Clinical Trials on Intact Skin in Italy

Total 2990 results

Pfizer

Completed

Study of CP-690,550 Versus Placebo In Rheumatoid Arthritis Patients On Background Methotrexate With Inadequate Response To Tumor Necrosis Factor (TNF) Inhibitors

Arthritis, Rheumatoid

Australia, United States, Austria, Germany, Ireland, Brazil, Spain, Taiwan, Belgium, Canada, France, Italy, Korea, Republic of, Puerto Rico
Boston Scientific Corporation

Recruiting

Registry of Deep Brain Stimulation With the VERCISE™ System: Vercise DBS Registry

Parkinson's Disease

United States, Korea, Republic of, Italy, Poland, Spain, France, Germany, Israel, United Kingdom, Belgium, Canada, Argentina, Austria, Hungary
CSL Behring

Completed

Phase IIB Rheumatoid Arthritis Dose Ranging Study for BMS-945429 in Subjects Who Are Not Responding to Methotrexate

Rheumatoid Arthritis

Italy, Japan, Taiwan, United States, Spain, Argentina, Belgium, Germany, Korea, Republic of, Czechia, Russian Federation, France, Mexico, Poland, South Africa, Hungary, Brazil, Canada, Netherlands
Novartis Pharmaceuticals

Withdrawn

Efficacy, Safety and Tolerability of Topically Applied LDE225 Cream (Hedgehog Pathway Inhibitor) in Adult Patients With Nevoid Basal Cell Carcinoma Syndrome (NBCCS)

Basal Cell Carcinoma

Greece, Switzerland, Germany, United Kingdom, Belgium, Canada, Czechia, Finland, Italy, Spain
Solvay Pharmaceuticals

Completed

An Open Label SLV308 Safety Extension to Study S308.3.003 in Early PD Patients

Early Stage Parkinson's Disease

United States, Australia, Czech Republic, Estonia, Germany, India, Italy, Lithuania, Malaysia, Netherlands, Poland, Portugal, South Africa, Taiwan, Thailand
GlaxoSmithKline

Completed

A Comparison of Ropinirole Immediate Release With Ropinirole Prolonged Release in Patients With Advanced Parkinson's

Parkinson Disease

Spain, France, Bulgaria, United Kingdom, Germany, Hungary, Russian Federation, South Africa, Italy, Canada, Czechia, Poland, Romania, Ukraine
Telios Pharma, Inc.

Recruiting

Study of TL-895 in Subjects With Myelofibrosis or Indolent Systemic Mastocytosis

Myelofibrosis | Indolent Systemic Mastocytosis

United States, Spain, Belgium, Australia, Taiwan, Germany, Poland, Korea, Republic of, Hungary, Brazil, Bulgaria, France, Italy
Bayer

Terminated

Assess Safety and Efficacy of Vilaprisan in Subjects With Uterine Fibroids (ASTEROID 5)

Uterine Fibroids

Spain, Korea, Republic of, Denmark, Taiwan, Hungary, Lithuania, Austria, Portugal, Germany, Australia, Canada, Sweden, Bulgaria, Czechia, Finland, Norway, Poland, United Kingdom, Belgium, Italy, Slovakia, Netherlands, Ireland
AstraZeneca

Recruiting

PASS of Paediatric Patients Initiating Selumetinib

Neurofibromatosis Type 1

Spain, United Kingdom, Israel, France, Italy, Portugal, Switzerland, Germany, Austria
Deciphera Pharmaceuticals LLC

Active, not recruiting

Study of Vimseltinib for Tenosynovial Giant Cell Tumor (MOTION)

Tenosynovial Giant Cell Tumor | Giant Cell Tumor of Tendon Sheath | Pigmented Villonodular Synovitis | Tenosynovial Giant Cell Tumor, Diffuse | Tenosynovial Giant Cell Tumor, Localized

Norway, United States, France, Spain, Hong Kong, Netherlands, Italy, Germany, Australia, United Kingdom, Canada, Poland, Switzerland
Takeda
Shire; Takeda Development Center Americas, Inc.

Recruiting

A Study of TAK-755 in Participants With Congenital Thrombotic Thrombocytopenic Purpura

Thrombotic Thrombocytopenic Purpura (TTP)

China, United States, France, Japan, Poland, Germany, Austria, Spain, Italy, Switzerland, United Kingdom
AbbVie

Recruiting

Program to Assess Adverse Events and Change in Disease Activity of Oral Upadacitinib in Adult Participants With Moderate to Severe Systemic Lupus Erythematosus (SELECT-SLE)

Systemic Lupus Erythematosus

United States, Japan, Puerto Rico, Switzerland, Israel, Korea, Republic of, Hungary, New Zealand, Bulgaria, Latvia, Taiwan, Slovakia, Croatia, South Africa, Australia, Poland, Portugal, Spain, Estonia, France, Lithuania, Brazil, Ger... and more
Hoffmann-La Roche

Completed

A Study to Assess the Safety and Efficacy of Tocilizumab in Patients With Active Rheumatoid Arthritis

Rheumatoid Arthritis

France, Italy, Spain, United States, Australia, Canada, Mexico, South Africa, Portugal, Slovenia, Serbia, Israel, Lithuania, Argentina, China, Denmark, Norway, Peru
Eli Lilly and Company

Recruiting

A Study of Baricitinib in Participants From 1 Year to Less Than 18 Years Old With Juvenile Idiopathic Arthritis (JUVE-X)

Juvenile Idiopathic Arthritis

Belgium, Spain, Australia, India, Japan, Italy, Czechia, Austria, France, United Kingdom, Mexico, Israel, Brazil, China, Denmark, Germany, Poland, Russian Federation, Argentina, Turkey
Agenus Inc.

Completed

Study of Heat Shock Protein-Peptide Complex (HSPPC-96) Versus IL-2/DTIC for Stage IV Melanoma

Malignant Melanoma

United States, Australia, Poland, Ukraine, United Kingdom, Russian Federation, Hungary, Italy, Sweden
Eli Lilly and Company

Completed

A Study of Baricitinib in Participants From 2 Years to Less Than 18 Years Old With Juvenile Idiopathic Arthritis (JUVE-BASIS)

Juvenile Idiopathic Arthritis

Spain, India, Israel, Japan, Australia, Belgium, Turkey, Mexico, Italy, Germany, Czechia, United Kingdom, China, Russian Federation, Poland, Brazil, France, Austria, Argentina, Denmark
Cerevel Therapeutics, LLC

Active, not recruiting

Fixed-Dose Trial in Early Parkinson's Disease (PD) (TEMPO-1)

Parkinson Disease

Spain, United States, Australia, Bulgaria, Canada, Czechia, France, Germany, Israel, Italy, Poland, Ukraine
Amgen

Completed

Study of Etanercept Monotherapy vs Methotrexate Monotherapy for Maintenance of Rheumatoid Arthritis Remission

Rheumatoid Arthritis

United States, Germany, Italy, Mexico, France, Canada, Hungary, Portugal, Spain, Greece, Bulgaria, Czechia, Poland, Argentina, South Africa
Amgen

Terminated

Efficacy and Safety of Efavaleukin Alfa in Subjects With Active Systemic Lupus Erythematosus

Active Systemic Lupus Erythematosus

Korea, Republic of, United States, Taiwan, Canada, Spain, Italy, Mexico, Japan, Turkey, Austria, Greece, Colombia, Switzerland, Poland, France, Bulgaria, Hong Kong, Russian Federation, Chile
Bial R&D Investments, S.A.

Recruiting

Efficacy, Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of BIA 28-6156 in GBA-PD (ACTIVATE)

Parkinson's Disease

United States, Spain, France, Italy, Netherlands, United Kingdom, Germany, Canada, Poland, Portugal, Sweden
Cerevel Therapeutics, LLC

Completed

Flexible-Dose, Adjunctive Therapy Trial in Adults With Parkinson's Disease With Motor Fluctuations (TEMPO-3)

Parkinson Disease

Germany, Spain, United States, Australia, Bulgaria, Czechia, France, Israel, Italy, Poland, Ukraine, Serbia
Intec Pharma Ltd.

Unknown

A Study of AP-CD/LD in Fluctuating Parkinson's Disease Patients Who Completed IN 11 004

Parkinson's Disease

United States, Israel, Italy, Spain, United Kingdom, Bulgaria, Germany, Poland, Slovakia, Ukraine
Bristol-Myers Squibb

Completed

Remission and Joint Damage Progression in Early Rheumatoid Arthritis

Rheumatoid Arthritis

Korea, Republic of, United States, Spain, Puerto Rico, Belgium, Australia, Canada, Mexico, France, Germany, Netherlands, Russian Federation, South Africa, United Kingdom, Brazil, Czech Republic, Italy, Poland
Baxalta now part of Shire
Takeda Development Center Americas, Inc.

Completed

A Study of BAX 930 in Children, Teenagers, and Adults Born With Thrombotic Thrombocytopenic Purpura (TTP)

Thrombotic Thrombocytopenic Purpura (TTP)

United States, Spain, Germany, Italy, Poland, Japan, Austria, United Kingdom, France
Amgen

Completed

Efficacy and Safety of AMG 570 in Subjects With Active Systemic Lupus Erythematosus (SLE)

Systemic Lupus Erythematosus (SLE)

United States, Korea, Republic of, Australia, Spain, Hungary, Bulgaria, Italy, Mexico, Germany, Japan, France, Greece, Czechia, Argentina, Portugal, Poland, Russian Federation, Hong Kong, Canada
University College, London
CHDI Foundation, Inc.

Recruiting

HDClarity: a Multi-site Cerebrospinal Fluid Collection Initiative to Facilitate Therapeutic Development for Huntington's Disease (HDClarity)

Huntington's Disease

United States, United Kingdom, France, Canada, Germany, Italy, Spain, New Zealand, Poland
Hoffmann-La Roche

Completed

An Observational Study of MabThera/Rituxan (Rituximab) and Alternative TNF-Inhibitors in Patients With Rheumatoid Arthritis and an Inadequate Response to a Single Previous TNF-Inhibitor

Rheumatoid Arthritis

France, Germany, Colombia, Canada, Spain, United Kingdom, Greece, Italy, Mexico, Portugal, Norway, Monaco
AbbVie

Completed

A Phase 4 Trial Assessing the ImPact of Residual Inflammation Detected Via Imaging TEchniques, Drug Levels and Patient Characteristics on the Outcome of Dose TaperIng of Adalimumab in Clinical Remission Rheumatoid ArThritis (RA) Subjects (PREDICTRA)

Rheumatoid Arthritis | Musculoskeletal and Connective Tissue Diseases

United States, Australia, Austria, Canada, France, Germany, Greece, Hungary, Ireland, Italy, Netherlands, Spain, Sweden, United Kingdom
SpringWorks Therapeutics, Inc.

Active, not recruiting

Nirogacestat for Adults With Desmoid Tumor/Aggressive Fibromatosis (DT/AF) (DeFi)

Desmoid Tumor | Aggressive Fibromatosis

United States, Belgium, Germany, Canada, Italy, Netherlands, United Kingdom
Eli Lilly and Company
Incyte Corporation

Terminated

A Study of Baricitinib in Participants With Systemic Lupus Erythematosus (SLE) (SLE-BRAVE-X)

Systemic Lupus Erythematosus

United States, China, France, Czechia, Taiwan, Hungary, Belgium, Australia, Korea, Republic of, Serbia, Mexico, Poland, Italy, United Kingdom, Germany, Spain, Japan, South Africa, Austria, Russian Federation, Israel, India, Argentina, Croati... and more
Hoffmann-La Roche

Completed

A Study to Assess the Effect of Tocilizumab + Methotrexate on Signs and Symptoms in Patients With Moderate to Severe Active Rheumatoid Arthritis Currently on Methotrexate Therapy

Rheumatoid Arthritis

France, Germany, Italy, Australia, United States, Canada, Mexico, United Kingdom, Sweden, Belgium, Switzerland, Netherlands, Puerto Rico, Iceland
Bellus Health Inc
FDA Office of Orphan Products Development

Completed

Study of the Safety and Efficacy of NC-503 in Secondary (AA) Amyloidosis

Gastrointestinal Diseases | Kidney Diseases | Rheumatoid Arthritis | Nephrotic Syndrome | Secondary (AA) Amyloidosis | Familial Mediterranean Syndrome

United States, Israel, Finland, France, Italy, Lithuania, Netherlands, Poland, Russian Federation, Spain, Turkey, United Kingdom
Eli Lilly and Company

Completed

A Moderate to Severe Rheumatoid Arthritis Study (RA-BEACON)

Rheumatoid Arthritis

United States, Israel, Turkey, Spain, Puerto Rico, Germany, Italy, France, Japan, Mexico, United Kingdom, Austria, Denmark, Poland, Australia, Greece, Switzerland, Argentina, Korea, Republic of, Belgium, Canada, Netherlands
Hoffmann-La Roche
Biogen

Completed

A Study to Evaluate the Safety and Efficacy of MabThera (Rituximab) in Combination With Methotrexate (MTX) in Participants With Active Rheumatoid Arthritis Who Failed on Anti-Tumor Necrosis Factor Alpha Therapy

Rheumatoid Arthritis

Belgium, France, Germany, Norway, United Kingdom, United States, Ireland, Canada, Israel, Netherlands, Italy
GlaxoSmithKline

Completed

An Open-label Continuation Study Evaluating the Long-term Safety of Extended Release Ropinirole XL (Formerly CR) in Parkinson''s Disease

Parkinson's Disease | Parkinson Disease

United States, Spain, Poland, France, Belgium, Hungary, United Kingdom, Italy, Czech Republic
UCB Pharma SA

Completed

A Multi-center, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Certolizumab Pegol in Combination With Methotrexate in the Treatment of Disease Modifying Antirheumatic Drugs (DMARD)-naïve Adults With Early Active Rheumatoid Arthritis (C-early)

Rheumatoid Arthritis

Germany, United States, Argentina, Australia, Austria, Belgium, Canada, Colombia, Czechia, France, Hungary, Ireland, Italy, Mexico, Monaco, Netherlands, Poland, Romania, Spain, Sweden, Switzerland, United Kingdom
Novartis Pharmaceuticals

Completed

Efficacy at 24 Weeks and Safety, Tolerability and Long Term Efficacy up to 2 Years of Secukinumab (AIN457) in Patients With Active Rheumatoid Arthritis and an Inadequate Response to Anti-TNFα Agents (REASSURE)

Rheumatoid Arthritis

Colombia, United States, Belgium, Turkey, Thailand, Argentina, Italy, Guatemala, India, Japan, Panama, Hungary, United Kingdom, Mexico, Puerto Rico, Canada
Eli Lilly and Company

Completed

A Study in Participants With Moderate to Severe Rheumatoid Arthritis (RA-BEGIN)

Rheumatoid Arthritis

United States, Argentina, India, Korea, Republic of, Puerto Rico, Italy, Belgium, Canada, Japan, Mexico, Russian Federation, United Kingdom, Germany, Portugal, Greece, South Africa, Brazil, Austria, Sweden
UCB Pharma SA
Parexel

Completed

Study to Assess the Short- and Long-term Efficacy of Certolizumab Pegol Plus Methotrexate Compared to Adalimumab Plus Methotrexate in Subjects With Moderate to Severe Rheumatoid Arthritis (RA) Inadequately Responding to Methotrexate

Rheumatoid Arthritis

Romania, United States, Australia, Austria, Bulgaria, Canada, Czechia, France, Germany, Greece, Hungary, Ireland, Italy, Mexico, Monaco, Poland, Portugal, Spain, Switzerland, United Kingdom
UCB Biopharma SRL

Enrolling by invitation

An Extension Study to Evaluate the Long-Term Efficacy, Safety and Tolerability of Minzasolmin (UCB0599) in Study Participants With Parkinson's Disease

Parkinson's Disease

United States, Poland, Netherlands, France, Germany, Canada, Italy, Spain, United Kingdom
Eisai Limited

Completed

The Efficacy, Safety and Tolerability of E2007 in Levodopa Treated Parkinson's Disease Patients With Motor Fluctuations

Parkinson's Disease

Poland, France, Spain, Germany, Hungary, Italy, Estonia, South Africa, Belgium, United Kingdom, Portugal, Austria, Czech Republic, Israel, Lithuania, Serbia, Sweden
Eli Lilly and Company

Completed

A Study of Abemaciclib (LY2835219) in Participants With Breast Cancer, Non-small Cell Lung Cancer, or Melanoma That Has Spread to the Brain

Melanoma | Breast Cancer | Non-small Cell Lung Cancer | Brain Metastases

Spain, United States, Australia, Italy, France, Belgium, Canada, Austria, Israel
Novartis Pharmaceuticals
International Maternal Pediatric Adolescent AIDS Clinical Trials Group; Southwest...

Terminated

Single-dose Study to Assess Efficacy of Canakinumab (ACZ885) in Patients With Active Juvenile Idiopathic Arthritis (SJIA) (β-SPECIFIC 1)

Systemic Juvenile Idiopathic Arthritis

United States, Argentina, Canada, Switzerland, Germany, United Kingdom, Israel, South Africa, Belgium, Greece, Italy, Spain, France, Brazil, Turkey, Hungary, Poland, Norway, Sweden, Netherlands, Peru, Denmark
Alterity Therapeutics

Recruiting

Study of ATH434 in Participants With Multiple System Atrophy

Multiple System Atrophy

United States, Australia, New Zealand, United Kingdom, Italy, France, Austria
Eli Lilly and Company

Completed

A Study in Moderate to Severe Rheumatoid Arthritis Participants (RA-BUILD)

Rheumatoid Arthritis

United States, India, Hungary, Puerto Rico, Romania, Poland, Belgium, Canada, Russian Federation, Spain, Japan, Argentina, Croatia, Australia, Taiwan, Italy, Czechia, Mexico, Korea, Republic of, United Kingdom, Slovakia, Germany, Po...
AstraZeneca

Completed

Evaluation of Effectiveness of Two Dosing Regimens of Fostamatinib Compared to Placebo in Patients With Rheumatoid Arthritis (RA) Who Are Taking Methotrexate and Have Had Inadequate Response to Single TNF-alpha Antagonist (OSKIRA - 3)

Rheumatoid Arthritis

United States, Czech Republic, Mexico, South Africa, Spain, United Kingdom, Germany, Argentina, Belgium, Canada, Hungary, Israel, Portugal, France, Brazil, Italy
Bristol-Myers Squibb

Completed

Study of Abatacept (BMS-188667) in Subjects With Active Rheumatoid Arthritis on Background Non-biologic DMARDS (Disease Modifying Antirheumatic Drugs) Who Have an Inadequate Response to Anti-TNF Therapy

Rheumatoid Arthritis

Belgium, Spain, United States, Germany, Italy, Mexico, United Kingdom, France, Czech Republic, Ireland
Quince Therapeutics S.p.A.

Completed

Intra-Erythrocyte Dexamethasone Sodium Phosphate in Ataxia Telangiectasia Patients (ATTeST)

Genetic Syndrome | Nervous System Disease

India, United States, Australia, Germany, Italy, Norway, Poland, Spain, Tunisia, United Kingdom, Israel, Belgium
ACADIA Pharmaceuticals Inc.

Completed

A Study of Safety and Efficacy of Pimavanserin (ACP-103) in Patients With Parkinson's Disease Psychosis

Parkinson's Disease Psychosis

Spain, United States, Belgium, Austria, Serbia, Poland, Portugal, Italy, Sweden
AbbVie

Active, not recruiting

Extension Study To Evaluate Safety And Tolerability Of 24-Hour Daily Exposure Of Continuous Subcutaneous Infusion of ABBV-951 In Adult Participants With Parkinson's Disease

Parkinson's Disease (PD)

United States, Australia, Belgium, Canada, Denmark, Germany, Italy, Japan, Netherlands, Russian Federation, Spain, United Kingdom, Sweden

Clinical Trials on Intact Skin in Italy

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