Clinical Trials on Immunology

Total 5350 results

National Institute of Allergy and Infectious Diseases...

Terminated

Biochemical Response to Interferon-Gamma in Subjects With Specific Gene Mutation in Chronic Granulomatous Disease

IFN-Gamma Therapy | CGD Gene Mutation | CGD Response to IFNg | CGD - Chronic Granulomatous Disease | Immunodeficiency Disease

United States
Soma Jyonouchi
Baylor College of Medicine

Completed

Interleukin-2 Treatment for Wiskott-Aldrich Syndrome (WAS)

X-linked Thrombocytopenia | Wiskott-Aldrich Syndrome (WAS)

United States
George Washington University

Completed

The Effect of HIV Tat Protein on HCV Replication in an In-vitro Model System

Hepatitis C, Chronic | Human Immunodeficiency Virus (HIV)

United States
Johns Hopkins Bloomberg School of Public Health
Johns Hopkins University; National Institute of Allergy and Infectious Diseases... and other collaborators

Completed

Studies of the Ocular Complications of AIDS (SOCA)--Cytomegalovirus Retinitis Retreatment Trial (CRRT) (CRRT)

HIV Infections | Acquired Immunodeficiency Syndrome | Cytomegalovirus Retinitis
National Institute of Allergy and Infectious Diseases...

Terminated

Treatment for Growth Failure in Patients With X-Linked Severe Combined Immunodeficiency: Phase 2 Study of Insulin-Like Growth Factor-1

Growth Failure | X-linked Severe Combined Immunodeficiency (XSCID) | Growth Hormone Resistence

United States
Johns Hopkins University
National Institutes of Health (NIH)

Completed

Effects of Endocrine Health on Mental Performance of Men and Women Using Drugs

Human Immunodeficiency Virus Positive or Negative

United States
Johann Wolfgang Goethe University Hospital

Completed

Body Composition and Hormonal Status in Ataxia Telangiectasia

Ataxia Telangiectasia
Gilead Sciences

Completed

Efficacy and Safety of Sofosbuvir Plus Ribavirin in Chronic Genotype 1, 2 and 3 Hepatitis C Virus (HCV) and Human Immunodeficiency Virus (HIV) Co-infected Adults

Hepatitis C | Human Immunodeficiency Virus

United States, Puerto Rico
National Institute of Allergy and Infectious Diseases...
Warner Lambert - Parke Davis

Completed

Two-Stage Tuberculin (PPD) Skin Testing in Individuals With Human Immunodeficiency Virus (HIV) Infection

HIV Infections | Tuberculosis

United States
Holdsworth House Medical Practice

Completed

The Prevalence of Neurocognitive Disorder in a Primary Care-based HIV Cohort Compared to a HIV-negative Control Cohort - (CNS HAND)

HIV-1-Associated Cognitive Motor Complex
ViiV Healthcare
GlaxoSmithKline; Shionogi

Completed

A Phase 1, Open Label, Placebo-Controlled Study to Evaluate the Effect of GSK1349572 on Iohexol and Para-Aminohippurate Clearance in Healthy Subjects

Infections, Human Immunodeficiency Virus and Tuberculosis

United States
Stanford University
Ministry of Health, Rwanda

Completed

HIV Prevention and Care of Psychological Trauma in Vulnerable Rwandan Youth

Acquired Immunodeficiency Syndrome | Stress Disorders, Post-Traumatic

United States, Rwanda
Sheba Medical Center

Unknown

Immunogenicity of Pneumococcal Vaccines in Ataxia-telangiectasia Patients

Ataxia Telangiectasia

Israel
National Institute of Allergy and Infectious Diseases...

Completed

Pioglitazone to Treat Fatty Liver in People With HIV Infection

HIV Infections | Insulin Resistance | Hepatic Steatosis

United States
Tuberculosis Research Centre, India
Indian Council of Medical Research; National AIDS Control Organisation

Unknown

Safety and Efficacy of Two Once Daily Anti Retroviral Treatment Regimens Along With Anti-tuberculosis Treatment

Tuberculosis | Human Immunodeficiency Virus Infections

India
National Eye Institute (NEI)

Completed

Ganciclovir Implant Study for Cytomegalovirus Retinitis

HIV Infections | Acquired Immunodeficiency Syndrome | Cytomegalovirus Retinitis
Sheba Medical Center

Unknown

The Validity of Forced Expiratory Maneuvers in Ataxia Telangiectasia Studied Longitudinally

Ataxia Telangiectasia

Israel
National Institute of Allergy and Infectious Diseases...

Completed

Voriconazole vs. Amphotericin B in the Treatment of Invasive Aspergillosis

HIV Infections | Acquired Immunodeficiency Syndrome | Immunologic Deficiency Syndromes | Neutropenia | Aspergillosis

United States
National Eye Institute (NEI)

Completed

Efficacy of Elevated CD4 Counts on CMV Retinitis

Acquired Immunodeficiency Syndrome | Cytomegalovirus Retinitis

United States
Aalborg University Hospital

Unknown

Hepatitis Vaccination in HIV Infection: Role of Adjuvant Interleukin-2 (HEPVACHIV)

HIV Infections | Hepatitis B | Hepatitis A

Denmark
French National Agency for Research on AIDS and...

Terminated

Liver Transplantation in Patients With Hepatitis C Virus (HCV) and Human Immunodeficiency Virus (HIV) Coinfection

HIV Infections | Hepatitis C

France
Sandoz

Completed

A Phase I/II Trial to Assess the Safety and Tolerance of Escalating Doses of a Human Anti-Cytomegalovirus Monoclonal Antibody (SDZ MSL-109) in Patients With the Acquired Immunodeficiency Syndrome and CMV Retinitis

HIV Infections | Cytomegalovirus Retinitis

United States
Glaxo Wellcome

Completed

A Study of Azidothymidine (AZT) in the Treatment of HIV Infection in Patients Receiving a Bone Marrow Transplant

HIV Infections | Lymphoma, Non-Hodgkin

United States
National Center for Research Resources (NCRR)
Northwestern University

Completed

Phase II Randomized Study of Cidofovir for Peripheral Cytomegalovirus Retinitis

Acquired Immunodeficiency Syndrome | Cytomegalovirus Retinitis
University of California, San Francisco
National Institute of Allergy and Infectious Diseases (NIAID); University Hospital... and other collaborators

Not yet recruiting

Pragmatic Use of Next-generation Sequencing for Management of Drug-resistant Tuberculosis (TSELiOT)

Drug-resistant Tuberculosis | Cost-Benefit Analysis | HIV Coinfection

South Africa
Emory University

Recruiting

Low Dose Naltrexone for Pain in Patients With HIV

Human Immunodeficiency Virus | Chronic Neuropathic Pain

United States
Assistance Publique - Hôpitaux de Paris

Recruiting

Clinico-biological Characterization and Survival of Patients With Adult T-cell Leukemia / Lymphoma (ATL) and Patients Chronically Infected With the HTLV-1 Virus (HTLV-OBS) (HTLV-OBS)

HTLV-1 Infection | Lymphoproliferation Induced by HTLV-1 | HTLV-1 Adult T-cell Lymphoma / Leukemia

France
Yale University
National Institute on Drug Abuse (NIDA); Universiti Sains Malaysia

Recruiting

Implementation of STTR Strategies Among People Who Inject Drugs in Malaysia

HIV Seropositivity | Opioid-use Disorder

Malaysia
University of Maryland, Baltimore
ViiV Healthcare

Completed

Maraviroc Efficacy for Hepatitis C (MAVERIC)

Hepatitis C | Human Immunodeficiency Virus

United States
University Hospital, Montpellier

Terminated

The Role of the Coagulation Pathways in Recurrent Angioedema (Angiocoag)

Chronic Spotaneous Urticaria, Idiopathic Non Histaminergic Angioderma, Hereditary Angioedema With C1 Inhibitor Deficiency

France
University of Houston
National Institute on Drug Abuse (NIDA)

Completed

Project PRIDE (Promoting Resilience In Discriminatory Environments)

Depression | Anxiety | Substance Use Disorders | Sexually Transmitted Infections | Human Immunodeficiency Virus

United States
Johann Wolfgang Goethe University Hospital

Completed

Oxidative Stress, Low Grade Inflammation, Tissue Breakdown and Biomarkers in Cerebrospinal Fluid of A-T

Ataxia Telangiectasia

Germany
National Institute of Mental Health (NIMH)

Terminated

Mild Neurocognitive Disorder in HIV Infection of the Brain

HIV-Associated Cognitive Motor Complex

United States
Erasmus Medical Center

Completed

Dutch Acute HCV in HIV Study (DAHHS-2): Grazoprevir/Elbasvir for Acute HCV (DAHHS-2)

Hepatitis C | Human Immunodeficiency Virus | Acute Hepatitis C

Netherlands, Belgium
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Lenalidomide and Ofatumumab in Treating Participants With Previously Treated Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

Fatigue | Thrombocytopenia | Fever | Chronic Lymphocytic Leukemia | Lymphadenopathy | Small Lymphocytic Lymphoma | Hypogammaglobulinemia | Lymphocytosis | Night Sweats | Paraproteinemia

United States
Drugs for Neglected Diseases
London School of Hygiene and Tropical Medicine; Institute of Tropical Medicine... and other collaborators

Completed

Efficacy Trial of Ambisome Given Alone and Ambisome Given in Combination With Miltefosine for the Treatment of VL HIV Positive Ethiopian Patients.

Visceral Leishmaniasis

Ethiopia
Icahn School of Medicine at Mount Sinai
Gilead Sciences

Completed

Outcomes in Liver Disease Patient With and Without HIV Co-infection-Sub Study 2: HCV Treatment: Health Related Quality

Hepatitis C Infection

United States
Valme University Hospital
Hospital Universitario de Canarias; Hospital Universitario Virgen Macarena; Hospital... and other collaborators

Unknown

Real-life Security and Efficacy of DAA-based Therapy in HCV/HIV-Coinfected Patients

Hepatitis C, Chronic | Human Immunodeficiency Virus

Spain
University of Witwatersrand, South Africa

Completed

Validation of Implementation of Cervical Dysplasia Treatment Modalities in HIV-Seropositive Women (VICAR2)

Cervical Intraepithelial Neoplasia

South Africa
Bayside Health

Terminated

Associations, Outcomes and Genomics of GB Virus C, Hepatitis C Virus and Human Immunodeficiency Virus Infection

HIV Infections | Hepatitis C

Australia
Saint Antoine University Hospital

Completed

Prognosis of Acute Coronary Syndrome in HIV-infected Patients

HIV Infection | Coronary Heart Disease

France
Pronova BioPharma
Aalborg University Hospital

Completed

Omacor and Cardiovascular Risk Factors in HIV Patients on HAART Treatment

Ischemic Heart Disease | Human Immunodeficiency Virus

Denmark
DBL -Institute for Health Research and Development
Danish Council for Development Research; The AIDS Foundation, Denmark; The Wedell-Wedellsborg...

Completed

Interaction Between HIV and Lymphatic Filariasis

HIV Infection | Lymphatic Filariasis
Glaxo Wellcome

Completed

A Pilot Study To Evaluate the Effect of Retrovir (Zidovudine: AZT) in the Treatment of Human Immunodeficiency Virus (HIV) Associated Dementia and Neuromuscular Diseases

HIV Infections | Neuromuscular Diseases | AIDS Dementia Complex

United States
Alkermes, Inc.

Completed

The Safety and Effectiveness of RMP-7 Plus Amphotericin B in Patients With HIV and Cryptococcal Meningitis

HIV Infections | Meningitis, Cryptococcal

United States
University of Maryland, College Park
National Institute on Drug Abuse (NIDA); University of Miami; Weill Medical College... and other collaborators

Recruiting

Project Khanya: Peer-Delivered Intervention to Improve HIV Medication Adherence and Substance Use in South Africa

Alcohol-Related Disorders | Substance Use | Drug Use | Human Immunodeficiency Virus

South Africa
Grifols Therapeutics LLC

Recruiting

A Study to Evaluate Efficacy, Safety, and Pharmacokinetics of XEMBIFY® Plus Standard Medical Treatment (SMT) Compared to Placebo Plus SMT to Prevent Infections in Participants With Hypogammaglobulinemia and Recurrent or Severe Infections Associated With B-cell Chronic Lymphocytic Leukemia

Bacterial Infections | B-cell Chronic Lymphocytic Leukemia | Hypogammaglobulinemia

United States, Bulgaria, Poland, Romania, Serbia
University of Southern California
Universidad Peruana Cayetano Heredia; AIDS Healthcare Foundation

Recruiting

Cefixime Clinical Trial

Human Immunodeficiency Virus | Syphilis

United States
Brown University
National Institute on Drug Abuse (NIDA); University of California, San Diego; Beth Israel Deaconess Medical Center and other collaborators

Recruiting

Pre-exposure Prophylaxis (PrEP) for Health (PrEP)

Substance Dependence | HIV (Human Immunodeficiency Virus)

United States
University of Turin, Italy

Recruiting

SOLFAMU Study of Nasal Brushing Collected OLFActory MUcosa Samples in the Diagnosis of Human Encephalopathies

Alzheimer Dementia | Encephalopathy | HIV-encephalopathy

Italy

Clinical Trials on Immunology

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Drug Interventions

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CROs in Moldova

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