Clinical Trials on Immune Tolerance/Drug Effects

Total 1657 results

Albert Einstein College of Medicine

Completed

Studies of Sulfur Metabolism in Humans

Metabolic Side Effects of Drugs

United States
University of Copenhagen
Carlsberg Foundation

Completed

Metabolic Imprints of Alcoholic Beverages (MetAl)

Metabolic Side Effects of Drugs and Substances

Denmark
Innovaderm Research Inc.

Completed

Effect of RANKL Inhibition on UV-induced Immunosuppression

Hypersensitivity, Delayed | Immunosuppression | Ultraviolet Rays | Immune Tolerance/Drug Effects

Canada
Companion Dx Reference Lab, LLC

Unknown

Pharmacogenomics Registry to Assess Clinical Utility (PREACT)

Drug Side Effects
Walter Reed National Military Medical Center
United States Department of Defense; General Services Administration (GSA)

Active, not recruiting

Reducing Concurrent Opioid-Benzodiazepine Prescriptions

Adverse Drug Effect of Opioids | Adverse Drug Effect of Benzodiazepines

United States
Wolfson Medical Center

Completed

The Use of STOPP/START Criteria for Medication Intervention Among Elderly Population Living in a Geriatric Hospital (STOPP)

Adverse Drug Effects

Israel
Xi'an Xintong Pharmaceutical Research Co.,Ltd.
The First Hospital of Jilin University

Recruiting

MB07133 for the Treatment of Patients With Unresectable Hepatocellular Carcinoma (MB07133)

Tolerance | Safety Issues | Effect of Drug

China
Olympic Seafood AS

Completed

Safety and Tolerability of Krill Powder Supplement in Slightly Overweight People With Moderately Elevated Blood Pressure

Adverse Drug Event | Side Effects of Drugs

Finland
Fundação Bahiana de Infectologia
Hospital de Clinicas de Porto Alegre; Universidade Federal do Rio Grande do... and other collaborators

Recruiting

Dolutegravir and Clinical Outcomes Among ART-recipients in Brazil (CODE)

HIV Infections | Clinical Outcomes | Adverse Drug Event | Effect of Drugs

Brazil
Indiana University
National Institute of General Medical Sciences (NIGMS)

Completed

Bupropion Stereoselective Disposition and CYP2D6-mediated Drug Interactions in Healthy Volunteers

Adverse Effect of Drug Therapy Metabolism Medications (Diagnosis)

United States
University Hospital, Geneva

Terminated

Evaluation of Pupillometry for cyp2d6 Phenotyping in Children Treated With Tramadol (PUPICYP)

Drug Effect | Drug Intolerance | Cytochrome P450 CYP2D6 Enzyme Deficiency

Switzerland
Sun Yat-sen University

Not yet recruiting

the SDMEAI Study: a Multi-center Epidemiological Study

Artificial Intelligence | Eye Involvement of Systemic Diseaes | Adverse Drug Effect on Eye
Jørgen Bjerggaard Jensen
Odense University Hospital; Karolinska University Hospital; Zealand University... and other collaborators

Recruiting

NORTH-REG Dwell-Time Study

Side Effect of Drug

Denmark, Sweden, Iceland
Companion Dx Reference Lab, LLC

Unknown

Utility of PharmacoGenomics for Reducing Adverse Drug Effects (UPGRADE)

Genetics of Drug Metabolism

United States
Lobe Sciences Ltd.
Pharmaceutical Research Unit, Jordan

Completed

Evaluation of Safety, Rate and Extent of Absorption of Psilocin Mucate (Psilocin-1)

Side Effect of Drug

Jordan
University Hospitals Cleveland Medical Center

Completed

Inpatient Penicillin Allergy Delabeling Study

Penicillin Allergy | Penicillin Sensitivity | Penicillin Reaction | Penicillin Intolerance

United States
Assiut University

Completed

Efficacy of Repetitive Trans-spinal Magnetic Stimulation on Axial Motor Symptoms in PD (rTSMS)

Adverse Effect of Drug Therapy Levodopa

Egypt
First Affiliated Hospital Xi'an Jiaotong University

Not yet recruiting

Remimazolam Improves the Safety in Elderly Patients Undergoing Gastrointestinal Endoscopy

Recovery | Drug Effect | Safety | Psychotropic Drugs | Anesthetics, Intravenous | Anesthetics

China
Prof Gérard WAEBER
Centre Hospitalier Universitaire Vaudois; University of Lausanne; Center for...

Terminated

A Double Blind Randomised Placebo-controlled Trial to Assess the Role of Iron Repletion in Glucose Homeostasis. (DIAFER)

Iron-deficiency | Safety Issues | Metabolic Disorder, Glucose | Iron Toxicity | Glucose Metabolism Disorders (Including Diabetes Mellitus) | Metabolic Side Effects of Drugs

Switzerland
Saint-Joseph University

Completed

Evaluation of Efficacy and Safety of Subcutaneous Acetaminophen (APAPSubQ)

Pain | Fever | Drug Effect | Drug Reaction

Lebanon
Psychiatric Centre Rigshospitalet
University of Cambridge; University Hospital, Gentofte, Copenhagen

Unknown

Does a GLP-1 Receptor Agonist Change Glucose Tolerance in Antipsychotic-treated Patients? (GREAT)

Impaired Glucose Tolerance Associated With Drugs

Denmark
Mayo Clinic

Not yet recruiting

Pharmacogenetic Panel to Prevent Adverse Drug Reactions in Daily Primary Care Practice: (PREPARE-Mayo)

Side Effect of Drug | Pharmacogenomic Drug Interaction | Drug Metabolism, Poor, CYP2D6-Related | Ineffective Drug Action | Drug Metabolism, Poor, CYP2C19-Related

United States
Oslo University Hospital

Active, not recruiting

Effects of Switching From Racemic Methadone to R-methadone on QTc Intervals (MePhaCard)

Drug Effect | Adverse Drug Effect | Heart Arrhythmia

Norway
Tetraphase Pharmaceuticals, Inc.
Department of Health and Human Services

Completed

Safety and Pharmacokinetic (PK) Study to Assess Bronchopulmonary Disposition of IV Eravacycline (TP-434) in Healthy Men and Women (BAL)

Normal Drug Tolerance

United States
Seoul National University Hospital
Asan Medical Center; Myongji Hospital

Unknown

The Effect of Ondansetron During Intramuscular Ketamine Use in Children: A Trial in Emergency Department

Side Effect of Drug | Sedation and Analgesia

Korea, Republic of
Izmir Ataturk Training and Research Hospital

Not yet recruiting

The Effects Of Anticholinergic Burden On Daily Living Activities In Elderly Patients

Psychotropic Agents Causing Adverse Effects in Therapeutic Use | Anticholinergic Adverse Reaction | Anticholinergic Syndrome | Antiarrhythmic Drug Adverse Reaction | Antiparkinsonism Drugs Causing Adverse Effects in Therapeutic Use | Antispasmodic Adverse Reaction
St. Antonius Hospital
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

Completed

Pharmacokinetics of Morphine and Oxycodone in Frail Elderly Undergoing Cardiac Surgery

Postoperative Pain | Opioid Use | Side Effect of Drug

Netherlands
Guangdong Provincial Hospital of Traditional Chinese...
Peking Union Medical College Hospital

Not yet recruiting

Efficacy and Safety of Expanded UCMSCs On Patients With Moderate to Severe Psoriasis (UCMSCs)

Psoriasis | Drug Effect | Drug Toxicity | Mesenchymal Stromal Cells

China
Guangdong Provincial Hospital of Traditional Chinese...

Completed

Efficacy and Safety of AD-MSCs Plus Calpocitriol Ointment in Patients With Moderate to Severe Psoriasis

Psoriasis | Drug Effect | Drug Toxicity | Mesenchymal Stromal Cells

China
Guangdong Provincial Hospital of Traditional Chinese...

Completed

Safety and Efficacy of Expanded Allogeneic AD-MSCs in Patients With Moderate to Severe Psoriasis (ADMSP)

Psoriasis | Drug Effect | Drug Toxicity | Mesenchymal Stromal Cells

China
Guangdong Provincial Hospital of Traditional Chinese...

Completed

Efficacy and Safety of AD-MSCs Plus Calpocitriol Ointment and PSORI-CM01 Granule in Psoriasis Patients

Psoriasis | Drug Effect | Drug Toxicity | Mesenchymal Stromal Cells

China
NHS Greater Glasgow and Clyde
Public Health Scotland

Recruiting

ASSIST: A Surveillance Study of Illicit Substance Toxicity (ASSIST)

Drug Effect | Drug Use | Drug Abuse | Drug Toxicity | Illicit Drug Use | Overdose, Drug | Illicit Drug Overdose | Illicit Drug Intoxication

United Kingdom
Washington University School of Medicine

Completed

Efavirenz and Ritonavir on Human Brain P-Glycoprotein

Drug Effects

United States
Clinical Hospital Centre Zagreb
Croatian Science Foundation; University of Zagreb School of Medicine

Recruiting

Pharmacogenomics in Prediction of Cardiovascular Drugs Adverse Reaction

Drug-Related Side Effects and Adverse Reactions | Pharmacogenetics | Cardiovascular Drugs

Croatia
Istanbul University - Cerrahpasa (IUC)

Completed

Perioperative Hypersensitivity in Children

Drug Allergy

Turkey
University Hospital, Gentofte, Copenhagen
Research Unit Of General Practice, Copenhagen

Completed

Drug Allergy Labels After Drug Allergy Investigation

Drug Hypersensitivity

Denmark
Suodi ZHAI
Peking University; The Second Hospital of Hebei Medical University; West China... and other collaborators

Completed

Post-Marketing Surveillance of the Tanreqing Injection: a Real World Study

Adverse Drug Reaction | Drug Allergy

China
University Hospital, Strasbourg, France

Recruiting

GERAP's Epidemiological Survey on Perioperative Hypersensitivity Reactions (SERAP)

Hypersensitivity, Drug

France
Dana-Farber Cancer Institute
Novartis Pharmaceuticals

Completed

Study of Omalizumab as Adjuvant Therapy in Chemotherapy Desensitization

Drug Allergy

United States
Technical University of Munich

Completed

Neural Mechanisms of Sevoflurane Induced Anesthesia: an EEG fMRI Study in Healthy Volunteers

Anesthesia | Drug Effects

Germany
Glostrup University Hospital, Copenhagen

Completed

Pupillary Response After Glaucoma Medication (pupil)

Drug Effect (Glaucoma Drugs)

Denmark
Peking Union Medical College Hospital

Unknown

Prediction of Rituximab Hypersensitivity and Desensitization Treatment

Drug Hypersensitivity Reaction

China
Tanta University

Completed

The Effect of Opioid Free Anesthesia in Bariatric Surgeries (Opioidfree)

Adverse Effect of Drugs and Medicaments in Therapeutic Use | Adverse Effects in the Therapeutic Use of Anaesthetics

Egypt
Seoul National University Hospital

Recruiting

High Dimensional Analysis of Immune Cells in Pediatric Patients

Neuromuscular Blockade | Drug Allergy

Korea, Republic of
Saglik Bilimleri Universitesi

Completed

The Knowledge, Attitudes and Practices of Healthcare Workers on Drug Hypersensitivity Reactions in Children (KAPHWDHRC)

Adverse Drug Reactions

Turkey
Alexandria University

Completed

Lubiprostone for Functional Constipation in the Under 18 Years Patients

Drug Side Effect | Treatment Efficacy | Clinical Efficacy

Egypt
Central South University

Unknown

The Clinical Study on Pseudo-allergic Reaction to Anesthetic Drugs During General Anesthesia

General Anesthetic Drug Allergy

China
Takeda

Completed

A Study to Assess the Hypersensitivity to TAK-880 Compared to Gammagard S/D in Blood of Children, Teenagers and Adults

Drug Hypersensitivity

United States
University Hospital, Montpellier
European Commission

Completed

Medical Device for Drug Allergy Diagnosis (COBIOPHAD)

Drug Hypersensitivity

France
University Hospital, Montpellier

Completed

Predictive Models for Betalactam Allergy

Drug Hypersensitivity

Clinical Trials on Immune Tolerance/Drug Effects

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Jamaica

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations