Clinical Trials on Hypotension and Shock in United Kingdom

Total 161079 results

University of Illinois at Chicago
La Jolla Pharmaceutical Company

Completed

Angiotensin II in the Perioperative Management of Hypotension in Kidney Transplant Recipients

Shock | Kidney Transplant; Complications | Hypotension and Shock | Intraoperative Hypotension | Shock, Surgical | Postoperative Hypotension

United States
Nemours Children's Clinic

Completed

ClearSight Validation in Pediatrics

Shock | Hypotension and Shock

United States
La Jolla Pharmaceutical Company

Completed

A Study of LJPC-501 in Pediatric Patients With Hypotension

Sepsis | Catecholamine-resistant Hypotension (CRH) | Distributive Shock | High Output Shock

United States
La Jolla Pharmaceutical Company

Completed

A Phase 3 Study of LJPC-501 in Patients With Catecholamine-Resistant Hypotension (ATHOS-3)

Sepsis | Catecholamine-resistant Hypotension (CRH) | Distributive Shock | High Output Shock

United States, Canada, Belgium, Australia, United Kingdom, Finland, New Zealand, France, Switzerland, Germany
King's College Hospital NHS Trust
University Hospital Birmingham

Completed

An Observational Pilot Study of the Effects of Traumatic Haemorrhagic Shock and Resuscitation on the Microcirculation (MICROSHOCK)

Traumatic Haemorrhagic Shock

United Kingdom
Manchester University NHS Foundation Trust
University of Manchester

Recruiting

Strong Albumin Solutions in Patients With Septic Shock (SWIPE2)

Sepsis | Septic Shock | Shock, Toxic

United Kingdom
King's College London

Unknown

Microcirculatory Guided Goal Directed Fluid Therapy in Septic Shock; a Feasibility Study (MICRORESUS)

Septic Shock

United Kingdom
Nottingham University Hospitals NHS Trust

Unknown

G- Forces On Retrieved ChildrEn Pilot Study (G-FORCE)

Physiological Shock

United Kingdom
Barts & The London NHS Trust
University of Oxford

Recruiting

Genomic Determinants of Outcome in Cardiogenic Shock (Goldilocs)

Cardiogenic Shock

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust

Unknown

Evaluation of Speckle Tracking Parameters as Predictors of Successful VA SPECKLE ECMO (SPECKLE-ECMO)

Cardiogenic Shock

United Kingdom
Teesside University

Unknown

Inferior Vena Cava Collapsibility Index in Severe Sepsis

Sepsis | Septic Shock | Severe Sepsis

United Kingdom
University of Edinburgh
Becton, Dickinson and Company; Technology Strategy Board, United Kingdom

Completed

Immune Failure in Critical Therapy (INFECT) Study (INFECT)

Sepsis | Septic Shock

United Kingdom
Mayo Clinic

Completed

Physiological Validation of Current Machine Learning Models for Hemodynamic Instability in Humans

Hypotension and Shock

United States
George Washington University

Completed

Intravenous AII for the Treatment of Severe Hypotension in High Output Shock: A Pilot Study (ATHOS)

Septic Shock

United States
Andrew Tomas Reisner
Nihon Kohden

Active, not recruiting

BP Management System User Acceptance Testing

Hypotension and Shock

United States
University of Minnesota

Recruiting

Non-Invasive Cardiac Output Monitor (NICOM) for Goal-directed Fluid Resuscitation for Inpatients With Hypotension and/or Septic Shock

Sepsis | Septic Shock | Hypotension

United States
Mayo Clinic

Completed

Measurement of Hemodynamic Responses to Lower Body Negative Pressure (LBNP)

Hypotension and Shock

United States
King's College London
Royal Centre for Defence Medicine

Unknown

Macro and Micro Haemodynamic Responses to Shock in the Renal and Systemic - MICROSHOCK - RENAL

Septic Shock | Acute Kidney Injury

United Kingdom
NHS Greater Glasgow and Clyde

Completed

The Use of LiDCOplus in Fluid Resuscitation Decision-Making

Shock

United Kingdom
Vanderbilt University Medical Center
Baxter Healthcare Corporation

Terminated

Peripheral Venous Analysis (PIVA) for Predicting Volume Responsiveness and Fluid Status (PIVA)

Systemic Inflammatory Response Syndrome | Atrial Fibrillation | Hypotension and Shock | Distributive Shock | Decompensated Congestive Heart Failure | High Risk Non-cardiac Surgery

United States
Vivacelle Bio

Active, not recruiting

VBI-S for the Treatment of Hypotension in Hypovolemic Septic Shock Patients

Sepsis | Septic Shock | Hypovolemia

United States
University of Leicester
University Hospitals, Leicester; The Royal College of Anaesthetists

Completed

Release of Nociceptin From Granulocytes in Sepsis

Sepsis | Septic Shock | Severe Sepsis | Sepsis Syndrome

United Kingdom
King's College Hospital NHS Trust
European Society of Intensive Care Medicine; Royal Centre for Defence Medicine

Not yet recruiting

The Effect of Vasopressor Therapy on Renal Perfusion in Septic Shock (REPERFUSE)

Septic Shock | Acute Kidney Injury

United Kingdom
Wake Forest University Health Sciences
University of North Carolina, Charlotte

Completed

Systolic Blood Pressure Measurement in Critically-ill Patients

Shock | Hypotension

United States
Beth Israel Deaconess Medical Center
American Heart Association

Terminated

Esmolol to Treat the Hemodynamic Effects of Septic Shock

Septic Shock | Tachycardia | Hypotension

United States
University College London Hospitals
Wellcome Trust; Department of Health, United Kingdom

Unknown

Surrogate of Adequate Perfusion: Bladder Tissue Oxygen Monitoring (SoAP-BOx)

Sepsis | Shock | Surgery

United Kingdom
Cardiff University

Completed

Diagnostic Investigation and Prediction of Shock (DiPS)

Shock

United Kingdom
Ivor Douglas
Baxter Healthcare Corporation; Oregon Health and Science University

Completed

Evaluation of Fluid Volume in Patients With Refractory Hypotension (Fresh-ER) (Fresh-ER)

Undifferentated Shock

United States
Brighton and Sussex University Hospitals NHS Trust
European Union

Completed

NeoAdapt 2: An Observational Study Investigating Novel Biomarkers in the Evaluation and Treatment of Neonatal Circulatory Insufficiency

Circulatory Failure

United Kingdom
Francois Lamontagne
Canadian Institutes of Health Research (CIHR); Fonds de la Recherche en Santé... and other collaborators

Completed

Optimal VAsopressor titraTION Pilot Randomized Controlled Trial (OVATION)

Shock | Hypotension

Canada, United States
Erasmus Medical Center

Completed

PULsecath mechanicaL Support Evaluation (PULSE)

Coronary Artery Disease | Heart Failure | Cardiogenic Shock

France, Netherlands, United Kingdom
Odense University Hospital
Charite University, Berlin, Germany; Hannover Medical School; Aarhus University... and other collaborators

Completed

Danish Cardiogenic Shock Trial (DanShock)

Acute Myocardial Infarction | Cardiogenic Shock Acute

Germany, Denmark, United Kingdom
Imperial College London

Terminated

Study of Albumin to Reduce Inflammation Following Surgery

Systemic Inflammatory Response Syndrome | Cardiopulmonary Bypass

United Kingdom
Xim Limited
Portsmouth Hospitals NHS Trust; Mind Over Matter Medtech Ltd

Completed

The VISION-Acute Study

Hypertension | Hypoxia | Hypotension

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
King's College Hospital NHS Trust

Recruiting

Endothelial Function, Inflammation and Organ Dysfunction in COVID-19

Shock | COVID

United Kingdom
Sangart

Completed

Phase IIa Study of MP4OX in Traumatic Hemorrhagic Shock Patients

Shock, Hemorrhagic | Acidosis, Lactic | Shock, Traumatic

France, United Kingdom, South Africa, Germany
Brighton and Sussex University Hospitals NHS Trust
European Union

Completed

NeoAdapt 1: A Study of Circulatory Adaptation of Newborn Infants After Birth

Circulatory Failure in Newborn Infants

United Kingdom
University of Leicester
Zimmer Biomet; British Heart Foundation; National Health Service, United Kingdom

Withdrawn

Red Cell Rejuvenation for the Attenuation of Transfusion Associated Organ Injury in Cardiac Surgery

Sepsis | Inflammation | Organ Failure, Multiple

United Kingdom
University College, London
King's College London; University of Nottingham; Imperial College London

Completed

Musculoskeletal Ultrasound Study in Critical Care: Longitudinal Evaluation (MUSCLE)

Critical Illness | Septic Shock | Trauma | Organ Failure

United Kingdom
Wright State University

Recruiting

Using Vasopressor Medication to Support Blood Pressure During Intubation Procedure (RAPID PRESS)

Respiratory Failure | Intubation Complication | Anesthesia Intubation Complication | Hypotension and Shock | Hypotension on Induction

United States
Imperial College London

Recruiting

Mechanisms of Multi-organ Failure in COVID-19

COVID

United Kingdom
Anders Perner
Rigshospitalet, Denmark; Scandinavian Critical Care Trials Group; Centre for...

Active, not recruiting

The Conservative vs. Liberal Approach to Fluid Therapy of Septic Shock in Intensive Care Trial (CLASSIC)

Septic Shock

Sweden, Denmark, Belgium, Czechia, Italy, Norway, Switzerland, United Kingdom
Directed Systems Limited
University Hospital Birmingham NHS Foundation Trust; Innovate UK

Completed

Hypotension Decision Assist - Use, Safety and Efficacy (HDA-USE)

Intraoperative Hypotension

United Kingdom
San Diego Veterans Healthcare System
Inflammagen/Leading Ventures

Terminated

Single Dose Enteral Tranexamic Acid in Critically Ill Patients

Sepsis | Shock | Critical Illness | Hypotension

United States
University of Dundee
British Geriatrics Society

Completed

Vitamin K Status and Markers of Vascular Function in Patients With and Without Postural Hypotension (VITKOH)

Orthostatic Hypotension

United Kingdom
Massachusetts General Hospital
Beth Israel Deaconess Medical Center; Boston Medical Center; Tufts Medical Center and other collaborators

Recruiting

Blood Transfusion by Boston MedFlight Registry

Hemorrhagic Shock

United States
Jason Sperry
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

Pragmatic Prehospital Group O Whole Blood Early Resuscitation Trial (PPOWER)

Hemorrhagic Shock

United States
University of Texas Southwestern Medical Center
University of Washington; Resuscitation Outcomes Consortium

Completed

Resuscitative Endocrinology: Single-dose Clinical Uses for Estrogen-Traumatic Hemorrhagic Shock (RESCUE - Shock) (RESCUE-Shock)

Hemorrhagic Shock

United States
Arsenal Medical, Inc.

Not yet recruiting

REVIVE: Reducing Exsanguination Via In-Vivo Expandable Foam (REVIVE)

Trauma | Hemorrhagic Shock | Exsanguinating Hemorrhage | Shock; Traumatic

United States
National Institute of Allergy and Infectious Diseases...

Completed

Phase I STEBVax in Healthy Adults

Toxic Shock Syndrome Staphylococcal

United States

Clinical Trials on Hypotension and Shock in United Kingdom

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Dominican Republic

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations