Clinical Trials on Hereditary Paraganglioma-pheochromocytoma

Total 2754 results

University Hospital, Angers

Unknown

Trial of Cyclosporine in the Acute Phase of Leber Hereditary Optic Neuropathy (CICLO-NOHL)

Leber Hereditary Optic Neuropathy

France
HAE Global Registry Foundation

Recruiting

Global Registry to Gather Data on Natural History of Patients With Hereditary Angioedema Type I and II (HGR)

Hereditary Angioedema Type I and II

Italy
KalVista Pharmaceuticals, Ltd.

Completed

A Phase II, Cross-over Clinical Trial Evaluating the Efficacy and Safety of KVD900 in the On-demand Treatment of Angioedema Attacks in Adult Subjects With Hereditary Angioedema Type I or II

Hereditary Angioedema

United States, Austria, Czechia, Germany, Hungary, Italy, Netherlands, North Macedonia, Poland, United Kingdom
Bin Li
Huazhong University of Science and Technology

Completed

Safety and Efficacy Study of rAAV2-ND4 Treatment of Leber Hereditary Optic Neuropathy (LHON) (rAAV2-ND4)

Leber Hereditary Optic Neuropathy

China
Prothya Biosolutions

Completed

Kinetics, Efficacy and Safety of C1-Esteraseremmer-N

Hereditary Angioedema Type I | Angioneurotic Edema

Netherlands
Hospital de Olhos Sadalla Amin Ghanem

Completed

Fundus Changes in the Microphthalmy Eyes

Eye Diseases, Hereditary
Netherlands Institute for Innovative Ocular Surgery
Amnitrans Eyebank Rotterdam

Completed

Descemet Membrane Endothelial Keratoplasty (DMEK) (DMEK)

Corneal Dystrophies, Hereditary

Netherlands
University Hospital, Clermont-Ferrand

Recruiting

Genomics of Fibrin Clot Structure in Patients With Constitutional Dysfibrinogenemia (GENDYSFIB)

Hereditary Dysfibrinogenemia

France
Wolfson Medical Center

Unknown

Hemolysis in Patients With Hereditary Spherocytosis (HS)

Hemolysis | Hereditary

Israel
Price Vision Group

Terminated

Trial of Netarsudil for Acceleration of Corneal Endothelial Restoration

Fuchs' Endothelial Dystrophy

United States
Singapore National Eye Centre

Unknown

Evaluation of the Efficacy of Descemet Membrane Transplantation for the Treatment of Fuchs' Endothelial Dystrophy

Fuchs' Endothelial Dystrophy

Singapore
Centre Hospitalier Régional Metz-Thionville

Completed

Comparative Results After DSAEK, UT-DSAEK and DMEK for Fuchs Endothelial Corneal Dystophy (DEMOGRAFT)

Corneal Dystrophy

France
Santhera Pharmaceuticals

Withdrawn

Study With Idebenone in Patients With Chronic Vision Loss Due to Leber's Hereditary Optic Neuropathy (LHON)

Leber's Hereditary Optic Neuropathy
Perspective Therapeutics

Recruiting

Targeted Alpha-Particle Therapy for Advanced SSTR2 Positive Neuroendocrine Tumors (212-Pb-VMT)

Neuroendocrine Tumors | Pheochromocytoma | Carcinoid Tumor | Paraganglioma | Neuroendocrine Tumor of the Lung | Neuroendocrine Carcinoma Metastatic | Neuroendocrine Tumor of Pancreas | Neuroendocrine Tumor Carcinoid | Carcinoid Tumor of GI System

United States
University of Basel
Kantonsspital Aarau

Completed

Prevention of Conversion in Posterior Retroperitoneal Adrenalectomy by Measuring Preoperative Anatomical Conditions

Pheochromocytoma | Adrenal Tumor | Adrenal Mass | Adrenal Hyperplasia | Adrenal Metastases | Conn Adenoma

Switzerland
Massachusetts General Hospital

Completed

L-Serine Supplementation in Hereditary Sensory Neuropathy Type 1

Hereditary Sensory and Autonomic Neuropathy Type I

United States
Massachusetts Eye and Ear Infirmary

Completed

Netarsudil Use After Descemtorhexis Without Endothelial Keratoplasty

Fuchs' Endothelial Dystrophy

United States
University of Aarhus

Active, not recruiting

A Comparison of Visual Functions and Side-effects After DSAEK or DMEK for Fuchs' Endothelial Dystrophy

Fuchs' Endothelial Dystrophy

Denmark
Maastricht University Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development

Completed

DMEK Versus DSAEK Study (DMEK)

Fuchs' Endothelial Dystrophy

Netherlands
Oregon Health and Science University

Terminated

OCT-guided DSAEK Graft Shaping and Smoothing (DSAEK)

Fuchs' Endothelial Dystrophy

United States
Medical University of Vienna

Recruiting

Correlation Between In-vivo Anatomy of Corneal Dystrophies as Assessed by High- Resolution Optical Coherence Tomography (OCT) Measurement and Histological Examination

Corneal Dystrophy

Austria
Argo Sante
GenSight Biologics

Completed

Evaluation of Impact of Disease and Visual Disability on Quality of Life and Loss of Independence of Patients Living in France With Leber's Hereditary Optic Neuropathy (LHON) Through Qualitative and Quantitative Data Collection

Leber's Hereditary Optic Neuropathy (LHON)

France
Santhera Pharmaceuticals

No longer available

Expanded Access Program for Idebenone in Patients With Leber's Hereditary Optic Neuropathy Who Completed the LEROS Study (US EAP LHON)

Leber's Hereditary Optic Neuropathy
Stealth BioTherapeutics Inc.

Completed

A Study Investigating the Safety, Tolerability, and Efficacy of Elamipretide Topical Ophthalmic Solution for Treatment of Leber's Hereditary Optic Neuropathy

Leber's Hereditary Optic Neuropathy

United States
Universitaire Ziekenhuizen KU Leuven
Fund for Scientific Research, Flanders, Belgium; Funds for Research in Ophthalmology... and other collaborators

Completed

The Molecular Pathogenesis of Late-onset Fuchs' Endothelial Corneal Dystrophy

Fuchs' Endothelial Dystrophy

Belgium
Institut National de la Santé Et de la Recherche...

Unknown

Immunome Project Consortium for Autoinflammatory Disorders (ImmunAID)

Autoinflammatory Diseases, Hereditary
National Eye Institute (NEI)

Completed

Studies in Families With Corneal Dystrophy or Other Inherited Corneal Diseases

Corneal Dystrophies, Hereditary | Corneal Disease

United States, China, Italy
Johns Hopkins University

Recruiting

Neodymium-doped Yttrium Aluminum Garnet (Nd:YAG) Laser Treatment for Granular Corneal Dystrophy

Granular Dystrophy, Corneal

United States
Weill Medical College of Cornell University

Recruiting

Chatbot to Maximize Hereditary Cancer Genetic Risk Assessment

Gynecologic Cancer | Hereditary Cancer Syndrome

United States
University Eye Hospital, Freiburg

Completed

Supine Positioning for Graft Attachment After Descemet Membrane Endothelial Keratoplasty (SUPER-DMEK)

Fuchs' Endothelial Dystrophy

Germany
Takeda

Recruiting

A Study to Review the Treatment and Outcomes of Teenagers and Adults With Non-histaminergic Angioedema With Normal C1 Inhibitor in Canada (PROSPECT)

Angioedema | Hereditary Angioedema (HAE)

Canada
Takeda

Recruiting

A Study in Adults With Hereditary Angioedema (HAE) Who Currently Receive Icatibant at Home

Hereditary Angioedema (HAE)

United Kingdom
Shire
Takeda Development Center Americas, Inc.

No longer available

Expanded Access for the Prevention of Acute Attacks of 1) Hereditary Angioedema (HAE) in Children and 2) Non-histaminergic Angioedema With Normal C1-Inhibitor (C1-INH) in Teenagers and Adults

Angioedema | Hereditary Angioedema (HAE)

United States, Canada, Germany, Hungary, Spain
Shire

Completed

Efficacy and Safety of Lanadelumab (SHP643) in Japanese Participants With Hereditary Angioedema (HAE)

Hereditary Angioedema (HAE)

Japan
Shire

Completed

A Pharmacokinetic, Tolerability and Safety Study of Icatibant in Children and Adolescents With Hereditary Angioedema

Hereditary Angioedema (HAE)

United States, Canada, Australia, Austria, Colombia, Germany, Hungary, Israel, Italy, Spain
Shire

Completed

Safety and Efficacy Study of Repeated Doses of DX-88 (Ecallantide) to Treat Attacks of Hereditary Angioedema (HAE)

Hereditary Angioedema (HAE)

United States, Canada, Jordan
Shire

Completed

Observational Safety Study for KALBITOR (Ecallantide) in the Treatment of Acute Attacks of Hereditary Angioedema

Hereditary Angioedema (HAE)

United States
Shire

Completed

Phase 1 Study to Assess the Safety, Tolerability, and Pharmacokinetics of Recombinant Human C1 Esterase Inhibitor in Healthy Adult Subjects

Hereditary Angioedema (HAE)

United States
Shire

Completed

Study of C1 Inhibitor (Human) for the Prevention of Angioedema Attacks and Treatment of Breakthrough Attacks in Japanese Subjects With Hereditary Angioedema (HAE)

Hereditary Angioedema (HAE)

Japan
Shire

Completed

EDEMA2: Evaluation of DX-88's Effect in Mitigating Angioedema

Hereditary Angioedema (HAE)
Shire
Dyax Corp.

Completed

A Single Increasing Dose Study to Assess Safety and Tolerability of DX-2930 in Healthy Subjects

Hereditary Angioedema (HAE)

United States
National Cancer Institute (NCI)

Completed

Phase I-II Multiple-Dose Safety and Efficacy Study of a Selective Inhibitor of Cyclooxygenase - 2 (SC-58635) in Hereditary Non-Polyposis Colorectal Cancer (HNPCC) Patients and Carriers

Colorectal Neoplasm | Hereditary Nonpolyposis

United States
Boston Children's Hospital
CureAP4 Foundation

Recruiting

Registry and Natural History Study for Early Onset Hereditary Spastic Paraplegia (HSP)

Hereditary Spastic Paraplegia | SPG50 | SPG47 | SPG51 | SPG52 | AP4-related Hereditary Spastic Paraplegia | Early Onset Hereditary Spastic Paraplegia | SPG4 | SPG3A | SPG15 | SPG11

United States
Byron Lam
National Eye Institute (NEI)

Active, not recruiting

Safety Study of an Adeno-associated Virus Vector for Gene Therapy of Leber's Hereditary Optic Neuropathy (LHON)

Leber's Hereditary Optic Neuropathy

United States
Santhera Pharmaceuticals

Completed

RHODOS Follow-up Single-visit Study (RHODOS-OFU)

Leber's Hereditary Optic Neuropathy

Canada, Germany, United Kingdom
Vaderis Therapeutics AG

Recruiting

Assess Safety and Efficacy of VAD044 in HHT Patients

Hereditary Hemorrhagic Telangiectasia (HHT)

United States, Spain, France, Belgium, Netherlands, Italy
University of Rochester
Livionex Inc

Completed

A Pilot Study to Assess the Preliminary Efficacy of EDTA Eye Drops on Band Keratopathy

Corneal Dystrophy, Band-Shaped

United States
Centre Hospitalier Universitaire de Besancon

Completed

Long Term Cornea Graft Survival Study (BELIEvE)

Keratoconus | Fuchs' Endothelial Dystrophy

France
University Hospital, Rouen

Completed

Comparison of Two Techniques in Achieving Corneal Graft

Fuch's Endothelial Dystrophy

France
Eye Hospital Pristina Kosovo

Enrolling by invitation

Fresh Corneal Lenticule Implantation in Macular Corneal Distrophy With Relex Smile Surgery

Macular Corneal Dystrophy

Kosovo

Clinical Trials on Hereditary Paraganglioma-pheochromocytoma

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