Clinical Trials on High-Grade Glioma in Belgium

Total 124 results

University Ghent
Research Foundation Flanders; Special Research Fund, Belgium

Completed

PET Imaging of High-grade Glioma Using 18F-fluoromethylcholine: a Tool for the Early Detection of Tumour Recurrence After Combined Radiochemotherapy?

High-grade Glioma of the Brain

Belgium
Hoffmann-La Roche

Completed

A Study of Bevacizumab (Avastin) in Combination With Temozolomide (TMZ) and Radiotherapy in Paediatric and Adolescent Participants With High-Grade Glioma

High Grade Glioma

United Kingdom, Canada, Austria, Italy, Spain, Sweden, Belgium, Denmark, France, Australia, Czechia, Hungary, Netherlands, Poland
University Hospital, Antwerp
Kom Op Tegen Kanker; Stichting Semmy; Olivia Hendrickx research Fund vzw

Active, not recruiting

Adjuvant Dendritic Cell Immunotherapy for Pediatric Patients With High-grade Glioma or Diffuse Intrinsic Pontine Glioma (ADDICT-pedGLIO)

High Grade Glioma | Diffuse Intrinsic Pontine Glioma

Belgium
Brugmann University Hospital

Completed

A Prolongation of a Clinical Study to Evaluate the Efficacy of an Aqueous Gel Containing 2% (w/w) of Cidofovir, Directly Applied on the Cervix Exhibiting High Grade Squamous Intraepithelial Lesions.

High Grade Cervical Epithelial Neoplasia (CIN2+)

Belgium
Universitaire Ziekenhuizen KU Leuven
Carl Zeiss Meditec AG; Imec

Recruiting

HyperSpectral Imaging in Low Grade Glioma (HSI-LGG-2019)

Low Grade Glioma of Brain

Belgium
Jasper Gerritsen
Massachusetts General Hospital; Universitaire Ziekenhuizen KU Leuven; University... and other collaborators

Recruiting

The SUPRAMAX Study: Supramaximal Resection Versus Maximal Resection for High-Grade Glioma Patients (ENCRAM 2201) (SUPRAMAX)

Glioblastoma | Brain Neoplasms | Astrocytoma, Grade III | High-grade Glioma | Astrocytoma, Grade IV | Glioblastoma, IDH-mutant | Glioblastoma, IDH-wildtype | Glioblastoma Multiforme, Adult | Brain Neoplasm, Primary | Brain Neoplasm, Malignant | Astrocytoma, Malignant | Brain Neoplasms, Adult

United States, Germany, Belgium, Switzerland, Netherlands
Universitair Ziekenhuis Brussel

Completed

Clinical Trial on the Combination of Avelumab and Axitinib for the Treatment of Patients With Recurrent Glioblastoma (GliAvAx)

Recurrent Glioblastoma (WHO-Grade IV Glioma)

Belgium
Universitaire Ziekenhuizen KU Leuven

Unknown

Multimodal MR Imaging in Patients With Glioblastoma Treated With Dendritic Cell Therapy

Malignant Gliomas

Belgium
Universitaire Ziekenhuizen KU Leuven

Completed

Advanced MR Techniques in Detection of Tumor Infiltration and Grading in Gliomas

Gliomas

Belgium
Erasme University Hospital

Recruiting

Complications of High Frequency Jet Ventilation

Bronchoscopy | High-Frequency Jet Ventilation

Belgium
European Organisation for Research and Treatment...
Cooperative Trials Group for Neuro-Oncology (COGNO)

Terminated

Trial in Low Grade Glioma Patients: Wait or Treat (IWOT)

Temozolomide | Low-grade Glioma | Phase III | Wait or Treat

Spain, Australia, Switzerland, France, Belgium, Italy, Austria, Netherlands, United Kingdom, Denmark
Day One Biopharmaceuticals, Inc.
SIOPe Brain Tumor Group LOGGIC Consortium

Recruiting

DAY101 vs. Standard of Care Chemotherapy in Pediatric Patients With Low-Grade Glioma Requiring First-Line Systemic Therapy (LOGGIC/FIREFLY-2)

Low-grade Glioma

United States, Korea, Republic of, France, Germany, Spain, United Kingdom, Belgium, Denmark, Canada, Italy, Finland, Australia, Ireland, Switzerland, Netherlands, Czechia, Greece, New Zealand, Slovenia, Sweden, Hungary, Singapore, A... and more
Catherine Vanpachterbeke

Completed

Preventing Invasive Cervical Cancer: The Importance of Expectant Management in Young Women With High-grade Pre-cancerous Lesions

High-Grade Squamous Intraepithelial Lesions

Belgium
Cliniques universitaires Saint-Luc- Université...

Withdrawn

Functional and Clinical Impact of CYP3A Genetic Polymorphisms on Statin Therapy

Patients With High Cholesterol Levels Needing a Lipid-lowering Therapy

Belgium
Stichting Hemato-Oncologie voor Volwassenen Nederland

Active, not recruiting

DA-EPOCH-R Induction Followed by Nivolumab Consolidation in Newly Diagnosed MYC, BCL2 and/or BCL6 Rearranged HGBL (HO152)

Lymphoma, B-Cell | Non Hodgkin Lymphoma | High-grade B-cell Lymphoma | MYC Translocation | BCL-2 Translocation

Netherlands, Belgium
Philips Electronics Nederland B.V. acting through...

Completed

Mitral Valve Regurgitation Quantification From 3D Color Doppler Ultrasound - Standard of Care Data Collection

Mitral Valve Regurgitation of Any Grade

Belgium
University Ghent
Distrac

Completed

Effectivity and Efficiency of Turning Frequencies: a Randomised Controlled Trial

Pressure Ulcer Lesions (Grade 2 or More)

Belgium
Inovio Pharmaceuticals

Completed

REVEAL 1 (Evaluation of VGX-3100 and Electroporation for the Treatment of Cervical HSIL) (REVEAL 1)

Cervical Dysplasia | Cervical High Grade Squamous Intraepithelial Lesion | HSIL

United States, Spain, Portugal, Italy, Philippines, Thailand, Slovakia, Lithuania, Estonia, Belgium, South Africa, Germany, Argentina, United Kingdom, Poland, Puerto Rico, Finland, Mexico, Peru
Universitaire Ziekenhuizen KU Leuven

Recruiting

Longitudinal Analysis of the Health-related Quality of Life in Glioma Patients (Glioma2015)

Glioma of Brain

Belgium
European Organisation for Research and Treatment...

Completed

Trabectedin for Recurrent Grade II/III Meningioma

Recurrent High Grade Meningioma

Belgium, Netherlands, France, Spain, Germany, United Kingdom, Italy, Norway, Switzerland, Austria
Autonomic Technologies, Inc.

Completed

Pathway M-1: Sphenopalatine Ganglion Stimulation for the AcuteTreatment of High Disability Migraine Headache (Pathway M-1)

High Frequency, High Disability Migraine

Belgium, Denmark, Spain
Jasper Gerritsen
University Medical Center Groningen; University Hospital, Ghent; Medical Center... and other collaborators

Recruiting

The SAFE-Trial: Awake Craniotomy Versus Surgery Under General Anesthesia for Glioblastoma Patients. (SAFE)

Glioblastoma | Brain Neoplasms | Brain Cancer | Brain Tumor | Glioblastoma Multiforme | Astrocytoma, Grade IV | Glioblastoma Multiforme of Brain

Netherlands, Belgium
ROX Medical, Inc.

Completed

Registry to Evaluate the ROX COUPLER in Patients With Resistant or Uncontrolled Hypertension

Hypertension | Blood Pressure, High | Blood Pressure, Resistant | Blood Pressure, Uncontrolled

United Kingdom, Netherlands, Belgium
Salvia BioElectronics

Not yet recruiting

Randomized, Double-blind, Sham-controlled Trial to Investigate Combined Occipital and Supra-orbital Neuromodulation in Resistant Migraine. (RECLAIM)

Chronic Migraine | High Frequency Episodic Migraine

Belgium
Aprea Therapeutics

Completed

p53 Activation in Platinum-Resistant High Grade Serous Ovarian Cancer, a Study of PLD With APR-246

High-grade Serous Ovarian Cancer

Spain, United Kingdom, Belgium
La Jolla Pharmaceutical Company

Recruiting

A Study of LJPC-501 in Paediatric Patients With Hypotension Associated With Distributive or Vasodilatory Shock

Septic Shock | Catecholamine-resistant Hypotension (CRH) | Distributive Shock | High Output Shock

Belgium, Lithuania
Universitair Ziekenhuis Brussel

Active, not recruiting

Intra-tumoral Ipilimumab Plus Intravenous Nivolumab Following the Resection of Recurrent Glioblastoma (GlitIpNi)

Glioblastoma

Belgium
Bart Neyns
Pfizer

Completed

A Randomized Phase II Clinical Trial on the Efficacy of Axitinib as a Monotherapy or in Combination With Lomustine for the Treatment of Patients With Recurrent Glioblastoma (AxiGII)

Glioblastoma Multiforme

Belgium
University Hospital, Lille
Institut National de la Santé Et de la Recherche Médicale, France; Hemerion...

Recruiting

Dose Finding for Intraoperative Photodynamic Therapy of Glioblastoma (DOSINDYGO)

Glioblastoma

France, Belgium
University Hospital, Antwerp

Recruiting

Adjuvant Dendritic Cell-immunotherapy Plus Temozolomide in Glioblastoma Patients (ADDIT-GLIO)

Glioblastoma Multiforme of Brain

Belgium
Cliniques universitaires Saint-Luc- Université...

Unknown

Prolonged Adjuvant Temozolomide vs "Stop & Go" in Glioblastoma Patients (PATSGO)

Glioblastoma

Belgium
Universitaire Ziekenhuizen KU Leuven

Unknown

Ophthalmological Screening and Follow-up of Optic Pathway Gliomas in Children With Neurofibromatosis Type 1.

Neurofibromatosis Type 1

Belgium
Atrial Fibrillation Network
Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company; Deutsches Zentrum für...

Terminated

Non-vitamin K Antagonist Oral Anticoagulants in Patients With Atrial High Rate Episodes (NOAH)

Atrial High Rate Episodes

Austria, Belgium, Bulgaria, Czechia, France, Germany, Greece, Hungary, Italy, Netherlands, Poland, Portugal, Romania, Spain, Sweden, Ukraine, United Kingdom, Denmark
Maastricht University Medical Center

Completed

Comparison of Standard Neuronavigation With Intraoperative Magnetic Resonance Imaging (MRI) for the Neurosurgical Treatment of Malignant Brain Tumors (RACING)

Glioblastoma Multiforme

Netherlands, Belgium
Universitair Ziekenhuis Brussel

Not yet recruiting

A Clinical Trial on Combined (Neo-)Adjuvant Intravenous Plus Intracranial Administration of Ipilimumab and Nivolumab in Recurrent Glioblastoma (NEO-GLITIPNI)

Recurrent Glioblastoma

Belgium
Bart Neyns

Terminated

Effect of Radiation Therapy Plus Temozolomide Combined With Cilengitide or Cetuximab on the 1-year Overall Survival of Patients With Newly Diagnosed MGMT-promoter Unmethylated Glioblastoma

Glioblastoma

Belgium
Marc Arbyn
University Hospital, Ghent; Universitair Ziekenhuis Brussel; University Hospital... and other collaborators

Active, not recruiting

Validation of Human Papillomavirus Assays and Collection Devices for Self-samples and Urine Samples (VALHUDES)

Cervical Intraepithelial Neoplasia Grade 2/3

Belgium
Radboud University Medical Center

Completed

Pharmacokinetics of Micafungin Given Twice Weekly Intravenously Compared to Micafungin Given Daily to Patients at Risk for Developing an Invasive Fungal Disease (MATADOR)

Allogeneic Stem Cell Transplant | Acute Myeloid Leucaemia | Myelo Dysplastic Syndrome | Acute Graft Versus Host Disease Grade II-IV

Netherlands, Belgium
Novartis Pharmaceuticals

Completed

A Phase 2 Study of BGJ398 in Patients With Recurrent GBM

Recurrent Glioblastoma or Other Glioma Subtypes

Spain, Belgium, United States, Switzerland, Australia, Netherlands
Boehringer Ingelheim

Recruiting

A Study to Determine How BI 907828 (Brigimadlin) is Taken up in the Tumor (Phase 0) and to Determine the Highest Dose of BI 907828 (Brigimadlin) That Could be Tolerated (Phase 1a) in Combination With Radiation Therapy in People With a Brain Tumor Called Glioblastoma

Glioblastoma

Belgium, Spain, United States
Merck Sharp & Dohme LLC

Active, not recruiting

Pembrolizumab With Chemotherapy and MK-4830 for Treating Participants With Ovarian Cancer (MK-4830-002)

Ovarian Carcinoma | High-grade Serous Ovarian Carcinoma

Korea, Republic of, Spain, Poland, United States, Belgium, Canada, Chile, Israel, Italy, Singapore, Taiwan
KU Leuven

Unknown

International Lung UltraSound Analysis (ILUSA) Study (ILUSA)

Pneumonia, Viral | Pneumonia | Pregnancy Related | Pregnancy, High Risk | COVID | Diagnoses Disease | Pregnancy Complications, Infectious | Pregnancy Disease

Belgium, Italy, United Kingdom
Universitaire Ziekenhuizen KU Leuven
University Hospital, Ghent; Gasthuis Zusters Antwerpen

Recruiting

Neurocognition After Radiotherapy in CNS- and Skull-base Tumors (NARCiS)

Glioma | Pituitary Adenoma | Brain Tumor | Magnetic Resonance Imaging | Meningioma | Cognition

Belgium
Erasmus Medical Center
Universitaire Ziekenhuizen KU Leuven; University of California, San Francisco; Medical Center Haaglanden

Recruiting

The PROGRAM-study: Awake Mapping Versus Asleep Mapping Versus No Mapping for Glioblastoma Resections (PROGRAM)

Glioblastoma

United States, Belgium, Germany, Netherlands, Switzerland
Basilea Pharmaceutica

Completed

Phase 1/2a Study of Oral BAL101553 in Adult Patients With Solid Tumors or Glioblastoma or High-grade Glioma

Neoplasms

Belgium, United Kingdom, Germany, Switzerland
European Organisation for Research and Treatment...

Completed

Temozolomide and Radiation Therapy With or Without Vatalanib in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Brain and Central Nervous System Tumors

Switzerland, Italy, Belgium, Germany, Netherlands
CureVac

Active, not recruiting

Safety and Tolerability of CVGBM in Adults With Newly Diagnosed MGMT-Unmethylated Glioblastoma or Astrocytoma

Glioblastoma

Belgium, Germany, Netherlands
Aprea Therapeutics

Completed

p53 Suppressor Activation in Recurrent High Grade Serous Ovarian Cancer, a Phase Ib/II Study of Systemic Carboplatin Combination Chemotherapy With or Without APR-246

Platinum Sensitive Recurrent High-grade Serous Ovarian Cancer With Mutated p53

United States, France, Spain, Netherlands, United Kingdom, Belgium, Germany, Sweden
BBB-Therapeutics B.V.

Completed

An Open-label, Phase I/IIa, Dose Escalating Study of 2B3-101 in Patients With Solid Tumors and Brain Metastases or Recurrent Malignant Glioma.

Melanoma | Breast Cancer | Lung Cancer | Malignant Glioma | Brain Metastases

United States, Netherlands, France, Belgium
UCB Biopharma SRL

Terminated

A Study to Test the Efficacy, Safety, and Pharmacokinetics of Rozanolixizumab in Adult Study Participants With Leucine-Rich Glioma Inactivated 1 Autoimmune Encephalitis

Leucine-Rich Glioma Inactivated 1 Autoimmune Encephalitis

United States, Australia, Belgium, France, Germany, Italy, Netherlands, Spain, United Kingdom

Clinical Trials on High-Grade Glioma in Belgium

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