Clinical Trials on LDL-hypercholesterolemia

Total 1284 results

Ikaria Bioscience Pty Ltd
SHANGHAI RONA Therapeutics Co.,Ltd.

Not yet recruiting

the Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamic Effects in Adult Subjects With Elevated LDL-C

To Reduce the LDL-C Level in Hypercholesteremia Patients
Ikaria Bioscience Pty Ltd

Recruiting

Adult Subjects With Elevated Low-Density Lipoprotein-Cholesterol to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamic Effects

To Reduce the LDL-C Level in Hypercholesteremia Adult Patients | Combination for Subgroup High LDL-c Patients With Other Comorbidities

Australia
Texas A&M University

Completed

Impact of Beef's Unique Food Matrix on Human Health

Cholesterol, LDL | Cholesterol, HDL | Research Subjects

United States
Dhurakij Pundit University

Recruiting

Effects of Phytoestrogen From Pueraria Mirifica in Improvement of Serum Lipid Parameters in Postmenopausal Women

Dyslipidemias | Hypercholesterolemia | Hypertriglyceridemia | Postmenopausal Symptoms | Hyper-LDL-cholesterolemia | Hypo HDL Cholesterolaemia

Thailand
Universiteit Antwerpen

Completed

the Effect of a Red Rice Nutrition Supplement on Cholesterol Levels

Cholesterol Level | HDL Level | LDL Level | TG Level

Belgium
Yonsei University

Completed

The Effectiveness of Plant Stanols as Ester on Change in Blood Cholesterol Level

LDL-cholesterol Level 130-159mg/dL
Merck Sharp & Dohme LLC

Completed

Effect of Statins on Lipid Levels Following the First Acute Coronary Event (MK-0000-204) (REMAINS)

Dyslipidemias | Hypercholesterolemia | Hypertriglyceridemia | High LDL-C | Low HDL-C
Arizona State University
North American Millers Association - Corn Division

Completed

Corn and Heart Health Study (CHS)

Gut Microbiome | Cholesterol, LDL | Cholesterol, HDL

United States
Novartis Pharmaceuticals

Completed

Safety, Pharmacokinetics and Pharmacodynamics of LGT209 in Healthy Volunteers With Elevated Cholesterol and in Hypercholesterolemic Patients Treated With Statins

Hypercholesterolemia | LDL Cholesterol

United States
Ludwig-Maximilians - University of Munich

Completed

Effect of Mipomersen on LDL-Cholesterol Levels in Patients Treated by Regular Apheresis (MICA)

Atherosclerosis | LDL-hypercholesterolemia

Germany
Alnylam Pharmaceuticals

Completed

Trial to Evaluate Safety and Tolerability of ALN-PCS02 in Subjects With Elevated LDL-Cholesterol (LDL-C)

Elevated LDL-Cholesterol (LDL-C)

United Kingdom
LIB Therapeutics LLC
Medpace, Inc.

Completed

Study to Evaluate Efficacy and Safety of LIB003 in Patients on Lipid-Lowering Therapy Needing Additional LDL-C Reduction

LDL Cholesterol

United States
Sanofi
Regeneron Pharmaceuticals

Completed

Usability Study of the Commercial Auto-injector Device and the New Auto-injector Device (SYDNEY) in Patients With High or Very High CV Risk With Hypercholesterolemia Not Adequately Controlled With Their Lipid-Modifying Therapy

Hypercholesterolaemia

United States
GlaxoSmithKline

Completed

Acotral® Versus Zetia® Ezetimibe Bioequivalance Study.

Hypercholesterolaemia

India
AstraZeneca

Completed

Registry On Efficacy and Safety Of Rosuvastatin, and Atorvastatin and Simvastatin In Hypercholesterolaemia

Hypercholesterolaemia

Singapore
AstraZeneca

Completed

PULSAR - A Prospective Study to Evaluate the Utility of Low Doses of the Statins Atorvastatin and Rosuvastatin.

Hypercholesterolaemia
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Carotid Atorvastatin Study in Hyperlipidemic Post-Menopausal Women

Hypercholesterolaemia

France, Belgium, Netherlands
AstraZeneca

Terminated

Study of Asian Patients With Hypercholesterolaemia in the UK - Rosuvastatin 5mg Versus Atorvastatin 10mg

Hypercholesterolaemia

United Kingdom
Akeso
AD Pharmaceuticals Co., Ltd.

Completed

A Study of PCSK9 Inhibitor AK102 in Healthy Subjects

Hypercholesterolaemia

China
GlaxoSmithKline

Completed

Rosuvastatin Calcium Bioequivalence Study - Fast

Hypercholesterolaemia

Brazil
AstraZeneca

Completed

Evaluation of Patients Treated With HMG-CoA Reductase Inhibitors to Reach Cholesterol Target Values

Hypercholesterolaemia

Bosnia and Herzegovina
AstraZeneca

Completed

Non-interventional Study (NIS) to Assess Reaching of Cholesterol Target Values in Patients Treated With HMG-CoA Reductase Inhibitors

Hypercholesterolaemia

Croatia
AstraZeneca

Completed

Rosuvastatin Efficacy and Safety Evaluation in Hypercholesterolaemic Patients (RESEARCH)

Hypercholesterolaemia

Greece
AstraZeneca

Completed

OLE Study to Evaluate Safety / Efficacy of ZD4522

Hypercholesterolaemia
Almond Board of California
KGK Science Inc.

Completed

Investigating the Dose Response of an Almond-enriched Diet on Optimizing HDL-C in a Population With Hypercholesterolemia

Hypercholesterolemia | HDL-C

Canada
Novartis Pharmaceuticals

Recruiting

Specified Drug-use Survey of Leqvio for s.c. Injection.

Hypercholesterolaemia | Familial Hypercholesterolaemia

Japan
Universidad de Granada
University of Copenhagen; University of Oxford; Harvard University; University... and other collaborators

Recruiting

Cardiovascular Risk Prevention With a Mediterranean Dietary Pattern Reduced in Saturated Fat (CADIMED)

LDL Cholesterol

Spain
Uppsala University
Dalarna County Council, Sweden

Completed

Effectiveness of Written Dietary Advice on Lipoproteins - a Pragmatic Randomized Controlled Trial (MYDICLIN)

Cholesterol, LDL

Sweden
Unity Health Toronto

Unknown

Effect of Viscous Soluble Fibers on Serum Cholesterol Levels (CHOL-META)

LDL Cholesterol

Canada
University of Texas Southwestern Medical Center
Merck Sharp & Dohme LLC; Donald W. Reynolds Foundation

Completed

Comparison of Efficacy and Safety of Ezetimibe or Statin Monotherapy to Co-Administration of Both

Cholesterol, LDL

United States
Amgen

Terminated

Study to Evaluate the Safety of Repatha® in Pregnancy

Pregnancy | Hypercholesterolaemia

Belgium, Denmark, Italy, Czechia, United Kingdom, Australia, Austria, Greece, Switzerland, Netherlands, Spain, Sweden, Slovakia, Norway
AstraZeneca

Withdrawn

ORBITAL: Open-Label Primary Care Study: Rosuvastatin Based Compliance Initiatives Linked To Achievement Of LDL Goals

Primary Hypercholesterolaemia
Jiangsu HengRui Medicine Co., Ltd.

Completed

The PK/PD Study of A Single Subcutaneous Injection of SHR-1209 in Healthy Subjects

Hypercholesteremia

China
AstraZeneca

Completed

Pattern of Statins Use in Catalonia

Hypercholesteremia
AstraZeneca

Completed

A Study Measuring Effects on Intima Media Thickness: An Evaluation of Rosuvastatin 40 mg (METEOR)

Hypercholesteremia

United States, France, Norway, Netherlands, Belgium, Germany, Finland, Czech Republic
AstraZeneca

Completed

Direct Statin Comparison of LDL-C Values: an Evaluation of Rosuvastatin Therapy

Hypercholesteremia

Belgium
AstraZeneca

Completed

C-Control: Efficacy and Safety of Therapy With Rosuvastatin in Statin-Naive and in Statin-Switched Patients

Hypercholesteremia
AstraZeneca

Completed

Centralized Pan-South African Survey on the Undertreatment of Hypercholesterolaemia (CEPHEUS)

Undertreatment of Hypercholesterolaemia

South Africa
The Cooper Institute
Cargill

Completed

Phytosterol Supplementation and Cardiovascular Risk

Hypercholesteremia

United States
NeuroBo Pharmaceuticals Inc.

Completed

A 12-Week, Phase 2 Study of Gemcabene in Hypercholesterolemia Patients on Stable Moderate and High-Intensity Statins (ROYAL-1)

Hypercholesteremia

United States
NeuroBo Pharmaceuticals Inc.

Completed

Effect of Gemcabene on the Pharmacokinetics of Atorvastatin in Healthy Volunteers

Hypercholesteremia
Ferrer Internacional S.A.

Terminated

Pharmacodynamic Clinical Trial of Cardiovascular Polypill on LDL Cholesterol

Elevated LDL Cholesterol

Spain
Organon and Co

Completed

TWICE (Ezetimibe Together With Any Statin Cholesterol Enhancement)(0653-060)

Hypercholesterolaemia | Hyperlipidaemia
Danone Research

Completed

Pilot Study in the Cholesterol Absorption Reduction After Consumption of Low-fat, Drinkable Fermented Milk Enriched With Plant Sterols

Mildly Hypercholesterolemic Subjects

Canada
Danone Research

Completed

Effects of Fermented Milk Product Enriched With Plant Sterols and Policosanols in Mild Hypercholesterolaemic Adults

Mildly Hypercholesterolemic Subjects

United Kingdom
Danone Research

Completed

Effect of the Consumption of a Fermented Milk Enriched With Plant Sterols (Italy)

Mildly Hypercholesterolemic Subjects

Italy
Amgen

Completed

Chart Review of Repatha® in Subjects With Hyperlipidaemia (HEYMANS)

Hypercholesterolaemia

Austria, Italy, Belgium, Czechia, Switzerland, Spain, Slovakia, Germany, Portugal, Greece, Bulgaria, Sweden
Novo Nordisk A/S

Completed

A Research Study Investigating How NNC0385-0434 is Tolerated in People With or Without High Cholesterol Levels

Healthy Volunteers | Hypercholesterolaemia

United Kingdom
Iuliu Hatieganu University of Medicine and Pharmacy

Completed

Comparing a Low-GI Nutrigenetic and Ketogenic Diet for Weight Loss With 18 Month Follow-up (LOWGI_GENE)

Weight Loss | Glucose, High Blood | LDL Hyperlipoproteinemia | HDL | Triglycerides High
Ferrer Internacional S.A.

Terminated

A Pharmacodynamic Study to Evaluate the Effect of a Fixed Dose Combination Pill on Low Density Lipoprotein (LDL) Cholesterol

Elevated LDL Cholesterol

United States

Clinical Trials on LDL-hypercholesterolemia

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