Clinical Trials on Hypercholesterolemia, Familial, 2

Total 13031 results

Medical University of South Carolina
National Institute of Mental Health (NIMH); Muhimbili University of Health...

Completed

Impact of Integrated HIV/NCD Screening on HIV Testing Uptake and Engagement in HIV Care In Kisarawe, Tanzania

Hypertension | Diabetes Mellitus, Type 2 | Human Immunodeficiency Virus

Tanzania
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Establish The Benefits Of Using Various Starting Doses Of Atorvastatin On Achievement Of Cholesterol Targets (ACTFAST) (ACTFAST)

Diabetes Mellitus, Type 2 | Dyslipidemia | Peripheral Vascular Disease | Coronary Arteriosclerosis | Cerebrovascular Accident

Italy, Spain, Canada, United Kingdom, Cameroon
Cambridge University Hospitals NHS Foundation Trust
Imperial College Healthcare NHS Trust; Royal Cornwall Hospitals Trust

Unknown

Assessment of Olfactory Dysfunction in SARS CoV-2 (COVID-19) Infection (ODYSSI)

Quality of Life | Anosmia | SARS-CoV-2 | COVID19 | Olfactory Disorder | Microsomia | Smell Disorder

United Kingdom
German Breast Group
Roche Pharma AG; Celgene Corporation

Completed

Nanoparticle-based Paclitaxel vs Solvent-based Paclitaxel as Part of Neoadjuvant Chemotherapy for Early Breast Cancer (GeparSepto) (GeparSepto)

Inflammatory Breast Cancer | HER-2 Positive Breast Cancer | Tubular Breast Cancer Stage II | Mucinous Breast Cancer Stage II | Breast Cancer Female NOS | Invasive Ductal Breast Cancer | Tubular Breast Cancer Stage III | Inflammatory Breast Cancer Stage IV

Germany
Radboud University Medical Center

Unknown

Muscle Relaxation in Myopathies With Positive Muscle Phenomena

Myotonic Dystrophy Type 2 | McArdle Disease | Nemaline Myopathy Type 6
German Breast Group
GlaxoSmithKline; Roche Pharma AG; Teva Pharmaceuticals USA

Completed

Addition of Carboplatin to Neoadjuvant Therapy for Triple-negative and HER2-positive Early Breast Cancer (GeparSixto)

Inflammatory Breast Cancer | HER-2 Positive Breast Cancer | Tubular Breast Cancer Stage II | Mucinous Breast Cancer Stage II | Breast Cancer Female NOS | Invasive Ductal Breast Cancer | Tubular Breast Cancer Stage III | Inflammatory Breast Cancer Stage IV

Germany
University of Washington
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Central Obesity and Disease Risk in Japanese Americans

Heart Diseases | Cardiovascular Diseases | Hypertension | Obesity | Diabetes Mellitus | Atherosclerosis | Insulin Resistance | Hyperinsulinism | Coronary Arteriosclerosis | Metabolic Syndrome X | Diabetes Mellitus, Non-insulin Dependent
Assembly Biosciences

Recruiting

A Study to Assess the Safety, Pharmacokinetics, and Antiviral Activity of ABI-5366 in Healthy Participants and Participants Seropositive for HSV-2 With Recurrent Genital Herpes

Recurrent Genital Herpes Simplex Type 2

New Zealand
Institut National de la Santé Et de la Recherche...

Recruiting

Modifying Factors in Striated Muscle Laminopathies (LMNAModifier)

Laminopathies | Emery Dreifuss Muscular Dystrophy 2 | LMNA-Related Congenital Muscular Dystrophy | Dilated Cardiomyopathy-1A

France
Frantz Viral Therapeutics, LLC
M.D. Anderson Cancer Center; University of Michigan; The Cleveland Clinic; Amarex... and other collaborators

Recruiting

Artesunate Vaginal Inserts for the Treatment of Cervical Intraepithelial Neoplasia (CIN2/3) (ART-CIN_IIB)

HPV Infection | CIN 2/3 | Cervical Dysplasia | Pre-Cancerous Dysplasia | HPV Related Disease

United States
Karolinska Institutet
Lantmännen

Completed

Effect of Broccoli Sprout Extract in Patients With Chronic Kidney Disease With Diabetes Type 2 (INITIATE)

Diabetes Mellitus, Type 2 | Chronic Kidney Disease stage4 | Chronic Kidney Disease Stage 3B

Sweden
Nanyang Technological University
Tan Tock Seng Hospital; Ministry of Health, Singapore

Completed

Diabetes Footcare Companion App for Patients and Carers

Diabetes Mellitus, Type 2 | Diabetic Foot | Diabetic Foot Infection | Ulcer Foot | Diabetes Mellitus Foot Ulcer | Ulcer, Leg

Singapore
Nantes University Hospital
National Research Agency, France

Completed

Pathological Findings of Fatal COVID-19 (HISTOCOVID)

Covid19 | Respiratory Distress Syndrome | SARS-CoV-2 | Intensive Care Units | Pathology

France
Guangdong Provincial People's Hospital

Withdrawn

Safety and Long-term Effects of COVID-19 Vaccines in Patients With Pulmonary Tumor (CoVac-Lung)

Vaccine Adverse Reaction | Lung Cancer | COVID-19 Pneumonia | SARS-CoV-2 Acute Respiratory Disease | Pulmonary Nodule, Solitary | Pulmonary Nodule, Multiple

China
Neurotech Pharmaceuticals
University of California, San Francisco

Completed

Retinal Imaging in CNTF -Releasing Encapsulated Cell Implant Treated Patients for Early-stage Retinitis Pigmentosa

Retinitis Pigmentosa | Usher Syndrome Type 2 | Usher Syndrome Type 3

United States
APR Applied Pharma Research s.a.

Withdrawn

Inhaled ZYESAMI (Aviptadil Acetate) for Treatment of Severe COVID-19 (AVICOVID-3)

SARS-CoV 2 | COVID | ARDS | Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS) | Dyspnea | ALI
Murdoch Childrens Research Institute
Royal Children's Hospital

Completed

What is the Incidence of an Immune Disorder in Children With Invasive Pneumococcal Disease (IPD)?

Primary Immunodeficiency | Invasive Pneumococcal Disease, Protection Against | Invasive Pneumococcal Disease, Recurrent Isolated, 1 | Invasive Pneumococcal Disease, Recurrent Isolated, 2

Australia, New Zealand
Cwm Taf University Health Board (NHS)
Cardiff University; Imperial College London; University of Oxford

Completed

Characterisation of the Immune Response to SARS-CoV-2 Infection / COVID-19 in Type 1 Diabetes

Diabetes Mellitus, Type 1 | SARS-CoV2 Infection

United Kingdom
University Hospital Erlangen

Completed

Pediatric SARS-CoV-2 Infections: Course of COVID-19, Immune Responses, Complications and Long-term Consequences (PEDCOVID-19)

Hypohidrotic Ectodermal Dysplasia

Germany
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Benefits Of Using Various Starting Doses Of Atorvastatin On Achievement Of Cholesterol Targets (ACTFAST 2)

Diabetes Mellitus, Type 2 | Dyslipidemia | Peripheral Vascular Disease | Coronary Arteriosclerosis | Cerebrovascular Accident

Greece, Ireland, Russian Federation, Slovakia, Poland, Hungary, Portugal, Switzerland
Hendry Irawan

Completed

Short Duration Hyperbaric Oxygen Therapy to Improve HbA1c, Leukocyte, and Serum Creatinine

Type II Diabetes Mellitus | Diabetic Foot Ulcer | Hyperbaric Oxygen Therapy
Sanofi
UNC Lineberger Comprehensive Cancer Center

Completed

A Study Evaluating INIPARIB in Combination With Chemotherapy to Treat Triple Negative Breast Cancer Brain Metastasis

Brain Metastases | Estrogen Receptor Negative (ER-Negative) Breast Cancer | Progesterone Receptor Negative (PR-Negative) Breast Cancer | Human Epidermal Growth Factor Receptor 2 Negative (HER2-Negative) Breast Cancer

United States
Genzyme, a Sanofi Company

Approved for marketing

Alglucosidase Alfa Temporary Access Program (ATAP)

Glycogen Storage Disease Type II (GSD-II) | Acid Maltase Deficiency Disease | Glycogenosis 2 | Pompe Disease (Late-Onset)

United States
G.V. (Sonny) Montgomery VA Medical Center

Unknown

Herpes Simplex Type 2 Co-infection in Veterans With Chronic Hepatitis C

Hepatitis C Virus Infection | Infection | Herpesvirus 2, Human

United States
University of Pennsylvania
United States Department of Defense; National Institutes of Health (NIH); National... and other collaborators

Recruiting

UPenn Observational Research Repository on Neurodegenerative Disease (UNICORN)

Frontotemporal Degeneration(FTD) | Primary Progressive Aphasia(PPA) | Familial Frontotemporal Lobar Degeneration (fFTLD) | Amyotrophic Lateral Sclerosis(ALS) | Lewy Body Disease(LBD) | Progressive Supranuclear Palsy(PSP) | Corticobasal Syndrome(CBS) | Posterior Cortical Atrophy(PCA) | Alzheimer's Disease(AD)

United States
Steno Diabetes Center Copenhagen
Rigshospitalet, Denmark

Recruiting

Next Generation Advanced Insulin Delivery System in Adults With Diabetes and Advanced Renal Disease

Diabetes Mellitus, Type 2 | Diabetes Mellitus, Type 1 | Hemodialysis | Peritoneal Dialysis | Chronic Kidney Disease | Dialysis

Denmark
Biohaven Pharmaceuticals, Inc.

Active, not recruiting

Trial in Adult Subjects With Spinocerebellar Ataxia

Spinocerebellar Ataxias | Spinocerebellar Ataxia Genotype Type 1 | Spinocerebellar Ataxia Genotype Type 2 | Spinocerebellar Ataxia Genotype Type 3 | Spinocerebellar Ataxia Genotype Type 6 | Spinocerebellar Ataxia Genotype Type 7 | Spinocerebellar Ataxia Genotype Type 8 | Spinocerebellar Ataxia Genotype...

United States
Microclinic International
Royal Health Awareness Society (RHAS); Jordanian Ministry of Health (MoH)

Completed

Microclinic Social Network Behavioral Health Trial in Jordan

Hyperglycemia | Hypertension | Obesity | Diabetes Mellitus, Type 2 | Diabetes Mellitus | Diabetes | Body Weight | Weight Loss | Blood Pressure | Weight Gain | Social Behavior | Weight, Body | Glucose, High Blood | Lifestyle, Healthy | Weight Change, Body | Behavior, Health | Lifestyle Risk Reduction | Blood Pressure, High | Hyperglycaemia... and other conditions

Jordan
Pfizer

Completed

A Dose Escalation Study Of PF-06801591 In Melanoma, Head And Neck Cancer (SCCHN), Ovarian, Sarcoma, Non-Small Cell Lung Cancer, Urothelial Carcinoma or Other Solid Tumors

NSCLC | SCCHN | Part 1 | MELANOMA | OVCA | SARCOMA | OTHER SOLID TUMORS | Part 1 and 2 | UROTHELIAL CARCINOMA

United States, Korea, Republic of, Russian Federation, Poland, Malaysia, Bulgaria, Ukraine
University of Sao Paulo General Hospital

Completed

Characteristics and Outcomes of Patients With COVID-19 Admitted to the ICU (EpiCoV-Brazil)

SARS-CoV 2 | Critical Illness | Corona Virus Infection | Respiratory Distress Syndrome, Adult

Brazil
Results Group LLC
Southern Connecticut State University

Completed

Assistive ExoSkeletons to Enable Wearable Rehabilitation Robotics

Diabetic Foot Ulcer | Diabetic Foot Ulcer Associated With Type II Diabetes Mellitus

United States
Dicerna Pharmaceuticals, Inc., a Novo Nordisk company

Recruiting

Safety & Efficacy of DCR-PHXC in Patients With PH1/2 and ESRD (PHYOX7)

End Stage Renal Disease | Primary Hyperoxaluria Type 2 | Primary Hyperoxaluria Type 1

Germany, Spain, United States, United Kingdom, Italy, United Arab Emirates, Lebanon, Morocco, France, Romania
Renalytix AI, Inc.

Active, not recruiting

Prospective Decision Impact Trial of KidneyIntelX

Diabetic Kidney Disease | Chronic Kidney Disease, Stage 3 (Moderate) | Chronic Kidney Disease Stage 2 | Chronic Kidney Disease Stage 1

United States
Rennes University Hospital

Completed

Human Ab Response & immunoMONItoring of COVID-19 Patients (HARMONICOV)

Acute Respiratory Distress Syndrome | SARS-CoV-2 Coronavirus

France
RenJi Hospital
Peking University First Hospital; Shanghai Zhongshan Hospital; First Affiliated... and other collaborators

Recruiting

Frequency, Clinical Phenotype and Genetic Analysis of Heritable Kidney Cancer Syndromes

Kidney Cancer | Renal Cell Carcinoma | ALK Gene Mutation | MET Gene Mutation | HLRCC | Renal Tumor Histology | Cutaneous Leiomyoma | BAP1 Tumor Predisposition Syndrome | VHL Syndrome | Birt-Hogg-Dube Syndrome | Familial Renal Cancer | FLCN Gene Mutation | FH Gene Mutation | Cutaneous Leiomyomata With Uterine Leiomyomata

China
University College, London
Washington University School of Medicine; University of Washington; Alzheimer... and other collaborators

Not yet recruiting

A Trial Evaluating the Effect of NIO752 on Tau Synthesis Measured by a Process Known as SILK (NIO-SILK)

Alzheimer Disease | Autosomal Dominant Alzheimer Disease Due to Mutation of Presenilin 1 (Disorder) | Autosomal Dominant Alzheimer Disease Due to Mutation of Presenilin 2 (Disorder) | Autosomal Dominant Alzheimer Disease Due to Mutation of Amyloid Precursor Protein (Disorder)
Prof. Dr. Folkert W. Asselbergs
Radboud University Medical Center; University Medical Center Groningen; UMC Utrecht and other collaborators

Not yet recruiting

Check@Home: General Population Screening for Early Detection of Atrial Fibrillation and Chronic Kidney Disease

Diabetes Mellitus, Type 2 | Chronic Kidney Diseases | Atrial Fibrillation
RenJi Hospital
The First Affiliated Hospital of Anhui Medical University; Sichuan Academy... and other collaborators

Not yet recruiting

A Retrospective Cohort Study for Main Postoperative Complications After SARS-CoV-2 Infection

Fractures, Bone | Trauma | Liver Cancer | Gynecologic Disease | Pulmonary Cancer | Intestines Cancer
University of Sao Paulo General Hospital

Completed

POST-CABGDM: Empagliflozin in Perioperative CABG (POST-CABGDM)

Coronary Artery Disease | Diabetes Mellitus, Type 2 | Acute Kidney Injury | Coronary Artery Bypass Surgery

Brazil
University of Texas Southwestern Medical Center
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National... and other collaborators

Completed

Improving Chronic Disease Management With Pieces (ICD-Pieces)

Hypertension | Diabetes | Type 2 Diabetes | Chronic Kidney Disease | High BP

United States
Gritstone bio, Inc.

Completed

Study of Self-Amplifying Messenger Ribonucleic Acid (samRNA) Vaccines Against COVID-19 in Healthy Adults and People Living With Human Immunodeficiency Virus (HIV)

COVID-19 | SARS-CoV-2

South Africa
Sohag University

Completed

Type 2 Diabetes Mellitus and Chronic Kidney Disease

Renal Disorder Associated With Type II Diabetes Mellitus

Egypt
University of Washington
Johns Hopkins University; National Institute of Diabetes and Digestive and... and other collaborators

Active, not recruiting

Kidney Precision Medicine Project (KPMP) - COVID-19 Protocol

Covid19 | Acute Renal Failure | Acute Renal Injury | Acute Kidney Failure | Kidney Failure, Acute | Renal Insufficiency, Acute | Acute Renal Insufficiency | Sars-CoV-2 Infection | Acute Kidney Insufficiency | Renal Failure, Acute | Kidney Insufficiency, Acute

United States
Unidad Temporal COVID-19 en Centro Citibanamex

Completed

Effects in Oxygenation and Hypoxic Pulmonary Vasoconstriction in ARDS Secondary to SARS-CoV2 (COVID-19)

Acute Respiratory Distress Syndrome | SARS-CoV-2 Acute Respiratory Disease | Hypoxemia | Hypoxic Pulmonary Vasoconstriction

Mexico
Fondation Ophtalmologique Adolphe de Rothschild

Completed

Association Between Long-term Hydroxychloroquine Treatment and Outcome of a History of Symptoms Suggestive of COVID-19 Infection During the Epidemic Period in France in Patients With Autoimmune Disease (COVCALL)

Rheumatoid Arthritis | Systemic Lupus Erythematosus | SARS-CoV-2 | Psoriatic Arthritis | Sjogren's Syndrome

France
University Hospital, Clermont-Ferrand

Unknown

WHO Covid 19 - Neurological Abnormalities in SARS-CoV-2 ICU Patients (NeuroCovid)

Delirium | SARS-CoV-2 Infection | Encephalopathy | Intensive Care Unit Patient | Neurological Abnormality

France
Pfizer

Terminated

Study Of Bosutinib With Capecitabine In Solid Tumors And Locally Advanced Or Metastatic Breast Cancer

Advanced Breast Cancer (Parts 1 and 2) | Advanced Pancreatic Cancer (Part 1) | Advanced Colorectal Cancer (Part 1) | Advanced Cholangiocarcinoma (Part 1) | Advanced Glioblastoma Multiforme (Part 1)

United States, Spain, Hong Kong, Belgium, Australia, France
McGill University Health Centre/Research Institute...

Recruiting

Longitudinal Natural History Study of Patients With Peroxisome Biogenesis Disorders (PBD)

Peroxisome Biogenesis Disorder | Zellweger Spectrum Disorder | RCDP - Rhizomelic Chondrodysplasia Punctata | D-Bifunctional Protein Deficiency | Alpha-Methylacyl-CoA Racemase Deficiency | Peroxisomal Acyl-CoA Oxidase Deficiency | Peroxisomal Acyl-CoA Oxidase 2 Deficiency | ATP Binding Cassette Subfamily... and other conditions

Canada
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

Acupuncture in Reducing Chemotherapy-Induced Peripheral Neuropathy in Participants With Stage I-III Breast Cancer

Anatomic Stage I Breast Cancer AJCC v8 | Anatomic Stage IA Breast Cancer AJCC v8 | Anatomic Stage IB Breast Cancer AJCC v8 | Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage IIA Breast Cancer AJCC v8 | Anatomic Stage IIB Breast Cancer AJCC v8 | Anatomic Stage III Breast Cancer AJCC v8 | Anatomic... and other conditions

United States
RinuaGene Biotechnology Co., Ltd.

Not yet recruiting

A Study in Subjects With Human Papillomavirus 16 or 18 Associated Cervical Intraepithelial Neoplasia Grade 2 or 3

Cervical Intraepithelial Neoplasia Grade 2/3 | Human Papillomavirus Associated Intraepithelial Neoplasia | Human Papillomavirus Type 16 Infection | Human Papillomavirus Type 18 Infection

Clinical Trials on Hypercholesterolemia, Familial, 2

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