Clinical Trials on Immunization; Infection

Total 61045 results

SOTIO Biotech AG
SOTIO Biotech a.s.

Active, not recruiting

Study of SO-C101 and SO-C101 in Combination With Pembro in Adult Patients With Advanced/Metastatic Solid Tumors

Melanoma | Renal Cell Carcinoma | Cervical Cancer | Hepatocellular Carcinoma | Gastric Cancer | Ovarian Cancer | Non Small Cell Lung Cancer | Mesothelioma | Bladder Cancer | Triple Negative Breast Cancer | Small-cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Thyroid | Anal Cancer | Merkel Cell Carcinoma | Biliary... and other conditions

United States, France, Spain, Czechia
Morphotek
National Cancer Institute (NCI); Children's Oncology Group

Completed

MORAb-004 in Treating Young Patients With Recurrent or Refractory Solid Tumors or Lymphoma

Unspecified Childhood Solid Tumor, Protocol Specific | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma and other conditions

United States
Duke University
Wallace H. Coulter Foundation

Completed

Point of Care 3D Ultrasound for Various Applications: A Pilot Study

Digestive System Diseases | Gastrointestinal Diseases | Ovarian Cysts | Intestinal Diseases | Intraabdominal Infections | Pregnancy | Polyps | Appendicitis | Diverticulitis | Pancreatitis | Gallstones | Aortic Aneurysm | Abdominal Injuries | Pregnancy, Ectopic | Uterine Fibroids | Kidney Stones | Tumors | Vascular Disease | Evidence... and other conditions

United States
Northwestern University
Amgen

Terminated

Dose-Escalation Trial of Carfilzomib With and Without Romidepsin in Cutaneous T-Cell Lymphoma

Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma | Recurrent Mycosis Fungoides/Sezary Syndrome | Stage III Cutaneous T-cell Non-Hodgkin Lymphoma | Stage IV Cutaneous T-cell Non-Hodgkin Lymphoma | Stage I Cutaneous T-cell Non-Hodgkin Lymphoma | Stage IA Mycosis Fungoides/Sezary Syndrome | Stage... and other conditions

United States
Medicenna Therapeutics, Inc.
Merck Sharp & Dohme LLC

Recruiting

A Beta-only IL-2 ImmunoTherapY Study (ABILITY-1)

Clear Cell Renal Cell Carcinoma | Cervical Cancer | Gastric Cancer | Esophageal Cancer | Ovarian Cancer | Fallopian Tube Cancer | Solid Tumor | Squamous Cell Carcinoma of Head and Neck | Bladder Cancer | Skin Cancer | Triple Negative Breast Cancer | Advanced Solid Tumor | Primary Peritoneal Cancer | Endometrial Carcinoma and other conditions

United States, Australia, Korea, Republic of, Canada
Vanderbilt-Ingram Cancer Center
National Cancer Institute (NCI)

Withdrawn

Veliparib, Capecitabine, and Temozolomide in Patients With Advanced, Metastatic, and Recurrent Neuroendocrine Tumor

Merkel Cell Carcinoma | Neuroendocrine Neoplasm | Metastatic Carcinoid Tumor | Functional Pancreatic Neuroendocrine Tumor | Malignant Somatostatinoma | Metastatic Adrenal Gland Pheochromocytoma | Multiple Endocrine Neoplasia Type 1 | Multiple Endocrine Neoplasia Type 2A | Multiple Endocrine Neoplasia... and other conditions
Mayo Clinic
National Cancer Institute (NCI)

Suspended

Direct Tumor Microinjection and FDG-PET in Testing Drug Sensitivity in Patients With Relapsed or Refractory Non-Hodgkin Lymphoma, Hodgkin Lymphoma, or Stage IV Breast Cancer

Recurrent Hodgkin Lymphoma | Refractory Hodgkin Lymphoma | Recurrent Non-Hodgkin Lymphoma | Refractory Non-Hodgkin Lymphoma | Recurrent Breast Carcinoma | Recurrent Mycosis Fungoides | Recurrent Primary Cutaneous T-Cell Non-Hodgkin Lymphoma | Stage IV Breast Cancer AJCC v6 and v7 | Breast Adenocarcinoma and other conditions

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Romidepsin, Ifosfamide, Carboplatin, and Etoposide in Treating Participants With Relapsed or Refractory Peripheral T-Cell Lymphoma

Mycosis Fungoides | Recurrent Angioimmunoblastic T-Cell Lymphoma | Refractory Angioimmunoblastic T-Cell Lymphoma | Refractory Anaplastic Large Cell Lymphoma | Recurrent Anaplastic Large Cell Lymphoma | Refractory Peripheral T-Cell Lymphoma, Not Otherwise Specified | Recurrent Enteropathy-Associated... and other conditions

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Withdrawn

Genetically Modified Peripheral Blood Stem Cell Transplant in Treating Patients With HIV-Associated Non-Hodgkin or Hodgkin Lymphoma

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma and other conditions

United States
National Cancer Institute (NCI)

Completed

17-DMAG in Treating Patients With Metastatic or Unresectable Solid Tumors or Lymphomas

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma and other conditions

United States
National Cancer Institute (NCI)

Completed

MS-275 and Isotretinoin in Treating Patients With Metastatic or Advanced Solid Tumors or Lymphomas

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma and other conditions

United States
Massachusetts General Hospital
Patient-Centered Outcomes Research Institute

Not yet recruiting

A Decentralized Clinical Trial to Promote Evidence-Based Care for Underserved Patients With Neurofibromatosis 1

Neurofibromatosis 1

United States
Shanghai General Hospital, Shanghai Jiao Tong University...

Not yet recruiting

Intensive Conditioning With Thiotepa Combined With Bu/Flu/Ara-C in Allo-HSCT for Myeloid Malignancies With Extramedullary Involvement

Acute Myeloid Leukemia | Chronic Myelomonocytic Leukemia | Myeloid Sarcoma | Myelodysplastic Neoplasm | Extramedullary Myeloid Tumor
Danone Specialized Nutrition

Recruiting

Impact of a New Plant-based High-energy Oral Nutritional Supplement on Nutritional Outcomes in Malnourished Patients

Cancer | Inflammatory Bowel Diseases | Malnutrition | Hiv | Chronic Obstructive Pulmonary Disease (COPD)

Spain
Shanghai Yunying Medical Technology
Eye & ENT Hospital of Fudan University

Recruiting

A Clinical Study on Oncolytic Virus Injection (R130 OV) for the Treatment of Relapsed/Refractory Head and Neck Cancer

Head and Neck Cancer | Laryngeal Cancer | Otorhinolaryngologic Neoplasms | Esophageal Cancer | Ear Cancer | Nose Cancer | Pharyngeal Cancer

China
Duke University
National Institute of Allergy and Infectious Diseases (NIAID); University of... and other collaborators

Recruiting

COVID-19 Vaccine Responses in PIDD Subjects

Common Variable Immunodeficiency | X-linked Agammaglobulinemia | Primary Immune Deficiency | Primary Antibody Deficiencies | CVID | XLA | Secondary Hypogammaglobulinemia

United States
Chinese University of Hong Kong

Recruiting

Impact of COVID-19 Vaccines on Cerebrovascular Health

Stroke | Brain Diseases | Brain Ischemia | Dementia | Alzheimer Disease | Venous Thromboembolism | Stroke, Ischemic | Stroke, Acute | Major Adverse Cardiovascular Event | Arterial Thromboembolism

Hong Kong
BioNTech SE

Recruiting

A Clinical Trial Investigating the Safety, Tolerability, and Therapeutic Effects of BNT113 in Combination With Pembrolizumab Versus Pembrolizumab Alone for Patients With a Form of Head and Neck Cancer Positive for Human Papilloma Virus 16 and Expressing the Protein PD-L1 (AHEAD-MERIT)

Recurrent Head and Neck Cancer | Unresectable Head and Neck Squamous Cell Carcinoma | Metastatic Head and Neck Cancer

Germany, United States, France, United Kingdom, Korea, Republic of, Spain, Poland, Belgium, Brazil, Taiwan, Italy, Canada, Czechia, Australia, Turkey, Mexico, Chile, Argentina, Austria, Hungary, Portugal, Sweden
The Methodist Hospital Research Institute
Merck Sharp & Dohme LLC

Completed

SBRT and Oncolytic Virus Therapy Before Pembrolizumab for Metastatic TNBC and NSCLC (STOMP)

Metastatic Non-small Cell Lung Cancer | Metastatic Triple-negative Breast Cancer

United States
Izmir Bakircay University

Completed

Chemotherapy-induced Peripheral Neuropathy (CIPN) on Motor and Sensory Function

Cancer | Breast Cancer | Breast Neoplasms | Colo-rectal Cancer | Chemotherapeutic Toxicity | Chemotherapy-induced Peripheral Neuropathy | Colon Neoplasm

Turkey
The University of Texas Health Science Center,...
University of California, San Francisco

Active, not recruiting

Pain Biomarker Study (PBS)

Migraine | Cluster Headache | Trigeminal Autonomic Cephalgia | Hemicrania Continua | Paroxysmal Hemicrania | SUNCT | Short-Lasting Unilateral Neuralgiform Headache With Conjunctival Injection and Tearing

United States
Centre Hospitalier Universitaire Dijon

Terminated

Mitochondrial Dysfunction of Alveolar and Circulating Immune Cells During Acute Respiratory Distress Syndrome: Impact of Infectious Aggression and Alveolar Stretching as a Result of Mechanical Ventilation. (PNEUMOCHONDRIE)

Lung Diseases | Mechanical Ventilation | Bronchoalveolar Lavage

France
University of Southampton
National University Hospital, Singapore; Singapore Institute for Clinical Sciences and other collaborators

Enrolling by invitation

NiPPeR Randomised Trial - Child Follow Up Study (NiPPeR Child)

Neurobehavioral Manifestations | Allergy | Microbial Colonization | Growth Disorders | Atopic Dermatitis | Obesity, Childhood | Metabolic Disturbance | Cognition | Lifestyle | Breastfeeding | Nutrition, Healthy | Atopy

Singapore, United Kingdom, New Zealand
University Health Network, Toronto
Sunnybrook Health Sciences Centre; The Ottawa Hospital; Mount Sinai Hospital,...

Active, not recruiting

ODYSSEE-vCHAT Mental Health Program for Heart Failure and Kidney Disease Patients (ODYSSEEvCHAT)

Chronic Kidney Diseases | Chronic Heart Failure

Canada
Duke University
Duke Institute for Health Innovation

Terminated

Hypertension Management in Cancer Patients

Hypertension | Cancer | Blood Pressure | Cancer, Breast | CLL | Cancer of Prostate | Hematopoietic Malignancy

United States
Rocket Pharmaceuticals Inc.

Active, not recruiting

Gene Therapy for Male Patients With Danon Disease (DD) Using RP-A501; AAV9.LAMP2B

Danon Disease

United States
University of Aarhus
Center for Clinical Research and Prevention

Completed

Psychological Risk Factors for Functional Somatic Disorders

Irritable Bowel Syndrome | Fibromyalgia | Somatoform Disorders | Medically Unexplained Symptoms | Chronic Fatigue Syndrome | Bodily Distress Syndrome | Medically Unexplained Syndrome
Mayo Clinic
National Cancer Institute (NCI)

Completed

Intrapleural Measles Virus Therapy in Patients With Malignant Pleural Mesothelioma

Recurrent Malignant Mesothelioma | Stage IA Malignant Mesothelioma | Stage IB Malignant Mesothelioma | Stage II Malignant Mesothelioma | Stage III Malignant Mesothelioma | Stage IV Malignant Mesothelioma

United States
Nanjing Medical University

Completed

Effect of Heart Valve Replacement on Cheyne-Stokes Respiration (CSR)

Cheyne-Stokes Respiration | Heart Valve Disease | Central Sleep Apnea

China
Vanderbilt University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Ibuprofen in Sepsis Study

Lung Diseases | Shock, Septic | Acute Respiratory Distress Syndrome
S-Evans Biosciences Co., Ltd.
First Affiliated Hospital of Zhejiang University

Unknown

Using Human Menstrual Blood Cells to Treat Acute Lung Injury Caused by H7N9 Bird Flu Virus Infection

Acute Lung Injury | Multiple Organ Failure | Acute Respiratory Distress Syndrome (ARDS)

China
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Umbilical Cord Blood Transplantation in Treating Patients With High-Risk Hematologic Cancer

Lymphoma | Myelodysplastic Syndromes | Leukemia | Myelodysplastic/Myeloproliferative Diseases | Graft Versus Host Disease

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Study of Pembrolizumab (MK-3475) in Combination With Romidepsin

Recurrent Angioimmunoblastic T-Cell Lymphoma | Recurrent Mycosis Fungoides | Recurrent Primary Cutaneous T-Cell Non-Hodgkin Lymphoma | Refractory Angioimmunoblastic T-Cell Lymphoma | Refractory Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma | Refractory Mycosis Fungoides | Refractory Anaplastic... and other conditions

United States
Mayo Clinic
National Cancer Institute (NCI)

Active, not recruiting

Pembrolizumab in Treating Patients With Stage IB-IV Mycosis Fungoides

Mycosis Fungoides | Sezary Syndrome | Stage IB Mycosis Fungoides and Sezary Syndrome AJCC v8 | Stage II Mycosis Fungoides and Sezary Syndrome AJCC v8 | Stage IIA Mycosis Fungoides and Sezary Syndrome AJCC v8 | Stage IIB Mycosis Fungoides and Sezary Syndrome AJCC v8 | Stage III Mycosis Fungoides... and other conditions

United States
Burke Medical Research Institute

Active, not recruiting

Home Based Tele-exercise for People With Chronic Neurological Impairments (Telex)

Stroke | Multiple Sclerosis | Cerebral Palsy | Parkinson Disease | Spinal Cord Injuries | Neurologic Disorder | Hemiplegia | Hemiparesis | Friedreich Ataxia | Trauma, Brain | Transverse Myelitis

United States
Harran University
Hasan Kalyoncu University

Not yet recruiting

The Effect of Probiotics Added to the Mother's Diet on Preterm Babies

Necrotizing Enterocolitis | Breast Milk Expression | Preterm | Late-Onset Neonatal Sepsis
Rocket Pharmaceuticals Inc.

Recruiting

A Multi-Center, Open Label Gene Therapy Study of RP-A501 in Male Patients With Danon Disease

Danon Disease

United States
University of Michigan

Recruiting

A Pilot Randomized Controlled Trial: CoINTEGRATE (CoINTEGRATE)

Multiple Sclerosis | Neurocognitive Disorders | Cognitive Dysfunction | Traumatic Brain Injury | Mild Cognitive Impairment

United States
Brigham and Women's Hospital
Agency for Healthcare Research and Quality (AHRQ)

Recruiting

Advancing Health Information Exchange (HIE) During Inter-hospital Transfer (IHT) to Improve Patient Outcomes

Gastrointestinal Diseases | Heart Failure | Infections | Urologic Diseases | Shock | Hematologic Diseases | Critical Illness | Rheumatic Diseases | Asthma | Renal Failure | Neurologic Disorder | COPD Exacerbation | Cardiac Event | Oncology Problem | Arrythmia | Renal Disease

United States
Murdoch Childrens Research Institute
National Health and Medical Research Council, Australia; Royal Children's Hospital and other collaborators

Recruiting

Generation Victoria Cohort 2020s: A Statewide Longitudinal Cohort Study of Victorian Children and Their Parents (GenV)

Communicable Diseases | Quality of Life | Inflammation | Obesity | Congenital Abnormalities | Genetics | Healthy Aging | Child Development | Diet | Mental Health | Disability | Injuries | Cognition | Child Health | Environmental Exposure | Noncommunicable Diseases | Physical Fitness | Intergenerational Relations | Social Determinants... and other conditions

Australia
Children's Hospital Medical Center, Cincinnati

Not yet recruiting

Use of NGAL for Fluid Dosing and CRRT Initiation in Pediatric and Neonatal AKI (Taking Focus 2)

Acute Kidney Injury | Acute Kidney Injury Due to Sepsis | Neonatal Sepsis

United States
Helsinki University Central Hospital

Recruiting

Patient-reported Outcome Measures (PROMs) in Patients With Bodily Stress Syndrome: Protocol for a Prospective Cohort Study (SYMPA)

Fatigue | Irritable Bowel Syndrome | Fibromyalgia | Dysphagia | Chronic Fatigue Syndrome | Somatic Symptom | Exhaustion; Syndrome

Finland
Chinese University of Hong Kong

Recruiting

The Microbiome of Oesophageal Squamous Cell Carcinoma

Esophageal Cancer | Microbial Colonization

Hong Kong
Novartis Pharmaceuticals

Terminated

Basket Study to Assess Efficacy, Safety and PK of Iptacopan (LNP023) in Autoimmune Benign Hematological Disorders

Immune Thrombocytopenia (ITP) | Cold Agglutinin Disease (CAD)

United States, Spain, Germany, Korea, Republic of, United Kingdom, Italy
PDS Biotechnology Corp.
Merck Sharp & Dohme LLC

Active, not recruiting

Study of PDS0101 and Pembrolizumab Combination I/O in Subjects With HPV16 + Recurrent and/or Metastatic HNSCC (VERSATILE002)

HPV Positive Oropharyngeal Squamous Cell Carcinoma | Recurrent Head and Neck Cancer | Metastatic Head and Neck Cancer | Neoplasms, Head and Neck

United States, Puerto Rico, Ireland, United Kingdom
University of Maryland, College Park
National Institute on Drug Abuse (NIDA); Medical Research Council, South Africa

Active, not recruiting

Siyakhana Peer: Evaluating a Peer Recovery Coach Model to Reduce Substance Use Stigma in South African HIV Care

Substance-Related Disorders | HIV | Substance Use | Substance Use Disorders | Treatment Adherence | Treatment Adherence and Compliance | Stigmatization | Delivery of Health Care | Stigma, Social | Attitude of Health Personnel | Community Health Workers | Health Personnel | Health Personnel Attitude | Health Care Seeking... and other conditions

South Africa
Zagazig University

Completed

High Dose Vitamin D Supplementation in Children With Sickle Cell Disease

Vitamin D Deficiency | Sickle Cell Disease | Bone Mineral Density | Health Related Quality of Life | Hand Grip Strength

Egypt
Pfizer
Arena is a wholly owned subsidiary of Pfizer

Terminated

A Study to Assess the Effect of Oral Temanogrel on Digital Blood Flow in Adult Participants With Raynaud's Phenomenon Secondary to Systemic Sclerosis

Raynaud's Phenomenon Secondary to Systemic Sclerosis

United Kingdom, United States
Weill Medical College of Cornell University
Patient-Centered Outcomes Research Institute

Completed

Comparative Effectiveness of Telemedicine in Primary Care

Hypertension | Diabetes | Asthma | Congestive Heart Failure | Chronic Obstructive Pulmonary Disease (COPD

United States
University of Aarhus
Center for Clinical Research and Prevention

Completed

Welfare Benefits in Functional Somatic Disorders

Irritable Bowel Syndrome | Fibromyalgia | Somatoform Disorders | Medically Unexplained Symptoms | Chronic Fatigue Syndrome | Bodily Distress Syndrome | Medically Unexplained Syndrome

Clinical Trials on Immunization; Infection

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