Clinical Trials on Hyponatrémie

Total 146 results

Cumberland Pharmaceuticals

Terminated

Safety and Efficacy of Conivaptan in Hyponatremic Patients With Symptomatic Acute Decompensated Heart Failure (ADHF) (CONVERT-H)

Acute Decompensated Heart Failure | Hyponatremia

India
Institute of Liver and Biliary Sciences, India

Recruiting

To Study Effect of the Combination of Midodrine and Tolvaptan Versus Tolvaptan Alone in Patients With Severe Hyponatremia in Cirrhosis(TOLMINA Trial)

Liver Cirrhosis

India
Sanofi

Completed

DILIPO (DILutIonal HyPOnatremia)

Congestive Heart Failure

United States, Canada, Poland, Romania, Portugal, Sweden, Belgium, Argentina, Denmark, Hungary, Israel, Australia, Chile, South Africa, Greece
Polderman, Kees, H., MD, PhD
University of Pittsburgh

Terminated

Tolvaptan for Patients With Acute Neurological Injuries

Hyponatremia | SIADH

United States
University of Wuerzburg

Completed

Subclassification of the Syndrome of Inappropriate ADH Secretion

Hyponatremia

Germany
Rigshospitalet, Denmark

Completed

The Association Between Hyponatremia and Osteoporosis in Patients With Epilepsy.

Hyponatremia | Metabolic Bone Disease

Denmark
University of North Carolina, Chapel Hill
Medical University of South Carolina; Otsuka America Pharmaceutical; Barnes-Jewish...

Terminated

Pharmacokinetics and Clinical Response of Tolvaptan in Neurocritical Care Patients

Brain Injury | Hyponatremia

United States
Ege University

Recruiting

Investigation of the Effect of Distention Medium Temperature on Image Quality, Hyponatremia Risk, and Post-operative Pain in Operative Hysteroscopy

Post-operative Pain

Turkey
Konkuk University Medical Center
Samsung Medical Center; Seoul St. Mary's Hospital; Korea University Anam Hospital and other collaborators

Unknown

Tolvaptan for Hyponatremia in Cirrhotic Patients With Ascites (TONIC)

Ascites | Hyponatremia

Korea, Republic of
Navitas Pharma
IndiPharm Inc.

Not yet recruiting

Cicletanine in Hypertension With Diabetes: Added Magnesium Preserves Potassium and Sodium (CHAMP)

Diabetes | Hyponatremia | Arterial Hypertension | Hypokalemia
University of Sao Paulo
Fundação de Amparo à Pesquisa do Estado de São Paulo

Completed

Hypertonic Saline Solution in Heart Failure

Heart Failure | Renal Failure | Hyponatremia

Brazil
University Hospital, Caen

Completed

Delirium Related to Proton Pump Inhibitors Use

Delirium | Hyponatremia | Proton Pump Inhibitor Adverse Reaction

France
Universitair Ziekenhuis Brussel

Recruiting

Asymptomatic Bacteriuria, Hyponatremia and Geri-atric Syndrome

Frailty | Asymptomatic Bacteriuria | Geriatric Syndrome | SIADH

Belgium
Helbert Rondon Berrios, MD, MS
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Terminated

Urea for Chronic Hyponatremia

Hyponatremia | Inappropriate ADH Syndrome

United States
University Hospital, Basel, Switzerland

Completed

Effects of Empagliflozin an SGLT2-Inhibitor on Healthy Volunteers With Induced Hypotonic Hyponatremia - the DIVE Study (DIVE)

Inappropriate ADH Syndrome

Switzerland
University Hospital, Grenoble

Recruiting

Urea Therapy for Hyponatremia in Subarachnoid Hemorrhage (NAT-URE)

Subarachnoid Hemorrhage | Hyponatremia | SIADH

France
Hospices Civils de Lyon

Completed

Seizures in Infants Hospitalized in Pediatric Intensive Care Unit for Bronchiolitis (BRONCHIOLITIS)

Seizures | Hyponatremia | Bronchiolitis

France
Hospital Nacional Profesor Alejandro Posadas

Recruiting

Prevalence of Hyponatremia in Dengue Infected Patients: Relationship With Systemic Inflammation. (HINDIP)

Inflammation | Hyponatremia | Dengue

Argentina
Centre Hospitalier Universitaire, Amiens

Recruiting

Association Between Renal and Right Cardiac Functions After Urinary Sodium Depletion Following Cardiac Surgery (DECONGEST)

Cardiorenal Syndrome

France
University Hospital, Basel, Switzerland

Completed

Effects of the SGLT2-inhibitor Empagliflozin on Patients With Chronic SIADH - the SANDx Study (SANDx)

Hyponatremia | SIAD - Syndrome of Inappropriate Antidiuresis

Switzerland
University Hospital, Basel, Switzerland

Recruiting

Effects of Intravenous [Pyr1]Apelin-13 on Healthy Volunteers With Artificially Induced SIAD (ESCAPE)

Hyponatremia | SIAD - Syndrome of Inappropriate Antidiuresis

Switzerland
Otsuka Pharmaceutical Europe Ltd

Completed

An Observational Study to Describe the Adherence to the SEOM Algorithm for the Treatment of Hyponatraemia in Spain (ALGA)

Hyponatremia | Syndrome of Inappropriate ADH (SIADH) Secretion

Spain
Otsuka Pharmaceutical Europe Ltd

Completed

An Observational Study on Real-world Use and Outcomes of Patients Treated With Tolvaptan for Hyponatraemia Due to SIADH (SAMPLE)

Hyponatremia | Syndrome of Inappropriate ADH (SIADH) Secretion

Germany, Spain
Thomas Jefferson University

Unknown

Safety and Feasibility of Hypertonic Saline Solution After Aneurysmal Subarachnoid Hemorrhage: (HS3)

Subarachnoid Hemorrhage | Hyponatremia | Cerebral Vasospasm

United States
Otsuka Pharmaceutical Europe Ltd

Completed

An Observational Study Measuring Outcomes in Cancer Patients Treated for Moderate to Severe Hyponatremia in Italy (ASSERT)

Cancer | Hyponatremia | Syndrome of Inappropriate ADH (SIADH) Secretion

Italy
Ankara University

Completed

Hyponatremia and Hypoalbuminemia is Morbimortality Predictors in Coronary Artery Bypass Graft Surgery

Coronary Artery Disease | Hyponatremia | Hypoalbuminemia
Hospital Nacional Profesor Alejandro Posadas

Completed

HYPONATREMIA IN COVID-19 PATIENTS

Covid19 | Corona Virus Infection | Hyponatremia

Argentina
Ankara City Hospital Bilkent

Completed

Effect of Hyponatremia in Small Cell Lung Cancer

Small Cell Lung Cancer
Sanofi

Terminated

A Phase III Study Evaluating the Efficacy and Safety of Satavaptan Versus Placebo in Patients With Dilutional Hyponatremia (AQUARIST1)

Hyponatremia | Inappropriate ADH Syndrome

United States
University Hospital, Basel, Switzerland
Centre Hospitalier Universitaire Vaudois; Luzerner Kantonsspital

Recruiting

Effects of the SGLT2 Inhibitor Empagliflozin in Patients With Euvolemic and Hypervolemic Hyponatremia (EMPOWER)

Liver Failure | Hyponatremia | Kidney Failure | SIADH

Switzerland
Medical University of Lodz

Completed

Serum Copeptin as a Predictor of the Risk of Hyponatremia After Transurethral Prostatectomy

Benign Prostatic Hyperplasia

Poland
Hunter Holmes Mcguire Veteran Affairs Medical Center
Otsuka America Pharmaceutical

Completed

Effect of Tolvaptan on Cognitive Function in Cirrhosis

Hepatic Encephalopathy | Cirrhosis | Hyponatremia

United States
Assiut University

Not yet recruiting

Relation Between COVID-19 Pts and Hyponatremia in Adreno Ortical Insufficient Patients.

COVID-19
European Georges Pompidou Hospital

Completed

Water Load Test Value for Hyponatremia (WATERLINE)

Hyponatremia | SIAD - Syndrome of Inappropriate Antidiuresis

France
University of Erlangen-Nürnberg Medical School

Completed

Tolvaptan Versus Fluid Restriction in SIADH

Hyponatremia | Pituitary | Syndrome of Inappropriate ADH (SIADH) Secretion
Otsuka Pharmaceutical Development & Commercialization...
Otsuka Pharmaceutical Co., Ltd.

Completed

"SALT-2 Trial" Study of Ascending Levels of Tolvaptan in Hyponatremia

Hyponatremia | Inappropriate ADH Syndrome | Water Intoxication | Water-electrolyte Imbalance

Germany
Sanofi

Completed

Safety and Efficacy of SR121463B in Patients With Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH Safety)

Hyponatremia | Inappropriate ADH Syndrome

United States, France, Brazil, Russian Federation, Australia, Germany, Switzerland, Belgium, Hungary, Hong Kong, Canada
University Hospital, Montpellier

Recruiting

Prevalence, Severity, Risk Factors, and Prognostic Value of Hyponatremia in Patients With Traumatic Brain Injury (WATERWAR)

Traumatic Brain Injury

France
Sanofi

Completed

Efficacy and Safety of SR121463B in Patients With Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH)

Hyponatremia | Inappropriate ADH Syndrome

United States, Canada, Brazil, Germany, Netherlands, Portugal, Spain, Belgium, Croatia, Hungary, Hong Kong
Otsuka Pharmaceutical Development & Commercialization...
Otsuka Pharmaceutical Co., Ltd.

Completed

"SALT Trial" Study of Ascending Levels of Tolvaptan in Hyponatremia

Inappropriate ADH Syndrome | Water Intoxication | Hyponatremias | Water-Electrolyte Imbalances

United States
University of Cologne

Recruiting

Regulation of Extracellular Sodium in End Stage Renal Disease Upon Volume and Electrolyte Challenges (RESERVE)

Hyponatremia

Germany
St. Joseph's Hospital and Medical Center, Phoenix
Barrow Neurological Institute; Barrow Brain and Spine

Completed

Post-Operative Water Load Following Transsphenoidal Pituitary Surgery

Pituitary Adenoma | Hyponatremia

United States
Sanofi

Completed

Efficacy of SR121463B in Patients With Syndrome of Inappropriate Antidiuretic Hormone Secretion

Hyponatremia | Syndrome of Inappropriate ADH (SIADH) Secretion

France, Germany, Belgium, Hungary
Otsuka Pharmaceutical Co., Ltd.

Completed

A Multicenter Trial to Investigate the Efficacy and Safety of Tolvaptan in Patients With Hyponatremia in SIADH

Syndrome of Inappropriate Antidiuretic Hormone Secretion

Japan
Hospital Clinic of Barcelona
Hospital Universitari de Bellvitge; Maternal-Infantil Vall d´Hebron Hospital

Completed

Effect of Midodrine and Albumine in the Prevention of Complications in Cirrhotic Patients Awaiting Liver Transplantation (MACHT)

Sepsis | Hepatic Encephalopathy | Renal Failure | Hyponatremia | Gastrointestinal Bleeding

Spain
Otsuka Pharmaceutical Co., Ltd.

Recruiting

Samsca Post-marketing General Drug Use-results Survey in Patients With Hyponatremia in SIADH

Antidiuretic Hormone, Inappropriate Secretion

Japan

Clinical Trials on Hyponatrémie

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