Eye Movement Behaviour and Pupil Size in Natural Outdoor and Indoor Scenes

Characterization of Eye Movement Behaviour and Pupil Size Through Eye-tracking in Natural Outdoor and Indoor Scenes

In this study, the researchers will be using eye tracking and detailed lighting measurements to understand how different types of indoor and outdoor lighting affect the eye movements and pupil sizes of our participants. Participants will be paired up and undergo six eye tracking sessions, split across two appointments. Each appointment will involve viewing either indoor or outdoor scenes, and before each session, participants will spend time adapting to the lighting conditions. Overall, each participant will spend 24 minutes being tracked, and the entire study will take about 2-3 hours to complete. The investigators expect differences in eye movements and pupil size between indoor and outdoor scenes.

Study Overview

• Status: Recruiting
• Conditions: Light Sensitivity
• Intervention / Treatment: Other: Indoor vs. outdoor scenes

• Study Type: Interventional
• Enrollment (Estimated): 24
• Phase: Not Applicable

Contacts and Locations

• Study Contact: Name: Alexander Hahn; Phone Number: +49(0)70716011670; Email: alexander.hahn@tuebingen.mpg.de
• Study Contact Backup: Name: Manuel Spitschan, PhD; Email: manuel.spitschan@tuebingen.mpg.de

Study Locations

• Germany
  • Tübingen, Germany, 72076
    • Recruiting
    • Max Planck Institute for Biological Cybernetics
    • Contact: Alexander Hahn

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult
• Accepts Healthy Volunteers: Yes

Description

Inclusion Criteria:

• No previous eye-surgeries or ocular impairments like anisometropia, amblyopia, strabism, cataract, watery eyes or hanging eye lids
• Normal or corrected-to-normal visual acuity (+3dpt. to -5dpt.)
• Normal colour vision
• Normal binocular vision

Exclusion Criteria:

• Any use of medications or drugs that influence photosensitivity or the ability to concentrate
• Excessive alcohol and/or drug use
• Presence of psychiatric disorders
• Poor sleep quality
• Diagnosed with epilepsy

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Basic Science
• Allocation: N/A
• Interventional Model: Single Group Assignment
• Masking: None (Open Label)

Number of Arms

1

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: Eye-tracking, pupillometry and scene rating indoors & outdoors	Other: Indoor vs. outdoor scenes; Light conditions in indoor (artificial light) and outdoor (daylight) settings

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Saccade frequency - Indoor scene 1	Number per second [n/s]	Baseline
Saccade frequency - Indoor scene 2	Number per second [n/s]	Baseline
Saccade frequency - Indoor scene 3	Number per second [n/s]	Baseline
Saccade frequency - Outdoor scene 1	Number per second [n/s]	Baseline
Saccade frequency - Outdoor scene 2	Number per second [n/s]	Baseline
Saccade frequency - Outdoor scene 3	Number per second [n/s]	Baseline
Saccade amplitude - Indoor scene 1	Mean angular distance traveled [°]	Baseline
Saccade amplitude - Indoor scene 2	Mean angular distance traveled [°]	Baseline
Saccade amplitude - Indoor scene 3	Mean angular distance traveled [°]	Baseline
Saccade amplitude - Outdoor scene 1	Mean angular distance traveled [°]	Baseline
Saccade amplitude - Outdoor scene 2	Mean angular distance traveled [°]	Baseline
Saccade amplitude - Outdoor scene 3	Mean angular distance traveled [°]	Baseline
Saccade velocity - Indoor scene 1	Mean peak velocity [°/s]	Baseline
Saccade velocity - Indoor scene 2	Mean peak velocity [°/s]	Baseline
Saccade velocity - Indoor scene 3	Mean peak velocity [°/s]	Baseline
Saccade velocity - Outdoor scene 1	Mean peak velocity [°/s]	Baseline
Saccade velocity - Outdoor scene 2	Mean peak velocity [°/s]	Baseline
Saccade velocity - Outdoor scene 3	Mean peak velocity [°/s]	Baseline
Fixation duration - Indoor scene 1	Mean fixation duration [s]	Baseline
Fixation duration - Indoor scene 2	Mean fixation duration [s]	Baseline
Fixation duration - Indoor scene 3	Mean fixation duration [s]	Baseline
Fixation duration - Outdoor scene 1	Mean fixation duration [s]	Baseline
Fixation duration - Outdoor scene 2	Mean fixation duration [s]	Baseline
Fixation duration - Outdoor scene 3	Mean fixation duration [s]	Baseline
Fixation frequency - Indoor scene 1	Number per minute [n/min]	Baseline
Fixation frequency - Indoor scene 2	Number per minute [n/min]	Baseline
Fixation frequency - Indoor scene 3	Number per minute [n/min]	Baseline
Fixation frequency - Outdoor scene 1	Number per minute [n/min]	Baseline
Fixation frequency - Outdoor scene 2	Number per minute [n/min]	Baseline
Fixation frequency - Outdoor scene 3	Number per minute [n/min]	Baseline
Pupil size - Indoor scene 1	Mean pupil size [mm]	Baseline
Pupil size - Indoor scene 2	Mean pupil size [mm]	Baseline
Pupil size - Indoor scene 3	Mean pupil size [mm]	Baseline
Pupil size - Outdoor scene 1	Mean pupil size [mm]	Baseline
Pupil size - Outdoor scene 2	Mean pupil size [mm]	Baseline
Pupil size - Outdoor scene 3	Mean pupil size [mm]	Baseline
Melanopic irradiance - Indoor scene 1	Irradiance [W/(sqm*nm)]	Baseline
Melanopic irradiance - Indoor scene 2	Irradiance [W/(sqm*nm)]	Baseline
Melanopic irradiance - Indoor scene 3	Irradiance [W/(sqm*nm)]	Baseline
Melanopic irradiance - Outdoor scene 1	Irradiance [W/(sqm*nm)]	Baseline
Melanopic irradiance - Outdoor scene 2	Irradiance [W/(sqm*nm)]	Baseline
Melanopic irradiance - Outdoor scene 3	Irradiance [W/(sqm*nm)]	Baseline
Photopic illuminance - Indoor scene 1	Illuminance [lux]	Baseline
Photopic illuminance - Indoor scene 2	Illuminance [lux]	Baseline
Photopic illuminance - Indoor scene 3	Illuminance [lux]	Baseline
Photopic illuminance - Outdoor scene 1	Illuminance [lux]	Baseline
Photopic illuminance - Outdoor scene 2	Illuminance [lux]	Baseline
Photopic illuminance - Outdoor scene 3	Illuminance [lux]	Baseline

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Subjective scene ratings - Indoor scene 1	Unabbreviated scale titles (1)., min. and max, values (2.), score assessment (3.):; 1. "How beautiful is this scene to you?" 2. "1 = not beautiful at all; 10 = extremely beautiful" 3. No better or worse outcome; 1. "How would you rate the brightness of this scene?" 2. "1 = dimly lit room; 10 = bright sunny day" 3. No better or worse outcome; 1. "How visually comfortable did you find this scene?" 2. "1 = No discomfort; 10 = Very uncomfortable" 3. No better or worse outcome; 1. "How would you rate the complexity of the scene (e.g. colour contrasts, different object identities, moving objects)?" 2. "1 = very simple; 10 = Very complex" 3. No better or worse outcome; 1. "How sleepy do you currently feel" 2. "1 = Extremely alert; 10 = Extremely sleep, can't keep awake" 3. Lower score is better	Baseline
Subjective scene ratings - Indoor scene 2	Unabbreviated scale titles (1)., min. and max, values (2.), score assessment (3.):; 1. "How beautiful is this scene to you?" 2. "1 = not beautiful at all; 10 = extremely beautiful" 3. No better or worse outcome; 1. "How would you rate the brightness of this scene?" 2. "1 = dimly lit room; 10 = bright sunny day" 3. No better or worse outcome; 1. "How visually comfortable did you find this scene?" 2. "1 = No discomfort; 10 = Very uncomfortable" 3. No better or worse outcome; 1. "How would you rate the complexity of the scene (e.g. colour contrasts, different object identities, moving objects)?" 2. "1 = very simple; 10 = Very complex" 3. No better or worse outcome; 1. "How sleepy do you currently feel" 2. "1 = Extremely alert; 10 = Extremely sleep, can't keep awake" 3. Lower score is better	Baseline
Subjective scene ratings - Indoor scene 3	Unabbreviated scale titles (1)., min. and max, values (2.), score assessment (3.):; 1. "How beautiful is this scene to you?" 2. "1 = not beautiful at all; 10 = extremely beautiful" 3. No better or worse outcome; 1. "How would you rate the brightness of this scene?" 2. "1 = dimly lit room; 10 = bright sunny day" 3. No better or worse outcome; 1. "How visually comfortable did you find this scene?" 2. "1 = No discomfort; 10 = Very uncomfortable" 3. No better or worse outcome; 1. "How would you rate the complexity of the scene (e.g. colour contrasts, different object identities, moving objects)?" 2. "1 = very simple; 10 = Very complex" 3. No better or worse outcome; 1. "How sleepy do you currently feel" 2. "1 = Extremely alert; 10 = Extremely sleep, can't keep awake" 3. Lower score is better	Baseline
Subjective scene ratings - Outdoor scene 1	Unabbreviated scale titles (1)., min. and max, values (2.), score assessment (3.):; 1. "How beautiful is this scene to you?" 2. "1 = not beautiful at all; 10 = extremely beautiful" 3. No better or worse outcome; 1. "How would you rate the brightness of this scene?" 2. "1 = dimly lit room; 10 = bright sunny day" 3. No better or worse outcome; 1. "How visually comfortable did you find this scene?" 2. "1 = No discomfort; 10 = Very uncomfortable" 3. No better or worse outcome; 1. "How would you rate the complexity of the scene (e.g. colour contrasts, different object identities, moving objects)?" 2. "1 = very simple; 10 = Very complex" 3. No better or worse outcome; 1. "How sleepy do you currently feel" 2. "1 = Extremely alert; 10 = Extremely sleep, can't keep awake" 3. Lower score is better	Baseline
Subjective scene ratings - Outdoor scene 2	Unabbreviated scale titles (1)., min. and max, values (2.), score assessment (3.):; 1. "How beautiful is this scene to you?" 2. "1 = not beautiful at all; 10 = extremely beautiful" 3. No better or worse outcome; 1. "How would you rate the brightness of this scene?" 2. "1 = dimly lit room; 10 = bright sunny day" 3. No better or worse outcome; 1. "How visually comfortable did you find this scene?" 2. "1 = No discomfort; 10 = Very uncomfortable" 3. No better or worse outcome; 1. "How would you rate the complexity of the scene (e.g. colour contrasts, different object identities, moving objects)?" 2. "1 = very simple; 10 = Very complex" 3. No better or worse outcome; 1. "How sleepy do you currently feel" 2. "1 = Extremely alert; 10 = Extremely sleep, can't keep awake" 3. Lower score is better	Baseline
Subjective scene ratings - Outdoor scene 3	Unabbreviated scale titles (1)., min. and max, values (2.), score assessment (3.):; 1. "How beautiful is this scene to you?" 2. "1 = not beautiful at all; 10 = extremely beautiful" 3. No better or worse outcome; 1. "How would you rate the brightness of this scene?" 2. "1 = dimly lit room; 10 = bright sunny day" 3. No better or worse outcome; 1. "How visually comfortable did you find this scene?" 2. "1 = No discomfort; 10 = Very uncomfortable" 3. No better or worse outcome; 1. "How would you rate the complexity of the scene (e.g. colour contrasts, different object identities, moving objects)?" 2. "1 = very simple; 10 = Very complex" 3. No better or worse outcome; 1. "How sleepy do you currently feel" 2. "1 = Extremely alert; 10 = Extremely sleep, can't keep awake" 3. Lower score is better	Baseline
Geographical scene location - Indoor scene 1	Longitude and latitude [°]	Baseline
Geographical scene location - Indoor scene 2	Longitude and latitude [°]	Baseline
Geographical scene location - Indoor scene 3	Longitude and latitude [°]	Baseline
Geographical scene location - Outdoor scene 1	Longitude and latitude [°]	Baseline
Geographical scene location - Outdoor scene 2	Longitude and latitude [°]	Baseline
Geographical scene location - Outdoor scene 3	Longitude and latitude [°]	Baseline
Ambient temperature - Indoor scene 1	Temperature [°C]	Baseline
Ambient temperature - Indoor scene 2	Temperature [°C]	Baseline
Ambient temperature - Indoor scene 3	Temperature [°C]	Baseline
Ambient temperature - Outdoor scene 1	Temperature [°C]	Baseline
Ambient temperature - Outdoor scene 2	Temperature [°C]	Baseline
Ambient temperature - Outdoor scene 3	Temperature [°C]	Baseline

Collaborators and Investigators

• Sponsor: Technical University of Munich
• Collaborators: Max-Planck Institute for Biological Cybernetics
• Investigators: Principal Investigator: Manuel Spitschan, PhD, Technical University of Munich & Max Planck Institute for Biological Cybernetics

Study record dates

Study Major Dates

• Study Start (Actual): July 1, 2023
• Primary Completion (Estimated): August 31, 2023
• Study Completion (Estimated): July 31, 2024

Study Registration Dates

• First Submitted: June 5, 2023
• First Submitted That Met QC Criteria: July 24, 2023
• First Posted (Actual): August 2, 2023

Study Record Updates

• Last Update Posted (Actual): August 2, 2023
• Last Update Submitted That Met QC Criteria: July 24, 2023
• Last Verified: July 1, 2023

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Nervous System Diseases; Eye Diseases; Neurologic Manifestations; Sensation Disorders; Vision Disorders; Photophobia
• Other Study ID Numbers: MPI-TSCN-2023-NATURALEYE; 2023-231-S-KH (Other Identifier: Ethikkommission der Technischen Universität München)

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: YES

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No