Clinical Trials on Immuno-Deficiency in United Kingdom

Total 25862 results

Gilead Sciences

Active, not recruiting

Study to Evaluate the Pharmacokinetics, Safety, and Antiviral Activity of the Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide (E/C/F/TAF) Single Tablet Regimen (STR) in HIV-1 Infected Antiretroviral Treatment-Naive Adolescents and Virologically Suppressed Children

HIV Infections | Acquired Immune Deficiency Syndrome (AIDS)

United States, Thailand, Uganda, South Africa, Zimbabwe
St. Jude Children's Research Hospital
National Heart, Lung, and Blood Institute (NHLBI); Doris Duke Charitable Foundation

Completed

Peripheral Blood Stem Cells Obtained From Normal Volunteers for Studying Retroviral Vector Mediated Gene Transfer Into Primitive Hematopoietic Cells and Vector Mediated Transgene Expression in Mature Hematopoietic Lineages

Immunodeficiency

United States
Stockton University
Nova Southeastern University

Completed

The Impact of Exercise on Stress, Fatigue, and Quality of Life in Individuals With Primary Immunodeficiency Disease

Common Variable Immunodeficiency | Hypergammaglobulinemia | Primary Immune Deficiency Disorder | Specific Antibody Deficiency

United States
ViiV Healthcare
GlaxoSmithKline

Completed

Prospective Epidemiological Study Of The Prevalence Of HLA-B*5701

Infection, Human Immunodeficiency Virus

United Kingdom
University of Colorado, Denver

Terminated

Immunoparalysis in Acute Kidney Injury After Cardiac Surgery

Acute Kidney Injury | Immune Deficiency

United States
National Institute of Allergy and Infectious Diseases...

Recruiting

Sample Collection for Systems Evaluation of Patients With Unknown or Incompletely Characterized Immune Defects

Immunodeficiency

United States
National Cancer Institute (NCI)

Completed

Studies of the Immune Response in Normal Subjects and Patients With Disorders of the Immune System

Neoplasms | Immunologic Deficiency Syndromes

United States
Grifols Therapeutics LLC

Completed

Alpha-1-Antitrypsin (AAT) To Treat Emphysema In AAT-Deficient Patients (EXACTLE)

Alpha 1-Antitrypsin Deficiency

Denmark, Sweden, United Kingdom
Northumbria University
Bayer

Completed

Efficacy Evaluation of 16 Weeks' Dietary Supplementation With Iron Bis-glycinate Plus Vitamin C on Cognitive Function, Subjective Mood, Fatigue, Health and Well-being

Cognitive Function and Mood | Non-anaemic Iron Deficiency

United Kingdom
Rocket Pharmaceuticals Inc.
California Institute for Regenerative Medicine (CIRM)

Completed

A Clinical Trial to Evaluate the Safety and Efficacy of RP-L201 in Subjects With Leukocyte Adhesion Deficiency-I

Leukocyte Adhesion Defect - Type I

Spain, United States, United Kingdom
Royal Centre for Defence Medicine
Liverpool John Moores University; Leeds Beckett University

Unknown

Influence of Military Preventive Policy for reCruit Training on COVID-19 Seroconversion (IMPACTCOVID)

Covid19 | Vitamin D Deficiency | SARS-CoV Infection | Acute Respiratory Tract Infection

United Kingdom
Wake Forest University Health Sciences

Terminated

Donor Lymphocyte Infusion After Alternative Donor Transplantation

Immunodeficiency

United States
Arrowhead Pharmaceuticals

Terminated

A Study of ARC-AAT in Healthy Volunteer Subjects and Patients With Alpha-1 Antitrypsin Deficiency (AATD)

Alpha-1 Antitrypsin Deficiency

Australia, Netherlands, Germany, United Kingdom
Octapharma

Completed

A Study to Compare Quality of Life and Satisfaction in Primary Immunodeficient Patients Treated With Subcutaneous Injections of Gammanorm® 165 mg/mL Administered With Two Different Delivery Devices: Injections Using Pump or Rapid Push

Primary Immunodeficiency

United Kingdom, Australia, Germany, Italy
Imperial College London

Withdrawn

Determining the Reproductive Health of Men Post-COVID-19 Infection

Infertility, Male | Testosterone Deficiency

United Kingdom
BriovaRx Infusion Services

Terminated

Gamma Globulin Observations and Outcomes Database for Patients With Primary Immunodeficiency Disease (GOOD-SHEPARD-PI)

Primary Immune Deficiency Disorder

United States
University of California, Los Angeles

Completed

Vitamin D in HIV-Infected Patients on HAART

Vitamin D Deficiency | HIV

United States
AUG Therapeutics

Recruiting

An Extension Study Assessing the Safety and Efficacy of AVTX-803 in Subjects With Leukocyte Adhesion Deficiency Type II

Leukocyte Adhesion Deficiency

United States
Institute of Cancer Research, United Kingdom
Cancer Research UK; National Institute for Health Research, United Kingdom

Completed

Magnetic Resonance Imaging Screening in Li Fraumeni Syndrome (SIGNIFY)

Li-Fraumeni Syndrome

United Kingdom
Yale University
Bristol-Myers Squibb; Merck Sharp & Dohme LLC

Completed

Pilot Study of a Raltegravir Based NRTI Sparing Regimen

HIV Infections | Human Immunodeficiency Virus | AIDS | Acquired Immune Deficiency Syndrome

United States
Keesler Air Force Base Medical Center

Completed

Autoantibodies to Gastric Parietal Cells in Rheumatoid Arthritis Patients

Vitamin B12 Deficiency

United States
Children's Hospital of Philadelphia

Completed

CHP 834 Unrelated and Partially Matched Related Donor Peripheral Stem Cell Transportation for T and B Cell Depletion (CliniMACs)

Immunodeficiencies

United States
Medical College of Wisconsin
Baxter Healthcare Corporation

Withdrawn

Novel Testing Procedures

Immunodeficiencies

United States
Kirby Institute
Chelsea and Westminster NHS Foundation Trust

Completed

The Intensive Pharmacokinetics Sub-study of Encore1 (ENCORE1-PK)

HIV Infection

Argentina, South Africa, Thailand, United Kingdom
Bristol-Myers Squibb

Completed

Drug Interaction Study of Famotidine and Atazanavir With Ritonavir in HIV-Infected Patients

HIV Infections

United States, United Kingdom
AUG Therapeutics

Recruiting

A Study to Evaluate Efficacy and Safety of AVTX-803 in Patients With Leukocyte Adhesion Deficiency Type II

Leukocyte Adhesion Deficiency

United States
CSL Behring

Completed

Study of Subcutaneous Immune Globulin in Patients Requiring IgG Replacement Therapy (EU Extension Study)

Primary Immunodeficiency (PID)

Poland, Germany, France, Romania, Spain, Sweden, Switzerland, United Kingdom
Duke University
National Institute of Allergy and Infectious Diseases (NIAID); University of... and other collaborators

Recruiting

COVID-19 Vaccine Responses in PIDD Subjects

Common Variable Immunodeficiency | X-linked Agammaglobulinemia | Primary Immune Deficiency | Primary Antibody Deficiencies | CVID | XLA | Secondary Hypogammaglobulinemia

United States
Arcturus Therapeutics, Inc.

Recruiting

Study for Adolescent and Adult Participants With Ornithine Transcarbamylase Deficiency to Evaluate Safety and Tolerability of ARCT-810

OTC Deficiency | Ornithine Transcarbamylase Deficiency | OTCD

Spain, Belgium, United Kingdom, Sweden
Michele Staton
National Institute on Drug Abuse (NIDA)

Completed

Brief Intervention for Rural Women at High Risk for HIV/HCV (WISH)

Hepatitis C | Drug Abuse | Acquired Immune Deficiency Syndrome Virus

United States
Texas A&M University

Unknown

Nutrition, Vision, and Cognition in Sport Study: Beef (IONSport:Beef)

Cognitive Change | Nutritional Anemia | Diet, Healthy | Nutrient Deficiency | Diet; Deficiency | Visual Spatial Processing | Dietary Deficiency | Dietary B12 Deficiency | Dietary Zinc Deficiency | Dietary Vitamin B12 Deficiency Anemia | Dietary Deficiency of Selenium and Vitamin E

United States
Pharvaris Netherlands B.V.

Active, not recruiting

Dose-ranging Study of Oral PHA-022121 for Prophylaxis Against Angioedema Attacks in Patients With Hereditary Angioedema Type I or Type II (HAE CHAPTER-1)

Hereditary Angioedema | Hereditary Angioedema Type I | Hereditary Angioedema Type II | Hereditary Angioedema Types I and II | Hereditary Angioedema Attack | Hereditary Angioedema With C1 Esterase Inhibitor Deficiency | Hereditary Angioedema - Type 1 | Hereditary Angioedema - Type 2 | C1 Esterase Inhibitor... and other conditions

United States, Poland, Germany, Austria, Bulgaria, Canada, Ireland, Italy, United Kingdom
Emory University

Terminated

Effect of High-Dose Vitamin D3 in Smokers and Non-Smokers With and Without HIV

HIV/AIDS | Vitamin D Deficiency | Smoker Lung

United States
Great Ormond Street Hospital for Children NHS Foundation...

Recruiting

Improving Phosphate Control in Children With CKD (IMPACT)

Chronic Kidney Diseases | Hyperphosphatemia | Chronic Kidney Disease-Mineral and Bone Disorder | Pediatric Kidney Disease | CKD-MBD

United Kingdom
Rockefeller University

Terminated

Impact of Metabolic Syndrome on Flu Vaccine Efficacy

Metabolic Syndrome | Immune Deficiency

United States
Indiana University

Withdrawn

Vitamin D Deficiency Causes Immune Dysfunction and Enables or Perpetuates the Development of Rheumatoid Arthritis

Arthritis, Rheumatoid | Vitamin D Deficiency

United States
ProofPilot
Joovv

Unknown

Use of Infrared Photomodulation for Hormonal Balance (Joovvin' for Hormonal Health)

Testosterone Deficiency | Estrogen Deficiency

United States
HealthCore-NERI
Bayer; Besins Healthcare

Completed

Registry of Hypogonadism in Men (RHyMe)

Male Hypogonadism | Testosterone Deficiency | Androgen Deficiency

Italy, United Kingdom, Spain, Netherlands, Germany, Sweden
CSL Behring

Terminated

Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Subcutaneous CSL730 in Healthy Adult Subjects

Immune Complex-mediated Autoimmune Diseases

United Kingdom
Sourse
Citruslabs

Active, not recruiting

An Exploratory Investigation of a B12 Vitamin to Increase Energy and Focus

Mood | Energy Supply; Deficiency | B12 Deficiency Vitamin

United States
New York Medical College
Children's Hospital of Philadelphia; Washington University School of Medicine; University of California, Los Angeles and other collaborators

Recruiting

EBV-specific Cytotoxic T-lymphocytes (CTLs) for Refractory EBV Infection

Epstein-Barr Virus Infections | Primary Immune Deficiency Disorder

United States
rEVO Biologics

Completed

Assess Incidence of Deep Vein Thrombosis(DVT)Following Administration of Recombinant Human Antithrombin (rhAT) to Hereditary Antithrombin(AT) Deficient Patients in High Risk Situations. (rhAT)

Antithrombin Deficiency, Congenital

France, United Kingdom, Germany, United States, Sweden, Italy
Octapharma

Recruiting

Study to Evaluate the Pharmacokinetics, Efficacy, Tolerability, and Safety of Subcutaneous Human Immunoglobulin (Newnorm) in Patients With Primary Immunodeficiency Diseases

Primary Immune Deficiency

United States, Germany, Italy, Poland, Slovakia, Ukraine, Hungary
Shield Therapeutics

Recruiting

Evaluate the Safety and Efficacy of Ferric Maltol Oral Suspension vs. Ferrous Sulfate Oral Liquid in Children and Adolescents Aged 2 to 17 Years With Iron-deficiency Anaemia, With a Single Arm Study in Infants Aged 1 Month to Less Than 2 Years (FORTIS)

Iron-deficiency | Anemia

United States, United Kingdom, Puerto Rico
Vifor Pharma
ICON Clinical Research; American Regent, Inc.

Completed

Ferric Carboxymaltose (FCM) Assessment in Subjects With Iron Deficiency Anaemia and Non-dialysis-dependent Chronic Kidney Disease (NDD-CKD) (FIND-CKD)

Chronic Kidney Disease | Iron Deficiency Anaemia

United Kingdom, United States, Australia, Austria, Belgium, Czech Republic, Denmark, France, Germany, Greece, Italy, Netherlands, Norway, Poland, Portugal, Romania, Spain, Sweden, Turkey
National Institute of Arthritis and Musculoskeletal...

Terminated

Genetic Basis of Primary Immunodeficiencies

Immunologic Deficiency Syndrome

United States
Texas Tech University Health Sciences Center

Completed

Effect of Vitamin D Replacement on Insulin Sensitivity

Insulin Sensitivity

United States
University Hospital Southampton NHS Foundation...
University of Southampton

Completed

Prebiotics and Immune Function in Middle Aged Humans

Immune Function

United Kingdom
Pfizer

Completed

Azithromycin in the Treatment of Cryptosporidiosis in Patients With Acquired Immune Deficiency Syndrome (AIDS): A Randomized, Multi-Center, Placebo-Controlled, Double-Blind Study

HIV Infections | Cryptosporidiosis

United States
Medialis Ltd.
Metabolic Support UK

Completed

Retrospective and Prospective Disease Progression and Quality of Life in XLH

X-linked Hypophosphatemia (XLH)

United Kingdom

Clinical Trials on Immuno-Deficiency in United Kingdom

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