Clinical Trials on Intrahepatic Cholestases

Total 684 results

Beaujon Hospital

Unknown

Reconstruction of the Bile Duct With the Round Ligament

Bile Duct Obstruction, Extrahepatic

France
Albireo

Completed

An Open Label, Single-dose, Single Period ADME Study of A4250 in Healthy Subjects

Primary Biliary Cirrhosis | Alagille Syndrome | Progressive Familial Intrahepatic Cholestasis | Orphan Cholestatic Liver Diseases

United Kingdom
Albireo

Completed

A Safety and Pharmakokinetic Study of A4250 Alone or in Combination With A3384

Primary Biliary Cirrhosis | Alagille Syndrome | Progressive Familial Intrahepatic Cholestasis | Orphan Cholestatic Liver Diseases
Alexandra Hospital, Athens, Greece

Recruiting

Genetic Polymorphisms of ABCB11 and ABCB4 in Women With Intrahepatic Cholestasis of Pregnancy (ICP) and in Their First Degree Relatives

Cholestasis of Pregnancy

Greece
Santi Mangiafico

Not yet recruiting

Partially Covered Metal Stents Efficacy in Biliary Drainage of Malignant Extra-hepatic Biliary Obstruction (METARSI)

Biliary Obstruction
Fondazione Policlinico Universitario Agostino Gemelli...

Recruiting

Diet in Twin Pregnancy: the Wellness of Mother and Babies. (FIT)

Diet, Healthy | Gestational Diabetes | Intrahepatic Cholestasis of Pregnancy | Food Habits | Twin Pregnancy, Antepartum Condition or Complication | Gestational Hypertension

Italy
Children's Hospital of Fudan University

Withdrawn

BSEP Function Rescue During Childhood Inhereditary Cholestatic Diseases

Cholestasis, Intrahepatic | Hereditary Diseases
Intercept Pharmaceuticals

Terminated

Study of INT 747 in Combination With URSO in Patients With Primay Biliary Cirrhosis (PBC)

Liver Cirrhosis, Biliary

United States, Spain, Canada, United Kingdom, France, Germany, Austria, Netherlands
National Institute of Diabetes and Digestive and...

Completed

Ursodiol-Methotrexate for Primary Biliary Cirrhosis

Liver Cirrhosis, Biliary

United States
National Center for Research Resources (NCRR)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); University...

Completed

Phase III Randomized Study of Ursodiol With Vs Without Methotrexate for Primary Biliary Cirrhosis

Liver Cirrhosis, Biliary
Samsung Medical Center

Unknown

Study of GEMOX(Gemcitabine/Oxaliplatin) Versus XELOX(Xeloda/Oxaliplatin) in Advanced Biliary Tract Carcinoma

Biliary Tract (Intrahepatic, Extrahepatic Cholangiocarcinoma, Gall Bladder) Cancer

Korea, Republic of
Assistance Publique - Hôpitaux de Paris
University of Paris 5 - Rene Descartes

Completed

Trial of Psychoeducational and Hypnosis Interventions on the Fatigue Associated With PBC in Women (CBP-HOPE)

Liver Cirrhosis, Biliary

France
Sun Yat-sen University

Completed

Gut Microbes and Metabolic Group in Different PBC Patients for UDCA Response

Primary Biliary Cirrhosis

China
Xijing Hospital of Digestive Diseases

Unknown

Fuzhenghuayu for Patients With PBC Who Had An Inadequate Response to Ursodeoxycholic Acid

Primary Biliary Cirrhosis

China
University of Aarhus

Completed

Effect of Obeticholic Acid on Transport of Bile Acids in PBC Examined by 11C-cholyl-sarcosine PET/CT

Primary Biliary Cirrhosis

Denmark
University of California, Davis

Completed

Identification of Inflammatory and Fibrotic Biomarkers in PBC and NAFLD Patients

Primary Biliary Cirrhosis

United States
Zydus Therapeutics Inc.

Not yet recruiting

Open-Label Extension Study of Saroglitazar Magnesium in Participants With Primary Biliary Cholangitis

Primary Biliary Cholangitis

United States, Turkey, Argentina
Hospital Mutua de Terrassa

Recruiting

Detection Program for Patients With Primary Biliary Cholangitis Lost in the System (RESCAT)

Primary Biliary Cholangitis

Spain
Henning Grønbæk
Aarhus University Hospital; Region Hovedstadens Apotek; Hospitalsapoteket Region... and other collaborators

Recruiting

PBC Induced Fatigue Treated With Thiamine (PIFT)

Primary Biliary Cirrhosis

Denmark
Peking Union Medical College Hospital

Recruiting

Clinical Research of UCDA Reducing Medication Regimen in Stable PBC (UCDA PBC)

Primary Biliary Cholangitis

China
Xijing Hospital of Digestive Diseases

Recruiting

Fenofibrate in Combination With Ursodeoxycholic Acid in Primary Biliary Cirrhosis

Primary Biliary Cirrhosis

China
University of Alberta
Merck Sharp & Dohme LLC

Completed

Combination Antiretroviral Therapy (cART) for PBC

Primary Biliary Cholangitis

Canada
Assistance Publique - Hôpitaux de Paris

Completed

Phase 3 Study of Bezafibrate in Combination With Ursodeoxycholic Acid in Primary Biliary Cirrhosis (BEZURSO)

PBC

France
Intercept Pharmaceuticals
Syneos Health; Global PBC Study Group; Target RWE; UK PBC Group

Completed

Real-World Data Study to Evaluate the Effectiveness of OCA on Hepatic Outcomes in PBC Patients (HEROES PBC)

Primary Biliary Cholangitis

United States
CymaBay Therapeutics, Inc.

Completed

ENHANCE: Seladelpar in Subjects With Primary Biliary Cholangitis (PBC) and an Inadequate Response to or an Intolerance to Ursodeoxycholic Acid (UDCA)

Primary Biliary Cholangitis

United States, Spain, United Kingdom, Israel, France, Korea, Republic of, Australia, Italy, Hungary, Germany, Romania, Belgium, Canada, Greece, New Zealand, Austria, Serbia, Russian Federation, Argentina, Mexico, Netherlands, Chile, Polan...
Intercept Pharmaceuticals

Completed

Study of INT-747 as Monotherapy in Participants With Primary Biliary Cirrhosis (PBC)

Liver Cirrhosis, Biliary

United States, France, Germany, Spain, United Kingdom, Canada, Austria
Enanta Pharmaceuticals, Inc
Pharmaceutical Research Associates; Triangle Biostatistics

Completed

A Study to Assess the Safety, Tolerability, Pharmacokinetics and Efficacy of EDP-305 in Subjects With Primary Biliary Cholangitis

Primary Biliary Cholangitis

United States, Spain, Canada, Australia, United Kingdom, Germany, Netherlands, Belgium, Austria, France
Eli Lilly and Company

Terminated

A Study of Baricitinib (LY3009104) in Participants With Primary Biliary Cholangitis Who do Not Respond or Cannot Take UDCA

Primary Biliary Cholangitis

United States, Puerto Rico
Dr. Falk Pharma GmbH

Completed

Ursofalk Tablets (500 mg) Versus Ursofalk Capsules (250 mg) in the Treatment of Primary Biliary Cirrhosis

Primary Biliary Cirrhosis

Germany
West China Hospital

Unknown

A Trial of 18-22mg/kg/d Ursodeoxycholic in Refractory Primary Biliary Cholangitis

Primary Biliary Cholangitis

China
Instituto Nacional de Ciencias Medicas y Nutricion...

Unknown

Use of Bezafibrate in Patients With Primary Biliary Cirrhosis to Archive Complete Biochemical Response in Non-responders

Primary Biliary Cirrhosis

Mexico
University of Florida
Shionogi Inc.; The PBCers Organization

Completed

Use of Fenofibrate for Primary Biliary Cirrhosis

Primary Biliary Cirrhosis

United States
Benedetta Terziroli, MD
Intercept Pharmaceuticals; Vifor Pharma; Fondazione Epatocentro Ticino

Completed

The Health Burden of Primary Biliary Cirrhosis (PBC) in Switzerland

Primary Biliary Cirrhosis

Switzerland
University of Miami
Mayo Clinic

Withdrawn

Fenofibrate in Combination With Ursodeoxycholic Acid (UDCA) in Primary Biliary Cirrhosis

Primary Biliary Cirrhosis

United States
The Cleveland Clinic

Completed

Pentoxifylline for Primary Biliary Cirrhosis

Primary Biliary Cirrhosis

United States
Beijing 302 Hospital

Withdrawn

Efficacy and Safety of Fenofibrate Combined With UDCA in PBC Patients With an Incomplete Biochemical Response to UDCA

Primary Biliary Cirrhosis

China
Cairo University

Completed

Physical Therapy for Liver Cirrhosis

Liver Cirrhosis, Biliary

Egypt
Mei Han

Not yet recruiting

Clinical Study on the Treatment of Elevated Total Bilirubin in Primary Biliary Cholangitis With Baobao Dan Capsule

Primary Biliary Cholangitis
Xijing Hospital of Digestive Diseases

Recruiting

Fenofibrate in Patients With Primary Biliary Cholangitis (PBC)

Primary Biliary Cholangitis

China
Kowa Research Institute, Inc.

Recruiting

Study to Evaluate the Efficacy and Safety of K-808 (Pemafibrate) in Participants With Primary Biliary Cholangitis (PBC) With Inadequate Response to Ursodeoxycholic Acid (UDCA) and/or Obeticholic Acid (OCA) Treatment.

Primary Biliary Cholangitis

United States, Japan
Han Ying

Recruiting

Fenofibrate in Combination With Ursodeoxycholic Acid in Primary Biliary Cholangitis

Primary Biliary Cholangitis

China
CymaBay Therapeutics, Inc.

Recruiting

IDEAL: Intended to Determine the Effects of Seladelpar on Normalization of Alkaline Phosphatase Levels in Subjects With Primary Biliary Cholangitis (PBC) and an Incomplete Response or Intolerance to Ursodeoxycholic Acid (UDCA) (IDEAL)

Primary Biliary Cholangitis

United States
CymaBay Therapeutics, Inc.

Recruiting

Seladelpar in Subjects With Primary Biliary Cholangitis (PBC) and Compensated Cirrhosis (AFFIRM)

Primary Biliary Cholangitis

United States, Korea, Republic of, Turkey
Xijing Hospital of Digestive Diseases

Recruiting

Fenofibrate for Compensated Cirrhosis Patients With Primary Biliary Cholangitis

Primary Biliary Cholangitis

China
Nanjing Chia-tai Tianqing Pharmaceutical

Recruiting

Efficacy and Safety of Obeticholic Acid in the Treatment of Primary Biliary Cholangitis

Primary Biliary Cholangitis

China
Zydus Therapeutics Inc.

Active, not recruiting

Saroglitazar Magnesium for Treatment of Primary Biliary Cholangitis (EPICS-III)

Primary Biliary Cholangitis

United States, Argentina, Iceland, Turkey
Intercept Pharmaceuticals

Active, not recruiting

Study of OCA in Combination With BZF Evaluating Efficacy, Safety and Tolerability in Participants With PBC

Primary Biliary Cholangitis

United States
Gannex Pharma Co., Ltd.

Completed

Study to Evaluate the Safety and Efficacy of ASC42 Tablets in Subjects With Primary Biliary Cholangitis

Primary Biliary Cholangitis

China
Mayo Clinic

Active, not recruiting

Genetic Epidemiology of Primary Biliary Cirrhosis (PBC)

Primary Biliary Cirrhosis

United States
Cascade Pharmaceuticals, Inc

Completed

Study of [14C]CS0159 in China Healthy Subjects

Primary Biliary Cholangitis

China

Clinical Trials on Intrahepatic Cholestases

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