Clinical Trials on Immune Checkpoint Inhibitors in Germany

Total 3851 results

GWT-TUD GmbH

Completed

Facilitated Immunoglobulin Administration Registry and Outcomes Study (FIGARO) (FIGARO)

Primary Immunodeficiency | Secondary Immune Deficiency

Germany, Italy, France
University Hospital Tuebingen

Recruiting

Effect of Weight Loss on Brain Insulin Sensitivity in Humans

Insulin Resistance

Germany
University Hospital Tuebingen
German Center for Diabetes Research

Unknown

Improving Insulin Sensitivity by Non-invasive Brain Stimulation in Persons With Insulin Resistance

Insulin Resistance | Transcranial Direct Current Stimulation

Germany
University of Erlangen-Nürnberg Medical School

Completed

Comparing the Efficacy of Periarticular Bone Structure in Patients Treated With Either Tocilizumab or Tumor Necrosis Factor Blockers (Re-Bone)

Rheumatoid Arthritis

Germany
University Hospital Tuebingen

Completed

Influence of Central Nervous Insulin Action on Insulin Sensitivity of Peripheral Organs in Lean Versus Overweight Humans

Insulin Resistance

Germany
University Hospital Tuebingen

Completed

Influence of Brain Insulin Sensitivity on Peripheral Insulin Sensitivity

Insulin Sensitivity

Germany
Technische Universität Dresden
Dr. Falk Pharma GmbH

Completed

Budesonide for Prevention of Acute Gastrointestinal GVHD Following Allogenic Stem Cell Transplantation

Leukemia | Graft-Versus-Host Disease

Germany
Goethe University
HIVCENTER

Unknown

Safety and Immune Response to Adjuvanted A(H1N1)v Influenza Vaccine in HIV-1 Infected and Immunosuppressed Adult Patients

Cancer | Immunosuppression | HIV-1 Infection

Germany
Charite University, Berlin, Germany

Unknown

Intraarticular Opioids Vs Glucocorticosteroids in Gonarthritis

Rheumatic Disease

Germany
GlaxoSmithKline

Completed

A Clinical Study to Investigate the Dermal and Ocular Tolerance of a Developmental Cosmetic Facial Serum Formulation in Healthy Females With Sensitive Skin

Skin Care

Germany
Pfizer
ViiV Healthcare

Completed

A Study in Asymptomatic HIV Infected Patients to Investigate Pharmacodynamics, Pharmacokinetics, Safety and Toleration of UK-453,061

HIV-1

Germany
University Hospital Tuebingen

Completed

"Effect of Central Insulin Administration on Whole-body Insulin Sensitivity in Women"

Insulin Sensitivity

Germany
Technische Universität Dresden
Aesculap AG

Completed

Serum Metal Ion Concentration After Total Knee Arthroplasty (TKA)

Osteoarthritis | Metal Ion Levels

Germany
Aesculap AG

Terminated

Minimally Invasive Versus Conventional Approaches in Navigated Total Knee Arthroplasty (TKA)

Osteoarthritis | Rheumatoid Arthritis | Post-traumatic Arthritis

Germany
Rockefeller University
University of Cologne

Completed

A Study of the Safety, Pharmacokinetics and Antiretroviral Activity of 10-1074

Healthy | HIV

Germany, United States
University Hospital, Saarland

Completed

Prognostic Relevance of High-sensitivity Troponin in Patients With Acute Decompensated Heart Failure

Heart Failure

Germany
Sanofi

Completed

Multiple Ascending Dose Study To Assess The Safety Profile Of SAR113244 Versus Placebo In Lupus Male And Female Patients

Systemic Lupus Erythematosus

Germany
JADO Technologies GmbH

Completed

Efficacy and Safety of TF002 in Cutaneous Mastocytosis

Cutaneous Mastocytosis

Germany
Zalicus

Completed

A Phase I Study to Assess the Safety and Tolerability of Topical CRx-197 Formulations in Healthy Volunteers

Atopic Dermatitis

Germany
Bausch & Lomb Incorporated

Completed

Study to Explore the Pharmacokinetics and Pharmacodynamics of Epinephrine in Healthy Male and Female Subjects With Different Skin to Muscle Depth (STMD)

Anaphylaxis

Germany
University of Hohenheim
Universität Tübingen

Completed

Oral Bioavailability and Bioactivity of Prenylflavonoids From Hops

Safety After Oral Intake | Pharmacokinetics After Oral Intake | Immune Cells Activity

Germany
Bionor Immuno AS
Celgene Corporation

Completed

Vacc-4x + Lenalidomide vs. Vacc-4x +Placebo in HIV-1-infected Subjects on Antiretroviral Therapy (ART) (IMID)

HIV-1 Infection

Germany
Waldfriede Hospital

Completed

Study of Wrist Fusions With the Medartis Aptus Arthrodesis Plate (STIF)

Wrist Arthritis | Wrist Osteoarthritis

Germany
Allergopharma GmbH & Co. KG

Completed

Evaluation of Safety and Efficacy of Specific Immunotherapy With Recombinant Major Allergens of Timothy Grass Pollen Adsorbed Onto Aluminium-hydroxide in Patients With IgE-mediated Allergic Rhinoconjunctivitis +/- Controlled Asthma (AMETHYST)

Rhinoconjunctivitis

Germany
Allergopharma GmbH & Co. KG

Completed

Open Label Safety Study of a Birch Pollen Allergen Extract

Rhinoconjunctivitis

Germany
Moberg Pharma AB

Completed

Assessment of the Effects on Barrier Impairment, Clinical Features and Bacterial Colonization of Topical Formulations in Patients With Atopic Eczema; a Phase IIa, Single-center, Randomized, Observer-blind Study

Atopic Dermatitis

Germany
GlaxoSmithKline

Completed

GSK2190915 Safety and Pharmacokinetic Study in Healthy Japanese Subjects

Asthma

Germany
Novartis Pharmaceuticals

Terminated

Multiple Ascending Dose Study of MHS552 in Adults Participants With Systemic Lupus Erythematosus (SLE)

Lupus Erythematosus, Systemic

Germany
Philipps University Marburg Medical Center

Completed

Long-term Effects ReSet Your Mind - Mechanisms

Depression Moderate | Depression Mild

Germany
Creabilis SA

Withdrawn

CT 327 in the "Atopy Patch Test" Model (CT327 AD01-09)

Atopic Dermatitis

Germany
Allergopharma GmbH & Co. KG

Completed

Dose Range Finding Study With rBet v1-FV - in Adult Patients With Birch Pollen-Allergic Seasonal Rhinoconjunctivitis

Allergic Rhinoconjunctivitis

Germany
Technical University of Munich
Max-Planck Institute for Biological Cybernetics

Recruiting

Eye Movement Behaviour and Pupil Size in Natural Outdoor and Indoor Scenes

Light Sensitivity

Germany
Charite University, Berlin, Germany

Terminated

Chronic Urticaria - Long Term Assessment of Effects of Rupatadine

Chronic Urticaria

Germany
RWTH Aachen University

Completed

Prehospital Emergency Care of Obstructive Respiratory Emergencies With the Use of Teleconsultation

Asthma | COPD

Germany
Allergopharma GmbH & Co. KG

Completed

Multicenter Trial of Immunotherapy With House Dust Mite Allergoid (ACRI)

Rhinoconjunctivitis

Germany
Charite University, Berlin, Germany

Completed

Immunomodulation of E.Coli Nissle 1917 in Patients With Grass Pollen Rhinoconjunctivitis (Ecorhino)

Rhinoconjunctivitis

Germany
Technical University of Munich
Gilead Sciences; MUC Research GmbH

Completed

Changes in Insulin Resistance in Healthy Volunteers on STRIBILD® Medication

Insulin Resistance

Germany
Novo Nordisk A/S

Recruiting

A Research Study Looking at Long-term Treatment With Mim8 in People With Haemophilia A (FRONTIER 4) (FRONTIER4)

Haemophilia A With Inhibitors | Haemophilia A

Taiwan, Canada, Spain, Netherlands, Korea, Republic of, India, United States, United Kingdom, China, Portugal, Lithuania, Turkey, South Africa, Ireland, Italy, France, Japan, Belgium, Malaysia, Poland, Austria, Bulgaria, Denmark, Germany and more
Neodyne Biosciences, Inc.

Recruiting

De-tensioning Patch, in Subjects With Type 1 Diabetes and Lipohypertrophy

Insulin Resistance | Lipohypertrophy

Germany
Klinik für Kardiologie, Pneumologie und Angiologie

Completed

Clinical Impact of Autonomic Modulation After Pulmonary Vein Isolation

Atrial Fibrillation

Germany
Marcus Maurer
Charite University, Berlin, Germany

Terminated

Efficacy and Safety of Miltefosine in Antihistamine Resistant Chronic Urticaria (MIARCU)

Chronic Urticaria

Germany
Kinderkrankenhaus auf der Bult
Medtronic International Trading Sarl

Completed

"MiniMed 640G System" User Evaluation With the Question of Reducing the Rate of Hypoglycemia

Type 1 Diabetes

Germany
Charite University, Berlin, Germany
Essex Pharma GmbH

Completed

Effects of 5 mg vs. 20 mg Desloratadine on Skin Lesions in Patients With Chronic Urticaria (CU) (AUD2OCU)

Chronic Urticaria

Germany
Heidelberg University

Completed

Age Gender Left Ventricular Mass and Cardiac Troponin T

Heart Failure

Germany
Evangelisches Klinikum Köln Weyertal gGmbH
University of Cologne

Recruiting

Neuropathological Changes of the Intestinal Wall in Patients With Bowel Evacuation Disorders (Constipation)

Autoimmune Diseases | Neuropathology | Defecation Disorder

Germany
Novo Nordisk A/S

Recruiting

A Research Study Investigating Mim8 in Adults and Adolescents With Haemophilia A With or Without Inhibitors

Haemophilia A With Inhibitors | Haemophilia A

United States, Korea, Republic of, France, Spain, Romania, Canada, Taiwan, China, Lithuania, Netherlands, India, South Africa, Russian Federation, Austria, Belgium, Czechia, Denmark, Ireland, Italy, Japan, Latvia, Malaysia, Mexico, Po... and more
Technical University of Munich

Unknown

EUS-guided Procore-biopsy in Diagnosing Autoimmune Pancreatitis

Autoimmune Pancreatitis

Germany
Philipps University Marburg Medical Center

Completed

An Online Intervention Targeting Depression and Low Reward Sensitivity

Depression Moderate | Depression Mild

Germany
Bayer

Completed

BAY1830839: First in Man, Single Dose Escalation, Safety & Tolerability and Pharmacokinetics

Arthritis, Rheumatoid

Germany
Aesculap AG

Completed

Comparison of Rotating vs. Fixed Platform of the COLUMBUS Knee Prosthesis

Osteoarthritis | Rheumatoid Arthritis | Post-traumatic; Arthrosis

Germany

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