Clinical Trials on Idiosyncratic Drug Effect

Total 5409 results

Fundación Pública Andaluza para la Investigación...

Not yet recruiting

Proof-of-concept to Evaluate the Efficacy and Safety of Prednisone in Idiosyncratic Hepatotoxicity (DILICORT)

Prednisone | Hepatotoxicity | Idiosyncratic Drug Effect
Albert Einstein College of Medicine

Completed

Studies of Sulfur Metabolism in Humans

Metabolic Side Effects of Drugs

United States
University of Copenhagen
Carlsberg Foundation

Completed

Metabolic Imprints of Alcoholic Beverages (MetAl)

Metabolic Side Effects of Drugs and Substances

Denmark
Walter Reed National Military Medical Center
United States Department of Defense; General Services Administration (GSA)

Active, not recruiting

Reducing Concurrent Opioid-Benzodiazepine Prescriptions

Adverse Drug Effect of Opioids | Adverse Drug Effect of Benzodiazepines

United States
Companion Dx Reference Lab, LLC

Unknown

Pharmacogenomics Registry to Assess Clinical Utility (PREACT)

Drug Side Effects
Wolfson Medical Center

Completed

The Use of STOPP/START Criteria for Medication Intervention Among Elderly Population Living in a Geriatric Hospital (STOPP)

Adverse Drug Effects

Israel
Indiana University
National Institute of General Medical Sciences (NIGMS)

Completed

Bupropion Stereoselective Disposition and CYP2D6-mediated Drug Interactions in Healthy Volunteers

Adverse Effect of Drug Therapy Metabolism Medications (Diagnosis)

United States
First Affiliated Hospital Xi'an Jiaotong University

Not yet recruiting

Remimazolam Improves the Safety in Elderly Patients Undergoing Gastrointestinal Endoscopy

Recovery | Drug Effect | Safety | Psychotropic Drugs | Anesthetics, Intravenous | Anesthetics

China
Olympic Seafood AS

Completed

Safety and Tolerability of Krill Powder Supplement in Slightly Overweight People With Moderately Elevated Blood Pressure

Adverse Drug Event | Side Effects of Drugs

Finland
Sun Yat-sen University

Not yet recruiting

the SDMEAI Study: a Multi-center Epidemiological Study

Artificial Intelligence | Eye Involvement of Systemic Diseaes | Adverse Drug Effect on Eye
Companion Dx Reference Lab, LLC

Unknown

Utility of PharmacoGenomics for Reducing Adverse Drug Effects (UPGRADE)

Genetics of Drug Metabolism

United States
Jørgen Bjerggaard Jensen
Odense University Hospital; Karolinska University Hospital; Zealand University... and other collaborators

Recruiting

NORTH-REG Dwell-Time Study

Side Effect of Drug

Denmark, Sweden, Iceland
Lobe Sciences Ltd.
Pharmaceutical Research Unit, Jordan

Completed

Evaluation of Safety, Rate and Extent of Absorption of Psilocin Mucate (Psilocin-1)

Side Effect of Drug

Jordan
Assiut University

Completed

Efficacy of Repetitive Trans-spinal Magnetic Stimulation on Axial Motor Symptoms in PD (rTSMS)

Adverse Effect of Drug Therapy Levodopa

Egypt
Oslo University Hospital

Active, not recruiting

Effects of Switching From Racemic Methadone to R-methadone on QTc Intervals (MePhaCard)

Drug Effect | Adverse Drug Effect | Heart Arrhythmia

Norway
Saint-Joseph University

Completed

Evaluation of Efficacy and Safety of Subcutaneous Acetaminophen (APAPSubQ)

Pain | Fever | Drug Effect | Drug Reaction

Lebanon
Fundação Bahiana de Infectologia
Hospital de Clinicas de Porto Alegre; Universidade Federal do Rio Grande do... and other collaborators

Recruiting

Dolutegravir and Clinical Outcomes Among ART-recipients in Brazil (CODE)

HIV Infections | Clinical Outcomes | Adverse Drug Event | Effect of Drugs

Brazil
Mayo Clinic

Not yet recruiting

Pharmacogenetic Panel to Prevent Adverse Drug Reactions in Daily Primary Care Practice: (PREPARE-Mayo)

Side Effect of Drug | Pharmacogenomic Drug Interaction | Drug Metabolism, Poor, CYP2D6-Related | Ineffective Drug Action | Drug Metabolism, Poor, CYP2C19-Related

United States
Prof Gérard WAEBER
Centre Hospitalier Universitaire Vaudois; University of Lausanne; Center for...

Terminated

A Double Blind Randomised Placebo-controlled Trial to Assess the Role of Iron Repletion in Glucose Homeostasis. (DIAFER)

Iron-deficiency | Safety Issues | Metabolic Disorder, Glucose | Iron Toxicity | Glucose Metabolism Disorders (Including Diabetes Mellitus) | Metabolic Side Effects of Drugs

Switzerland
Glostrup University Hospital, Copenhagen

Completed

Pupillary Response After Glaucoma Medication (pupil)

Drug Effect (Glaucoma Drugs)

Denmark
Seoul National University Hospital
Asan Medical Center; Myongji Hospital

Unknown

The Effect of Ondansetron During Intramuscular Ketamine Use in Children: A Trial in Emergency Department

Side Effect of Drug | Sedation and Analgesia

Korea, Republic of
St. Antonius Hospital
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

Completed

Pharmacokinetics of Morphine and Oxycodone in Frail Elderly Undergoing Cardiac Surgery

Postoperative Pain | Opioid Use | Side Effect of Drug

Netherlands
Guangdong Provincial Hospital of Traditional Chinese...
Peking Union Medical College Hospital

Not yet recruiting

Efficacy and Safety of Expanded UCMSCs On Patients With Moderate to Severe Psoriasis (UCMSCs)

Psoriasis | Drug Effect | Drug Toxicity | Mesenchymal Stromal Cells

China
Guangdong Provincial Hospital of Traditional Chinese...

Completed

Efficacy and Safety of AD-MSCs Plus Calpocitriol Ointment in Patients With Moderate to Severe Psoriasis

Psoriasis | Drug Effect | Drug Toxicity | Mesenchymal Stromal Cells

China
Guangdong Provincial Hospital of Traditional Chinese...

Completed

Safety and Efficacy of Expanded Allogeneic AD-MSCs in Patients With Moderate to Severe Psoriasis (ADMSP)

Psoriasis | Drug Effect | Drug Toxicity | Mesenchymal Stromal Cells

China
Guangdong Provincial Hospital of Traditional Chinese...

Completed

Efficacy and Safety of AD-MSCs Plus Calpocitriol Ointment and PSORI-CM01 Granule in Psoriasis Patients

Psoriasis | Drug Effect | Drug Toxicity | Mesenchymal Stromal Cells

China
Suez Canal University

Recruiting

Pulpotomy Medications in Primary Teeth

Drug Effect

Egypt
Boston Children's Hospital

Recruiting

Pharmacokinetics of Bivalirudin for Pediatric Anticoagulation

Drug Effect

United States
Boston Children's Hospital

Terminated

Pharmacokinetics of Antibiotics During Extracorporeal Membrane Oxygenation (ECMO) Support

Drug Effect

United States
Suez Canal University

Completed

Evaluation of Antibacterial Effect of Allium Sativum, Calcium Hydroxide and Their Combination in Infected Mature Teeth (Garlic)

Drug Effect

Egypt
Johns Hopkins University
National Institute on Drug Abuse (NIDA)

Completed

Effects of Salvinorin A on Brain Function

Drug Effect

United States
Services Institute of Medical Sciences, Pakistan

Unknown

Comparision of Different Doses of Dexmedetomidine With Low Dose Bupivacaine in Selective Spinal Anesthesia.

Drug Effect

Pakistan
NHS Greater Glasgow and Clyde
Public Health Scotland

Recruiting

ASSIST: A Surveillance Study of Illicit Substance Toxicity (ASSIST)

Drug Effect | Drug Use | Drug Abuse | Drug Toxicity | Illicit Drug Use | Overdose, Drug | Illicit Drug Overdose | Illicit Drug Intoxication

United Kingdom
Boston Children's Hospital

Recruiting

Pharmacokinetics of Sedatives and Analgesics During Extracorporeal Membrane Oxygenation (ECMO) Support

Drug Effect

United States
Tanta University

Completed

Parathyroid Hormone Level and Growth in Pediatric Patients With ESRD on Regular Hemodialysis

Drug Effect

Egypt
Tongji Hospital

Completed

Remiazolam Combined With Esketamine in Painless Bidirectional Endoscopy in Children

Drug Effect

China
Guangdong Provincial People's Hospital

Unknown

PK/PD of the Sedatives, Analgesics and Antibiotics in Patients Receiving ECMO

Drug Effect

China
Oslo University Hospital

Recruiting

A Pilot Study for Optimizing Meropenem Administration in the ICU (MER6)

Drug Effect

Norway
General Hospital of Ningxia Medical University

Not yet recruiting

The Effect of Oxycodone Hydrochloride on CRBD After TURBT Under General Anesthesia

Effect of Drug | Adverse Effect of Opioids

China
Tongji Hospital
Xinxiang Central Hospital

Not yet recruiting

Effect of Equivalent Dose Sufentanil and Afentanil in Bronchoscopic Treatment (EOEDSAAIBT)

Effect of Drug

China
Tongji Hospital

Recruiting

ED90 of Remimazolam Anesthesia Induction in Drug-induced Sleep Endoscopy in Adults

Effect of Drug

China
Orinove, Inc.
Fosun Pharma

Active, not recruiting

Treatment of Patients With Advanced Solid Tumors With Oral Agent ORIN1001 and in Combination With Standard of Care.

Effect of Drug

China
Tanta University

Completed

The Effect of Opioid Free Anesthesia in Bariatric Surgeries (Opioidfree)

Adverse Effect of Drugs and Medicaments in Therapeutic Use | Adverse Effects in the Therapeutic Use of Anaesthetics

Egypt
Hematology Oncology Associates of Central New York

Not yet recruiting

PFA 100 Evaluation and Reference Interval HOACNY

Effect of Drug
Auburn University
VDF FutureCeuticals Inc.

Completed

Whole Coffee Cherry Study (WCCE)

Effect of Drug

United States
Sichuan Provincial People's Hospital

Completed

Effective Dose of Remimazolam Combined With Propofol in Painless Gastroscopy

Effect of Drug

China
Dow University of Health Sciences

Completed

Efficacy of Lidocaine and Xylometazoline Intranasal Spray in Anesthetizing Maxillary Teeth

Effect of Drug

Pakistan
Penn State University

Enrolling by invitation

Topical Cannabidiol Application and Skin Vascular Reactivity (cannabidiol)

Effect of Drug

United States
Dow University of Health Sciences

Completed

Emla Cream Versus Benzocaine on Analgesia

Effect of Drug

Pakistan
Assam Medical College

Completed

Comparison Between Bupivacaine and Ropivacaine in Patients Undergoing Forearm Surgeries Under Brachial Plexus Block

Effect of Drug

Clinical Trials on Idiosyncratic Drug Effect

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