Clinical Trials on Hypovolemic Shock

Total 1931 results

Johann Wolfgang Goethe University Hospital

Unknown

Measurement of Fibrinogen in Patients With Systemic Inflammatory Response Syndrome (SIRS), Sepsis or Chronicle Liver Disease on Intensive Care Units (ICU)

Sepsis | Liver Disease | SIRS

Germany
Rigshospitalet, Denmark

Active, not recruiting

GLP-1 and Hyperoxia for Organ Protection in Heart Surgery (GLORIOUS)

Stroke | Coronary Disease | Brain Injury | Aortic Valve Disease | Renal Failure | Shock, Cardiogenic

Denmark
St Vincent's Hospital, Sydney

Completed

Blood Management During ECMO for Cardiac Support (OBLEX)

Hemorrhage | Embolism | Venous Thrombosis | Arrhythmias, Cardiac | Shock, Cardiogenic | Blood Transfusion | Death, Sudden, Cardiac | Disseminated Intravascular Coagulation | HEART ARREST

Australia
Fujian Medical University

Not yet recruiting

Exosome of Mesenchymal Stem Cells for Multiple Organ Dysfuntion Syndrome After Surgical Repaire of Acute Type A Aortic Dissection

Multiple Organ Failure
Radboud University Medical Center
Exponential Biotherapies Inc.

Unknown

Immunomodulation of EA-230 Following On-pump Coronary Artery Bypass Grafting (CABG) (EASI)

Systemic Inflammatory Response Syndrome | Coronary Artery Bypass Grafting

Netherlands
UMC Utrecht
European Association of Cardiothoracic Anaesthesiologists

Completed

Inflammatory Response During Anesthesia and Surgery (IRAS)

Myocardial Ischemia | Systemic Inflammatory Response Syndrome

Netherlands
University of Aarhus

Completed

Effects of Free Fatty Acids and 3-hydroxybutyrate on Protein, Glucose, Lipid Metabolism and Intracellular Signals.

Systemic Inflammatory Response Syndrome

Denmark
Université de Sherbrooke
Centre de recherche du CHUS

Recruiting

EPI-STORM: Cytokine Storm in Organ Donors (EPI-STORM)

Liver Transplantation | Kidney Transplantation | Organ Donation | Graft Dysfunction

Canada
Incyte Corporation

Completed

A Study of Itacitinib for the Prevention of Cytokine Release Syndrome Induced by Immune Effector Cell Therapy

Cytokine Release Syndrome

United States
Applied Science Private University

Completed

The Effect of Omega-3 on Selected Cytokines Involved in Cytokine Storm

Cytokine Storm | Cytokines

Jordan
Wake Forest University Health Sciences

Withdrawn

Presep and Vascath Interaction Study

Sepsis | Shock | Renal Dialysis | Hemodynamics

United States
Töölö Hospital
Turku University Hospital; Tampere University Hospital; Jyväskylä Central Hospital and other collaborators

Recruiting

Proximal Row Carpectomy vs Four-corner Fusion for Osteoarthritis of the Wrist (PROOF)

Wrist Osteoarthritis | Scapholunate Advanced Collapse

Finland
Massachusetts General Hospital

Withdrawn

Vitamin D Status in Patients With Severe Sepsis (ViDISS)

Sepsis | Severe Sepsis | Multi Organ Failure | End Organ Damage

United States
Maimónides Biomedical Research Institute of Córdoba

Unknown

Clinical Trial for Valuation of the Effectiveness of Lactoferrine in the Prevention of Sepsis in New Premature Born. Bimonitorization of the Antinflammatory Mechanisms, Antioxidants and the Intestinal Microbiote. (LACTOPREM)

SEPSIS SYNDROME

Spain
Aretaieion University Hospital

Completed

Blood Transfusions and Immune Response

Surgery | Cytokine Storm | Infection After Transfusion | Transfusion-related Immunomodulation Reaction

Greece
Ruhr University of Bochum

Completed

Surgical and Medical Emergencies on Board of European Aircraft Carriers

Diarrhea | Chest Pain | Circulatory Collapse

Germany
UMC Utrecht

Completed

Dexamethasone for Cardiac Surgery Trial

Systemic Inflammatory Response Syndrome | Postoperative Complications | Cardiac Diseases

Netherlands
Federal University of São Paulo

Completed

Keratinocyte Growth Factor and Cytokines in Burns.

Inflammation | Burns | Cytokine Storm | Growth Factors, Combined Defect of

Brazil
Azhar University

Recruiting

Use of Renin Versus Lactic Acid as Tissue Perfusion Biomarkers for Mortality Prediction in Hypotensive Critically Ill Patients

Sepsis | Critical Illness | Critically Ill | Hypotensive | Obstructive Shock

Egypt
Revimmune
Washington University School of Medicine; Vanderbilt University School of Medicine

Completed

A Study of IL-7 to Restore Absolute Lymphocyte Counts in Sepsis Patients (IRIS-7-B)

Severe Sepsis With Septic Shock

United States
Centre Hospitalier Departemental Vendee
Institut National de la Santé Et de la Recherche Médicale, France; Ministry... and other collaborators

Terminated

Impact of Early Enteral vs. Parenteral Nutrition on Mortality in Patients Requiring Mechanical Ventilation and Catecholamines (NUTRIREA2)

Shock | Acute Respiratory Failure

France
Althaia Xarxa Assistencial Universitària de Manresa

Terminated

Cerebral Autoregulation in Non Neurological Critical Patients.

Systemic Inflammatory Response Syndrome | Critical Illness | Complication of Ventilation Therapy | Failed Moderate Sedation During Procedure, Sequela

Spain
Medical University of Warsaw

Not yet recruiting

Polish Nationwide Register of Hospitalized Patients in Cardiac Intensive Care Units (POL-CICU)

Stroke | Infections | Shock | Death | Multiple Organ Failure | Treatment Complication | Cardiac Intensive Care Unit
Poitiers University Hospital

Completed

Fluid Responsiveness Evaluation in Patients With Acute Circulatory Failure and Arrhythmia With Atrial Fibrillation: Indice Delta ITV / Delta RR

Arrhythmia Atrial

France
Centre Hospitalier Departemental Vendee
Institut National de la Santé Et de la Recherche Médicale, France; Ministry... and other collaborators

Terminated

Impact of Early Enteral vs. Parenteral Nutrition on Preservation of Gut Mucosa Integrity in Patients Requiring Mechanical Ventilation and Catecholamine

Shock | Acute Respiratory Failure

France
Mahidol University

Completed

Major Allergen in Wheat Anaphylaxis in Thai Population

Wheat Allergy | Anaphylaxis Food | Anaphylaxis Exercise

Thailand
Axis Shield Diagnostics Ltd
Baylor College of Medicine; Vanderbilt University Medical Center; York Hospitals and other collaborators

Unknown

Assessment of Heparin Binding Protein for the Prediction of Severe Sepsis

Sepsis | Septic Shock | Sepsis With Acute Organ Dysfunction

United States
University Hospital, Lille

Completed

Respiratory Variations For Predicting Fluid Responsiveness 2 (ReVaPreF2)

Sepsis | Circulatory Failure | Respiratory Physiological Phenomena

France
Lawson Health Research Institute
Western University, Canada; London Health Sciences Centre; Western University

Not yet recruiting

Early Severe Illness TrAnslational BioLogy InformaticS in Humans (ESTABLISH)

Sepsis | Inflammation | Critical Illness | Shock, Septic | ARDS | SIRS | Ventilator Associated Pneumonia | Neurocognitive Dysfunction | Immune Suppression

Canada
CytoAgents, Inc.
TFS HealthScience

Recruiting

Study of CTO1681 for the Prevention and Treatment of CRS in DLBCL Patients Receiving CAR T-Cell Therapy

Cytokine Release Syndrome

United States
Azienda Usl di Bologna

Recruiting

Prehospital Management of Hypotensive Trauma in HEMS (SPITFIRE)

Wounds and Injuries | Emergencies | Critical Care | Hypotension and Shock

Italy
Albert Einstein College of Medicine
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Prevention of Severe Acute Respiratory Failure in Patients With PROOFCheck (PROOFcheck)

Respiratory Failure | Multiple Organ Failure

United States
UMC Utrecht

Terminated

The Role of Post-traumatic Inhibition of the Innate and Adaptive Immune System in the Development of Infectious Complications in Severely Injured Patients (POSEIDON)

Sepsis | Multiple Trauma | Innate Immune Response | Multiple Organ Dysfunction Syndrome | Disorder of Neutrophils

Netherlands
University Hospital, Lille

Completed

Respiratory Variations for Predicting Fluid Responsiveness (ReVaPreF)

Sepsis | Circulatory Failure | Respiratory Physiological Phenomena

France
Hospices Civils de Lyon

Not yet recruiting

Cardiac Responsiveness Assessment by CO2 (CRAC)

VCO2 Variation in Intensive Care as a Marker of Fluid Responsiveness | Cardiac Index Variation Transpulmonary Thermodilution in Patients on Controlled Ventilation With Shock

France
National Institute of Allergy and Infectious Diseases...

Recruiting

Cause of Unexplained Anaphylaxis

Idiopathic Anaphylaxis | Drug Anaphylaxis | Venom Anaphylaxis | Food Anaphylaxis

United States
Iuliu Hatieganu University of Medicine and Pharmacy

Completed

Interventions Meant to Improve the Outcome of Critical Care Patients in the ED

Sepsis Syndrome | Emergency Department | Biomarker

Romania
Temple University

Withdrawn

RepurpoSing Old Drugs TO SuppRess a Modern Threat: COVID-19 STORM (STORM)

SARS-CoV-2 | Cytokine Storm

United States
MicroPort CRM

Active, not recruiting

Observational Study on Inappropriate Therapies (OSIRIS)

Inappropriate Shocks From Implanted Defibrillator | ICD Replacement or Upgrade

Netherlands, United States, France, Spain, Belgium, Switzerland, Italy, United Kingdom, Germany, Austria, Portugal
National Institute of Allergy and Infectious Diseases...

Completed

Pleconaril Enteroviral Sepsis Syndrome

Enterovirus Infection

United States, Canada
Hakan Küçükkepeci

Enrolling by invitation

EFFECTS OF EXTRACORPOREAL CYTOKINE ELIMINATION ON HEMODYNAMIA AND MORTALITY IN CRITICAL PATIENTS

Cytokine Hemadsorption Therapy in Critically Ill Patients Who Have no Microbiological Findings and Develop Vasoplegic Shock

Turkey
Applied Science Private University

Completed

The Effect of D3 on Selected Cytokines Involved in Cytokine Storm in the Covid-19 Uninfected Jordanian People

Cytokine Storm

Jordan
Wuhan Asia Heart Hospital

Completed

Evaluation of Soluble ST2 in Patients Receiving Primary PCI With ST-elevation Myocardial Infarction

Myocardial Infarction | Shock

China
University Hospital Schleswig-Holstein

Completed

Influence of Fluid Challenge on End-Expiratory Lung Impedance in Mechanically Ventilated Patients Monitored With Electrical Impedance Tomography

Respiratory Failure | Fluid Overload | Circulatory Failure | Fluid Responsiveness

Germany
Boehringer Ingelheim

Completed

Post-authorization Safety Study in Type 2 Diabetic Patients in Saudi Arabia Treated With Empagliflozin to Assess the Incidence of Ketoacidosis, Severe Complications of Urinary Tract Infection, Volume Depletion, and Dehydration

Diabetes Mellitus, Type 2

Saudi Arabia
University of Turin, Italy
Istituto Di Ricerche Farmacologiche Mario Negri

Not yet recruiting

Preventing Cardiovascular Collapse With Vasopressors During Tracheal Intubation (PREVENTION)

Critical Illness | Respiratory Failure

France, Ireland, Italy
Regional Hospital Liberec
Charles University, Czech Republic; University of Sao Paulo; Technology Agency...

Recruiting

The Effect of Lateral Tilt on Ventilation Distribution in Lungs Assessed by Electrical Impedance Tomography (N-LAT-EIT)

Lung Collapse

Czechia
Maurizio Eugenio Landolina

Recruiting

Arrhythmias Detection in a Real World Population (RHYTHM DETECT)

Appropriate and Inappropriate Shock Therapy With ICD | Arrhythmias Detection

Italy
Ain Shams University

Completed

Interleukin-34 in Stage I and II Periodontitis

Cytokine Storm

Egypt
University of Rostock

Completed

Impact of Human Blood Serum From Critically Ill Patients on Human Colon Neuronal Networks.

Critical Illness | Multiple Organ Failure | Myopathy | Polyneuropathy

Germany

Clinical Trials on Hypovolemic Shock

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