

Hepatitis C, Chronic | Human Immunodeficiency Virus

Spain
Alkermes, Inc.

Completed

The Safety and Effectiveness of RMP-7 Plus Amphotericin B in Patients With HIV and Cryptococcal Meningitis

HIV Infections | Meningitis, Cryptococcal

United States
ViiV Healthcare
GlaxoSmithKline

Completed

Open-label Study of Dolutegravir (DTG) or Efavirenz (EFV) for Human Immunodeficiency Virus (HIV) - Tuberculosis (TB) Co-infection

HIV Infections | Infection, Human Immunodeficiency Virus

Mexico, Peru, Thailand, South Africa, Russian Federation, Argentina, Brazil
Hoffmann-La Roche

Completed

Efficacy and Safety of Peg-Interferon Alpha-2a Plus Ribavirin in Genotype 1 Chronic Hepatitis C Participants Co-Infected With Human Immunodeficiency Virus

Hepatitis C, Chronic

Brazil
Pfizer
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Comparison of Fluconazole and Amphotericin B in the Treatment of Brain Infections in Patients With AIDS

HIV Infections | Meningitis, Cryptococcal

United States
Pfizer

Completed

A Study of Fluconazole in the Treatment of Cryptococcal Meningitis in Patients With AIDS

HIV Infections | Meningitis, Cryptococcal

United States
University of Washington
Kenya Medical Research Institute

Completed

Discontinuation of Trimethoprim-sulfamethoxazole Prophylaxis in Adults on Antiretroviral Therapy in Kenya

HIV Infections | Acquired Immunodeficiency Syndrome | Immune System Diseases | Pneumonia | Disease Progression | Diarrhea | Parasitic Diseases | Malaria | Infectious Disorder of Immune System

Kenya
Kangbuk Samsung Hospital
Hanyang University; Kyunghee University Medical Center

Not yet recruiting

Gut Microbiome in People Living With HIV and HBV

Chronic Hepatitis b | Human Immunodeficiency Virus | Gut Microbiome
ViiV Healthcare
GlaxoSmithKline

Completed

HIV Treatment and CVD Events

HIV Infection | Cardiovascular Disease | Acute Myocardial Infarction | Infection, Human Immunodeficiency Virus
University of Pennsylvania
National Institute on Drug Abuse (NIDA)

Completed

Effect of Galantamine on Inflammation and Cognition (CHI)

HIV Associated Cognitive Motor Complex

United States
Rocket Pharmaceuticals Inc.

Unknown

A Clinical Trial to Evaluate the Safety of RP-L102 in Pediatric Subjects With Fanconi Anemia Subtype A

Fanconi Anemia Complementation Group A

United States
Rocket Pharmaceuticals Inc.

Enrolling by invitation

Long-Term Follow-up of Subjects With Fanconi Anaemia Subtype A Treated With ex Vivo Gene Therapy

Fanconi Anemia | Fanconi Anemia Complementation Group A

Spain
Holdsworth House Medical Practice

Completed

Safety and Efficacy of Famciclovir in HIV1 Positive Adults With Recurrent Genital Herpes

HIV Positive | Herpes Simplex, Genital
National Institute of Allergy and Infectious Diseases...
Jacobus Pharmaceutical

Completed

Comparison of Two Dosage Regimens of Oral Dapsone for Prophylaxis of Pneumocystis Carinii Pneumonia in Pediatric HIV Infection

HIV Infections | Pneumonia, Pneumocystis Carinii

United States, Puerto Rico
Assistance Publique - Hôpitaux de Paris

Completed

Polyacrylamide Hydrogel Injection in HIV-related Lipoatrophy (LIPOPHILL)

HIV Infection | Antiretroviral Side Effects | Lipodystrophy Syndrome Related to HIV Infection

France
University of Witwatersrand, South Africa

Completed

Validation of Implementation of Cervical Dysplasia Treatment Modalities in HIV-Seropositive Women (VICAR2)

Cervical Intraepithelial Neoplasia

South Africa
National Cancer Institute (NCI)

Completed

Vandetanib to Treat Children and Adolescents With Medullary Thyroid Cancer

Multiple Endocrine Neoplasia Type 2A | Multiple Endocrine Neoplasia Type 2B | Medullary Thyroid Carcinoma

United States
Gilead Sciences

Completed

Fanconi Syndrome Due to ARVs in HIV-Infected Persons

HIV Infections | Renal Impairment | Fanconi Syndrome | Kidney Disease

Canada, United States
University of Maryland, College Park
National Institute on Drug Abuse (NIDA); University of Miami; Weill Medical College... and other collaborators

Recruiting

Project Khanya: Peer-Delivered Intervention to Improve HIV Medication Adherence and Substance Use in South Africa

Alcohol-Related Disorders | Substance Use | Drug Use | Human Immunodeficiency Virus

South Africa
Brown University
National Institute on Drug Abuse (NIDA); University of California, San Diego; Beth Israel Deaconess Medical Center and other collaborators

Recruiting

Pre-exposure Prophylaxis (PrEP) for Health (PrEP)

Substance Dependence | HIV (Human Immunodeficiency Virus)

United States
ImmunityBio, Inc.

Completed

A Study to Investigate ALDOXORUBICIN in HIV-infected Subjects With Kaposi's Sarcoma

Kaposi's Sarcoma | AIDS | HIV Positive

United States
Diurnal Limited
National Institutes of Health Clinical Center (CC)

Completed

Comparison of Two Forms of Hydrocortisone in Patients With Congenital Adrenal Hyperplasia

Adrenogenital Syndrome | Congenital Adrenal Hyperplasia | 21-Hydroxylase Deficiency

United States
University of Rome Tor Vergata

Completed

DIAGNOSIS of PULMONARY TUBERCULOSIS Through HUMAN BREATH (TBENOSE) (TBENOSE)

HIV Seropositivity | Tuberculosis, Pulmonary

Cameroon
University of Witwatersrand, South Africa

Unknown

A Comparison of Immediate Treatment of CIN1 With Cryotherapy and 12 Month Cytology Follow up in HIV Seropositive Women

Cervical Dysplasia

South Africa
Ferring Pharmaceuticals

Terminated

Evaluation of the Adherence and the Patient Acceptability of Zomacton® Treatment With the Zomajet® Vision X Device (ZOMAXEPT)

Growth Hormone Deficiency | Turner's Syndrome

France
French National Agency for Research on AIDS and...
Hoffmann-La Roche

Completed

Efficacy of Pegylated Interferon on Liver Fibrosis in Co-infected Patient With HIV and Hepatitis C

HIV Infections | Hepatitis C, Chronic

France
University of Pittsburgh

Completed

Genetic and Environmental Determinants That Control Metabolism in Pulmonary Hypertension

Pulmonary Hypertension | Friedreich Ataxia | Iron-sulfur Cluster Deficiency

United States
Montefiore Medical Center
National Cancer Institute (NCI); University of Rwanda; Rwanda Military Hospital

Recruiting

HPV Vaccine Effectiveness Study in Rwandan Women Living With HIV

Cervical Cancer | Human Immunodeficiency Virus | HPV-Related Carcinoma | Human Papilloma Virus

Rwanda
Prism Health North Texas
Merck Sharp & Dohme LLC

Withdrawn

Doravirine and Weight Gain in Antiretroviral Naive (DAWN)

Obesity | Metabolic Syndrome | Body Weight Changes | Human Immunodeficiency Virus | Fasting | Minority Health | ART | BMD

United States
Johns Hopkins University

Completed

Nurse Case Management to Improve Hepatitis C Care in HIV Co-infection (Care2Cure)

Hepatitis C, Chronic | HIV

United States
University Hospital, Bordeaux

Completed

Sexual Hepatitis C in HIV Positive Men Who Have Sex With Men (MSM) in Bordeaux (HEPCSEX)

Human Immunodeficiency Virus (HIV) | Hepatitis c

France
New York City Health and Hospitals Corporation

Completed

Integrating HIV and Hepatitis C Screening in an Urban Emergency Department

Hepatitis C | HIV/AIDS | Hiv | HCV Coinfection | HIV/AIDS and Infections

United States
Duke University

Terminated

Accuracy of Portable Colposcopy and HPV Genotypes Among HIV+ Women

Cervical Cancer | Human Immunodeficiency Virus | Human Papillomavirus

Haiti
G & W Laboratories Inc.
Alquest; SMART Biotech Ltd

Completed

Comparison of Plasma & SMARTplasma for Human Immunodeficiency Virus (HIV) and Hepatitis C Virus (HCV) Antibody Testing

Hepatitis C | Human Immunodeficiency Virus Infection

United States
Recursion Pharmaceuticals Inc.

Recruiting

Efficacy and Safety of REC-2282 in Patients With Progressive Neurofibromatosis Type 2 (NF2) Mutated Meningiomas (POPLAR-NF2)

Neurofibromatosis Type 2

United States
Jonsson Comprehensive Cancer Center
Novartis Pharmaceuticals

Terminated

Study of RAD001 for Treatment of NF2-related Vestibular Schwannoma

Neuroma, Acoustic | Neurofibromatosis Type 2

United States
Massachusetts General Hospital
United States Department of Defense; AstraZeneca

Completed

AZD2014 In NF2 Patients With Progressive or Symptomatic Meningiomas

Meningioma | Neurofibromatosis 2

United States
NYU Langone Health

Completed

Study of Axitinib in Patients With Neurofibromatosis Type 2 and Progressive Vestibular Schwannomas

Neurofibromatosis Type 2 | Vestibular Schwannomas

United States
Li Peng
Betta Pharmaceuticals Co., Ltd.

Completed

Icotinib Study for Patients With Neurofibromatosis Type 2 (NF2) and NF2-Related Tumors (Icotinib)

Neurofibromatosis Type 2 | Vestibular Schwannoma

China
National Cancer Institute (NCI)

Completed

Bevacizumab for Symptomatic Vestibular Schwannoma in Neurofibromatosis Type 2 (NF2)

Neurofibromatosis Type 2 | Vestibular Schwannoma

United States
Beijing Tiantan Hospital
Shandong Simcere-Medgenn Bio-pharmaceutical Co., Ltd

Completed

Endostatin Study for Patients With Neurofibromatosis Type 2 (NF2) and NF2-Related Tumors (Endostatin)

Neurofibromatosis Type 2 | Vestibular Schwannoma

China
Shenzhen Second People's Hospital
Guangzhou Women and Children's Medical Center; Shenzhen University

Recruiting

Autologous Hematopoietic Stem Cell Gene Therapy for Metachromatic Leukodystrophy and Adrenoleukodystrophy

Adrenoleukodystrophy | Metachromatic Leukodystrophy

China
Travere Therapeutics, Inc.

Recruiting

Study of Sparsentan Treatment in Pediatrics With Proteinuric Glomerular Diseases (EPPIK)

Focal Segmental Glomerulosclerosis | Immunoglobulin A Nephropathy | Minimal Change Disease | Alport Syndrome | IgA Vasculitis

United States, Italy, Netherlands, Poland, Spain, United Kingdom, Germany, Sweden
University of California, San Francisco
National Institute of Allergy and Infectious Diseases (NIAID); University Hospital... and other collaborators

Not yet recruiting

Pragmatic Use of Next-generation Sequencing for Management of Drug-resistant Tuberculosis (TSELiOT)

Drug-resistant Tuberculosis | Cost-Benefit Analysis | HIV Coinfection

South Africa
Yale University
National Institute on Drug Abuse (NIDA); Universiti Sains Malaysia

Recruiting

Implementation of STTR Strategies Among People Who Inject Drugs in Malaysia

HIV Seropositivity | Opioid-use Disorder

Malaysia
Kirby Institute
ViiV Healthcare; University of Witwatersrand, South Africa; University of Liverpool and other collaborators

Completed

COHIVE: Coronavirus (COVID-19) Outcomes in HIV Evaluation in Resource Limited Settings

Coronavirus Infection | HIV-infection/Aids

Uganda, Cameroon, Argentina, Brazil, India, Malaysia, Nigeria, South Africa, Thailand, Zimbabwe
University of California, San Francisco
California HIV/AIDS Research Program

Completed

Treatment of Acute Hepatitis C Virus in HIV Co-Infection

HIV Infections | Hepatitis C | Human Immunodeficiency Virus

United States
Sun Yat-sen University

Recruiting

Cadonilimab for PD-1/PD-L1 Blockade-refractory, MSI-H/dMMR, Advanced Colorectal Cancer

Colorectal Cancer Stage IV | Mismatch Repair-deficient (dMMR) | Microsatellite Instability-high (MSI-H)

China

Clinical Trials on Hereditary Complement Deficiency Diseases

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Bahrain

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations