Clinical Trials on Infants Health in Ireland

Total 1485 results

Bayer

Terminated

A Phase IIb Study to Investigate the Efficacy and Tolerability of Lower Doses Cinaciguat (25 µg/h, 10 µg/h) Given Intravenously to Patients With Acute Decompensated Chronic Congestive Heart Failure (ADHF) (COMPOSE 2)

Acute Heart Failure

Belgium, France, Argentina, United States, Austria, Mexico, Germany, Philippines, Ireland
Boston Scientific Corporation

Completed

Longitudinal Surveillance Study of the 4-SITE Lead/Header System (LSS of 4-SITE)

Primary Prevention of Sudden Cardiac Arrest | Secondary Prevention of Sudden Cardiac Arrest

United States, Canada, Australia
Gilead Sciences
Covance; ClinPhone, Inc.; Chiltern International Inc.

Completed

Aztreonam for Inhalation Solution vs Tobramycin Inhalation Solution in Patients With Cystic Fibrosis & Pseudomonas Aeruginosa

Cystic Fibrosis

Belgium, France, Germany, Italy, Netherlands, Spain, United States, Ireland, United Kingdom, Portugal, Austria, Denmark, Switzerland
Mercator MedSystems, Inc.
University of South Florida; Northwestern University; Stony Brook University; Guy... and other collaborators

Recruiting

Perivenous Dexamethasone Therapy: Examining Reduction of Inflammation After Thrombus Removal to Yield Benefit in Subacute and Chronic Iliofemoral DVT (DEXTERITY-SCI)

Iliofemoral; Thrombosis

United States, Ireland, United Kingdom
Biosense Webster, Inc.

Terminated

Atrial Fibrillation Progression Trial (ATTEST)

Atrial Fibrillation

Korea, Republic of, Germany, Belgium, Norway, Austria, Ireland, United Kingdom, Australia, Spain, Sweden, Latvia, Hungary, Italy, Poland, Russian Federation
C. R. Bard

Terminated

Study of HD Mesh Ablation System for Treatment of Paroxysmal Atrial Fibrillation (MAGELLAN)

Paroxysmal Atrial Fibrillation

United States
Angiodynamics, Inc.

Completed

SeCure Endovenous Laser Treatment Study (SeCure)

Chronic Venous Insufficiency

United States
Zoll Medical Corporation

Completed

Ambulatory Post-Syncope Arrhythmia Protection Feasibility Study (ASAP)

Syncope

United States
Charite University, Berlin, Germany

Active, not recruiting

Diagnostic Imaging Strategies for Patients With Stable Chest Pain and Intermediate Risk of Coronary Artery Disease (DISCHARGE)

Coronary Artery Disease

Austria, Hungary, Germany, United Kingdom, Romania, Czechia, Denmark, Ireland, Italy, Latvia, Lithuania, Poland, Portugal, Serbia, Spain
University of California, San Francisco
Zoll Medical Corporation

Completed

Vest Prevention of Early Sudden Death Trial and VEST Registry (VEST)

Myocardial Infarction | Ventricular Fibrillation | Ventricular Tachycardia | Ventricular Dysfunction | Sudden Death

United States, Germany, Poland
Revalesio Corporation

Completed

Safety of RNS60 in Large Vessel Occlusion Stroke Patients Undergoing Endovascular Thrombectomy (RESCUE)

Stroke, Ischemic

United States
Vertex Pharmaceuticals Incorporated

Completed

A Phase 3 Study of VX-121 Combination Therapy in Participants With Cystic Fibrosis (CF) Heterozygous for F508del and a Minimal Function Mutation (F/MF)

Cystic Fibrosis

United States, Spain, United Kingdom, New Zealand, Israel, Australia, Ireland, Germany, Sweden, Czechia, Portugal, Hungary
SoundBite Medical Solutions, Inc.

Recruiting

Treatment of Calcific Total Occlusions in Peripheral Artery Disease (CaTO-PAD)

Chronic Total Occlusion of Artery of the Extremities

United States, Austria, Germany
MedImmune LLC

Completed

A Study to Evaluate the Immunogenicity of Quadrivalent LAIV (MEDI8662) in Adults 18 to 49 Years of Age (MI-CP206)

Healthy or Stable Underlying Chronic Medical Condition

United States
ECRI bv
Siemens Healthineers AG; Pie Medical Imaging

Recruiting

Fractional Flow Reserve or 3D-Quantitative-Coronary-Angiography Based Vessel-FFR Guided Revascularization (FAST III)

Coronary Artery Disease

Germany, Ireland, Italy, Netherlands, Spain, United Kingdom, France
Northwell Health

Completed

Full Dose Heparin Vs. Prophylactic Or Intermediate Dose Heparin in High Risk COVID-19 Patients

COVID | Sars-CoV2

United States
Cordis Corporation

Completed

European (EU) Post Approval Study of the INCRAFT® AAA Stent Graft System in Subjects With Abdominal Aortic Aneurysms (INSIGHT)

Abdominal Aortic Aneurysms

United Kingdom, Netherlands, Ireland, Sweden, Germany, Italy, Spain, France
Ligand Pharmaceuticals

Completed

A Study To Evaluate The Dose-Related Efficacy and Safety of PS433540 in Subjects With Hypertension

Hypertension

United States
Boston Scientific Corporation
Pharmaceutical Research Associates; Medidata Solutions

Completed

PROMUS™ Element™ Everolimus-Eluting Coronary Stent System European Post-Approval Surveillance Study (PE-Prove)

Coronary Heart Disease

Spain, Ireland, Denmark, United Kingdom, Belgium, Germany, France, Netherlands, Italy, Austria, Hungary
Horizon Pharma USA, Inc.
Forest Laboratories

Completed

Trial of Aeroquin Versus Tobramycin Inhalation Solution (TIS) in Cystic Fibrosis (CF) Patients (TIS)

Cystic Fibrosis

United States, Ireland, United Kingdom, France, Germany, Israel
Oslo University Hospital

Recruiting

TENecteplase in Central Retinal Artery Occlusion Stuy (TenCRAOS) (TenCRAOS)

Central Retinal Artery Occlusion

Denmark, Norway, Belgium, Sweden, Finland, Ireland, Lithuania, Australia
Mercator MedSystems, Inc.
University of South Florida; Northwestern University; Stony Brook University; Guy... and other collaborators

Recruiting

Perivenous Dexamethasone Therapy: Examining Reduction of Inflammation After Thrombus Removal to Yield Benefit in Acute Femoropopliteal DVT (DEXTERITY-AFP)

Thrombosis, Deep Vein | Iliofemoral; Thrombosis

United States, Ireland, United Kingdom
VA Office of Research and Development
VA Eastern Colorado Health Care System; Atlanta VA Medical Center; VA Boston... and other collaborators

Recruiting

Breathe Easier With Tadalafil Therapy for Dyspnea in COPD-PH (BETTER COPD-PH)

Chronic Obstructive Pulmonary Disease | Pulmonary Hypertension | Dyspnea

United States
Celgene Corporation

Terminated

Prevention of Restenosis Following Revascularization

Vascular Disease, Peripheral

United States
Bristol-Myers Squibb

Completed

A Study of Mavacamten in Participants With HFpEF and Elevation of NT-proBNP With or Without Elevation of cTnT (EMBARK-HFpEF)

Heart Failure With Preserved Ejection Fraction

Canada, United States, Ireland
Swedish Orphan Biovitrum
Cerner Enviza

Active, not recruiting

An International Study to Evaluate the Real-world Effectiveness and Usage of Alprolix in Patients With Haemophilia B (B-MORE)

Hemophilia B

Czechia, Greece, Ireland, Italy, Norway, Saudi Arabia, Spain, Sweden, United Kingdom
Medstar Health Research Institute

Completed

Feasibility of Transcatheter Aortic Valve Replacement in Low-Risk Patients With Symptomatic, Severe Aortic Stenosis

Aortic Stenosis

United States
Abbott Medical Devices

Active, not recruiting

The CONFIDENCE Registry

Severe Aortic Stenosis | Symptomatic Degenerative Aortic Stenosis

Spain, Italy, United Kingdom, Germany, Switzerland, Czechia, Australia, Belgium, Poland
US Department of Veterans Affairs

Completed

Integrating Clinical Practice Guidelines for Smoking Cessation Into Mental Health Care for Veterans With Posttraumatic Stress Disorder

Substance-Related Disorders | Stress Disorders, Post-Traumatic | Tobacco Use Disorder | Mental Health

United States
Eli Lilly and Company

Active, not recruiting

A Study of LY3372993 in Participants With Alzheimer's Disease (AD) and Healthy Participants

Healthy | Alzheimer Disease

United States, Japan
European Society for Blood and Marrow Transplantation
Jazz Pharmaceuticals; Deutsche Krebshilfe e.V., Bonn (Germany)

Completed

Pediatric Trial Investigating the Incidence & Outcome of Veno-Occlusive Disease With the Prophylactic Use of Defibrotide (VOD-DF)

Hepatic Veno-Occlusive Disease

Sweden, United Kingdom, Italy, Switzerland, Germany, Austria, France, Ireland, Israel, Netherlands
Abbott Medical Devices

Completed

Amplatzer™Amulet™ Post-Market Study (Amulet™PMS) (Amulet™PMS)

Stroke | Atrial Fibrillation | Thromboembolism

Denmark, Finland, Poland, Italy, Spain, United Kingdom, Germany, Israel, Ireland, Norway, Australia, Belgium, Chile, France, Netherlands, Sweden
Novartis

Completed

Ph 1b Study to Evaluate GSK2110183 in Combination With Bortezomib and Dexamethasone in Subjects With Multiple Myeloma (PKB115125)

Multiple Myeloma

Canada, United States, Australia, Taiwan, Ireland
Alexion

Recruiting

Lysosomal Acid Lipase (LAL) Deficiency Registry (ALX-LALD-501)

Wolman Disease | Cholesterol Ester Storage Disease | Lysosomal Acid Lipase Deficiency | Acid Cholesteryl Ester Hydrolase Deficiency, Type 2 | Acid Lipase Deficiency | LIPA Deficiency | LAL-Deficiency

France, Belgium, United States, Spain, Germany, Greece, Israel, Italy, Slovenia, United Kingdom, Brazil, Canada, Denmark, Australia, Croatia, Czechia, Ireland, Mexico, Netherlands, Poland, Portugal, Saudi Arabia
University of California, Los Angeles
Mayo Clinic; IRCCS San Raffaele; National Taiwan University Hospital; Washington... and other collaborators

Completed

Stroke Inpatient Rehabilitation Reinforcement of ACTivity (SIRRACT)

Stroke

United States, Taiwan, Egypt, Turkey, Italy, Japan, India, Ireland, Korea, Republic of, New Zealand, Nigeria, Spain
Vertex Pharmaceuticals Incorporated

Completed

A Study of VX-121 Combination Therapy in Participants With Cystic Fibrosis (CF) Who Are Homozygous for F508del, Heterozygous for F508del and a Gating (F/G) or Residual Function (F/RF) Mutation, or Have At Least 1 Other Triple Combination Responsive (TCR) CFTR Mutation and No F508del Mutation

Cystic Fibrosis

United States, United Kingdom, Belgium, Netherlands, France, Denmark, Israel, New Zealand, Australia, Ireland, Sweden, Canada, Germany, Poland, Switzerland, Italy, Austria, Hungary, Greece, Norway
VA Office of Research and Development

Completed

Tadalafil for Pulmonary Hypertension Due to Chronic Lung Disease (TADA-PHILD)

Pulmonary Hypertension | Chronic Obstructive Pulmonary Disease (COPD)

United States
University of Pennsylvania
National Heart, Lung, and Blood Institute (NHLBI); Cephalon; Respironics Sleep...

Completed

Continuous Positive Airway Pressure to Improve Milder Obstructive Sleep Apnea (CATNAP)

Sleep Apnea Syndromes | Lung Diseases | Hypertension

United States, Canada
Medtronic Vascular

Completed

SPYRAL PIVOTAL - SPYRAL HTN-OFF MED Study

Cardiovascular Diseases | Vascular Diseases | Hypertension

United States, Canada, Germany, Australia, United Kingdom, Ireland, Japan, Austria, Greece
Alliance Foundation Trials, LLC.
Pharmacyclics LLC.

Active, not recruiting

Study of Ibrutinib in Combination With Revlimid/Dexamethasone in Relapsed/Refractory Multiple Myeloma

Multiple Myeloma | Refractory Multiple Myeloma | Multiple Myeloma in Relapse

United States
Vertex Pharmaceuticals Incorporated

Active, not recruiting

A Study Evaluating the Long-term Safety and Efficacy of VX-121 Combination Therapy

Cystic Fibrosis

United States, Spain, United Kingdom, Belgium, Netherlands, Denmark, Israel, New Zealand, France, Australia, Ireland, Germany, Sweden, Canada, Czechia, Switzerland, Portugal, Italy, Austria, Hungary, Norway, Poland, Greece
Vertex Pharmaceuticals Incorporated

Completed

A Study to Evaluate the Safety and Efficacy of Long Term Treatment With VX-661 in Combination With Ivacaftor in Participants With Cystic Fibrosis Who Have an F508del-CFTR Mutation

Cystic Fibrosis

United States, Australia, Canada, France, United Kingdom, Germany, Spain, Switzerland, Belgium, Israel, Netherlands, Denmark, Italy, Austria, Ireland, Sweden
Kiniksa Pharmaceuticals (UK), Ltd.

Completed

A Pilot Study of KPL-914 in Recurrent Pericarditis

Recurrent Pericarditis

United States
Vertex Pharmaceuticals Incorporated

Completed

A Study of Lumacaftor in Combination With Ivacaftor in Cystic Fibrosis Subjects Aged 12 Years and Older Who Are Homozygous for the F508del-CFTR Mutation (TRAFFIC)

Cystic Fibrosis, Homozygous for the F508del CFTR Mutation

United States, Germany, Canada, Netherlands, Czech Republic, Italy, Ireland, Sweden, United Kingdom, Australia, France
Wake Forest University Health Sciences

Terminated

Clot Dissolving Treatment for Blood Clots in the Lungs

Pulmonary Embolism

United States
Medtronic Cardiac Rhythm and Heart Failure
Medtronic

Completed

PREPARE - Primary Prevention Parameters Evaluation

Syncope | Tachycardia, Ventricular | Implantable Cardioverter Defibrillator (ICD) | Fibrillation, Ventricular

United States, Puerto Rico
Boston Scientific Corporation
EKOS Corporation

Withdrawn

Registry Study to Evaluate the Performance and Safety of Roxwood Medical Catheters in Arteries of Participants With a Stenotic Lesion or Chronic Total Occlusion (CTO)

Coronary Artery Disease | Atherosclerosis | Peripheral Artery Disease | Chronic Total Occlusion

United States
Novartis Pharmaceuticals

Completed

randOmized stUdy Using acceleromeTry to Compare Sacubitril/valsarTan and Enalapril in Patients With Heart Failure (OUTSTEP-HF)

Chronic Heart Failure With Reduced Ejection Fraction

Belgium, Estonia, Denmark, Greece, United Kingdom, Germany, Latvia, Lithuania, Spain, Netherlands, Bulgaria, Finland, Poland, Czechia, Iceland, Sweden, France, Ireland, Norway
Bioverativ Therapeutics Inc.
Swedish Orphan Biovitrum

Completed

Study of Recombinant Coagulation Factor IX Fc Fusion Protein, BIIB029, in Previously Treated Pediatric Participants With Hemophilia B (Kids B-LONG)

Hemophilia B

United States, United Kingdom, South Africa, Netherlands, Ireland, Australia
Nordic Myeloma Study Group
Janssen-Cilag Ltd.

Completed

Efficacy of Bortezomib Consolidation After High-dose Melphalan With Stem Cell Support in Myeloma Patients

Multiple Myeloma

Norway, Sweden, Denmark, Finland, Iceland

Clinical Trials on Infants Health in Ireland

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