Clinical Trials on Invasive Malignancy (Any Type)

Total 57216 results

Centre Hospitalier Universitaire Vaudois

Unknown

Breakthrough Invasive Mold Infections Under Posaconazole Prophylaxis (BIMI) (BIMI)

Hematologic Diseases | Hematologic Malignancy | Invasive Mold Infections | Breakthrough Invasive Mold Infections

Switzerland, Austria, Germany
Jan-Willem C Alffenaar
UMC Utrecht; Erasmus Medical Center; Amsterdam UMC, location VUmc; Academisch Medisch... and other collaborators

Completed

Pharmacologic Optimization of Voriconazole (VORI911)

Invasive Fungal Infection | Hematological Malignancy

Netherlands
Robert Krause, MD

Completed

Prospective Clinical Evaluation of Beta-D-Glucan Assay in Blood and BAL

Invasive Fungal Infection | Hematological Malignancy | Receipt of Solid Organ Transplant

Austria
Vanderbilt-Ingram Cancer Center

Active, not recruiting

COVID-19 and Cancer Consortium Registry (CCC19)

COVID-19 | Invasive Malignancy (Any Type)

United States
Melbourne Health
Merck Sharp & Dohme LLC

Recruiting

Posaconazole Pharmacokinetics in Patients Receiving Chemotherapy or Stem Cell Transplants (POPULAR)

Fungal Infection | Pharmacokinetics | Invasive Aspergillosis | Prophylaxis | Invasive Candidiases | Posaconazole | Invasive Mycosis

Australia
University of Cologne

Recruiting

ECMM Candida Registry - CandiReg (CandiReg)

Invasive Candidiases

Germany
Medical University of Graz
Barmherzige Brueder Marschallgasse / Graz

Completed

Influence of Open and Laparoscopic Abdominal Surgery Involving the Intestinal Tract on Serum 1,3-ß-D-Glucan (BDG) Values

Invasive Candidiases

Austria
CSPC Ouyi Pharmaceutical Co., Ltd.

Not yet recruiting

A Study of ABCD for Injection in Subjects With Invasive Candidiasis and Invasive Aspergillus

Invasive Aspergillosis | Invasive Candidiasis

China
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Unknown

Amphotericin B Cholesteryl Sulfate Complex for Injection(ABCD) in the Treatment of Invasive Candidiasis and Invasive Aspergillosis

Invasive Aspergillosis | Invasive Candidiasis
Duke University
National Institute of Allergy and Infectious Diseases (NIAID); Children's Hospital...

Completed

PEACE: Pediatric Antifungal Comparative Effectiveness (PEACE)

Pediatric Invasive Candidiasis

United States, Colombia, Canada, India, Saudi Arabia, Greece, Italy, Spain
Centre Hospitalier Universitaire Dijon

Completed

Evaluate the Performance of Genetic Amplification by Polymerase Chain Reaction (PCR) and the "Mannan Antigenemia and Antimannan Antibodies Couple as a Means of Diagnosis and a Marker of Follow-up in Invasive Candidiasis. (EMPIRICAND)

Invasive Candidiasis; Treatment With Echinocandin

France
Fox Chase Cancer Center
Janssen Pharmaceuticals

Not yet recruiting

Increasing Pre-Surgical Identification of Muscle Invasive Tumor Evaluations Prior to Planned Cystectomy (INSITE) (INSITE)

Urothelial Carcinoma | Non-Muscle Invasive Bladder Urothelial Carcinoma | Muscle Invasive Bladder Urothelial Carcinoma

United States
Duke University

Terminated

Procedural Outcomes in Endobronchial Ultrasound - Transbronchial Needle Aspiration (EBUS-TBNA) With and Without Rapid On-Site Evaluation (ROSE) (ROSE)

ENDOBRONCHIAL ULTRASOUND - TRANSBRONCHIAL NEEDLE ASPIRATION | Benign and Malignant Mediastinal and Hilar Lymph Nodes Known or Suspected Malignancy

United States
University of Bologna

Unknown

A B-D-Glucan Driven Antifungal Stewardship Approach for Invasive Candidiasis

Invasive Candidiases | Abdominal Infection

Italy
Assistance Publique - Hôpitaux de Paris
Institut Pasteur, Paris France

Completed

PET/CT Guided Antifungal Stewardship in Invasive Pulmonary Aspergillosis (OPTIFIL)

Aspergillosis and Haematological Malignancy

France
Clinique Beau Soleil
Cepheid; Team Languedoc Mutualité / Nouvelles technologies

Completed

Diagnostic Performance Evaluation Study of the Xpert® Bladder Cancer Monitor Test. (Xpert Bladder)

Non-Invasive Bladder Urothelial Carcinoma | Non-Invasive Bladder Papillary Urothelial Carcinoma, Low Grade | Non-Invasive Bladder Papillary Urothelial Carcinoma, High Grade

France
M.D. Anderson Cancer Center
National Cancer Institute (NCI); Texas Appropriation for Rare and Aggressive...

Recruiting

Biospecimen and Medical Data Collection and Tumor Biopsy in Creating Research Tissue Registry in Patients With Inflammatory or Invasive Breast Cancer

Invasive Breast Carcinoma | Inflammatory Breast Carcinoma | Second Primary Malignant Neoplasm

United States
University Hospital, Lille

Recruiting

Early Discontinuation of Empirical Antifungal Therapy and Biomarkers (SEAT)

Invasive Candidiasis

France
University Hospital, Limoges

Completed

Pharmacokinetics of Micafungin in Patients of Intensive Care Units (MI-K)

Invasive Candidiasis

France
University Medical Center Groningen

Completed

Variability of Fluconazole Concentration in Critically Ill Patients

Invasive Candidiasis

Netherlands
Merck Sharp & Dohme LLC

Completed

A Multicenter, Randomized, Double-Blind, Comparative Study to Evaluate the Safety, Tolerability, and Efficacy of 2 Dosing Regimens of an Antifungal Drug in the Treatment of Fungal Infections in Adults (0991-801)(COMPLETED)

Invasive Candidiasis
Merck Sharp & Dohme LLC
Mycoses Study Group

Terminated

Pilot Feasibility Study With Patients Who Are at High Risk For Developing Invasive Candidiasis in a Critical Care Setting (MK-0991-067)

Invasive Candidiasis
University Hospital, Grenoble

Completed

Empirical Antifungal Treatment in ICUS (EMPIRICUS)

Invasive Candidiasis

France
Mycoses Study Group
Merck Sharp & Dohme LLC

Completed

Randomized Study of Caspofungin Prophylaxis Followed by Pre-emptive Therapy for Invasive Candidiasis in the Intensive Care Unit (ICU) (MSG-01)

Invasive Candidiasis

United States
Yung Shin Pharm. Ind. Co., Ltd.

Completed

Evaluate Bioequivalence of Micafungin (50mg/Vial)

Invasive Candidiasis

Taiwan
Duke University
Children's Hospital of Philadelphia

Completed

BIOPIC: Fungal Biomarkers for Diagnosis and Response to Therapy for Pediatric Candidemia (BIOPIC)

Invasive Candidiasis

United States, Saudi Arabia, Greece, Spain
Merck Sharp & Dohme LLC

Terminated

Safety, Tolerability, and Efficacy of Caspofungin Versus Amphotericin B Deoxycholate in the Treatment of Invasive Candidiasis in Neonates and Infants (MK-0991-064)

Candidiasis, Invasive
Hasan Al-Dorzi
King Fahad Medical City

Completed

Invasive Candidiasis in Saudi ICUs (ICIP-SA)

Invasive Candidiasis

Saudi Arabia
Pfizer
Vicuron Pharmaceuticals

Completed

The Safety and Effectiveness of Intravenous Anidulafungin as a Treatment for Patients With Invasive Candidiasis.

Candidiasis

United States
University Medical Center Groningen

Completed

Optimal Dosage of Caspofungin in Critically Ill Patients

Critically Ill | Suspected Invasive Candidiasis

Netherlands
Medical University of Graz
Medical University Innsbruck

Completed

NOBICS - NOvel BIomarker In Invasive CandidiasiS/Candida Sepsis (NOBICS)

Invasive Candidiasis

Austria
Fadoi Foundation, Italy

Terminated

Comparison of Two Diagnostic Tests in Patients With Suspected Invasive Candidiasis in Internal Medicine Wards and Who Are Currently Timely Treated With Micafungin (EPICA1)

Invasive Candidiasis

Italy
Kevin Watt

Completed

Pharmacokinetics of Micafungin in Children on Extracorporeal Membrane Oxygenation

Invasive Candidiasis

United States
Duke University
Pfizer

Completed

β-D-Glucan (BDG) Surveillance With Preemptive Anidulafungin vs. Standard Care for Invasive Candidiasis in Surgical Intensive Care Unit (SICU) Patients

Invasive Candidiasis

United States
Hospital Universitario La Fe

Completed

Predictive Factors of Mortality in Invasive Fungal Disease in Post-surgical Critical Care Unit (FPR-IIS)

Fungal Invasive Disease

Spain
Astellas Pharma Inc

Completed

A Study to Evaluate Pre-emptive Treatment for Invasive Candidiasis in High Risk Surgical Subjects (INTENSE)

Mycoses

Belgium, Germany, Spain, France, Italy, Turkey, Austria, Switzerland, Hungary, United Kingdom, Israel, Denmark, Greece, Finland, Romania
Robert Krause, MD

Completed

Candida Spp. in the Lower Respiratory Tract: Harmless Residents or Pathogen?

Invasive Candidiasis | Pulmonary Candidiasis

Austria
The Netherlands Cancer Institute

Completed

Olaparib and Radiotherapy in Inoperable Breast Cancer

Locally Advanced Malignant Neoplasm | Triple-Negative Invasive Breast Carcinoma | Inflammatory Breast Carcinoma

Netherlands
Services Institute of Medical Sciences, Pakistan

Completed

Efficacy of Prophylactic Fluconazole Therapy in Preterm and Very Low Birth Weight Neonates in Preventing Invasive Fungal Infection.

Invasive Candidiases

Pakistan
Pfizer

Completed

An Open-label Study of APX001 for Treatment of Patients With Candidemia/Invasive Candidiasis Caused by Candida Auris (APEX)

Candidemia | Candida Infection | Invasive Candidiases

South Africa
Celgene

Completed

Influence of Rifampin on the Pharmacokinetics of Romidepsin in Patients With Advanced Cancer

Hematologic Malignancy | Malignant Lymphoma

United States, United Kingdom
Cidara Therapeutics Inc.

Completed

Study of Rezafungin Compared to Caspofungin in Subjects With Candidemia and/or Invasive Candidiasis (ReSTORE)

Mycoses | Candidemia | Fungal Infection | Invasive Candidiases

United States, Israel, Spain, Korea, Republic of, Taiwan, Singapore, Thailand, Australia, China, Turkey, Belgium, Germany, France, Argentina, Bulgaria, Colombia, Greece, Italy
Mayo Clinic

Recruiting

The Role Of Interferon-gamma In Immune Responses To Invasive Candidiasis

Candidiasis | Fungal Infection

United States
Merck Sharp & Dohme LLC

Completed

A Study of Caspofungin Acetate (MK0991) for the Treatment of Esophageal Candidiasis or Invasive Candidiasis in Chinese Adults (MK-0991-066)

Fungal Infection
Celgene

Completed

Influence of Ketoconazole on the Pharmacokinetics of Romidepsin in Patients With Advanced Cancer

Hematologic Malignancy | Malignant Lymphoma

United States, United Kingdom
Aura Biosciences

Recruiting

A Phase 1, Open-label Trial of Belzupacap Sarotalocan (AU-011) in Bladder Cancer

Muscle-Invasive Bladder Carcinoma | Non-muscle-invasive Bladder Cancer

United States
Fujian Shengdi Pharmaceutical Co., Ltd.

Recruiting

A Trial of Intravenous HRS9432 in the Treatment of Subjects With Candidemia and/or Invasive Candidiasis

Patients With Candidemia and/or Invasive Candidiasis

China
European Organisation for Research and Treatment...
ETOP IBCSG Partners Foundation

Completed

SPECTAlung: Screening Patients With Thoracic Tumors for Efficient Clinical Trial Access (SPECTAlung)

Any Stage of Lung Cancer (Any Histotype) | Any Stage of Malignant Pleural Mesothelioma | Any Stage of Any Thymic Malignancy

Spain, Belgium, Ireland, Slovenia, France, United Kingdom, Poland, Italy, Switzerland
University Medical Center Groningen

Completed

Pharmacokinetics of Micafungin in Critically Ill Patients

Critical Illness | Invasive Candidiasis

Netherlands
Emory University
National Cancer Institute (NCI); National Institutes of Health (NIH)

Completed

Utility of Perfusion MRI to Detect Radiation Necrosis in Patients With Brain Metastases

Metastatic Malignant Neoplasm in the Brain | Invasive Malignant Neoplasm

United States

Clinical Trials on Invasive Malignancy (Any Type)

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