Clinical Trials on Immuno-Deficiency in United Kingdom

Total 25865 results

Alexion Pharmaceuticals

Terminated

Clinical Study In Infants With Rapidly Progressive Lysosomal Acid Lipase Deficiency

Lysosomal Acid Lipase Deficiency

United Kingdom, Finland, United States, Italy
Imperial College London

Enrolling by invitation

Colonoscopy Check-up in People With Lynch Syndrome

Lynch Syndrome

United Kingdom
Arrowhead Regional Medical Center

Recruiting

Intravenous Iron Versus Oral Iron for the Treatment of Iron Deficiency Anemia (IDA)

Iron Deficiency Anemia of Pregnancy

United States
University of Colorado, Denver

Completed

Enhancing Treatment of Iron Deficiency and Iron Deficiency Anemia With an Antioxidant, Vitamin E

Iron Deficiency Anemia | Iron Deficiency

United States
University of Edinburgh
Allergy UK

Completed

Allergy UK Research and Development Nurse Project (ALLUKN)

Allergy

United Kingdom
University of Nottingham

Completed

Test@Work Study: Evaluation of Attitudes and Uptake Within Employee Health Checks in the Construction Industry (Test@Work)

HIV

United Kingdom
GlaxoSmithKline
Quotient Clinical

Completed

A Study to Compare the Pharmacokinetics (PK) of GSK2982772 Following Administration of Different Modified Release (MR) Formulations in Capsule and MR Tablet Formulations Relative to an Immediate Release (IR) Tablet Formulation and to Check the PK of MR Formulation in Capsule Following Repeat Doses

Autoimmune Diseases

United Kingdom
GlaxoSmithKline
Quotient Sciences

Completed

A Study to Investigate the Pharmacokinetics (PK) of Modified Release (MR) Prototype Coated Tablet Formulations of GSK2982772

Autoimmune Diseases

United Kingdom
St Stephens Aids Trust
ViiV Healthcare

Completed

The Pharmacokinetics of Dolutegravir, Darunavir/Cobocistat When Co-administered in Healthy Volunteers (SSAT073)

HIV

United Kingdom
St Stephens Aids Trust
Bristol-Myers Squibb

Terminated

Pharmacokinetic Effect of Evotaz/Microgynon Co-administration

HIV

United Kingdom
GlaxoSmithKline

Completed

A Single and Repeat Dose PK/PD Study to Characterise Biomarker Response in Healthy Subjects Treated With Azithromycin

Autoimmune Diseases

United Kingdom
St Stephens Aids Trust
Merck Sharp & Dohme LLC

Completed

Renal Integrase Study

HIV

United Kingdom
St Stephens Aids Trust

Completed

A Study to Assess Cerebrospinal Fluid INflammatory Markers After Addition of Maraviroc to MONotherapy Darunavir/Ritonavir - The CINAMMON Study (CINAMMON)

HIV

United Kingdom
Helen Reynolds

Completed

The Effect of Antacids and Multivitamins on Raltegravir

HIV

United Kingdom
PX'Therapeutics
European Commission

Completed

Safety & Immunogenicity of Immunisations With EN41-UGR7C HIV Vaccine

- HIV

United Kingdom
St Stephens Aids Trust

Completed

Pilot Study Switching Individuals Receiving EFV With Continuing Central Nervous System Toxicity to TMC125

HIV

United Kingdom
United States Army Research Institute of Environmental...

Recruiting

Effects of Varying Energy Deficits on Protein Turnover at Rest and Carbohydrate Oxidation During Steady-state Exercise

Stress, Physiological | Energy Supply; Deficiency | Energy Supply; Deficiency, Severe

United States
University of Nottingham

Unknown

Immune Function in Patients With Obstructive Jaundice

Obstructive Jaundice | Immune Tolerance | Disease as Reason for ERCP | Immune Dysfunction

United Kingdom
GlaxoSmithKline

Completed

A Safety and Pharmacokinetic (PK) Study of GSK2982772 in Healthy Subjects

Autoimmune Diseases

United Kingdom
University of Oxford

Completed

A Study to Assess Safety and Immunogenicity of Conserved Mosaic HIV-1 Vaccines

HIV

United Kingdom
Société des Produits Nestlé (SPN)

Terminated

Acceptability and Tolerance Study of an Amino Acid Formula With HMOs

Infant Development

United Kingdom
Imperial College London

Withdrawn

The Effect of Eating Frequency on Blood Pressure

Blood Pressure

United Kingdom
The Leeds Teaching Hospitals NHS Trust

Completed

Penicillin Allergy De-Labelling in Elective Surgical Patients (PADLES) (PADLES)

Allergy

United Kingdom
St Stephens Aids Trust
ViiV Healthcare

Completed

SSAT064: Pharmacokinetics of Abacavir/Lamivudine/Dolutegravir in HIV Patients of 60 Years and Over

HIV

United Kingdom
St. Stephens Clinical Research

Completed

RIFT: Effect of Rifampicin on Plasma PK of FTC, TAF and Intracellular TFV-DP & FTC-TP (RIFT)

HIV

United Kingdom
St Stephens Aids Trust
Mylan Inc.

Completed

SSAT063- Pharmacokinetics of Efavirenz 400 mg Once Daily During Pregnancy in HIV-1 Infected Women

HIV

United Kingdom
GlaxoSmithKline

Completed

Single Ascending Doses Study of Anti- Interleukin-7 Receptor α Monoclonal Antibody (GSK2618960) in Healthy Volunteers

Autoimmune Diseases

United Kingdom
St Stephens Aids Trust
University of Liverpool

Suspended

PK of Efavirenz & Lopinavir Nano-formulations in Healthy Volunteers

HIV

United Kingdom
St Stephens Aids Trust
ViiV Healthcare

Completed

SSAT061: PK of DTG and EVT/COBI in Healthy Volunteers

HIV

United Kingdom
St Stephens Aids Trust
ViiV Healthcare

Unknown

Efavirenz to Dolutegravir Switch in Patients With CNS Toxicity

HIV

United Kingdom
Imperial College London
Janssen-Cilag Ltd.

Completed

The Rilpivirine Cerebrospinal-fluid (CSF) Study

HIV

United Kingdom
St Stephens Aids Trust

Terminated

NNRTI/PI Toxicity Switch to Darunavir Study

HIV

United Kingdom
Northwestern University

Completed

EHR-based Patient Identification and Panel Management of Patients With Iron Deficiency Anemia

Iron-deficiency Anemia

United States
University of Oxford

Completed

Safety and Immunogenicity of Candidate HIV Vaccines Given Sequentially

Healthy

United Kingdom
Public Health England

Withdrawn

Ethnicity Data in HIV Positive Men Who Have Sex With Men

HIV

United Kingdom
Imperial College London

Completed

The Safety, Pharmacokinetic Profile and Efficacy of Raltegravir in HIV-infected Patients at Least 60 Years of Age

HIV

United Kingdom
Imperial College London

Completed

The Maraviroc Darunavir/Ritonavir Once Daily Pharmacokinetic Study

HIV

United Kingdom
Imperial College London
Medical Research Council

Completed

Safety and Immunogenicity of HIV DNA-C CN54ENV and Recombinant HIV CN54gp140 Vaccines in Healthy Volunteers

HIV

United Kingdom
St Stephens Aids Trust

Completed

A Pilot Study to Assess the Feasibility of Switching, Individuals Receiving Atripla With Continuing Central Nervous System (CNS) Toxicity, to a Fixed Dose Combination of Tenofovir/Emtricitabine/Rilpivirine

HIV

United Kingdom
St Stephens Aids Trust

Completed

A Phase IV, Open-label Single-arm Study Investigating the Pharmacokinetics and Pharmacodynamics of the Antiretroviral Combination of Rilpivirine and Ritonavirboosted Darunavir in Therapy-naive HIV-1 Infected Patients.

HIV

United Kingdom
MRC [ycm]

Completed

Pre-exposure Option for Reducing HIV in the UK.(PROUD) (PROUD)

HIV

United Kingdom
St Stephens Aids Trust
Bristol-Myers Squibb

Completed

SSAT067 PK of Atazanavir/Cobicistat and Darunavir/Cobicistat

HIV

United Kingdom
St Stephens Aids Trust

Completed

Pharmacokinetics of Tenofovir and Tenofovir-diphosphate, Emtricitabine and Emtricitabine-triphosphate, and Rilpivirine Once Daily Over 14 Days Following Drug Intake Cessation in Healthy Volunteers

HIV

United Kingdom
Chelsea and Westminster NHS Foundation Trust
King's College Hospital NHS Trust; Public Health England; Department of Health... and other collaborators

Completed

HIV Testing in Non-traditional Settings Study (HINTS)

HIV

United Kingdom
St Stephens Aids Trust

Completed

Raltegravir and Ezetimibe PK Study

HIV

United Kingdom
St Stephens Aids Trust

Completed

Abacavir Pharmacokinetic Study in the Absence/Presence of Darunavir/Ritonavir or Raltegravir in HIV-infected Subjects

HIV

United Kingdom
University of Alabama at Birmingham

Completed

Assessment of Influence of Vitamin D on Insulin Secretion and Sensitivity in Obese Teenage Girls

Obesity | Vitamin D Deficiency | Insulin Resistance | Insulin Sensitivity

United States
Alexion Pharmaceuticals

Completed

Safety, Tolerability and Pharmacokinetics of SBC-102 (Sebelipase Alfa) in Adult Participants With Lysosomal Acid Lipase Deficiency

Lysosomal Acid Lipase Deficiency | Cholesterol Ester Storage Disease(CESD) | LAL-Deficiency

France, United States, United Kingdom, Czechia
American Regent, Inc.

Completed

Observational Study on the Use of IV (Intravenous) Iron Therapy Among Subjects With Iron Deficiency Anemia

Iron Deficiency Anemia (IDA)

United States
Ratiopharm GmbH

Completed

Multiple Dose BE Study With Nevirapine 400mg PR Tablets

HIV-1

United Kingdom

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