Clinical Trials on Intrinsic Sphincter Deficiency in South Africa

Total 917 results

QOL Medical, LLC

Recruiting

7-Day Trial of Sucraid for Alleviating CSID Symptoms in Subjects With Low, Moderate, and Normal Sucrase Levels

Congenital Sucrase-Isomaltase Deficiency | CSID | Sucrase Isomaltase Deficiency

United States
Watson Pharmaceuticals

Completed

2 Doses of Ferrlecit Versus Oral Iron to Treat Iron-deficiency Anemia in Peritoneal Dialysis Patients.

Iron Deficiency Anemia

United States, Canada, Mexico, Bulgaria, India, Russian Federation, Croatia, Poland
ViiV Healthcare

Active, not recruiting

Dolutegravir Study in HIV-1 Participants Completing IMPAACT Studies P1093 and P2019

HIV Infections

United States, Thailand, Brazil, South Africa, Zimbabwe, Botswana, Tanzania
National Institute of Allergy and Infectious Diseases...
HIV Prevention Trials Network

Completed

Preventing Sexual Transmission of HIV With Anti-HIV Drugs

HIV Infections

Brazil, Malawi, India, Botswana, Kenya, South Africa, Zimbabwe, United States, Thailand
AMAG Pharmaceuticals, Inc.

Completed

A Trial of Ferumoxytol for the Episodic Treatment of Iron Deficiency Anemia

Iron Deficiency Anemia

United States, Canada, Hungary, India, Latvia, Poland
Sheffield Teaching Hospitals NHS Foundation Trust
Sheffield Hallam University

Completed

Peripheral Vascular Function in Obstructive Sleep Apnoea

Obesity | Obstructive Sleep Apnoea

United Kingdom
Baxalta now part of Shire
Baxter Healthcare, Ltd. (New Zealand), Baxter Healthcare Pty. Ltd. (Australia)

Completed

Pharmacokinetic Study of ARALAST (Human Alpha1- PI)

Alpha 1-Antitrypsin Deficiency

Australia, New Zealand
Medical University of South Carolina
National Center for Research Resources (NCRR); Alpha-1 Foundation

Completed

The Use of High Resolution Chest Computed Tomography in Alpha-1 Antitrypsin Deficiency (QUANTUM-1)

Alpha-1 Antitrypsin Deficiency

United States
Fisher and Paykel Healthcare

Completed

Comparison Study of the ICON™ CPAP Series With and Without SensAwake™

Obstructive Sleep Apnea

United States
Baxter Healthcare Corporation

Terminated

Pediatric Study to Evaluate Risk of Developing Essential Fatty Acid Deficiency When Receiving Clinolipid or Standard-of-Care Lipid Emulsion

Essential Fatty Acid Deficiency (EFAD)

United States
Sheffield Teaching Hospitals NHS Foundation Trust
Sheffield Hallam University

Completed

Lifestyle Intervention in Obstructive Sleep Apnoea

Obesity | Obstructive Sleep Apnoea

United Kingdom
Alkermes, Inc.

Recruiting

A Study to Evaluate the Safety and Effectiveness of ALKS 2680 in Subjects With Narcolepsy Type 1 (ALKS 2680-201) (Vibrance-1)

Narcolepsy Type 1

United States
Verily Life Sciences LLC

Completed

Baseline Sleep Apnea Study #2

Obstructive Sleep Apnea of Adult

United States
Pharmacosmos A/S

Completed

Iron Isomaltoside/Ferric Derisomaltose vs Iron Sucrose for the Treatment of Iron Deficiency Anemia (IDA)

Iron Deficiency Anemia | Iron Deficiency Anaemia

United States
AMAG Pharmaceuticals, Inc.

Completed

A Trial Comparing Ferumoxytol With Placebo for the Treatment of Iron Deficiency Anemia

Iron Deficiency Anemia

United States, Canada, Hungary, India, Latvia, Poland
Sunovion

Completed

This is a Study to Determine the Effect of Multiple Doses of an Investigational Drug, Taken by Mouth, in People With Narcolepsy-cataplexy. Accepting Both Males and Females Ages of 18 Years to 55 Years. This Study Will be Conducted in the US and Will Require Approximately 13 Weeks Participation.

Narcolepsy

United States
Merck KGaA, Darmstadt, Germany

Completed

An Open-label Phase 4 Study to Explore Immunogenicity of the Liquid Formulation of Saizen® in Subjects With Adult Growth Hormone Deficiency (AGHD)

Adult Growth Hormone Deficiency

United Kingdom, Germany, Australia, Sweden
Sheffield Children's NHS Foundation Trust

Completed

Improved Discrimination Of Central And Obstructive Apnoeas In Infants

Central And Obstructive Apnoeas In Infants

United Kingdom
Grifols Therapeutics LLC

Completed

Comparison of Pharmacokinetic, Safety, Tolerability of Alpha-1 MP and Prolastin In Alpha1-antitrypsin Deficient Adults (ChAMP)

Alpha 1-Antitrypsin Deficiency

United States
Philips Electronics Nederland B.V. acting through...
Sanford Health

Terminated

Effective Conversion of Individuals at Risk

Atrial Fibrillation | Obstructive Sleep Apnea

United States
National Institute of Allergy and Infectious Diseases...

Completed

Evaluating the Safety and Pharmacokinetics of Raltegravir in Infants

HIV Infections

United States, South Africa, Brazil, Tanzania, Thailand
The Queen Elizabeth Hospital
Lyell McEwin Hospital

Unknown

The SAD Study - SLEEP, ANXIETY & DEPRESSION Study A Prospective Cohort Study (SAD)

COPD | Obstructive Sleep Apnoea | Patients With Anxiety and Depression, Who Have

Australia
Holdsworth House Medical Practice
Atomo Diagnostics

Completed

Performance and Usability Evaluation of the Atomo HIV Self-Test

HIV Infections

Australia
Kirby Institute
Hoffmann-La Roche

Completed

A 48-Week, Randomised, Study to Describe the Pharmacokinetic Profile and Durability of Atazanavir-Saquinavir-Ritonavir Once Daily and Describe the Pharmacokinetic Profile of Saquinavir-Ritonavir Using Saquinavir 500mg Formulation: the ASK-500 Study (ASK-500)

HIV Infections

Australia
University of South Carolina

Completed

Could Dietary Algae Affect Immunity and Viral Counts in People With HIV? (HIV)

HIV Infections

United States
Kirby Institute

Completed

Safety and Efficacy of Reduced Versus Standard Dose Efavirenz (EFV) Plus Two Nucleotides in Antiretroviral-naïve Adults. (ENCORE1)

HIV Infections

Australia
National Institute of Allergy and Infectious Diseases...

Completed

Evaluation of the Safety of and Immune Response to an HIV Vaccine in Healthy Adults

HIV Infections

Australia
PENTA Foundation
Institut National de la Santé Et de la Recherche Médicale, France; Program... and other collaborators

Active, not recruiting

A Randomised Trial of Dolutegravir (DTG)-Based Antiretroviral Therapy vs. Standard of Care (SOC) in Children With HIV Infection Starting First-line or Switching to Second-line ART

HIV Infection

United Kingdom, Spain, Portugal, South Africa, Thailand, Uganda, Germany, Zimbabwe
Janssen R&D Ireland

Completed

TMC125-TiDP2-C238: An Exploratory Pharmacokinetics, Safety and Anti-HIV Activity Study of Etravirine (ETR) When Given With Boosted Atazanavir (ATV/Rtv) at Two Different Doses and 1 Nucleoside Reverse Transcriptase Inhibitor (NRTI) in Treatment Experienced HIV Patients

HIV Infections | Acquired Immunodeficiency Syndrome

United States, France, Argentina, South Africa, Thailand
Grifols Therapeutics LLC

Active, not recruiting

Efficacy and Safety of Alpha1-Proteinase Inhibitor (Human), Modified Process (Alpha-1 MP) in Subjects With Pulmonary Emphysema Due to Alpha1 Antitrypsin Deficiency (AATD) (SPARTA)

Pulmonary Emphysema in Alpha-1 PI Deficiency

United States, Australia, Denmark, New Zealand, Estonia, Poland, Russian Federation, Sweden, Brazil, Canada, France, Finland
Takeda

Completed

Long-Term Efficacy of Ramelteon on Endocrine Function in Adult Subjects With Chronic Insomnia

Insomnia

United States
HIV Vaccine Trials Network
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

A Study of Patients Who Develop HIV Infection After Enrolling in HIV Vaccine Trials or HIV Vaccine Preparedness Trials

HIV Infections

United States, South Africa, Peru, Brazil
Merck Sharp & Dohme LLC

Completed

Safety and Immunogenicity of V114 in Children Infected With Human Immunodeficiency Virus (HIV) (V114-030/PNEU-WAY PED) (PNEU-WAY PED)

Pneumococcal Infections

South Africa, Thailand, Ukraine
Takeda

Enrolling by invitation

An Extension Study to Learn About the Long-Term Safety of Fazirsiran and if Fazirsiran Can Help People With Alpha-1 Antitrypsin Liver Disease

Alpha1-Antitrypsin Deficiency

United Kingdom, Germany, United States, Austria, Portugal
ViiV Healthcare
GlaxoSmithKline

Completed

Study Of An Investigational Regimen Including FDA Approved HIV Drugs In HIV-Infected Pediatric Subjects

HIV Infections | Infection, Human Immunodeficiency Virus

United States, Portugal, Russian Federation, Mexico, Argentina, South Africa, Puerto Rico
Pharming Technologies B.V.

Completed

Efficacy, Safety and Immunogenicity Study of Recombinant Human C1 Inhibitor for the Treatment of Acute HAE Attacks

Hereditary Angioedema

United States, Bulgaria, Canada, Hungary, Israel, Italy, Macedonia, The Former Yugoslav Republic of, Poland, Romania, Serbia, South Africa
Andrew Carr
Merck Sharp & Dohme LLC

Completed

Raltegravir Use as Nonoccupational Postexposure Prophylaxis (NPEP) in Men Who Have Sex With Men (RAL-NPEP)

HIV Infections | HIV Prevention

Australia
Sanofi

Completed

Efficacy and Safety of Volinanserin on Sleep Maintenance Insomnia - Polysomnographic Study (NOCTURNE907)

Sleep Initiation and Maintenance Disorders

United States, France, Russian Federation, Germany, Austria, Canada, Australia
Beckman Coulter, Inc.

Completed

Use of Blood Biomarkers and Biomarker Index to Aid in the Diagnosis of Obstructive Sleep Apnea (OSA)

Obstructive Sleep Apnea

United States
PENTA Foundation
Institut National de la Santé Et de la Recherche Médicale, France; MRC CTU... and other collaborators

Completed

Strategy for Maintenance of HIV Suppression With Once Daily Integrate Inhibitor+Darunavir/Ritonavir in Children (SMILE)

HIV Infection

United Kingdom, Spain, Argentina, France, Mexico, Portugal, South Africa, Switzerland, Thailand, Uganda, Ukraine
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

A Study of Single-Dose Gabapentin in Transient Insomnia Induced by a Sleep Phase Advance

Transient Insomnia

United States
Grifols Therapeutics LLC

Enrolling by invitation

Long Term Safety of Alpha1-Proteinase Inhibitor in Subjects With Alpha1 Antitrypsin Deficiency (SPARTA-OLE)

Pulmonary Emphysema in Alpha-1 Antitrypsin Deficiency

United States, New Zealand, Denmark, Australia, Finland, Estonia, Canada, Poland, Russian Federation, Sweden, France
Kirby Institute

Completed

Raltegravir and Atazanavir Dosing Strategy Study (SPARTA)

HIV Infection

Australia
Medical University of South Carolina

Recruiting

Steroids and Pain Control After Tonsillectomy

Tonsillitis | Obstructive Sleep Apnea of Child

United States
ResMed

Completed

Evaluating the Efficacy of PAP Therapy for Treating OSA in the Home Environment

Obstructive Sleep Apnea (OSA)

United States, Australia
FRESCA Medical

Completed

Non-Inferiority Study of the FRESCA Airbox Positive Airway Pressure System

Sleep Apnea

United States
National Institute of Allergy and Infectious Diseases...

Active, not recruiting

Safety of and Immune Response to Dolutegravir in HIV-1 Infected Infants, Children, and Adolescents

HIV Infections

United States, Botswana, Brazil, Kenya, South Africa, Tanzania, Thailand, Zimbabwe
Kirby Institute
Merck Sharp & Dohme LLC; amfAR, The Foundation for AIDS Research; Abbott

Completed

A Trial of 2 Options for Second Line Combination Antiretroviral Therapy Following Virological Failure of a Standard Non-nucleoside Reverse Transcriptase Inhibitor (NNRTI)+2N(t)RTI First Line Regimen (SECOND-LINE)

HIV Infections

Taiwan, Australia, Argentina, Singapore, India, France, South Africa, Chile, Germany, Hong Kong, Ireland, Malaysia, Mexico, New Zealand, Nigeria, Peru, United Kingdom
Woolcock Institute of Medical Research
National Health and Medical Research Council, Australia

Enrolling by invitation

The Effect of OSA on Brain Waste Clearance

Cognitive Impairment | Obstructive Sleep Apnea | Dementia

Australia
Baxalta now part of Shire

Completed

GLASSIA Safety, Immunogenicity, and Bronchoalveolar Lavage Study

Alpha1-antitrypsin Deficiency

United States, Canada

Clinical Trials on Intrinsic Sphincter Deficiency in South Africa

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Myanmar

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations