Clinical Trials on Joint Replacement Surgery in Netherlands

Total 581 results

Centocor, Inc.
Schering-Plough

Completed

A Study of the Safety and Efficacy of Golimumab in Subjects With Active Ankylosing Spondylitis

Spondylitis, Ankylosing

United States, Germany, Finland, Taiwan, Korea, Republic of, Canada, Belgium, Netherlands, France
Galapagos NV

Terminated

A Study to Evaluate the Effects of GLPG2737 in Participants With Autosomal Dominant Polycystic Kidney Disease (ADPKD)

Autosomal Dominant Polycystic Kidney Disease

Belgium, Netherlands, Italy, Spain, Czechia, Germany, Poland
Pfizer

Recruiting

Effectiveness of Treatment With Tofacitinib in Patients With Psoriatic Arthritis in Routine Clinical Practice

Psoriatic Arthritis

Israel, France, Spain, Finland, Netherlands, Belgium, Denmark, Sweden
Janssen Research & Development, LLC
Schering-Plough

Terminated

A Study of the Safety and Efficacy of CNTO 148 (Golimumab) in Children With Juvenile Idiopathic Arthritis (JIA) and Multiple Joint Involvement Who Have Poor Response to Methotrexate (GO KIDS)

Juvenile Idiopathic Arthritis

Poland, United States, Germany, Belgium, Canada, Finland, Netherlands, Russian Federation, Brazil, Austria, Lithuania, Mexico
Galapagos NV

Active, not recruiting

Prospective Observational Study of Filgotinib in Subjects With Rheumatoid Arthritis (FILOSOPHY)

Rheumatoid Arthritis

Belgium, Netherlands, Spain, Germany, Italy, United Kingdom
Amgen

Completed

Phase II Study of Apremilast (CC-10004) in Adults With in Psoriatic Arthritis

Psoriatic Arthritis

Belgium, Canada, United Kingdom, Germany, Netherlands
GlaxoSmithKline

Terminated

Investigating Clinical Efficacy of Ofatumumab in Adult Rheumatoid Arthritis (RA) Patients Who Had an Inadequate Response to TNF-α Antagonist Therapy

Arthritis, Rheumatoid

Italy, Argentina, Germany, Peru, Korea, Republic of, Denmark, Spain, Sweden, France, Netherlands, Norway, United Kingdom
Pfizer

Completed

Study Comparing Etanercept (ETN) Against a Placebo for Etanercept on a Background Nonsteroidal Anti Inflammatory Drug (NSAIDs) in the Treatment of Early Spondyloarthritis (SpA) Patients Who do Not Have X-ray Structural Changes (EMBARK)

Spondylitis, Ankylosing

Belgium, Korea, Republic of, Spain, France, Taiwan, Germany, Argentina, Czech Republic, United Kingdom, Hungary, Russian Federation, Colombia, Finland, Netherlands
Bristol-Myers Squibb

Completed

Phase I/II Multiple-Dose LEA29Y vs CTLAG4Ig vs Placebo in Rheumatoid Arthritis

Rheumatoid Arthritis

United States, Netherlands, Belgium, Canada, Germany, France, Ireland, Switzerland, United Kingdom
Daiichi Sankyo, Inc.

Completed

Study to Evaluate Discontinuation and Re-Treatment in Participants With Tenosynovial Giant Cell Tumor (TGCT) Previously Treated With Pexidartinib (PLX3397)

Tenosynovial Giant Cell Tumor

United States, Spain, Taiwan, Australia, Hungary, Italy, Netherlands
Hoffmann-La Roche

Completed

A Study of Rituximab (MabThera®/Rituxan®) in Patients With Rheumatoid Arthritis and Inadequate Response to Methotrexate (SCORE)

Rheumatoid Arthritis

Germany, Spain, Switzerland, Canada, Estonia, Greece, France, Russian Federation, Netherlands, Turkey, Serbia, Argentina, Latvia, Lithuania, Denmark, Romania, Brazil, Czech Republic, Norway
Pfizer

Completed

Study Evaluating Etanercept in 3 Subtypes of Childhood Arthritis (CLIPPER)

Arthritis, Juvenile Idiopathic

France, Spain, Serbia, Belgium, Germany, Czech Republic, Colombia, Mexico, Russian Federation, Norway, Italy, Slovenia, Slovakia, Poland, Australia, Hungary, Latvia, Lithuania, Netherlands
Eli Lilly and Company

Completed

A Study of Ixekizumab (LY2439821) in TNF Inhibitor Experienced Participants With Radiographic Axial Spondyloarthritis (COAST-W)

Spondyloarthritis

Italy, Japan, United States, Puerto Rico, Spain, Mexico, Netherlands, France, Poland, Israel, Argentina, Brazil, Canada, Korea, Republic of, Germany, Finland, United Kingdom
Novartis Pharmaceuticals

Completed

Extension in AS: Sustainability of Benefits, Safety and Tolerability (MEASURE 1 ext)

Spondylitis, Ankylosing

Belgium, Germany, Netherlands, France, United States, Bulgaria, Italy, Mexico, Russian Federation, Peru, United Kingdom, Turkey, Canada, Taiwan
Sanofi
Regeneron Pharmaceuticals

Completed

To Evaluate The Safety of SAR153191 (REGN88) and Tocilizumab Added to Other RA Drugs in Patients With RA Who Are Not Responding to or Intolerant of Anti-TNF Therapy (SARIL-RA-ASCERTAIN)

Rheumatoid Arthritis

United States, Argentina, Belgium, Brazil, Czechia, Estonia, Finland, Hungary, Israel, Italy, Mexico, Netherlands, Poland, Romania, Russian Federation, Spain, Sweden, United Kingdom, Norway
Baxter Healthcare Corporation
Apatech, Inc.

Terminated

Bone Graft Materials Observational Registry (APPROACH-001)

Degenerative Disc Disease | Spinal Stenosis | Herniated Disc | Cervical Myelopathy | Spinal Cord Neoplasms | Spinal Deformity | Failed Back Surgery Syndrome | Spondylolithesis

United States, Hungary, Netherlands
Bristol-Myers Squibb

Completed

Abatacept With Methotrexate- Phase IIB

Rheumatoid Arthritis

Belgium, United States, Canada, Germany, United Kingdom, Australia, France, Ireland, Netherlands, Argentina, South Africa
Pfizer
Trubion Pharmaceuticals/Emergent BioSolutions Inc.

Terminated

Study Evaluating 2 Dosing Regimens Of TRU-015 In Rheumatoid Arthritis

Arthritis, Rheumatoid

United States, Germany, Hungary, Serbia, Belgium, France, Netherlands, Mexico, Canada, Romania
Centocor, Inc.
Schering-Plough

Completed

A Study of the Safety and Efficacy of Golimumab (CNTO 148) in Subjects With Active Rheumatoid Arthritis Previously Treated With Biologic Anti-TNFa Agent(s)

Arthritis, Rheumatoid

United States, Australia, United Kingdom, Germany, Spain, Canada, Finland, Austria, New Zealand, Netherlands
Pfizer

Completed

Study Evaluating Etanercept Plus Methotrexate in Early Rheumatoid Arthritis

Active Rheumatoid Arthritis | Arthritis, Rheumatoid | Rheumatoid Arthritis

Italy, Spain, Switzerland, France, Germany, Poland, Netherlands, United Kingdom, Monaco, Romania, Ireland, Qatar, Russian Federation
Pfizer

Completed

Etanercept Withdrawal And Retreament Study In Subjects With Nr-ax SpA (RE-EMBARK)

Spondylitis, Ankylosing

United States, Sweden, Taiwan, Colombia, Hungary, Belgium, Australia, Finland, Netherlands, Spain, Czechia, Poland, France, Germany
Wyeth is now a wholly owned subsidiary of Pfizer

Terminated

A Study Comparing 4 Dose Regimens of PLA-695, Naproxen, and Placebo In Subjects With Osteoarthritis Of The Knee

Osteoarthritis

Poland, Spain, Hong Kong, United States, Canada, Hungary, Netherlands, Brazil, Mexico, Argentina
Pfizer

Completed

Study Comparing Etanercept in Combination With Methotrexate in Subjects With Rheumatoid Arthritis (PRESERVE)

Arthritis, Rheumatoid

Czech Republic, Colombia, Germany, France, Belgium, Spain, Russian Federation, Poland, Australia, Austria, Chile, Former Serbia and Montenegro, Hungary, Italy, Korea, Republic of, Mexico, Netherlands, Sweden, Taiwan, United Kingdom
Hoffmann-La Roche

Completed

A Study of Retreatment With MabThera (Rituximab) in Combination With Methotrexate in Patients With Rheumatoid Arthritis (RA)

Rheumatoid Arthritis

Belgium, France, Germany, Spain, United Kingdom, Australia, Canada, Taiwan, Thailand, China, Hungary, Italy, Netherlands, South Africa, Slovakia, Finland, New Zealand, Brazil
Eli Lilly and Company

Completed

A Study of Ixekizumab (LY2439821) in Participants With Nonradiographic Axial Spondyloarthritis (COAST-X)

Axial Spondyloarthritis

United States, Puerto Rico, Russian Federation, Mexico, Poland, Argentina, Austria, Brazil, Canada, Czechia, Finland, Germany, Japan, Korea, Republic of, Netherlands, Romania
Boehringer Ingelheim

Terminated

Efficacy, Pharmacokinetics, and Safety of BI 695500 in Patients With Rheumatoid Arthritis

Arthritis, Rheumatoid

United States, United Kingdom, Netherlands, Ireland, Argentina, Poland, Mexico, Spain, Bulgaria, Chile, Germany, Ukraine, Portugal, Belgium, Canada, Greece, Hungary
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating Etanercept and Sulphasalazine in Ankylosing Spondylitis

Ankylosing Spondylitis

France, Poland, Italy, Germany, Spain, United Kingdom, Denmark, Austria, China, Ireland, Hungary, Finland, Netherlands, Australia, Czech Republic, Qatar, Saudi Arabia, Sweden
Centocor Ortho Biotech Services, L.L.C.
Schering-Plough

Completed

RESTART C0168Z05 Rheumatoid Arthritis Study

Rheumatoid Arthritis

United States, United Kingdom, Spain, Israel, Finland, Canada, France, Austria, Germany, Netherlands
Pfizer

Completed

Study Comparing Perceptions and Satisfaction for Two Different Delivery Mechanisms for Etanercept

Rheumatoid Arthritis

France, Germany, Italy, Sweden, United Kingdom, Netherlands, Denmark, Finland, Norway
Hoffmann-La Roche
Biogen

Completed

A Study of the Efficacy and Safety of Re-treatments With Rituximab in Patients With Active Rheumatoid Arthritis Who Have Had an Inadequate Response to Anti-tnfa Therapies

Rheumatoid Arthritis

Belgium, Germany, Norway, United Kingdom, United States, Ireland, France, Canada, Israel, Netherlands, Italy
Merck Sharp & Dohme LLC

Completed

Golimumab (MK-8259 / SCH900259) Treatment Withdrawal in Participants With Non-radiographic Axial Spondyloarthritis (GO-BACK) (MK-8259-038)

Spondyloarthritis

Czechia, Germany, Netherlands, Poland, Romania, Russian Federation, Spain, Turkey, Ukraine
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Comparing Etanercept Plus Methotrexate to Either Etanercept or Methotrexate Alone in Rheumatoid Arthritis.

Active Rheumatoid Arthritis

Australia, Austria, Belgium, Denmark, Finland, France, Germany, Greece, Israel, Italy, Netherlands, Norway, Poland, Portugal, Romania, Spain, Sweden, United Kingdom, Czechia
Novartis Pharmaceuticals

Completed

16 Week Efficacy and 2 Year Long Term Safety and Efficacy of Secukinumab in Patients With Active Ankylosing Spondylitis (MEASURE 1)

Ankylosing Spondylitis

Germany, Belgium, Netherlands, France, United States, Bulgaria, Italy, Russian Federation, Peru, United Kingdom, Canada, Mexico, Taiwan, Turkey
Novartis Pharmaceuticals

Completed

Study of Power Doppler Ultrasound (PDUS) to Measure Response of Secukinumab Treatment in Patients With Active Psoriatic Arthritis (PsA) (PDUS)

Psoriatic Arthritis

Germany, Netherlands, Spain, Argentina, Belgium, Colombia, Italy, United States, United Kingdom, Ireland, France, Mexico, Canada, Austria, Czechia, Hungary, Norway
UCB Biopharma SRL

Completed

A Study to Evaluate the Efficacy and Safety of Bimekizumab in Subjects With Active Ankylosing Spondylitis (BE MOBILE 2)

Ankylosing Spondylitis

United States, Belgium, Bulgaria, China, Czechia, France, Germany, Hungary, Japan, Netherlands, Poland, Spain, Turkey, United Kingdom
Sanofi
Regeneron Pharmaceuticals

Completed

Dose Ranging Study to Evaluate the Efficacy and Safety of SAR153191 (REGN88) in Patients With Ankylosing Spondylitis (ALIGN)

Ankylosing Spondylitis

Germany, Hungary, Belgium, Czechia, Austria, Canada, Lithuania, Poland, Spain, Turkey, France, Netherlands, United States, Australia
Bristol-Myers Squibb

Terminated

Safety and Efficacy of Abatacept Versus Placebo in Participants With Psoriatic Arthritis

Psoriatic Arthritis

Argentina, France, Italy, United States, Canada, Belgium, Netherlands, Australia, Germany, South Africa, Spain, Norway
UCB BIOSCIENCES GmbH

Completed

Certolizumab Pegol in Subjects With Active Axial Spondyloarthritis

Spondyloarthropathies

Germany, United States, Argentina, Belgium, Brazil, Canada, Czechia, France, Hungary, Italy, Mexico, Poland, Spain, United Kingdom, Netherlands
Galapagos NV

Active, not recruiting

A Study Evaluating the Effect of Filgotinib in Participants With Active Axial Spondyloarthritis (OLINGUITO)

Axial Spondyloarthritis

Belgium, Korea, Republic of, Greece, Taiwan, France, Romania, Germany, Netherlands, Italy, Philippines, United Kingdom, Hungary, Estonia, South Africa, Bulgaria, Spain, Croatia, Czechia, Poland, Lithuania
Pfizer

Terminated

Long-Term Analgesic Efficacy And Safety Of Tanezumab Alone Or In Combination With Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) Versus NSAIDs Alone In Patients With Osteoarthritis Of The Knee Or Hip

Arthritis | Osteoarthritis

Netherlands, United States, Korea, Republic of, Colombia, Canada, Philippines, South Africa, Ukraine, India, Mexico, Russian Federation, Spain
Grünenthal GmbH
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.

Completed

A Study to Evaluate the Efficacy and Safety of CG5503 Prolonged Release (PR) in Subjects With Moderate to Severe Chronic Pain Due to Osteoarthritis of the Knee

Pain | Knee Osteoarthritis

Austria, Croatia, Germany, Hungary, Italy, Latvia, Netherlands, Poland, Portugal, Romania, Slovakia, Spain, United Kingdom
Hoffmann-La Roche

Completed

A Study of Tocilizumab and Methotrexate Treatment Strategies (Adding Tocilizumab to Methotrexate Versus Switching to Tocilizumab) in Patients With Active Rheumatoid Arthritis With Inadequate Response to Prior Methotrexate Treatment

Rheumatoid Arthritis

Germany, Norway, Spain, France, Sweden, United States, Estonia, United Kingdom, Greece, Russian Federation, Italy, Denmark, Netherlands, Thailand, Latvia, Croatia, Serbia, Israel, Brazil, Romania
Novartis Pharmaceuticals

Completed

16-week Efficacy and 2-year Safety, Tolerability and Efficacy of Secukinumab in Participants With Active Ankylosing Spondylitis (MEASURE4)

Spondylitis, Ankylosing

Germany, Austria, Denmark, United States, Australia, Netherlands, Poland, Italy, Bulgaria, Spain, Russian Federation, United Kingdom, Greece, Czechia, Canada, Norway, Slovakia, Switzerland, Finland
Eli Lilly and Company

Completed

A Long Term Extension Study of Ixekizumab (LY2439821) in Participants With Axial Spondyloarthritis

Axial Spondyloarthritis

United States, Puerto Rico, Korea, Republic of, Netherlands, Taiwan, Canada, Israel, Spain, Japan, Brazil, Argentina, Hungary, Poland, Czechia, France, Russian Federation, Germany, Mexico, United Kingdom, Romania, Italy, Finland, Au...
UCB BIOSCIENCES GmbH
Parexel

Completed

Study to Evaluate Maintenance of Sustained Remission of axSpA With CZP Compared to Placebo (C-OPTIMISE)

Ankylosing Spondylitis | Axial Spondyloarthrithis

United States, Belgium, Bulgaria, Czechia, France, Germany, Hungary, Netherlands, Poland, Romania, Spain, Taiwan, Turkey, United Kingdom
Bristol-Myers Squibb

Completed

Efficacy and Safety Study of BMS-986142 in Patients With Moderate to Severe Rheumatoid Arthritis

Rheumatoid Arthritis

Japan, Spain, United States, Mexico, Italy, Poland, France, Brazil, Korea, Republic of, Canada, Taiwan, Russian Federation, South Africa, Argentina, Germany, Austria, Netherlands
Hoffmann-La Roche

Terminated

A Study of Tocilizumab (RoActemra/Actemra) in Patients With Ankylosing Spondylitis Who Have Had an Inadequate Response to Previous Tumor Necrosis Factor (TNF) Antagonist Therapy

Spondylitis, Ankylosing

Belgium, Czech Republic, France, Germany, Italy, Spain, United States, Canada, Poland, South Africa, United Kingdom, Australia, Denmark, Netherlands, Bulgaria, India, Lithuania, Brazil, Slovakia
AstraZeneca

Terminated

Evaluation of Efficacy and Safety of Fostamatinib Monotherapy Compared With Adalimumab Monotherapy in Patients With Rheumatoid Arthritis (RA) (OSKIRA -4)

Rheumatoid Arthritis

United States, Bulgaria, Czech Republic, Poland, Russian Federation, South Africa, United Kingdom, Hungary, Ukraine, Germany, Netherlands, Canada, Slovakia
Hoffmann-La Roche

Completed

A Study of RoActemra/Actemra (Tocilizumab) in Patients With Active Systemic Juvenile Idiopathic Arthritis (JIA)

Juvenile Idiopathic Arthritis

Belgium, Italy, Spain, United States, Greece, Germany, Australia, Brazil, Argentina, Canada, United Kingdom, Poland, Denmark, Norway, Mexico, Slovakia, Sweden, Czech Republic, Netherlands
Deciphera Pharmaceuticals LLC

Active, not recruiting

Study of Vimseltinib (DCC-3014) in Patients With Advanced Tumors and Tenosynovial Giant Cell Tumor

Advanced Malignant Neoplasm | Tenosynovial Giant Cell Tumor | Giant Cell Tumor of Tendon Sheath | Pigmented Villonodular Synovitis | Tenosynovial Giant Cell Tumor, Diffuse

United States, France, Spain, United Kingdom, Netherlands, Canada, Italy, Australia, Poland

Clinical Trials on Joint Replacement Surgery in Netherlands

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