Clinical Trials on JAK Inhibitor

Total 1686 results

American Thrombosis and Hemostasis Network
LFB USA, Inc.

Recruiting

SEVENFACT® for Bleeding Events in Hemophilia With Inhibitors

Hemophilia A With Inhibitor | Hemophilia B With Inhibitor

United States
CSL Behring

Completed

Extension Study of Zemaira® i.v. Administration in Subjects With Emphysema Due to alpha1-proteinase Inhibitor Deficiency.

Emphysema | Alpha 1-proteinase Inhibitor Deficiency

Australia, Canada, Czech Republic, Denmark, Estonia, Finland, Germany, Ireland, Poland, Romania, Sweden
Assiut University

Not yet recruiting

Synergistic Effect of Plasmid Inhibitors and Antimicrobial Drugs Against Clinical MDR-hvKP

Synergy Between Plasmid Inhibitors and Combined Antibiotics
Wake Forest University

Completed

Endogenous Pain Facilitation and Inhibition in Postpartum Women

Pain Inhibition and Facilitation in Post Partum Women

United States
Pharvaris Netherlands B.V.

Completed

Dose-ranging Study of Oral PHA-022121 for Acute Treatment of Angioedema Attacks in Patients With Hereditary Angioedema (RAPIDe-1)

Hereditary Angioedema | Hereditary Angioedema Type I | Hereditary Angioedema Type II | Hereditary Angioedema Types I and II | Hereditary Angioedema Attack | Hereditary Angioedema With C1 Esterase Inhibitor Deficiency | Hereditary Angioedema - Type 1 | Hereditary Angioedema - Type 2 | C1 Esterase Inhibitor... and other conditions

Bulgaria, United States, Spain, Israel, Germany, Canada, Czechia, France, Hungary, Italy, Netherlands, Poland, United Kingdom
Sun Jia

Completed

Effect of Dapagliflozin on Body Weight in Overweight Women Consuming Different Proportions of Carbohydrate Diet.

Overweight | Carbohydrate | Sodium-glucose Transporter 2 Inhibitors

China
Maastricht University Medical Center

Unknown

Management and Outcomes of Anti-thrombotic Medication Use in Thrombocytopenia (MATTER)

Hematologic Neoplasms | Thrombocytopenia | Anticoagulants | Platelet Aggregation Inhibitors

Netherlands, Italy, Israel, United States
Tatyasaheb Kore Dental College

Completed

EFFECT OF SELECTIVE COX-2 INHIBITOR (ETORICOXIB) ALONG WITH SCALING AND ROOT PLANING (SRP) ON CLINICAL PARAMETERS AND SALIVARY LEVEL OF SUPEROXIDE DISMUTASE IN CHRONIC GENERALIZED PERIODONTITIS A DOUBLE-BLIND, PLACEBO-CONTROLLED, DOUBLE-MASKED RANDOMIZED CONTROLLED TRIAL (RCT).

Periodontitis | Saliva | Cyclooxygenase Two Inhibitors | Etoricoxib | Superoxide Dismutase

India
Mansoura University

Completed

Aromatase Inhibitors or GnRH-a for Uterine Adenomyosis

the Efficacy of Aromatase Inhibitor vs. Gonadotrpins Releasing Hormone Agonists in Treating Premenopausal Women With Uterine Adenomyosis

Egypt
Novo Nordisk A/S

Active, not recruiting

Research Study to Look at How Well the Drug Concizumab Works in Your Body if You Have Haemophilia Without Inhibitors (explorer8)

Haemophilia A Without Inhibitors | Haemophilia B Without Inhibitors

Spain, United States, Korea, Republic of, United Kingdom, Australia, Lithuania, France, Turkey, India, Estonia, Russian Federation, Ukraine, Mexico, Japan, Serbia, Canada, Croatia, Algeria, Bosnia and Herzegovina, Bulgaria, Denmark and more
Laboratoire français de Fractionnement et de Biotechnologies
LFB USA, Inc.

Completed

A Phase III Study on the Safety, Pharmacokinetics and Efficacy of Coagulation Factor VIIa (PERSEPT2)

Hemophilia A With Inhibitors | Hemophilia B With Inhibitors

Bulgaria, Ukraine, Czechia, United States, Georgia, South Africa
Vigonvita Life Sciences

Completed

A Study of the Hemodynamic Interactions of TPN171H Tablets & Alcohol in Healthy Male Subjects

Erectile Dysfunction | Alcohol | Phosphodiesterase Inhibitor

China
Beth Israel Deaconess Medical Center

Completed

Evaluation of Ubiquinol on Mitochondrial Oxidative Capacity in Statin Patients Using 31PMRS

Hypercholesterolemia | Myopathy | HMG COA Reductase Inhibitor Adverse Reaction

United States
Rigshospitalet, Denmark

Completed

Acute Exercise and NK Cell Regulation in Tissue and Circulation After IL-6R Blockade

Appetitive Behavior | Physical Stress | Interleukin-6 Inhibition

Denmark
Hartford Hospital
National Heart, Lung, and Blood Institute (NHLBI)

Completed

The Effect of Statin Medications on Muscle Performance (The STOMP Study) (STOMP)

Muscular Diseases | Hydroxymethylglutaryl-CoA Reductase Inhibitors

United States
Washington University School of Medicine
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National...

Completed

Tauroursodeoxycholic Acid for Protease-inhibitor Associated Insulin Resistance

Endoplasmic Reticulum Stress | HIV Related Insulin Resistance | Protease Inhibitor Related Insulin Resistance

United States
Ospedale Maggiore Di Trieste

Unknown

Immune Checkpoint Inhibitors and Radiotherapy in Relapsed/Refractory Hodgkin Lymphoma (ICI-RT-1)

Hodgkin Lymphoma | Radiotherapy | Immune Checkpoint Inhibitor

Italy
University of Utah
Kaiser Permanente

Not yet recruiting

A Tool to Help Patients With Muscle Symptoms After Taking a Statin Medication.

Cardiovascular Diseases | Hypercholesterolemia | Placebo Effect | Pharmacists | Hydroxymethylglutaryl-CoA Reductase Inhibitors
National Institutes of Health Clinical Center (CC)

Completed

The Influence of Ritonavir, Alone and in Combination With Lopinavir, on Fenofibric Acid Pharmacokinetics in Healthy Volunteers

HIV | Hypertriglyceridemia | Fenofibrate | Protease Inhibitors | Glucuronosyltransferase

United States
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

A Phase Ib/II Study Confirmed Inhibition of Autophagy Synergizes Anti-tumor Effect of High Dose CDK4/6i

Inhibition of Autophagy Synergizes Anti-tumor Effect

China
Oregon State University

Terminated

The Effects of Kinesio Tape® on Arthrogenic Muscle Inhibition and Rate of Torque Development

Neural Inhibition | Injuries, Ankle

United States
Nanfang Hospital, Southern Medical University

Recruiting

Prospective Study on the Efficacy and Safety of Bronchoalveolar Lavage Combined With Pathogen Metagenomic Sequencing Technology in the Diagnosis of Immune Checkpoint Inhibitor Associated Pneumonia

Immune Checkpoint Inhibitor Associated Pneumonia

China
Xiang Xie
Xinjiang Medical University

Not yet recruiting

Study on the Composite Endpoint Event of PCSK9 Inhibitor in Patients With Very High Risk of ASCVD and Cancer

Cancer | Atherosclerotic Cardiovascular Disease | ASCVD | Proprotein Convertase Subtilisin/Kexin Type 9 Inhibitor
Tanta University

Not yet recruiting

Empagliflozin Addition in Modulating Metabolic Disturbances Associated With Olanzapine in Schizophrenia Patients

Sodium-glucose Transport Protein Two Inhibitor (SGLT2),Metabolic Deficits Caused by Antipsychotics
Blueprint Medicines Corporation

Active, not recruiting

(SYMPHONY) Phase 1/2 Study Targeting EGFR Resistance Mechanisms in NSCLC

Neoplasms | Neoplasms by Histologic Type | Lung Diseases | Neoplasms by Site | Adenocarcinoma | Carcinoma | Carcinoma, Non-Small-Cell Lung | Lung Neoplasms | Respiratory Tract Neoplasms | Thoracic Neoplasms | Carcinoma, Bronchogenic | Bronchial Neoplasms | Neoplasms, Nerve Tissue | EGF-R Positive Non-Small Cell Lung... and other conditions

United States, Canada, Taiwan, Korea, Republic of, Singapore, Japan, United Kingdom, France, Netherlands, Spain
CSL Behring

Terminated

Study of Recombinant Factor VIIa Fusion Protein (rVIIa-FP, CSL689) for On-demand Treatment of Bleeding Episodes in Patients With Hemophilia A or B With Inhibitors

Hemophilia A With Inhibitors | Hemophilia B With Inhibitors

Georgia, Italy, Malaysia, Russian Federation, South Africa, Spain, Thailand, Ukraine, United Kingdom
Shanghai Jiao Tong University School of Medicine

Completed

Inductive Camrelizumab and Apatinib for Patients With Locally Advanced and Resectable Oral Squamous Cell Carcinoma

Oral Cancer | VEGFR2 Inhibitor | Programmed Cell Death 1 Inhibitor | Inductive Therapy

China
Population Council

Unknown

A Study to Evaluate the Effect of a Contraceptive Vaginal Ring Delivering Ulipristal Acetate Combined With a Single or Repeated Levonorgestrel on Inhibition of Ovulation, Endometrial Changes and Bleeding Patterns in Normal Cycling Women

Ovulation Inhibition

Dominican Republic
Universidad Rey Juan Carlos

Completed

Neural Tensioner Exercise on Conditioned Pain Modulation

Neck Pain | Diffuse Noxious Inhibitory Control

Spain
Insel Gruppe AG, University Hospital Bern
Sahajanand Medical Technologies Limited

Recruiting

Monotherapy With P2Y12 Inhibitors in Patients With Atrial fIbrillation Undergoing Supraflex Stent Implantation (MATRIX-2)

Atrial Fibrillation (AF) | Oral Anticoagulation | Percutaneous Coronary Intervention (PCI) | P2Y12 Inhibitor

Spain, France, Switzerland, United Kingdom, Germany, Belgium, Italy, Netherlands, Poland
Radboud University Medical Center

Completed

Physical Activity Levels and Statin Therapy

Cardiovascular Diseases | Muscle Pain | HMG COA Reductase Inhibitor Adverse Reaction

Netherlands
Asan Medical Center

Completed

Study of Vorinostat Plus Capecitabine (X) and Cisplatin (P) for 1st Line Treatment of Metastatic or Recurrent Gastric Cancer: Zolinza+XP

Gastric Cancer | Histone Deacetylase Inhibitor

Korea, Republic of
University of Bern

Recruiting

Neuropsychological Patterns of Suicide Ideators and Suicide Attempters (NePsyAssip HT)

Suicidal Ideation | Suicide, Attempted | Self Efficacy | Attention | Locus of Control | Inhibitory Control

Switzerland
The National Center of Oncology, Azerbaijan
SOFIE INC

Recruiting

Comparison of [68Ga]GaFAPI-46 PET/CT and [18F]FDG PET/CT Findings in Breast Carcinoma

Breast Neoplasms | Positron Emission Tomography | Fluorodeoxyglucose F18 | Fibroblast Activation Protein Inhibitor

Azerbaijan
TC Erciyes University

Unknown

Effects of Enteral Nutrition on Stress Ulcer Hemorrage. Multicenter Randomized Controlled Trial

Enteral Nutrition | Stress Ulcer Prophylaxis | Proton Pump Inhibitor | Gastro Intestinal Bleeding

Turkey
Novo Nordisk A/S

Completed

A Study Following People With Haemophilia A and B, With or Without Inhibitors, When on Usual Treatment (Explorer™6) (explorer™6)

Haemophilia A With Inhibitors | Haemophilia B With Inhibitors | Haemophilia A | Haemophilia B

France, United States, India, Mexico, United Kingdom, Netherlands, Sweden, Korea, Republic of, Spain, Switzerland, Serbia, Turkey, Bulgaria, Italy, Japan, Poland, South Africa, Croatia, Algeria, Australia, Bosnia and Herzegovina, ... and more
University of Vienna

Completed

Yoga Practice, Stress and Cognitive Performance

Stress | Anxiety | Inhibition | Attentional Control Switching | Task Switching Between Modalities

Austria
First People's Hospital of Hangzhou

Recruiting

A RCT of the Efficacy of Vonoprazan 20mg QD in the Treatment of Helicobacter Pylori Infection (VATH-1)

Helicobacter Pylori Infection | Proton Pump Inhibitor | Vonoprazan

China
Zhejiang Cancer Hospital

Recruiting

Dalpiciclib Combination With Fulvestrant and Compound Gossyfol Acetate Tablets in Women With CDK4/6 Inhibitor-refractory HR-positive HER-2 Negtive Metastatic Breast Cancer: a Phase 2 Clinical Trial.

Advanced HR-positive and HER2-negative Breast Cancer; CDK4/6 Inhibitor Treatment Failed

China
Henan Cancer Hospital

Recruiting

Toripalimab Plus FLOT in Locally Advanced Gastric Cancer

Chemotherapy | Immune Checkpoint Inhibitor | Locally Advanced Gastric Carcinoma

China
Vanderbilt University Medical Center
Shire

Terminated

Effect of Bradykinin Receptor Antagonism on ACE Inhibitor-associated Angioedema

ACE Inhibitor-associated Angioedema

United States
Sohag University

Completed

First-time Usage of SGLT2 Inhibitors in Type 2 Diabetic Patients Who Are Fasting During Ramadan: Safety and Efficacy

Type2 Diabetes | SGLT2 Inhibitors, First Time Use | Fasting in Ramadan

Egypt
Inova Health Care Services

Completed

Pharmacodynamics and Pharmacokinetics of Aspirin Inhalation Powder With Non-Enteric-Coated Chewable Aspirin

Platelet Aggregation Inhibitors

United States
R&D Cardiologie

Completed

WOEST ( What is the Optimal antiplatElet & Anticoagulant Therapy in Patients With Oral Anticoagulation and Coronary StenTing) (WOEST)

Atrial Fibrillation | Stents | Anticoagulants | Platelet Aggregation Inhibitors

Netherlands, Belgium
Sichuan University

Recruiting

Safety and Efficacy of Whole Brain LDRT+ICI+Intrathecal Chemotherapy in Refractory Meningeal Metastasis of Lung Cancer

NSCLC | PD-1 Inhibitor | Leptomeningeal Metastasis | Low Dose Radiotherapy

China
Fudan University

Recruiting

Sintilimab Combined With Modified FLOT Regimen in the Treatment of Metastatic Gastric Cancer

Gastric Cancer | Chemotherapy Effect | Immune Checkpoint Inhibitor

China
Peking Union Medical College Hospital
Geneplus-Beijing Co. Ltd.

Active, not recruiting

Exploratory Study on the Therapeutic Effect Prediction Model of Advanced BTC Immunotherapy

Biliary Tract Cancer | Predictive Cancer Model | Immune Checkpoint Inhibitor

China
Novo Nordisk A/S

Active, not recruiting

Research Study to Look at How Well the Drug Concizumab Works in Your Body if You Have Haemophilia With Inhibitors (explorer7)

Haemophilia A With Inhibitors | Haemophilia B With Inhibitors

Spain, Korea, Republic of, India, Australia, United Kingdom, Russian Federation, Poland, Ukraine, Thailand, Mexico, United States, Turkey, Japan, South Africa, Serbia, France, Croatia, Denmark, Algeria, Bulgaria, Malaysia, Portugal, Slovaki... and more
rEVO Biologics
Laboratoire français de Fractionnement et de Biotechnologies

Completed

Phase III Study of Coagulation FVIIa (Recombinant) in Congenital Hemophilia A or B Patients With Inhibitors

Hemophilia A With Inhibitors | Hemophilia B With Inhibitors

United States, Bulgaria, Poland, Russian Federation, Belarus, Georgia, Israel, Romania, Ukraine, United Kingdom
Chen Xiaoping

Completed

Postoperative Adjuvant Immunotherapy for Hepatocellular Carcinoma: Risk Factor Analysis and Prognostic Modelling

Hepatocellular Carcinoma | Checkpoint Inhibitor | Adjuvant Immunotherapy

China

Clinical Trials on JAK Inhibitor

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