Clinical Trials on Higk Risk Surgery

Total 9589 results

Qilu Hospital of Shandong University

Recruiting

Long-term Effect of High Flow Nasal Canula Therapy on Obstructive Sleep Apnea (HFNC)

Obstructive Sleep Apnea | High Flow Nasal Canula | Continuous Positive Airway Pressure Ventilation

China
Bangladesh Medical Research Council (BMRC)

Unknown

Performance Evaluation of RealDetect™ COVID-19 RT-PCR Kit for the Detection of SARS-CoV-2 Virus

High Sensitivity and Specificity (With 95% Confidence Interval) of RealDetect™ COVID-19 RT-PCR Kit

Bangladesh
Fondazione Policlinico Universitario Agostino Gemelli...

Unknown

NUVOLA TRIAL Open-label Multicentre Study (NUVOLA)

High Grade Serous Ovarian Cancer

Italy
Beijing Ditan Hospital

Unknown

Effect and Safety of Propofol Fumarate for Mother-to-child Blocking of Hepatitis B

Chronic Hepatitis B Infection | High Viral Load

China
Lei Li

Unknown

DNA Methylation for Screening Uterine Cervical Lesions

DNA Methylation | Uterine Cervical Cancer | High Grade Squamous Intraepithelial Lesions | Low Grade Squamous Intraepithelial Lesions

China
Lei Li

Unknown

DNA Methylation for Screening Uterine Cervical Lesions: A Case-control Study

DNA Methylation | Uterine Cervical Cancer | High Grade Squamous Intraepithelial Lesions | Low Grade Squamous Intraepithelial Lesions

China
St. Jude Children's Research Hospital

Completed

Study of the Combination of Crizotinib and Dasatinib in Pediatric Research Participants With Diffuse Pontine Glioma (DIPG) and High-Grade Glioma (HGG)

Diffuse Intrinsic Pontine Glioma | High-grade Glioma

United States
Dana-Farber Cancer Institute
Sanofi; Genzyme, a Sanofi Company

Terminated

Cyclophosphamide and Alemtuzumab In Lymphoma

Non Hodgkin Lymphoma | Diffuse Large B Cell Lymphoma | High-grade B-cell Lymphoma

United States
AIDS Malignancy Consortium
National Cancer Institute (NCI); Memorial Sloan Kettering Cancer Center; Northwestern... and other collaborators

Completed

Health-Related Symptom Questionnaires in Measuring Quality of Life in HIV-Infected Participants Treated or Monitored for Anal Lesions

HIV Infection | High Grade Anal Canal Squamous Intraepithelial Neoplasia

United States
Klinikum Stuttgart
Klinikum Kassel GmbH (COSS-Biobank)

Not yet recruiting

Registry For Children, Adolescents And Adults With Osteosarcoma And Biologically Related Bone Sarcomas (COSS-Registry)

Osteosarcoma | High Grade Sarcoma | Recurrent Osteosarcoma | Bone Sarcoma | Undifferentiated Pleomorphic Sarcoma | Bone Tumor | Extraskeletal Osteosarcoma | Osseous Sarcoma | Parosteal Osteosarcoma | Osteoblastic Osteosarcoma | Chondroblastic Osteosarcoma | Fibroblastic Osteosarcoma | Conventional Osteosarcoma | Conventional... and other conditions
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Dose Adjusted EPOCH Regimen in Combination With Ofatumumab or Rituximab in Treating Patients With Newly Diagnosed or Relapsed or Refractory Burkitt Lymphoma or Relapsed or Refractory Acute Lymphoblastic Leukemia

Recurrent Acute Lymphoblastic Leukemia | Refractory Acute Lymphoblastic Leukemia | Recurrent Burkitt Lymphoma | AIDS-Related Burkitt Lymphoma | Atypical Burkitt/Burkitt-Like Lymphoma | High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements | High Grade B-Cell Lymphoma With MYC, BCL2... and other conditions

United States
Peking University First Hospital
Aerospace Center Hospital

Recruiting

Effect of Urine-guided Hydration on Acute Kidney Injury After CRS-HIPEC

Postoperative Complications | Acute Kidney Injury | Cytoreductive Surgery | Hydration | Diuresis | Hyperthermic Intraperitoneal Chemotherapy

China
University Hospital, Bonn

Recruiting

Predicting Acute-on-Chronic Liver Failure After Surgical Intervention in Chronic Liver Disease (PERSEVERE)

Liver Cirrhosis | Acute-On-Chronic Liver Failure | Surgery | Portal Hypertension | Non-Cirrhotic Portal Hypertension

Germany
Nanjing Medical University

Recruiting

Outcome of Patients Treated With IABP

Coronary Artery Disease | Heart Failure | Acute Coronary Syndrome | Cardiogenic Shock | Left Ventricular Dysfunction | Post-cardiac Surgery | Low Cardiac Output Syndrome

China
St. Louis University

Completed

Gyn Onc Prehab Study

Quality of Life | Cervical Cancer | Gynecologic Cancer | Ovarian Cancer | Surgery | Endometrial Cancer | Treatment Adherence

United States
China Academy of Chinese Medical Sciences

Completed

the Method of Cotton Padding Promoting the Rectovaginal Fistula Surgery

Healing of the Wound After Rectovaginal Fistula Surgery

China
Yingchun Ma

Completed

Clinical Effect Evaluation of Laparoscopic Surgery for Ovarian Benign Tumors by Different Approaches

Laparoscope | Malignant Ovarian Tumor | Single-site Surgery

China
Stanford University
SPR Therapeutics, Inc.

Withdrawn

Using Peripheral Nerve Stimulation (PNS) to Treat Chronic Post-surgical Pain (CPSP) After Knee Surgery

Postoperative Pain | Knee Injuries | Surgery | Total Knee Arthroplasty | Knee Pain Chronic | Chronic Postoperative Pain | Injury; Nerve, Peripheral, Multiple | Chronic Post-Procedural Pain

United States
Jan Biziel University Hospital No 2 in Bydgoszcz

Unknown

Comparison of Effectiveness of Tonic, High Frequency and Burst Spinal Cord Stimulation in Chronic Pain Syndromes

CRPS (Complex Regional Pain Syndromes) | Failed Back Surgery Syndrome

Poland
University of Washington
John L. Locke Jr. Charitable Trust

Terminated

Text Message Intervention to Improve Cardiac Rehab Participation

Myocardial Infarction | Percutaneous Coronary Intervention | Coronary Artery Bypass Surgery | Chronic Stable Angina | Left Ventricular Assist Device | Heart Transplant | Chronic Stable Heart Failure | Heart Valve Repair or Replacement

United States
National Cheng-Kung University Hospital

Completed

Evaluating the Relationship of Morphine Consumption and Pain-related Molecules in Hepatic Surgical Patients

Pain | Huntington Disease | Hepatic Surgery

Taiwan
University of California, San Diego
University of California, Los Angeles; University of California, Davis; University... and other collaborators

Completed

A Complex Contraception Registry

Epilepsy | Cardiovascular Disease | Diabetes | Cancer | Lupus Erythematosus, Systemic | Migraine | Neurological Disorders | Bariatric Surgery Candidate | Organ or Tissue Transplant; Complications | Other Hematologic Conditions | Other Venous Embolism and Thrombosis

United States
Uppsala University
AstraZeneca

Unknown

Improving Glucose and Lipid Metabolism Through Caloric Restriction Using Diet or Surgery (CRUDOS) (CRUDOS)

Weight Loss | Bariatric Surgery Candidate | Type2 Diabetes | Insulin Sensitivity | Metabolism and Nutrition Disorder | Metabolism Disorder, Glucose

Sweden
German Heart Institute
Miltenyi Biomedicine GmbH

Completed

Bypass Surgery and CD133 Marrow Cell Injection for Treatment of Ischemic Heart Failure (Cardio133)

Congestive Heart Failure | Previous Myocardial Infarction | Coronary Artery Disease With Need for Bypass Surgery | Myocardial Ischemia, Angina Pectoris

Germany
University of Turku
Brigham and Women's Hospital

Active, not recruiting

Prospective Project to Identify Biomarkers of Morbidity and Mortality in Cardiovascular Interventional Patients (CAREBANK)

Coronary Artery Disease | Atrial Fibrillation | Aortic Valve Stenosis | Aortic Valve Disease | Cardiac Surgery | Cardiac Arrythmias | Mitral Valve Disease | Cardiac Tumor

Finland
Novartis Pharmaceuticals

Completed

Study of Efficacy and Safety of Bimagrumab in Patients After Hip Fracture Surgery

Muscle Wasting (Atrophy) After Hip Fracture Surgery

Colombia, Belgium, Hungary, Taiwan, Spain, Czechia, United States, France, Germany, Turkey, Japan, Russian Federation, United Kingdom, Argentina, Australia, Mexico, Chile, Switzerland, Austria
University of Roma La Sapienza

Completed

The Recovery of Reaching Movement in Breast Cancer Survivors: Two Different Rehabilitative Protocols in Comparison

Pain | Pain, Postoperative | Breast Surgery | Breast Cancer | Pain, Chronic | Breast Cancer Lymphedema | Mastectomy; Lymphedema

Italy
University of Zurich

Unknown

Associating Liver Partition With Portal Vein Ligation for Staged Hepatectomy (ALPPS) vs. Two-Stage Hepatectomy (TSH) for Marginally Resectable Colorectal Liver Metastases (CRLM) (ALPPSforCRLM)

Liver Diseases | Liver Neoplasms | Hepatectomy | Surgery | Secondary Malignant Neoplasm of Liver | Colon Cancer Liver Metastases | Malignant Neoplasm of Large Intestine Metastatic to Liver

Switzerland
Mespere Lifesciences Inc.

Unknown

Comparison of Central Venous Oxygen Saturation Measurements by Non-invasive Mespere Venous Oximeter and Central Venous Catheter

Sepsis | Post Cardiac Surgery Low Output Syndrome Requiring Inotropic/Vasopressor Therapy | Cardiogenic Shock Post Myocardial Infarction | Hypoxemic Respiratory Failure.

Canada
University Hospital, Basel, Switzerland

Completed

Long-term Mortality in Diabetics Undergoing Major Surgery

Diabetes Mellitus | Coronary Heart Disease | Major Non-cardiac Surgery

Switzerland
Jacobs University Bremen gGmbH
Dr. Becker Hospital Group; Dr. Becker Klinik Möhnesee; Dr. Becker Burg-Klinik... and other collaborators

Completed

Feasibility and Benefits of Digital Services During the COVID19 Pandemic (AnhandCOV19)

Anxiety | Communication | Psychological Distress | Health Risk Behaviors | Healthy Lifestyle | Psychological Adjustment | Psychological Stress | Psychological Disorder | Behavior, Health | Psychological Disease | Psychosomatic Disorder | Psychological Adaptation | Health Care Seeking Behavior | Psychological Disability and other conditions

Germany
Frederiksberg University Hospital

Active, not recruiting

Prevalence of Self-disclosed Knee Trouble and Use of Treatments Among Elderly Individuals

Pain | Knee Osteoarthritis | Complementary Therapies | Survey, Family Life

Denmark
Sociedad de Lucha Contra el Cáncer del Ecuador

Not yet recruiting

Omic Technologies Applied to the Study of B-cell Lymphoma for the Discovery of Diagnostic and Prognosis Biomarkers

Neoplasms | Lymphoma, B-Cell | Cancer | Non Hodgkin Lymphoma | Diffuse Large B Cell Lymphoma | High-grade B-cell Lymphoma | Metabolomics

Ecuador
SonoClear AS

Recruiting

SonoClear Acoustic Coupling Fluid (ACF) Mimicking Brain Tissue

Glioblastoma | High Grade Glioma | Low-grade Glioma | Brain Tumour

Germany, Slovakia, Italy
Nationwide Children's Hospital

Recruiting

A Pilot Study of Larotrectinib for Newly-Diagnosed High-Grade Glioma With NTRK Fusion

High Grade Glioma | Diffuse Intrinsic Pontine Glioma

United States, Australia, Canada, Germany
Sunnybrook Health Sciences Centre

Completed

Overlooked Population at Risk for AIN.

Cervical Cancer | High Grade Cervical Dysplasia

Canada
Masonic Cancer Center, University of Minnesota

Active, not recruiting

FT596 With Rituximab as Relapse Prevention After Autologous HSCT for NHL

Non Hodgkin Lymphoma | Diffuse Large B Cell Lymphoma | NHL | High-grade B-cell Lymphoma

United States
Unity Health Toronto

Recruiting

Superficial Parasternal Intercostal Plane Block in Cardiac Surgery Trial (EPOCH)

Chronic Pain | Anesthesia, Local | Opioid Use Disorder | Post-operative Pain | Post-cardiac Surgery | Post-operative Delirium

Canada
Umeå University
Karolinska University Hospital; Sahlgrenska University Hospital, Sweden; University... and other collaborators

Recruiting

Survival, Quality of Life and Resectability in Locally Advanced Pancreatic Cancer (SQUARE)

Quality of Life | Surgery | Pancreas Adenocarcinoma | Chemotherapy Effect | Pancreas Cancer | Pancreas Neoplasm | Pancreas Disease | Locally Advanced Pancreatic Adenocarcinoma | Borderline Resectable Pancreatic Adenocarcinoma

Sweden
Beijing Anzhen Hospital

Recruiting

Outcomes of Mitral Valve Surgery in Patients Affected by Rheumatic Heart Disease

Outcomes of Mitral Valve Surgery in Patients Affected by Rheumatic Heart Disease

China
University of Florence
Sandro Gelsomino; Edvin Prifti; Francesco Cabrucci; Marco Bugetti; Orlando Parise; Aleksander...

Recruiting

Post-Surgery Extracorporeal Life Support (PC-ECLS)

Cardiogenic Shock | Extracorporeal Membrane Oxygenation Complication | Post-cardiac Surgery | Extracorporeal Life Support | Post Cardiac Arrest Syndrome

Italy
Medical University of Lublin

Enrolling by invitation

Cerebrolysin in Prevention of Postoperative Delirium in Cardiac Surgery (Cereb-POD)

Neurocognitive Disorders | Critical Illness | Cardiac Disease | Brain Damage | Surgery-Complications

Poland
Bahçeşehir University

Completed

Comparison of the Effect of Traditional Method and Eras Protocol in Obesity Surgery

Pain, Postoperative | Diabetes | Nausea | Obesity, Morbid | Bariatric Surgery Candidate | Postoperative Nausea and Vomiting | Postoperative Nausea | Post Procedural Discharge | DVT | Obesity Adult Onset | ERAS | Obesity Associated Disorder | Ache

Turkey
University Hospital, Montpellier
Thermo Fisher Scientific, Inc

Completed

Prediction of Inflammatory Response and Hypotensive Syndrome After Cardiac Surgery by Preoperative Copeptin Level (MicorSIRS)

Stress Response | Systemic Inflammatory Response Syndrome (SIRS) | Postoperative Vasodilation Syndrome | Cardiac Surgery Prognosis | Tissue Oxygenation and Post-ischemic Response

France
CellCentric Ltd.

Recruiting

Study to Evaluate CCS1477 in Haematological Malignancies

Acute Myeloid Leukemia | Multiple Myeloma | Non Hodgkin Lymphoma | Peripheral T Cell Lymphoma | Haematological Malignancy | Higher-risk Myelodysplastic Syndrome

United Kingdom, United States, France, Sweden, Spain
University of Minnesota

Enrolling by invitation

The Professional Peer Resilience Initiative (PPRI)

Stress | Stress, Psychological | Secondary Traumatic Stress | Anxiety | Post Traumatic Stress Disorder | Anxiety State | Stress Disorder | Stress Related Disorder | Trauma, Psychological | Stress Reaction | Professional Quality of Life | Stress Risk | Mental Resilience | Emotional Resilience

United States
National Cancer Institute (NCI)

Recruiting

A Study Combining the Peposertib (M3814) Pill With Standard Chemotherapy in Patients With Ovarian Cancer With an Expansion in High Grade Serous Ovarian Cancer and Low Grade Serous Ovarian Cancer

Recurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | Ovarian Seromucinous Carcinoma | Ovarian Undifferentiated Carcinoma | Fallopian Tube Transitional Cell Carcinoma | Primary Peritoneal High Grade Serous Adenocarcinoma | Fallopian Tube Clear... and other conditions

United States
ProgenaBiome

Recruiting

A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Autism

Autism Spectrum Disorder | Autistic Disorder | Autism | Autism, Akinetic | Autism; Atypical | Autism; Psychopathy | Autism Fragile Syndrome X | Autism With High Cognitive Abilities | Autism-Related Speech Delay | Autism, Susceptibility to, 6 | Autism Spectrum Disorder High-Functioning | Autistic Thinking | Autism... and other conditions

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Combination Chemotherapy in Treating Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia, Lymphoblastic Lymphoma, Burkitt Lymphoma/Leukemia, or Double-Hit Lymphoma/Leukemia

Recurrent Adult Lymphoblastic Lymphoma | Recurrent High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements | Refractory High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements | Recurrent Acute Lymphoblastic Leukemia | Refractory Acute Lymphoblastic Leukemia | Recurrent... and other conditions

United States
Northwell Health

Recruiting

Surgical Tissue Flap to Bypass the Blood Brain Barrier in Glioblastoma

Glioblastoma | Brain Cancer | Glioblastoma Multiforme | High Grade Glioma | GBM | Glioma, Malignant | Glioblastoma Multiforme, Adult

United States

Clinical Trials on Higk Risk Surgery

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