Clinical Trials on Kidney Failure, Chronic

Total 48300 results

City of Hope Medical Center
National Cancer Institute (NCI)

Terminated

Total Marrow and Total Lymph Node Irradiation, Fludarabine, and Melphalan Followed By Donor Stem Cell Transplant in Treating Patients With Advanced Hematological Cancer That Has Not Responded to Treatment

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Multiple Myeloma and Plasma Cell Neoplasm | Myelodysplastic/Myeloproliferative Neoplasms

United States
University of California, San Francisco
National Cancer Institute (NCI)

Withdrawn

Busulfan and Fludarabine Before Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Anemia | Multiple Myeloma and Plasma Cell Neoplasm | Myelodysplastic/Myeloproliferative Diseases

United States
University of Kansas

Completed

A Randomized Exercise Trial for Wheelchair Users

Stroke | Multiple Sclerosis | Cerebral Palsy | Arthritis | Muscular Dystrophy | Amputation | Spinal Cord Injury | Spina Bifida

United States
Hoag Memorial Hospital Presbyterian
Cancer Biotherapy Research Group

Completed

Interleukin-2 Plus Interferon Alfa in Treating Adults With Metastatic Cancer

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Unspecified Adult Solid Tumor, Protocol Specific | Multiple Myeloma and Plasma Cell Neoplasm | Precancerous/Nonmalignant Condition

United States
National Cancer Institute (NCI)

Active, not recruiting

Vemurafenib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With BRAF V600 Mutations (A Pediatric MATCH Treatment Trial)

Soft Tissue Sarcoma | Osteosarcoma | Ewing Sarcoma | Malignant Glioma | Ependymoma | Rhabdoid Tumor | Advanced Malignant Solid Neoplasm | Refractory Malignant Solid Neoplasm | Rhabdomyosarcoma | Recurrent Malignant Solid Neoplasm | Recurrent Neuroblastoma | Refractory Neuroblastoma | Refractory Non-Hodgkin Lymphoma and other conditions

United States, Puerto Rico
Incyte Corporation

Active, not recruiting

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099318 in Participants With Advanced Solid Tumors

Cervical Cancer | Nasopharyngeal Carcinoma | Advanced Solid Tumors | Mesothelioma | Small-cell Lung Cancer | Esophageal Squamous Cell Carcinoma | Merkel Cell Carcinoma | Sarcomatoid Renal Cell Carcinoma | Anal Carcinoma | Cutaneous Squamous Cell Carcinoma | MSI-H/dMMR Tumors | PD-L1 Amplified Tumor (9p24.1) | Urothelial... and other conditions

Finland, United States, United Kingdom, Belgium, Sweden, Denmark, Norway
Boston Children's Hospital

Recruiting

Delineating the Molecular Spectrum and the Clinical, Imaging and Neuronal Phenotype of Chopra-Amiel-Gordon Syndrome

Genetic Disease | Chopra-Amiel-Gordon Syndrome | CAGS | ANKRD17

United States
National Human Genome Research Institute (NHGRI)

Completed

Study of People With Generalized Arterial Calcification of Infancy (GACI) or Autosomal Recessive Hypophosphatemic Rickets Type 2 (ARHR2)

Generalized Arterial Calcification of Infancy | Autosomal Recessive Hypophosphatemic Rickets Type2

United States
University of Birmingham

Active, not recruiting

Efficacy and Safety Trial of Sodium Valproate, in Paediatric and Adult Patients With Wolfram Syndrome

Wolfram Syndrome

France, United Kingdom, Poland, Spain
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

Arsenic Trioxide in Treating Patients With Advanced Neuroblastoma or Other Childhood Solid Tumors

Sarcoma | Kidney Cancer | Ovarian Cancer | Brain and Central Nervous System Tumors | Neuroblastoma | Retinoblastoma | Liver Cancer | Extragonadal Germ Cell Tumor | Childhood Germ Cell Tumor

United States
Mayo Clinic
National Cancer Institute (NCI)

Completed

Everolimus and Vatalanib in Treating Patients With Advanced Solid Tumors

Unspecified Adult Solid Tumor, Protocol Specific | Recurrent Melanoma | Stage IV Melanoma | Gastrinoma | Glucagonoma | Insulinoma | Metastatic Gastrointestinal Carcinoid Tumor | Pancreatic Polypeptide Tumor | Recurrent Gastrointestinal Carcinoid Tumor | Recurrent Islet Cell Carcinoma | Somatostatinoma | Stage... and other conditions

United States
National Cancer Institute (NCI)

Terminated

Ibrutinib in Treating Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma in Patients With HIV Infection

HIV Infection | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma | Recurrent Adult Lymphoblastic Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular... and other conditions

United States
Centre d'Etude des Cellules Souches
Genethon

Recruiting

Efficacy Study of Daily Administration of VPA in Patients Affected by Wolfram Syndrome (AUDIOWOLF)

Wolfram Syndrome

France, Spain
Amylyx Pharmaceuticals Inc.

Active, not recruiting

AMX0035 in Adult Patients With Wolfram Syndrome

Wolfram Syndrome

United States
Westfälische Wilhelms-Universität Münster
ICON plc

Unknown

Natural History of GACI With or Without ARHR2 or PXE

Pseudoxanthoma Elasticum | Generalized Arterial Calcification in Infancy | Autosomal Recessive Hypophosphatemic Rickets

Germany
Ospedale San Raffaele

Recruiting

Tirzepatide Monotherapy in Patients With Wolfram Syndrome Type 1

Wolfram Syndrome

Italy
Takeda

Recruiting

A Study of TAK-500 With or Without Pembrolizumab in Adults With Select Locally Advanced or Metastatic Solid Tumors

Kidney Cancer | Breast Cancer | Nasopharyngeal Cancer | Gastric Cancer | Pancreatic Cancer | Esophageal Cancer | Mesothelioma | Hepatocellular Cancer | Squamous Cell Cancer of Head and Neck (SCCHN) | Non-small Cell Lung Cancer (NSCLC), Non-squamous

United States
Washington University School of Medicine

Enrolling by invitation

I-Tracking Neurodegeneration in Early Wolfram Syndrome (I-TRACK)

Wolfram Syndrome

United States
Children's Cancer and Leukaemia Group

Unknown

Polyvinylpyrrolidone-Sodium Hyaluronate Gel in Reducing Pain From Oral Mucositis in Young Patients With Cancer

Sarcoma | Pain | Lymphoma | Kidney Cancer | Unspecified Childhood Solid Tumor, Protocol Specific | Leukemia | Brain and Central Nervous System Tumors | Mucositis | Chordoma | Neuroblastoma

United Kingdom, Ireland
National Institutes of Health Clinical Center (CC)
National Cancer Institute (NCI)

Completed

Ixabepilone in Treating Young Patients With Solid Tumors or Leukemia That Haven't Responded to Therapy

Sarcoma | Kidney Cancer | Unspecified Childhood Solid Tumor, Protocol Specific | Leukemia | Ovarian Cancer | Brain and Central Nervous System Tumors | Neuroblastoma | Liver Cancer | Extragonadal Germ Cell Tumor | Childhood Germ Cell Tumor

United States
National Institutes of Health Clinical Center (CC)
National Cancer Institute (NCI)

Completed

Talabostat Combined With Temozolomide or Carboplatin in Treating Young Patients With Relapsed or Refractory Brain Tumors or Other Solid Tumors

Sarcoma | Kidney Cancer | Unspecified Childhood Solid Tumor, Protocol Specific | Ovarian Cancer | Brain and Central Nervous System Tumors | Neuroblastoma | Liver Cancer | Childhood Germ Cell Tumor

United States
New York Medical College

Completed

Human Placental-Derived Stem Cell Transplantation (HPDSC)

Mucopolysaccharidosis I | Myelodysplastic Syndrome | Acute Lymphocytic Leukemia | Acute Myelogenous Leukemia | Niemann-Pick Disease | Mucopolysaccharidosis VI | Wolman Disease | Adrenoleukodystrophy | Batten Disease | Metachromatic Leukodystrophy | Diamond-Blackfan Anemia | Severe Aplastic Anemia | Fucosidosis | Gaucher... and other conditions

United States
National Cancer Institute (NCI)

Recruiting

A Phase I/II Study of Combination Immunotherapy for Advanced Cancers Including HPV-Associated Malignancies, Small Bowel, and Colon Cancers

Cervical Cancer | Vulvar Cancer | Colon Cancer | Anal Cancer | Vaginal Cancer | Oropharyngeal Cancer | Penile Cancer | HPV | Human Papillomavirus | Neck Cancer

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

CPI-613 and Fluorouracil in Treating Patients With Metastatic Colorectal Cancer That Cannot Be Removed by Surgery

Mucinous Adenocarcinoma of the Rectum | Signet Ring Adenocarcinoma of the Rectum | Stage IIIA Rectal Cancer | Stage IIIB Rectal Cancer | Stage IIIC Rectal Cancer | Mucinous Adenocarcinoma of the Colon | Signet Ring Adenocarcinoma of the Colon | Stage IIIA Colon Cancer | Stage IIIB Colon Cancer | Stage... and other conditions

United States
Asana BioSciences

Completed

A Study of ASN007 in Patients With Advanced Solid Tumors

Cancer | Neoplasm Metastasis | Pancreatic Cancer | Metastatic Cancer | Metastatic Lung Cancer | Pancreas Adenocarcinoma | Metastatic Melanoma | Colon Cancer | Colonic Neoplasms | Pancreas Cancer | Non Small Cell Lung Cancer Metastatic | Neoplasm | Pancreas Neoplasm | Metastatic Pancreatic Cancer | Metastatic Colon Cancer and other conditions

United States
National Cancer Institute (NCI)

Completed

A Phase I, Pharmacological, and Biological Study of OSI-774 in Combination With FOLFOX 4 (5-FU, Leucovorin, and Oxaliplatin) and Bevacizumab (Avastin) in Patients With Advanced Colorectal Cancer

Mucinous Adenocarcinoma of the Rectum | Signet Ring Adenocarcinoma of the Rectum | Stage IIIA Rectal Cancer | Stage IIIB Rectal Cancer | Stage IIIC Rectal Cancer | Mucinous Adenocarcinoma of the Colon | Signet Ring Adenocarcinoma of the Colon | Stage IIIA Colon Cancer | Stage IIIB Colon Cancer | Stage... and other conditions

United States
Loxo Oncology, Inc.
Eli Lilly and Company

Recruiting

A Study of Selpercatinib (LOXO-292) in Participants With Advanced Solid Tumors, RET Fusion-Positive Solid Tumors, and Medullary Thyroid Cancer (LIBRETTO-001) (LIBRETTO-001)

Non-Small Cell Lung Cancer | Colon Cancer | Medullary Thyroid Cancer | Any Solid Tumor

United States, Japan, Taiwan, Australia, Korea, Republic of, Israel, Spain, Switzerland, Singapore, France, Canada, Italy, Germany, United Kingdom, Hong Kong, Denmark
Memorial Sloan Kettering Cancer Center

Active, not recruiting

Ascertainment of Peripheral Blood or Saliva Samples for Genetic Epidemiology Studies of Familial Cancers

Lymphoma, Non-Hodgkin | Uterine Cervical Neoplasms | Leukemia | Breast Neoplasms | Prostatic Neoplasms | Ovarian Neoplasms | Colonic Neoplasms

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Encorafenib, Cetuximab, and Nivolumab in Treating Patients With Microsatellite Stable, BRAFV600E Mutated Unresectable or Metastatic Colorectal Cancer

Progressive Disease | Recurrent Colorectal Carcinoma | Metastatic Colon Adenocarcinoma | Metastatic Rectal Adenocarcinoma | Stage IV Colorectal Cancer AJCC v8 | Stage IVA Colorectal Cancer AJCC v8 | Stage IVB Colorectal Cancer AJCC v8 | Stage IVC Colorectal Cancer AJCC v8 | Stage III Colorectal Cancer... and other conditions

United States
National Cancer Institute (NCI)

Completed

Vaccine Therapy in Treating Patients With Metastatic Cancer

Melanoma | Breast Cancer | Colorectal Cancer | Lung Cancer | Bone Cancer | Rectal Cancer | Uterine Sarcoma | Colon Cancer | Ovarian Sarcoma | Eye Cancer | Adult Soft Tissue Sarcoma

United States
Ohio State University Comprehensive Cancer Center

Completed

Single Incision Laparoscopic Surgery in Treating Patients With Colorectal Disease

Crohn Disease | Familial Adenomatous Polyposis | Stage IIIA Colon Cancer | Stage IIIB Colon Cancer | Stage IIIC Colon Cancer | Recurrent Colon Cancer | Stage I Colon Cancer | Stage IIA Colon Cancer | Stage IIB Colon Cancer | Stage IIC Colon Cancer | Adenomatous Polyp | Hereditary Intestinal Polyposis Syndrome

United States
National Cancer Institute (NCI)
Eastern Cooperative Oncology Group; Southwest Oncology Group

Completed

Irinotecan Compared With Combination Chemotherapy in Treating Patients With Advanced Colorectal Cancer

Mucinous Adenocarcinoma of the Rectum | Signet Ring Adenocarcinoma of the Rectum | Stage IIIA Rectal Cancer | Stage IIIB Rectal Cancer | Stage IIIC Rectal Cancer | Mucinous Adenocarcinoma of the Colon | Signet Ring Adenocarcinoma of the Colon | Stage IIIA Colon Cancer | Stage IIIB Colon Cancer | Stage... and other conditions

United States
PERROD Guillaume

Not yet recruiting

CAD-EYE System for the Detection of Neoplastic Lesions in Patients With Lynch Syndrome (CADLYNCH)

Lynch Syndrome
Genentech, Inc.

Recruiting

Study to Evaluate the Safety, Pharmacokinetics, and Activity of GDC-1971 in Combination With Either Osimertinib in Participants With Unresectable, Locally Advanced, or Metastatic Non-Small Cell Lung Cancer, or With Cetuximab in Participants With Metastatic Colorectal Cancer

Colorectal Cancer | Non-Small Cell Lung Cancer

Korea, Republic of, Australia, Canada, United States
Sixth Affiliated Hospital, Sun Yat-sen University

Recruiting

Postoperation Maintenance Therapy for Resectable Liver Metastases of Colorectal Cancer Guided by ctDNA

Colorectal Cancer | Liver Metastases | Circulating Tumor Cell | Cancer, Therapy-Related

China
Junjie Peng
Shanghai OrigiMed Co., Ltd.

Recruiting

Circulating Tumor DNA Guided Therapeutic Strategies for CRC Patients With Small Pulmonary Nodules

Advanced Colorectal Cancer | Circulating Tumor DNA

China
Sun Yat-sen University

Not yet recruiting

Preoperative Systemic Therapy for Colorectal Cancer Peritoneal Metastases

Colorectal Neoplasms | Colorectal Cancer | Peritoneal Neoplasms | Colorectal Cancer Metastatic | Chemotherapy Effect | Cytoreductive Surgery | Peritoneal Cancer | Peritoneal Metastases | Hyperthermic Intraperitoneal Chemotherapy

China
Dana-Farber Cancer Institute
National Cancer Institute (NCI); University of Massachusetts, Boston

Recruiting

Testing Home-based Exercise Strategies in Underserved Minority Cancer Patients Undergoing Chemotherapy: the THRIVE Study

Breast Cancer | Colorectal Cancer | Prostate Cancer

United States
University Medical Center Groningen
Technical University of Munich; Biomedical Research Foundation of the Academy... and other collaborators

Recruiting

Early Detection of Cancer Onset Based on Sensing Field Cancerization at the Organ Level in the Alimentary Tract Using an Integrated Stimulated Raman/Scattering Modality for Endoscopic Real-time in Vivo Measurements (SENSITIVE)

Colorectal Neoplasms | Carcinogenesis | Barrett Esophagus | Esophageal Adenocarcinoma | Colorectal Adenoma | Colorectal Adenocarcinoma | Colorectal Polyp

Netherlands
UNC Lineberger Comprehensive Cancer Center
University of North Carolina, Chapel Hill; National Center for Advancing Translational... and other collaborators

Recruiting

Overcoming Barriers to the Uptake of Cascade Screening for Lynch Syndrome: Workbook Feasibility Study

Lynch Syndrome

United States
National Cancer Centre, Singapore
Bristol-Myers Squibb

Recruiting

Neoantigen Dendritic Cell Vaccine and Nivolumab in HCC and Liver Metastases From CRC

Hepatocellular Carcinoma | Colorectal Cancer | Liver Metastases | Colorectal Carcinoma | Hepatocellular Cancer

Singapore
Fox Chase Cancer Center

Recruiting

Atorvastatin ± Aspirin in Lynch Syndrome Syndrome

Lynch Syndrome

United States
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI); Albert Einstein College of Medicine

Recruiting

Multi-Organ Screening Recommendations in Patients With Lynch Syndrome

Lynch Syndrome

United States
Radboud University Medical Center

Active, not recruiting

Dendritic Cell Vaccination in Patients With Lynch Syndrome or Colorectal Cancer With MSI

Colorectal Cancer

Netherlands
Vanderbilt University Medical Center

Enrolling by invitation

Visualization of the Papilla Through Use of the NuView Device in Patients With FAP (NuView)

Familial Adenomatous Polyposis

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Molecular Targeting of 15-Lipoxygenase-1 (15-LOX-1) for Apoptosis Induction in Human Colorectal Cancers

Familial Adenomatous Polyposis

United States
National Cancer Institute (NCI)

Completed

Review of Post-Study Clinical Endoscopy Reports in Follow Up to MAY2016-07-01

Familial Adenomatous Polyposis

United States
Eli Lilly and Company

Terminated

A Study of LY3499446 in Participants With Advanced Solid Tumors With KRAS G12C Mutation

Colorectal Cancer | Non-Small Cell Lung Cancer | Advanced Solid Tumor

United States, Australia
Second Affiliated Hospital, School of Medicine,...
Guangzhou Burning Rock Medical Examination Institute Co., Ltd.

Completed

Diagnosis of Lynch Syndrome Based on Next-generation Sequencing in Colorectal Cancer

Lynch Syndrome

China
Isarna Therapeutics GmbH

Completed

Safety and Tolerability of AP 12009, Administered I.V. in Patients With Advanced Tumors Known to Overproduce TGF-beta-2

Melanoma | Colorectal Neoplasms | Pancreatic Neoplasms

Germany

Clinical Trials on Kidney Failure, Chronic

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